{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T06:17:52Z","timestamp":1766902672967},"reference-count":39,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2017.00102","type":"journal-article","created":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T23:38:51Z","timestamp":1490830731000},"update-policy":"http:\/\/dx.doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Sequencing of blaIMP-Carrying IncN2 Plasmids, and Comparative Genomics of IncN2 Plasmids Harboring Class 1 Integrons"],"prefix":"10.3389","volume":"7","author":[{"given":"Xiaoyuan","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuyun","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haihong","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yigang","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Defu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weijun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajun","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinglin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuiping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongsheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2017,3,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"W29","DOI":"10.1093\/nar\/gkt282","article-title":"BLAST: a more efficient report with usability improvements","volume":"41","author":"Boratyn","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"B2","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/978-1-4939-3167-5_2","article-title":"UniProtKB\/Swiss-Prot, the manually annotated section of the UniProt KnowledgeBase: how to use the entry view","volume":"1374","author":"Boutet","year":"2016","journal-title":"Methods Mol. Biol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"8365","DOI":"10.1038\/srep08365","article-title":"RASTtk: a modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes","volume":"5","author":"Brettin","year":"2015","journal-title":"Sci. Rep"},{"key":"B4","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1089\/mdr.2010.0042","article-title":"Transposons related to Tn1696 in IncHI2 plasmids in multiply antibiotic resistant Salmonella enterica serovar Typhimurium from Australian animals","volume":"16","author":"Cain","year":"2010","journal-title":"Microb. Drug Resist."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e48737","DOI":"10.1371\/journal.pone.0048737","article-title":"Sequence of closely related plasmids encoding blaNDM\u22121 in two unrelated Klebsiella pneumoniae isolates in Singapore","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS ONE"},{"key":"B6","doi-asserted-by":"publisher","first-page":"7212","DOI":"10.1038\/srep07212","article-title":"IMP-1 encoded by a novel Tn402-like class 1 integron in clinical Achromobacter xylosoxidans, China","volume":"4","author":"Chen","year":"2014","journal-title":"Sci. Rep."},{"key":"B7","doi-asserted-by":"publisher","first-page":"294","DOI":"10.3389\/fmicb.2015.00294","article-title":"NDM-1 encoded by a pNDM-BJ01-like plasmid p3SP-NDM in clinical Enterobacter aerogenes","volume":"6","author":"Chen","year":"2015","journal-title":"Front. Microbiol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1093\/nar\/gki297","article-title":"The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen","volume":"33","author":"Chiu","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"B9","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Fifth Informational Supplement M100\u2013S25","author":"CLSI","year":"2015"},{"key":"B10","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1128\/AAC.39.1.155","article-title":"Expression of antibiotic resistance genes in the integrated cassettes of integrons","volume":"39","author":"Collis","year":"1995","journal-title":"Antimicrob. Agents Chemother."},{"key":"B11","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1006\/jmbi.1997.1124","article-title":"Organization of the leading region of IncN plasmid pKM101 (R46): a regulation controlled by CUP sequence elements","volume":"271","author":"Delver","year":"1997","journal-title":"J. Mol. Biol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4161\/mge.22967","article-title":"Integrons: vehicles and pathways for horizontal dissemination in bacteria","volume":"2","author":"Domingues","year":"2012","journal-title":"Mob. Genet. Elem."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.1093\/jac\/dkv232","article-title":"Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii","volume":"70","author":"Feng","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"key":"B15","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1128\/AEM.02272-07","article-title":"Critical evaluation of two primers commonly used for amplification of bacterial 16S rRNA genes","volume":"74","author":"Frank","year":"2008","journal-title":"Appl. Environ. Microbiol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"5095","DOI":"10.1128\/JB.00152-08","article-title":"The evolution of class 1 integrons and the rise of antibiotic resistance","volume":"190","author":"Gillings","year":"2008","journal-title":"J. Bacteriol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1128\/MMBR.00056-13","article-title":"Integrons: past, present, and future","volume":"78","author":"Gillings","year":"2014","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B18","doi-asserted-by":"publisher","first-page":"D566","DOI":"10.1093\/nar\/gkw1004","article-title":"CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database","volume":"45","author":"Jia","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1093\/bioinformatics\/btp105","article-title":"INTEGRALL: a database and search engine for integrons, integrases and gene cassettes","volume":"25","author":"Moura","year":"2009","journal-title":"Bioinformatics"},{"key":"B21","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/gb4173","article-title":"On the middle ground between open source and commercial software - the case of the Newbler program","volume":"15","author":"Nederbragt","year":"2014","journal-title":"Genome Biol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1111\/j.1574-6968.1998.tb13345.x","article-title":"An integron of class 1 is present on the plasmid pCG4 from gram-positive bacterium Corynebacterium glutamicum","volume":"169","author":"Nesvera","year":"1998","journal-title":"FEMS Microbiol. Lett."