{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T08:57:54Z","timestamp":1785920274708,"version":"3.56.0"},"reference-count":41,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2017.00188","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T03:52:49Z","timestamp":1495079569000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Spreading of Pandemic Vibrio parahaemolyticus O3:K6 and Its Serovariants: A Re-analysis of Strains Isolated from Multiple Studies"],"prefix":"10.3389","volume":"7","author":[{"given":"Dongsheng","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanli","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiyun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongxu","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1099\/jmm.0.2008\/004275-0","article-title":"Characteristics of a pandemic clone of O3:K6 and O4:K68 Vibrio parahaemolyticus isolated in Beira, Mozambique","volume":"57","author":"Ansaruzzaman","year":"2008","journal-title":"J. Med. Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"3924","DOI":"10.1111\/j.1365-294X.2010.04782.x","article-title":"Origins and colonization history of pandemic Vibrio parahaemolyticus in South America","volume":"19","author":"Ansede-Bermejo","year":"2010","journal-title":"Mol. Ecol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1056\/nejm197901043000101","article-title":"Disease caused by a marine Vibrio. Clinical characteristics and epidemiology","volume":"300","author":"Blake","year":"1979","journal-title":"N. Engl. J. Med."},{"key":"B4","volume-title":"Methods for Antimicrobial Dilution and Dusk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria; Approved Guideline, 2nd Edn. M45\u20132A","year":"2010"},{"key":"B5","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.ijfoodmicro.2011.12.001","article-title":"Molecular typing of Vibrio parahaemolyticus isolates from the middle-east coastline of China","volume":"153","author":"Chen","year":"2012","journal-title":"Int. J. Food Microbiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.cmi.2015.11.003","article-title":"Serology, virulence, antimicrobial susceptibility and molecular characteristics of clinical Vibrio parahaemolyticus strains circulating in southeastern China from 2009 to 2013","volume":"22","author":"Chen","year":"2016","journal-title":"Clin. Microbiol. Infect."},{"key":"B7","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1186\/1471-2180-10-274","article-title":"Genetic analysis of the capsule polysaccharide (K antigen) and exopolysaccharide genes in pandemic Vibrio parahaemolyticus O3:K6","volume":"10","author":"Chen","year":"2010","journal-title":"BMC Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1089\/fpd.2012.1340","article-title":"Isolation and characterization of pandemic and nonpandemic strains of Vibrio parahaemolyticus from an outbreak of diarrhea in North 24 Parganas, West Bengal, India","volume":"10","author":"Chowdhury","year":"2013","journal-title":"Foodborne Pathog. Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1093\/molbev\/msv009","article-title":"Epidemic clones, Oceanic gene pools, and Eco-LD in the free living Marine pathogen Vibrio parahaemolyticus","volume":"32","author":"Cui","year":"2015","journal-title":"Mol. Biol. Evol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"221","DOI":"10.3389\/fmicb.2015.00221","article-title":"A pandemic Vibrio parahaemolyticus O3:K6 clone causing most associated diarrhea cases in the Pacific Northwest coast of Mexico","volume":"6","author":"de Jes\u00fas Hern\u00e1ndez-D\u00edaz","year":"2015","journal-title":"Front. Microbiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.fm.2016.02.008","article-title":"Antibiotic resistance of Vibrio parahaemolyticus and Vibrio vulnificus in various countries: a review","volume":"57","author":"Elmahdi","year":"2016","journal-title":"Food Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"708","DOI":"10.3389\/fmicb.2015.00708","article-title":"Highly diverse recombining populations of Vibrio cholerae and Vibrio parahaemolyticus in French Mediterranean coastal lagoons","volume":"6","author":"Esteves","year":"2015","journal-title":"Front. Microbiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1128\/JB.186.5.1518-1530.2004","article-title":"eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data","volume":"186","author":"Feil","year":"2004","journal-title":"J. Bacteriol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1089\/fpd.2015.2098","article-title":"Population relationship of Vibrio parahaemolyticus isolates derived from aquaculture ponds, a Seafood market, restaurants, and clinical samples","volume":"13","author":"Gao","year":"2016","journal-title":"Foodborne Pathog. Dis."