{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:54:01Z","timestamp":1753890841568,"version":"3.41.2"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,3,19]],"date-time":"2018-03-19T00:00:00Z","timestamp":1521417600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1081167","1012386","1079904"],"award-info":[{"award-number":["1081167","1012386","1079904"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["140100594"],"award-info":[{"award-number":["140100594"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2018.00087","type":"journal-article","created":{"date-parts":[[2018,3,19]],"date-time":"2018-03-19T04:19:00Z","timestamp":1521433140000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["The Use of CRISPR\/Cas9 Gene Editing to Confirm Congenic Contaminations in Host-Pathogen Interaction Studies"],"prefix":"10.3389","volume":"8","author":[{"given":"Jonathan","family":"Ferrand","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan P.","family":"Croft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevi\u00e8ve","family":"P\u00e9pin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerrilyn R.","family":"Diener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niamh E.","family":"Mangan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Behlke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Hayball","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony W.","family":"Purcell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard L.","family":"Ferrero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Gantier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2018,3,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1126\/science.1231143","article-title":"Multiplex genome engineering using CRISPR\/Cas systems","volume":"339","author":"Cong","year":"2013","journal-title":"Science"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2513","DOI":"10.1074\/mcp.M113.031591","article-title":"Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ","volume":"13","author":"Cox","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1038\/nbt.1511","article-title":"MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification","volume":"26","author":"Cox","year":"2008","journal-title":"Nat. Biotechnol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.bbi.2008.09.001","article-title":"Cautionary insights on knockout mouse studies: the gene or not the gene?","volume":"23","author":"Eisener-Dorman","year":"2009","journal-title":"Brain Behav. Immun."},{"key":"B5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/978-1-4939-3335-8_5","article-title":"Assessing the inhibitory activity of oligonucleotides on TLR7 sensing","volume":"1390","author":"Ferrand","year":"2016","journal-title":"Methods Mol. Biol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"D1049","DOI":"10.1093\/nar\/gku1179","article-title":"Gene ontology consortium: going forward","volume":"43","author":"Gene Ontology","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1042\/bj3540511","article-title":"Natural-resistance-associated macrophage protein 1 is an H+\/bivalent cation antiporter","volume":"354","author":"Goswami","year":"2001","journal-title":"Biochem. J."},{"key":"B8","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1128\/IAI.67.5.2225-2232.1999","article-title":"Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7","volume":"67","author":"Govoni","year":"1999","journal-title":"Infect. Immun."},{"key":"B9","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1002\/eji.201142048","article-title":"The need for littermate controls","volume":"42","author":"Holmdahl","year":"2012","journal-title":"Eur. J. Immunol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1126\/science.1225829","article-title":"A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity","volume":"337","author":"Jinek","year":"2012","journal-title":"Science"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e00471","DOI":"10.7554\/eLife.00471","article-title":"RNA-programmed genome editing in human cells","volume":"2","author":"Jinek","year":"2013","journal-title":"Elife"},{"key":"B12","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1038\/nature10558","article-title":"Non-canonical inflammasome activation targets caspase-11","volume":"479","author":"Kayagaki","year":"2011","journal-title":"Nature"},{"key":"B13","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1038\/nrmicro3428","article-title":"Now you see me, now you don't: the interaction of Salmonella with innate immune receptors","volume":"13","author":"Keestra-Gounder","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e111763","DOI":"10.1371\/journal.pone.0111763","article-title":"Temporal and anatomical host resistance to chronic Salmonella infection is quantitatively dictated by Nramp1 and influenced by host genetic background","volume":"9","author":"Loomis","year":"2014","journal-title":"PLoS ONE"},{"key":"B15","doi-asserted-by":"publisher","first-page":"5598","DOI":"10.1073\/pnas.0400937101","article-title":"Recognition of single-stranded RNA viruses by Toll-like receptor 7","volume":"101","author":"Lund","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B16","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1084\/jem.20031319","article-title":"Salmonella typhimurium persists within macrophages in the mesenteric lymph nodes of chronically infected Nramp1+\/+ mice and can be reactivated by IFNgamma neutralization","volume":"199","author":"Monack","year":"2004","journal-title":"J. Exp. Med."},{"key":"B17","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1038\/287440a0","article-title":"Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci","volume":"287","author":"O'brien","year":"1980","journal-title":"Nature"},{"key":"B18","doi-asserted-by":"publisher","first-page":"5356","DOI":"10.1093\/nar\/gkw405","article-title":"Cre-dependent DNA recombination activates a STING-dependent innate immune response","volume":"44","author":"P\u00e9pin","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"B19","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0008-8749(88)90236-5","article-title":"Immortalization of cloned mouse splenic macrophages with a retrovirus containing the v-raf\/mil and v-myc oncogenes","volume":"116","author":"Roberson","year":"1988","journal-title":"Cell Immunol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1038\/ni.2397","article-title":"Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium","volume":"13","author":"Robinson","year":"2012","journal-title":"Nat. Immunol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/nmeth.4293","article-title":"Unexpected mutations after CRISPR-Cas9 editing in vivo","volume":"14","author":"Schaefer","year":"2017","journal-title":"Nat. Methods"},{"key":"B22","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"key":"B23","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.immuni.2015.06.011","article-title":"Passenger mutations confound interpretation of all genetically modified congenic mice","volume":"43","author":"Vanden Berghe","year":"2015","journal-title":"Immunity"},{"key":"B24","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/0092-8674(93)90135-D","article-title":"Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg","volume":"73","author":"Vidal","year":"1993","journal-title":"Cell"},{"key":"B25","doi-asserted-by":"crossref","first-page":"3559","DOI":"10.4049\/jimmunol.157.8.3559","article-title":"Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains","volume":"157","author":"Vidal","year":"1996","journal-title":"J. Immunol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"D447","DOI":"10.1093\/nar\/gkw880","article-title":"2016 update of the PRIDE database and its related tools","volume":"44","author":"Vizcaino","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"B27","doi-asserted-by":"publisher","first-page":"6013","DOI":"10.4049\/jimmunol.1002129","article-title":"Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion","volume":"185","author":"Wei","year":"2010","journal-title":"J. Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1038\/nmeth.1322","article-title":"Universal sample preparation method for proteome analysis","volume":"6","author":"Wi\u015bniewski","year":"2009","journal-title":"Nat. Methods"},{"key":"B29","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1073\/pnas.1317643111","article-title":"Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection","volume":"111","author":"Zaki","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2018.00087\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T17:34:23Z","timestamp":1693589663000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2018.00087\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,19]]},"references-count":29,"alternative-id":["10.3389\/fcimb.2018.00087"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2018.00087","relation":{},"ISSN":["2235-2988"],"issn-type":[{"type":"electronic","value":"2235-2988"}],"subject":[],"published":{"date-parts":[[2018,3,19]]},"article-number":"87"}}