{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:15:49Z","timestamp":1790802949783,"version":"4.1.0"},"reference-count":57,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2017.00453","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T04:20:14Z","timestamp":1508991614000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":68,"title":["Cold-Shock Domain Family Proteins (Csps) Are Involved in Regulation of Virulence, Cellular Aggregation, and Flagella-Based Motility in Listeria monocytogenes"],"prefix":"10.3389","volume":"7","author":[{"given":"Athmanya K.","family":"Eshwar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Guldimann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Oevermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taurai","family":"Tasara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,10,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/j.1469-0691.2009.03109.x","article-title":"Listeriosis: a resurgent foodborne infection","volume":"16","author":"Allerberger","year":"2010","journal-title":"Clin. Microbiol. Infect."},{"key":"B2","doi-asserted-by":"publisher","first-page":"4634","DOI":"10.2903\/j.efsa.2015.4329","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2015","volume":"14","year":"2016","journal-title":"EFSA J."},{"key":"B3","doi-asserted-by":"publisher","first-page":"7784","DOI":"10.1073\/pnas.97.14.7784","article-title":"Escherichia coli CspA-family RNA chaperones are transcription antiterminators","volume":"97","author":"Bae","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B4","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1099\/mic.0.000243","article-title":"MsaB activates capsule production at the transcription level in Staphylococcus aureus","volume":"162","author":"Batte","year":"2016","journal-title":"Microbiology"},{"key":"B5","doi-asserted-by":"publisher","first-page":"5530","DOI":"10.1128\/IAI.73.9.5530-5539.2005","article-title":"Role of FliF and FliI of Listeria monocytogenes in flagellar assembly and pathogenicity","volume":"73","author":"Bigot","year":"2005","journal-title":"Infect. Immun."},{"key":"B6","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1111\/j.1365-2958.1993.tb01211.x","article-title":"Dual roles of plcA in Listeria monocytogenes pathogenesis","volume":"8","author":"Camilli","year":"1993","journal-title":"Mol. Microbiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"6484","DOI":"10.1128\/AEM.00897-07","article-title":"Microarray-based characterization of the Listeria monocytogenes cold regulon in log- and stationary-phase cells","volume":"73","author":"Chan","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.mib.2011.01.005","article-title":"Regulation of Listeria virulence: PrfA master and commander","volume":"14","author":"de las Heras","year":"2011","journal-title":"Curr. Opin. Microbiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.fm.2014.09.004","article-title":"Role of csp genes in NaCl, pH, and ethanol stress response and motility in Clostridium botulinum ATCC 3502","volume":"46","author":"Derman","year":"2015","journal-title":"Food Microbiol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"3237","DOI":"10.1128\/IAI.72.6.3237-3244.2004","article-title":"Role of flagellin and the two-component CheA\/CheY system of Listeria monocytogenes in host cell invasion and virulence","volume":"72","author":"Dons","year":"2004","journal-title":"Infect. Immun."},{"key":"B11","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1111\/j.1365-2958.1995.tb02297.x","article-title":"Entry of Listeria monocytogenes into hepatocytes requires expression of inIB, a surface protein of the internalin multigene family","volume":"16","author":"Dramsi","year":"1995","journal-title":"Mol. Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/jobm.201100335","article-title":"Flagella and bacterial pathogenicity","volume":"53","author":"Duan","year":"2013","journal-title":"J. Basic Microbiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1937-6448(08)01401-9","article-title":"New insights into determinants of Listeria monocytogenes virulence","volume":"270","author":"Dussurget","year":"2008","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"31651","DOI":"10.1074\/jbc.M102855200","article-title":"Escherichia coli poly(A)-binding proteins that interact with components of degradosomes or impede RNA decay mediated by polynucleotide phosphorylase and RNase, E","volume":"276","author":"Feng","year":"2001","journal-title":"J. Biol. Chem."},{"key":"B15","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/nrmicro2171","article-title":"Listeria monocytogenes- from saprophyte to intracellular pathogen","volume":"7","author":"Freitag","year":"2009","journal-title":"Nat. Rev. Microbiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1016\/0092-8674(91)90009-N","article-title":"Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci","volume":"65","author":"Gaillard","year":"1991","journal-title":"Cell"},{"key":"B17","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1126\/science.1063447","article-title":"Comparative genomics of Listeria species","volume":"294","author":"Glaser","year":"2001","journal-title":"Science"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1007\/s00018-007-6388-4","article-title":"Structure and function of bacterial cold shock proteins","volume":"64","author":"Horn","year":"2007","journal-title":"Cell. Mol. Life Sci."},{"key":"B19","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1111\/1541-4337.12092","article-title":"Listeria monocytogenes in aquatic food products\u2014a review","volume":"13","author":"Jami","year":"2015","journal-title":"Comp. Rev. Food Sci. Food Saf."