},{"key":"B15","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.ijid.2006.08.003","article-title":"O3:K6 serotype of Vibrio parahaemolyticus identical to the global pandemic clone associated with diarrhea in Peru","volume":"11","author":"Gil","year":"2007","journal-title":"Int. J. Infect. Dis."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2831","DOI":"10.1128\/JB.01808-07","article-title":"Determination of molecular phylogenetics of Vibrio parahaemolyticus strains by multilocus sequence typing","volume":"190","author":"Gonzalez-Escalona","year":"2008","journal-title":"J. Bacteriol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"e0169722","DOI":"10.1371\/journal.pone.0169722","article-title":"Genetic analysis of Vibrio parahaemolyticus O3:K6 strains that have been isolated in Mexico since 1998","volume":"12","author":"Guerrero","year":"2017","journal-title":"PLoS ONE"},{"key":"B18","doi-asserted-by":"publisher","first-page":"125","DOI":"10.3389\/fmicb.2015.00125","article-title":"Characterization of Vibrio parahaemolyticus clinical strains from Maryland (2012\u20132013) and comparisons to a locally and globally diverse V. parahaemolyticus strains by whole-genome sequence analysis","volume":"6","author":"Haendiges","year":"2015","journal-title":"Front. Microbiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"291","DOI":"10.3389\/fmicb.2015.00291","article-title":"Prevalence and genetic diversity of clinical Vibrio parahaemolyticus isolates from China, revealed by multilocus sequence typing scheme","volume":"6","author":"Han","year":"2015","journal-title":"Front. Microbiol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1186\/1471-2164-9-570","article-title":"Genome plasticity of Vibrio parahaemolyticus: microevolution of the \u2018pandemic group\u2019","volume":"9","author":"Han","year":"2008","journal-title":"BMC Genomics"},{"key":"B21","doi-asserted-by":"publisher","first-page":"163","DOI":"10.3201\/eid1502.071269","article-title":"Epidemiology of Vibrio parahaemolyticus outbreaks, southern Chile","volume":"15","author":"Harth","year":"2009","journal-title":"Emerg. Infect. Dis."},{"key":"B22","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1089\/fpd.2011.1018","article-title":"Isolation, molecular characterization, and antibiotic susceptibility of Vibrio parahaemolyticus in Korean seafood","volume":"9","author":"Jun","year":"2012","journal-title":"Foodborne Pathog. Dis."},{"key":"B23","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1093\/infdis\/jiu059","article-title":"Bacteriophage therapy of a Vibrio parahaemolyticus infection caused by a multiple-antibiotic-resistant O3:K6 pandemic clinical strain","volume":"210","author":"Jun","year":"2014","journal-title":"J. Infect. Dis."},{"key":"B24","doi-asserted-by":"publisher","first-page":"564","DOI":"10.3389\/fmicb.2015.00564","article-title":"Examination of clinical and environmental Vibrio parahaemolyticus isolates by multi-locus sequence typing (MLST) and multiple-locus variable-number tandem-repeat analysis (MLVA)","volume":"6","author":"L\u00fcdeke","year":"2015","journal-title":"Front. Microbiol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.ijfoodmicro.2014.12.009","article-title":"Phenotypic and phylogenetic analysis of Vibrio parahaemolyticus isolates recovered from diarrhea cases in Guangdong Province, China","volume":"200","author":"Li","year":"2015","journal-title":"Int. J. Food Microbiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"787","DOI":"10.3389\/fmicb.2016.00787","article-title":"Vibrio parahaemolyticus strains of pandemic serotypes identified from clinical and environmental samples from Jiangsu, China","volume":"7","author":"Li","year":"2016","journal-title":"Front. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"685","DOI":"10.3201\/eid2004.130744","article-title":"Vibrio parahaemolyticus, Southern Coastal Region of China, 2007\u20132012","volume":"20","author":"Li","year":"2014","journal-title":"Emerg. Infect. Dis."},{"key":"B28","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.meegid.2016.01.006","article-title":"Serogroup, virulence, and molecular traits of Vibrio parahaemolyticus isolated from clinical and cockle sources in northeastern Thailand","volume":"39","author":"Mala","year":"2016","journal-title":"Infect. Genet. Evol."