{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:43:10Z","timestamp":1792759390090,"version":"4.5.0"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Chem."],"abstract":"<jats:p>We have designed and synthesized a novel simple colorimetric fluorescent probe with aggregation-induced emission (AIE) properties. Probe 5-(4-(diphenylamine)phenyl) thiophen-2-formaldehyde <jats:bold>W<\/jats:bold> exhibited a turn-on fluorescent response to cyanide ion (CN<jats:sup>\u2212<\/jats:sup>), which induces distinct visual color changes. Probe <jats:bold>W<\/jats:bold> exhibited a highly selective and sensitive ratiometric fluorescence response for the detection of CN<jats:sup>\u2212<\/jats:sup> over a wide pH range (4\u201311) and in the presence of common interferents. The linear detection of CN<jats:sup>\u2212<\/jats:sup> over the concentration range of 4.00\u201338.00\u00a0\u00b5M (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.9916, RSD = 0.02) was monitored by UV-Vis absorption spectrometry (UV-Vis) with the limit of detection determined to be 0.48\u00a0\u00b5M. The linear detection of CN<jats:sup>\u2212<\/jats:sup> over the concentration range of 8.00\u201338.00\u00a0\u00b5M was examined by fluorescence spectrophotometry (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.99086, RSD = 0.031), and the detection limit was found to be 68.00\u00a0nM. The sensing mechanisms were confirmed by <jats:sup>1<\/jats:sup>H NMR spectroscopic titrations, X-ray crystallographic analysis, and HRMS. Importantly, probe <jats:bold>W<\/jats:bold> was found to show rapid response, high selectivity, and sensitivity for cyanide anions in real water samples, over the range of 100.17\u223c100.86% in artificial lake water and 100.54\u223c101.64% in running water by UV-Vis absorption spectrometry, and over the range of 99.42\u223c100.71% in artificial lake water and 100.59\u223c101.17% in running water by fluorescence spectrophotometry. Importantly, this work provides a simple and effective approach which uses an economically cheap and uncomplicated synthetic route for the selective, sensitive, and quantitative detection of CN<jats:sup>\u2212<\/jats:sup> ions in systems relevant to the environment and health.<\/jats:p>","DOI":"10.3389\/fchem.2022.923149","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T05:12:05Z","timestamp":1658121125000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":26,"title":["A Turn-On Fluorescent Chemosensor for Cyanide Ion Detection in Real Water Samples"],"prefix":"10.3389","volume":"10","author":[{"given":"Qing","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shou-Ting","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Yong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Jiong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Long","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.jlumin.2016.07.038","article-title":"A Single Optical Sensor with High Sensitivity for Detection of Fe3+ and CN\u2212 Ions","volume":"179","author":"Afshani","year":"2016","journal-title":"J. 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