},{"key":"B23","doi-asserted-by":"publisher","first-page":"3161","DOI":"10.1093\/jac\/dku275","article-title":"Characterization of an IncN2-type blaNDM-1-carrying plasmid in Escherichia coli ST131 and Klebsiella pneumoniae ST11 and ST15 isolates in Thailand","volume":"69","author":"Netikul","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"B24","doi-asserted-by":"publisher","first-page":"D733","DOI":"10.1093\/nar\/gkv1189","article-title":"Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation","volume":"44","author":"O'leary","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"B25","doi-asserted-by":"publisher","first-page":"D737","DOI":"10.1093\/nar\/gkt1252","article-title":"BacMet: antibacterial biocide and metal resistance genes database","volume":"42","author":"Pal","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1128\/AAC.45.4.1263-1270.2001","article-title":"Transposons Tn1696 and Tn21 and their integrons In4 and In2 have independent origins","volume":"45","author":"Partridge","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"key":"B27","doi-asserted-by":"publisher","first-page":"6371","DOI":"10.1128\/JB.185.21.6371-6384.2003","article-title":"The IS1111 family members IS4321 and IS5075 have subterminal inverted repeats and target the terminal inverted repeats of Tn21 family transposons","volume":"185","author":"Partridge","year":"2003","journal-title":"J. Bacteriol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"2166","DOI":"10.1128\/AAC.05796-11","article-title":"pJIE137 carrying blaCTX\u2212M\u221262 is closely related to p271A carrying blaNDM\u22121","volume":"56","author":"Partridge","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"B29","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1111\/j.1574-6976.2009.00175.x","article-title":"Gene cassettes and cassette arrays in mobile resistance integrons","volume":"33","author":"Partridge","year":"2009","journal-title":"FEMS Microbiol. Rev."},{"key":"B30","doi-asserted-by":"publisher","first-page":"4224","DOI":"10.1128\/AAC.00165-11","article-title":"Analysis of the resistome of a multidrug-resistant NDM-1-producing Escherichia coli strain by high-throughput genome sequencing","volume":"55","author":"Poirel","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"B31","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.plasmid.2008.08.001","article-title":"Revised nomenclature for transposable genetic elements","volume":"60","author":"Roberts","year":"2008","journal-title":"Plasmid"},{"key":"B32","doi-asserted-by":"publisher","first-page":"D32","DOI":"10.1093\/nar\/gkj014","article-title":"ISfinder: the reference centre for bacterial insertion sequences","volume":"34","author":"Siguier","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"B33","doi-asserted-by":"publisher","first-page":"458","DOI":"10.3389\/fmicb.2015.00458","article-title":"Production of plasmid-encoding NDM-1 in clinical Raoultella ornithinolytica and Leclercia adecarboxylata from China","volume":"6","author":"Sun","year":"2015","journal-title":"Front. Microbiol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1093\/jac\/dkv356","article-title":"Lateral dissemination and inter-patient transmission of blaKPC\u22123: role of a conjugative plasmid in spreading carbapenem resistance","volume":"71","author":"Tijet","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1128\/aac.01297-12","article-title":"Complete sequence of the IncT-type plasmid pT-OXA-181 carrying the blaOXA\u2212181 carbapenemase gene from Citrobacter freundii","volume":"57","author":"Villa","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1111\/j.1365-2958.2011.07648.x","article-title":"Transcription of integron-harboured gene cassette impacts integration efficiency in class 1 integron","volume":"80","author":"Wei","year":"2011","journal-title":"Mol. Microbiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1093\/jac\/dks261","article-title":"Identification of acquired antimicrobial resistance genes","volume":"67","author":"Zankari","year":"2012","journal-title":"J. Antimicrob. Chemother"},{"key":"B38","doi-asserted-by":"publisher","first-page":"873","DOI":"10.2217\/fmb.15.18","article-title":"Acquired metallo-beta-lactamases and their genetic association with class 1 integrons and ISCR elements in Gram-negative bacteria","volume":"10","author":"Zhao","year":"2015","journal-title":"Future Microbiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"3039","DOI":"10.1128\/AAC.00041-10","article-title":"ISEcp1-mediated transposition and homologous recombination can explain the context of blaCTX\u2212M\u221262 linked to qnrB2","volume":"54","author":"Zong","year":"2010","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00102\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T23:38:51Z","timestamp":1490830731000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00102\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,30]]},"references-count":39,"URL":"https:\/\/doi.org\/10.3389\/fcimb.2017.00102","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,30]]}}}