},{"key":"B29","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1128\/JCM.37.8.2473-2478.1999","article-title":"Comparison of molecular methods for typing Vibrio parahaemolyticus","volume":"37","author":"Marshall","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"B30","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1128\/JCM.38.2.578-585.2000","article-title":"Pandemic spread of an O3:K6 clone of Vibrio parahaemolyticus and emergence of related strains evidenced by arbitrarily primed PCR and toxRS sequence analyses","volume":"38","author":"Matsumoto","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1128\/CMR.00025-06","article-title":"Global dissemination of Vibrio parahaemolyticus serotype O3:K6 and its serovariants","volume":"20","author":"Nair","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"key":"B32","doi-asserted-by":"crossref","first-page":"3150","DOI":"10.1128\/JCM.35.12.3150-3155.1997","article-title":"Emergence of a unique O3:K6 clone of Vibrio parahaemolyticus in Calcutta, India, and isolation of strains from the same clonal group from Southeast Asian travelers arriving in Japan","volume":"35","author":"Okuda","year":"1997","journal-title":"J. Clin. Microbiol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1348-0421.2008.00027.x","article-title":"Genetic analyses of the putative O and K antigen gene clusters of pandemic Vibrio parahaemolyticus","volume":"52","author":"Okura","year":"2008","journal-title":"Microbiol. Immunol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1111\/j.1758-2229.2010.00134.x","article-title":"Prevalence, serotyping and molecular characterization of Vibrio parahaemolyticus in mussels from Italian growing areas, Adriatic Sea","volume":"2","author":"Ottaviani","year":"2010","journal-title":"Environ. Microbiol. Rep."},{"key":"B35","doi-asserted-by":"publisher","first-page":"e2815","DOI":"10.1371\/journal.pntd.0002815","article-title":"Trends in the Epidemiology of Pandemic and Non-pandemic Strains of Vibrio parahaemolyticus Isolated from Diarrheal Patients in Kolkata, India","volume":"8","author":"Pazhani","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"B36","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1007\/s00248-013-0201-8","article-title":"Isolation of Pandemic Vibrio parahaemolyticus from UK water and shellfish produce","volume":"65","author":"Powell","year":"2013","journal-title":"Microb. Ecol."},{"key":"B37","first-page":"2733","article-title":"Antimicrobial resistance and virulence characteristics of Vibrio parahaemolyticus","volume":"93","author":"Sun","year":"2013","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"B38","doi-asserted-by":"publisher","first-page":"110","DOI":"10.3389\/fcimb.2013.00110","article-title":"Pandemic Vibrio parahaemolyticus O3:K6 on the American continent","volume":"3","author":"Velazquez-Roman","year":"2014","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1089\/fpd.2007.0045","article-title":"Occurrence of pandemic clones of Vibrio parahaemolyticus isolates from seafood and clinical samples in a Chinese coastal province","volume":"5","author":"Vongxay","year":"2008","journal-title":"Foodborne Pathog. Dis."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1089\/fpd.2011.0865","article-title":"Vibrio parahaemolyticus isolates from Southeastern Chinese coast are genetically diverse with circulation of clonal complex 3 strains since 2002","volume":"8","author":"Yu","year":"2011","journal-title":"Foodborne Pathog. Dis."},{"key":"B41","doi-asserted-by":"publisher","first-page":"264","DOI":"10.7883\/yoken.67.264","article-title":"Analysis of bacterial pathogens causing acute diarrhea on the basis of sentinel surveillance in Shanghai, China, 2006-2011","volume":"67","author":"Zhang","year":"2014","journal-title":"Jpn. J. Infect. Dis."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00188\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:57:34Z","timestamp":1602118654000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00188\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,18]]},"references-count":41,"alternative-id":["10.3389\/fcimb.2017.00188"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2017.00188","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,18]]},"article-number":"188"}}