},{"key":"B20","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1074\/jbc.272.1.196","article-title":"CspA, the major cold-shock protein of Escherichia coli, is an RNA chaperone","volume":"272","author":"Jiang","year":"1997","journal-title":"J. Biol. Chem."},{"key":"B21","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/S0092-8674(02)00905-4","article-title":"An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes","volume":"110","author":"Johansson","year":"2002","journal-title":"Cell"},{"key":"B22","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1078\/1438-4221-00173","article-title":"The role of motility as a virulence factor in bacteria","volume":"291","author":"Josenhans","year":"2002","journal-title":"Int. J. Med. Microbiol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.3389\/fmicb.2016.01151","article-title":"Cold shock proteins: a minireview with special emphasis on Csp-family of Enteropathogenic yersinia","volume":"7","author":"Keto-Timonen","year":"2016","journal-title":"Front. Microbiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","article-title":"Stages of embryonic development of the zebrafish","volume":"203","author":"Kimmel","year":"1995","journal-title":"Dev. Dyn."},{"key":"B25","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/0092-8674(92)90188-I","article-title":"L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein","volume":"68","author":"Kocks","year":"1992","journal-title":"Cell"},{"key":"B26","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.meatsci.2005.04.001","article-title":"The science of recalls","volume":"71","author":"Kramer","year":"2005","journal-title":"Meat Sci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"4177","DOI":"10.1128\/JB.184.15.4177-4186.2002","article-title":"Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors","volume":"184","author":"Lauer","year":"2002","journal-title":"J. Bacteriol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1080\/15476286.2016.1189069","article-title":"RNA- and protein-mediated control of Listeria monocytogenes virulence gene expression","volume":"14","author":"Lebreton","year":"2017","journal-title":"RNA Biol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"4418","DOI":"10.1128\/JB.01967-06","article-title":"Flagellar motility is critical for Listeria monocytogenes biofilm formation","volume":"189","author":"Lemon","year":"2007","journal-title":"J. Bacteriol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"3651","DOI":"10.1128\/IAI.00408-09","article-title":"Real-time observation of Listeria monocytogenes-phagocyte interactions in living zebrafish larvae","volume":"77","author":"Levraud","year":"2009","journal-title":"Infect. Immun."},{"key":"B31","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1089\/fpd.2009.0458","article-title":"Reduced host cell invasiveness and oxidative stress tolerance in double and triple csp gene family deletion mutants of Listeria monocytogenes","volume":"7","author":"Loepfe","year":"2010","journal-title":"Foodborne Pathog. Dis."},{"key":"B32","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.ijfoodmicro.2011.05.022","article-title":"Role of flhA and motA in growth of Listeria monocytogenes at low temperatures","volume":"148","author":"Mattila","year":"2011","journal-title":"Int. J. Food Microbiol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.foodres.2014.10.031","article-title":"Listeria monocytogenes in cheese and the dairy environment remains a food safety challenge: the role of stress responses","volume":"67","author":"Melo","year":"2015","journal-title":"Food Res. Internat."},{"key":"B34","doi-asserted-by":"publisher","first-page":"6824","DOI":"10.1073\/pnas.1620772114","article-title":"RNA target profiles direct the discovery of virulence functions for the cold-shock proteins CspC and CspE","volume":"114","author":"Michaux","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B35","doi-asserted-by":"publisher","first-page":"6900","DOI":"10.1128\/JB.01673-12","article-title":"CspR, a cold shock RNA-binding protein involved in the long-term survival and the virulence of Enterococcus faecalis","volume":"194","author":"Michaux","year":"2012","journal-title":"J. Bacteriol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1128\/IAI.00849-15","article-title":"RNA helicase important for Listeria monocytogenes hemolytic activity and virulence factor expression","volume":"84","author":"Netterling","year":"2015","journal-title":"Infect. Immun."},{"key":"B37","doi-asserted-by":"publisher","first-page":"6675","DOI":"10.1128\/IAI.00886-06","article-title":"Listeria monocytogenes flagella are used for motility, not as adhesins, to increase host cell invasion","volume":"74","author":"O'Neil","year":"2006","journal-title":"Infect. Immun."},{"key":"B38","doi-asserted-by":"publisher","first-page":"7007","DOI":"10.1128\/JB.186.20.7007-7014.2004","article-title":"Genome-wide transcriptional analysis of the cold shock response in wild-type and cold-sensitive, quadruple-csp-deletion strains of Escherichia coli","volume":"186","author":"Phadtare","year":"2004","journal-title":"J. Bacteriol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"788","DOI":"10.4161\/rna.7.6.13482","article-title":"RNA remodeling and gene regulation by cold shock proteins","volume":"7","author":"Phadtare","year":"2010","journal-title":"RNA Biol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1084\/jem.167.4.1459","article-title":"Role of hemolysin for the intracellular growth of Listeria monocytogenes","volume":"167","author":"Portnoy","year":"1988","journal-title":"J. Exp. Med."