{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:46:26Z","timestamp":1789904786436,"version":"4.0.1"},"reference-count":51,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI122753"],"award-info":[{"award-number":["AI122753"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM103380"],"award-info":[{"award-number":["GM103380"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI116186"],"award-info":[{"award-number":["AI116186"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2017.00510","type":"journal-article","created":{"date-parts":[[2017,12,11]],"date-time":"2017-12-11T04:32:14Z","timestamp":1512966734000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":25,"title":["Evolution of Bordetellae from Environmental Microbes to Human Respiratory Pathogens: Amoebae as a Missing Link"],"prefix":"10.3389","volume":"7","author":[{"given":"Dawn L.","family":"Taylor-Mulneix","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Illiassou","family":"Hamidou Soumana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodo","family":"Linz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric T.","family":"Harvill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,12,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1128\/AEM.69.1.600-606.2003","article-title":"Survival and growth of Francisella tularensis in Acanthamoeba castellanii","volume":"69","author":"Abd","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/ismej.2015.81","article-title":"Metagenomic resolution of microbial functions in deep-sea hydrothermal plumes across the Eastern Lau Spreading Center","volume":"10","author":"Anantharaman","year":"2016","journal-title":"ISME J."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.1016\/S1473-3099(15)00292-3","article-title":"Emergence of whooping cough: notes from three early epidemics in Persia","volume":"15","author":"Aslanabadi","year":"2015","journal-title":"Lancet Infect. Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"191","DOI":"10.3390\/genes3020191","article-title":"From environment to man: genome evolution and adaptation of human opportunistic bacterial pathogens","volume":"3","author":"Aujoulat","year":"2012","journal-title":"Genes"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e01074","DOI":"10.1128\/mBio.01074-14","article-title":"Global population structure and evolution of Bordetella pertussis and their relationship with vaccination","volume":"5","author":"Bart","year":"2014","journal-title":"MBio"},{"key":"B6","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.idcr.2015.09.004","article-title":"Bordetella petrii recovered from chronic pansinusitis in an adult with cystic fibrosis","volume":"2","author":"Biederman","year":"2015","journal-title":"IDCases"},{"key":"B7","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.mib.2013.06.006","article-title":"Human intestinal metagenomics: state of the art and future","volume":"16","author":"Blottiere","year":"2013","journal-title":"Curr. Opin. Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1007\/s00248-006-9174-1","article-title":"Identification of diazotrophs in the culturable bacterial community associated with roots of Lasiurus sindicus, a perennial grass of thar desert, India","volume":"54","author":"Chowdhury","year":"2007","journal-title":"Microb. Ecol."},{"key":"B9","doi-asserted-by":"crossref","first-page":"3759","DOI":"10.1128\/IAI.65.9.3759-3767.1997","article-title":"Interaction of Mycobacterium avium with environmental amoebae enhances virulence","volume":"65","author":"Cirillo","year":"1997","journal-title":"Infect. Immun."},{"key":"B10","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S0065-2911(01)44013-6","article-title":"Environmental sensing mechanisms in Bordetella","volume":"44","author":"Coote","year":"2001","journal-title":"Adv. Microb. Physiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.mib.2015.05.005","article-title":"Metagenomics of extreme environments","volume":"25","author":"Cowan","year":"2015","journal-title":"Curr. Opin. Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1111\/j.1462-2920.2011.02469.x","article-title":"The Pseudomonas aeruginosa opportunistic pathogen and human infections","volume":"13","author":"de Bentzmann","year":"2011","journal-title":"Environ. Microbiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1371\/journal.ppat.0010045","article-title":"Bordetella pertussis, the causative agent of whooping cough, evolved from a distinct, human-associated lineage of B. bronchiseptica","volume":"1","author":"Diavatopoulos","year":"2005","journal-title":"PLoS Pathog."},{"key":"B14","doi-asserted-by":"publisher","first-page":"E5029","DOI":"10.1073\/pnas.1511878112","article-title":"Burkholderia bacteria infectiously induce the proto-farming symbiosis of Dictyostelium amoebae and food bacteria","volume":"112","author":"DiSalvo","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B15","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.micpath.2014.07.001","article-title":"Looking in amoebae as a source of mycobacteria","volume":"77","author":"Drancourt","year":"2014","journal-title":"Microb. Pathog."