{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:28:31Z","timestamp":1790810911935,"version":"4.1.0"},"reference-count":58,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T00:00:00Z","timestamp":1692144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003741","name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003741","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Chem."],"abstract":"<jats:p>This paper provides a conceptual roadmap for the use of hormonal bioinspired models in a broad range of AI, neuroengineering, or computational systems. The functional signaling nature of hormones provides an example of a reliable multidimensional information management system that can solve parallel multitasks. Two existing examples of hormonal computing bioinspired possibilities are shortly reviewed, and two novel approaches are introduced, with a special emphasis on what researchers propose as hormonal computing for neurorehabilitation in patients with complete spinal cord injuries. They extend the use of epidural electrical stimulation (EES) by applying sequential stimulations to limbs through prostheses. The prostheses include various limb models and are connected to a neurostimulation bus called the central pattern generator (CPG). The CPG bus utilizes hormonal computing principles to coordinate the stimulation of the spinal cord and muscles.<\/jats:p>","DOI":"10.3389\/fchem.2023.1232949","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T14:09:32Z","timestamp":1692281372000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Hormonal computing: a conceptual approach"],"prefix":"10.3389","volume":"11","author":[{"given":"Jordi","family":"Vallverd\u00fa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Talanov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey","family":"Leukhin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Fatykhova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Erokhin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,8,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"104304","DOI":"10.1016\/j.biosystems.2020.104304","article-title":"Reactive fungal wearable","volume":"199","author":"Adamatzky","year":"2021","journal-title":"Biosystems"},{"key":"B2","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1179\/1743280414Y.0000000030","article-title":"Micropackaging via layer-by-layer assembly: Microcapsules and microchamber arrays","volume":"59","author":"Antipina","year":"2014","journal-title":"Int. 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