{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T12:02:55Z","timestamp":1790510575381,"version":"4.1.0"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T00:00:00Z","timestamp":1636675200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Chem."],"abstract":"<jats:p>The synthesis and characterization of a novel florescent chemosensor <jats:bold>1<\/jats:bold> with two different types of cationic binding sites have been reported in this work, which is a calix[4]crown derivative in 1,3-alternate conformation bearing two 2-phenyl-5-(4-dimethylaminopyenyl)-1,3,4-oxadiazole units. The recognition behaviors of <jats:bold>1<\/jats:bold> in dichloromethane\/acetonitrile solution to alkali metal ions (Na<jats:sup>+<\/jats:sup> and K<jats:sup>+<\/jats:sup>), alkaline earth metal ions (Mg<jats:sup>2+<\/jats:sup> and Ca<jats:sup>2+<\/jats:sup>), and transition metal ions (Co<jats:sup>2+<\/jats:sup>, Ni<jats:sup>2+<\/jats:sup>, Zn<jats:sup>2+<\/jats:sup>, Cd<jats:sup>2+<\/jats:sup>, Cu<jats:sup>2+<\/jats:sup>, Mn<jats:sup>2+<\/jats:sup>, and Ag<jats:sup>+<\/jats:sup>) have been investigated by UV-Vis and fluorescence spectra. The fluorescence of <jats:bold>1<\/jats:bold> might be quenched selectively by Cu<jats:sup>2+<\/jats:sup> due to the photo-induced electron transfer mechanism, and the quenched emission from <jats:bold>1<\/jats:bold> could be partly revived by the addition of Ca<jats:sup>2+<\/jats:sup> or Mg<jats:sup>2+<\/jats:sup>; thus, the receptor <jats:bold>1<\/jats:bold> might be worked as an on\u2013off switchable fluorescent chemosensor triggered by metal ion exchange.<\/jats:p>","DOI":"10.3389\/fchem.2021.766442","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T04:25:24Z","timestamp":1636691124000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["A Novel Calix[4]Crown-Based 1,3,4-Oxadiazole as a Fluorescent Chemosensor for Copper(II) Ion Detection"],"prefix":"10.3389","volume":"9","author":[{"given":"Chun","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianze","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"856","DOI":"10.3389\/fchem.2019.00856","article-title":"Structural Design, Synthesis, and Preliminary Biological Evaluation of Novel Dihomooxacalix[4]arene-Based Anti-tumor Agent","volume":"7","author":"An","year":"2019","journal-title":"Front. 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