},{"key":"B41","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1111\/j.1462-5822.2008.01213.x","article-title":"A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens","volume":"10","author":"Prajsnar","year":"2008","journal-title":"Cell. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"e1005741","DOI":"10.1371\/journal.ppat.1005741","article-title":"An in vivo selection identifies Listeria monocytogenes genes required to sense the intracellular environment and activate virulence factor expression","volume":"12","author":"Reniere","year":"2016","journal-title":"PLoS Pathog."},{"key":"B43","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/1471-2180-14-154","article-title":"Identification and characterization of an operon, msaABCR, that controls virulence and biofilmdevelopment in Staphylococcus aureus","volume":"14","author":"Sahukhal","year":"2014","journal-title":"BMC Microbiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1089\/fpd.2013.1562","article-title":"Cold shock proteins contribute to the regulation of listeriolysin O production in Listeria monocytogenes","volume":"10","author":"Sch\u00e4rer","year":"2013","journal-title":"Foodborne Pathog. Dis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1128\/AEM.02154-08","article-title":"Role of cold shock proteins in growth of Listeria monocytogenes under cold and osmotic stress conditions","volume":"75","author":"Schmid","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1111\/j.1365-2958.2005.04780.x","article-title":"The 5\u2032 untranslated region-mediated enhancement of intracellular listeriolysin O production is required for Listeria monocytogenes pathogenicity","volume":"57","author":"Shen","year":"2005","journal-title":"Mol. Microbiol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"S396","DOI":"10.1093\/cid\/cis268","article-title":"Invasive listeriosis in the foodborne diseases active surveillance network (FoodNet), 2004-2009: further targeted prevention needed for higher-risk groups","volume":"54","author":"Silk","year":"2012","journal-title":"Clin. Infect. Dis."},{"key":"B48","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1042\/BJ20100557","article-title":"Differentiation of propeptide residues regulating the compartmentalization, maturation and activity of the broad-range phospholipase C of Listeria monocytogenes","volume":"432","author":"Slepkov","year":"2010","journal-title":"Biochem. J."},{"key":"B49","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1089\/fpd.2010.0746","article-title":"The contribution of transcriptomic and proteomic analysis in elucidating stress adaptation responses of Listeria monocytogenes","volume":"8","author":"Soni","year":"2011","journal-title":"Foodborne Pathog. Dis."},{"key":"B50","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1038\/nature08080","article-title":"The Listeria transcriptional landscape from saprophytism to virulence","volume":"459","author":"Toledo-Arana","year":"2009","journal-title":"Nature"},{"key":"B51","doi-asserted-by":"publisher","first-page":"4441","DOI":"10.1128\/AEM.00807-16","article-title":"Response of vibrio cholerae to low-temperature shifts: CspV regulation of type VI secretion, biofilm formation, and association with Zooplankton","volume":"82","author":"Townsley","year":"2016","journal-title":"Appl. Environ. Microbiol"},{"key":"B52","doi-asserted-by":"publisher","first-page":"e1003131","DOI":"10.1371\/journal.ppat.1003131","article-title":"ActA promotes Listeria monocytogenes aggregation, intestinal colonization and carriage","volume":"9","author":"Travier","year":"2013","journal-title":"PLoS Pathog."},{"key":"B53","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1128\/AEM.66.2.860-863.2000","article-title":"Effect of flagella on initial attachment of Listeria monocytogenes to stainless steel","volume":"66","author":"Vatanyoopaisarn","year":"2000","journal-title":"Appl. Environ. Microbiol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1007\/s11427-015-4981-6","article-title":"RNA-seq reveals the critical role of CspA in regulating Brucella melitensis metabolism and virulence","volume":"59","author":"Wang","year":"2016","journal-title":"Sci. China Life Sci."},{"key":"B55","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1128\/AEM.68.2.456-463.2002","article-title":"Enhanced levels of cold shock proteins in Listeria monocytogenes LO28 upon exposure to low temperature and high hydrostatic pressure","volume":"68","author":"Wemekamp-Kamphuis","year":"2002","journal-title":"Appl. Environ. Microbiol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"36023","DOI":"10.1038\/srep36023","article-title":"Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases","volume":"6","author":"Widziolek","year":"2016","journal-title":"Sci. Rep."},{"key":"B57","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1046\/j.1365-2958.2001.02345.x","article-title":"CspD, a novel DNA replication inhibitor induced during the stationary phase in Escherichia coli","volume":"39","author":"Yamanaka","year":"2001","journal-title":"Mol. Microbiol."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00453\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T04:20:14Z","timestamp":1508991614000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00453\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,26]]},"references-count":57,"alternative-id":["10.3389\/fcimb.2017.00453"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2017.00453","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,26]]},"article-number":"453"}}