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.3201\/eid1107.050046","article-title":"Bordetella petrii clinical isolate","volume":"11","author":"Fry","year":"2005","journal-title":"Emerg. Infect. Dis."},{"key":"B17","doi-asserted-by":"publisher","first-page":"3715","DOI":"10.1099\/mic.0.27432-0","article-title":"Functional characterization of the BvgAS two-component system of Bordetella holmesii","volume":"150","author":"Gerlach","year":"2004","journal-title":"Microbiology"},{"key":"B18","doi-asserted-by":"publisher","first-page":"16127","DOI":"10.1038\/nmicrobiol.2016.127","article-title":"Microbial mercury methylation in Antarctic sea ice","volume":"1","author":"Gionfriddo","year":"2016","journal-title":"Nat. Microbiol."},{"key":"B19","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1128\/MMBR.44.4.722-738.1980","article-title":"Biology of Bordetella bronchiseptica","volume":"44","author":"Goodnow","year":"1980","journal-title":"Microbiol. Rev."},{"key":"B20","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1128\/CMR.17.2.413-433.2004","article-title":"Microorganisms resistant to free-living amoebae","volume":"17","author":"Greub","year":"2004","journal-title":"Clin. Microbiol. Rev."},{"key":"B21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s00430-010-0148-z","article-title":"Resemblance and divergence: the \u201cnew\u201d members of the genus Bordetella","volume":"199","author":"Gross","year":"2010","journal-title":"Med. Microbiol. Immunol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1046\/j.1462-5822.2000.00044.x","article-title":"Dictyostelium discoideum: a new host model system for intracellular pathogens of the genus Legionella","volume":"2","author":"H\u00e4gele","year":"2000","journal-title":"Cell. Microbiol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3389\/fmicb.2017.00028","article-title":"Environmental origin of the genus Bordetella","volume":"8","author":"Hamidou Soumana","year":"2017","journal-title":"Front. Microbiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"5452","DOI":"10.1099\/ijsem.0.001540","article-title":"Identification and taxonomic characterization of Bordetella pseudohinzii sp. nov. isolated from laboratory-raised mice","volume":"66","author":"Ivanov","year":"2016","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1186\/s12864-015-2028-9","article-title":"A newly discovered Bordetella species carries a transcriptionally active CRISPR-Cas with a small Cas9 endonuclease","volume":"16","author":"Ivanov","year":"2015","journal-title":"BMC Genomics"},{"key":"B26","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1590\/S0036-46652015000100012","article-title":"Identification of Pseudomonas spp. as amoeba-resistant microorganisms in isolates of Acanthamoeba","volume":"57","author":"Jose Maschio","year":"2015","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"B27","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1099\/00207713-34-1-56","article-title":"Bordetella avium sp. nov., isolated from the respiratory tracts of turkeys and other birds","volume":"34","author":"Kersters","year":"1984","journal-title":"Int. J. Syst. Bacteriol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"2516","DOI":"10.1128\/JCM.43.5.2516-2519.2005","article-title":"New species of Bordetella, Bordetella ansorpii sp. nov., isolated from the purulent exudate of an epidermal cyst","volume":"43","author":"Ko","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1111\/2049-632X.12072","article-title":"Bordetella pertussis entry into respiratory epithelial cells and intracellular survival","volume":"69","author":"Lamberti","year":"2013","journal-title":"Pathog. Dis."},{"key":"B30","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1128\/IAI.01031-09","article-title":"Intracellular trafficking of Bordetella pertussis in human macrophages","volume":"78","author":"Lamberti","year":"2010","journal-title":"Infect. Immun."},{"key":"B31","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1186\/s12864-016-3112-5","article-title":"Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species","volume":"17","author":"Linz","year":"2016","journal-title":"BMC Genomics"},{"key":"B32","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.copbio.2016.01.011","article-title":"Microbial diversity and functional capacity in polar soils","volume":"38","author":"Makhalanyane","year":"2016","journal-title":"Curr. Opin. Biotechnol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1128\/CMR.18.2.326-382.2005","article-title":"Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies","volume":"18","author":"Mattoo","year":"2005","journal-title":"Clin. Microbiol. Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1128\/IAI.68.4.2024-2033.2000","article-title":"Role of Bordetella bronchiseptica fimbriae in tracheal colonization and development of a humoral immune response","volume":"68","author":"Mattoo","year":"2000","journal-title":"Infect. Immun."},{"key":"B35","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1128\/JB.180.7.1682-1690.1998","article-title":"Characterization of the bvgR locus of Bordetella pertussis","volume":"180","author":"Merkel","year":"1998","journal-title":"J. Bacteriol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1128\/AEM.71.1.20-28.2005","article-title":"Amoebae as training grounds for intracellular bacterial pathogens","volume":"71","author":"Molmeret","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1097\/INF.0000000000000564","article-title":"Bordetella petrii sinusitis in an immunocompromised adolescent","volume":"34","author":"Nagata","year":"2015","journal-title":"Pediatr. Infect. Dis. J."},{"key":"B38","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3382\/ps.0600107","article-title":"Bacterial coryza in turkeys in Texas","volume":"60","author":"Panigrahy","year":"1981","journal-title":"Poult. Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1186\/1471-2164-13-545","article-title":"Comparative genomics of the classical Bordetella subspecies: the evolution and exchange of virulence-associated diversity amongst closely related pathogens","volume":"13","author":"Park","year":"2012","journal-title":"BMC Genomics"},{"key":"B40","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1038\/ng1227","article-title":"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica","volume":"35","author":"Parkhill","year":"2003","journal-title":"Nat. Genet."},{"key":"B41","doi-asserted-by":"publisher","first-page":"40","DOI":"10.7589\/0090-3558-38.1.40","article-title":"Prevalence of Bordetella avium infection in selected wild and domesticated birds in the eastern USA","volume":"38","author":"Raffel","year":"2002","journal-title":"J. Wildl. Dis."},{"key":"B42","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/nmeth1156","article-title":"Next-generation sequencing transforms today's biology","volume":"5","author":"Schuster","year":"2008","journal-title":"Nat. Methods"},{"key":"B43","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.syapm.2004.12.002","article-title":"A molecular systematic survey of cultured microbial associates of deep-water marine invertebrates","volume":"28","author":"Sfanos","year":"2005","journal-title":"Syst. Appl. Microbiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"7131","DOI":"10.4049\/jimmunol.177.10.7131","article-title":"Bordetella bronchiseptica modulates macrophage phenotype leading to the inhibition of CD4+ T cell proliferation and the initiation of a Th17 immune response","volume":"177","author":"Siciliano","year":"2006","journal-title":"J. Immunol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e2000420","DOI":"10.1371\/journal.pbio.2000420","article-title":"Bordetella bronchiseptica exploits the complex life cycle of Dictyostelium discoideum as an amplifying transmission vector","volume":"15","author":"Taylor-Mulneix","year":"2017","journal-title":"PLoS Biol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"4830","DOI":"10.1099\/ijsem.0.000655","article-title":"Novel environmental species isolated from the plaster wall surface of mural paintings in the Takamatsuzuka tumulus: Bordetella muralis sp. nov., Bordetella tumulicola sp. nov. and Bordetella tumbae sp. nov","volume":"65","author":"Tazato","year":"2015","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B47","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1099\/00207713-46-4-849","article-title":"Bordetella trematum sp. nov., isolated from wounds and ear infections in humans, and reassessment of Alcaligenes denitrificans Ruger and Tan 1983","volume":"46","author":"Vandamme","year":"1996","journal-title":"Int. J. Syst. Bacteriol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1099\/00207713-45-1-37","article-title":"Bordetella hinzii sp. nov., isolated from poultry and humans","volume":"45","author":"Vandamme","year":"1995","journal-title":"Int. J. Syst. Bacteriol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"3674","DOI":"10.1099\/ijsem.0.000473","article-title":"Bordetella bronchialis sp. nov., Bordetella flabilis sp. nov. and Bordetella sputigena sp. nov., isolated from human respiratory specimens, and reclassification of Achromobacter sediminum Zhang et al. 2014 as Verticia sediminum gen. nov., comb. nov","volume":"65","author":"Vandamme","year":"2015","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1099\/00207713-51-4-1257","article-title":"Bordetella petrii sp. nov., isolated from an anaerobic bioreactor, and emended description of the genus Bordetella","volume":"51","author":"von Wintzingerode","year":"2001","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/JCM.33.1.1-7.1995","article-title":"Bordetella holmesii sp, nov., a new Gram-negative species associated with septicemia","volume":"33","author":"Weyant","year":"1995","journal-title":"J. Clin. Microbiol."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00510\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,24]],"date-time":"2020-10-24T03:04:51Z","timestamp":1603508691000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2017.00510\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,11]]},"references-count":51,"alternative-id":["10.3389\/fcimb.2017.00510"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2017.00510","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,11]]},"article-number":"510"}}