{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:11:24Z","timestamp":1787026284211,"version":"build-2736575974"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2018.00125","type":"journal-article","created":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T09:03:48Z","timestamp":1525165428000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["Shiga Toxin-Producing Escherichia coli Infection in J\u00f6nk\u00f6ping County, Sweden: Occurrence and Molecular Characteristics in Correlation With Clinical Symptoms and Duration of stx Shedding"],"prefix":"10.3389","volume":"8","author":[{"given":"Xiangning","family":"Bai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mernelius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Jernberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ing-Marie","family":"Einemo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Monecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Ehricht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sture","family":"L\u00f6fgren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Matussek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,5,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3389\/fcimb.2016.00143","article-title":"Molecular and phylogenetic characterization of non-O157 shiga toxin-producing Escherichia coli strains in China","volume":"6","author":"Bai","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1128\/JCM.39.1.370-374.2001","article-title":"Rapid detection of enterohemorrhagic Escherichia coli by real-time PCR with fluorescent hybridization probes","volume":"39","author":"Bellin","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/S1473-3099(11)70165-7","article-title":"Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study","volume":"11","author":"Bielaszewska","year":"2011","journal-title":"Lancet Infect. Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.cll.2015.02.004","article-title":"Shiga toxin producing Escherichia coli","volume":"35","author":"Bryan","year":"2015","journal-title":"Clin. Lab. Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1128\/JCM.03590-14","article-title":"Assessing the public health risk of Shiga toxin-producing Escherichia coli by use of a rapid diagnostic screening algorithm","volume":"53","author":"de Boer","year":"2015","journal-title":"J. Clin. Microbiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"6115","DOI":"10.1128\/IAI.68.11.6115-6126.2000","article-title":"The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli","volume":"68","author":"Elliott","year":"2000","journal-title":"Infect. Immun."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1128\/IAI.01182-10","article-title":"Shiga toxin subtypes display dramatic differences in potency","volume":"79","author":"Fuller","year":"2011","journal-title":"Infect. Immun."},{"key":"B8","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1111\/1348-0421.12120","article-title":"Rapid microarray-based DNA genoserotyping of Escherichia coli","volume":"58","author":"Geue","year":"","journal-title":"Microbiol. Immunol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1128\/JCM.01048-14","article-title":"Development of a rapid microarray-based DNA subtyping assay for the alleles of Shiga toxins 1 and 2 of Escherichia coli","volume":"52","author":"Geue","year":"","journal-title":"J. Clin. Microbiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"e63027","DOI":"10.1371\/journal.pone.0063027","article-title":"Adaptive mutations and replacements of virulence traits in the Escherichia coli O104:H4 outbreak population","volume":"8","author":"Guy","year":"2013","journal-title":"PLoS ONE"},{"key":"B11","doi-asserted-by":"publisher","first-page":"E3627","DOI":"10.1073\/pnas.1206246110","article-title":"Genomic diversity of the 2011 European outbreaks of Escherichia coli O104:H4","volume":"109","author":"Guy","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B12","doi-asserted-by":"publisher","first-page":"3156","DOI":"10.1128\/JCM.00453-14","article-title":"PCR-based detection and molecular characterization of shiga toxin-producing Escherichia coli strains in a routine microbiology laboratory over 16 years","volume":"52","author":"Haugum","year":"2014","journal-title":"J. Clin. Microbiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s10096-007-0420-3","article-title":"Relationship between pathogenicity for humans and stx genotype in Shiga toxin-producing Escherichia coli serotype O157","volume":"27","author":"Kawano","year":"2008","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B14","doi-asserted-by":"publisher","first-page":"766","DOI":"10.3389\/fmicb.2016.00766","article-title":"Implementation of Whole Genome Sequencing (WGS) for identification and characterization of shiga toxin-producing Escherichia coli (STEC) in the United States","volume":"7","author":"Lindsey","year":"2016","journal-title":"Front. Microbiol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1093\/jpids\/piv003","article-title":"Shiga toxin-producing Escherichia coli in diarrheal stool of swedish children: evaluation of polymerase chain reaction screening and duration of shiga toxin shedding","volume":"5","author":"Matussek","year":"2016","journal-title":"J. Pediatric Infect. Dis. Soc."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.3201\/eid1408.071082","article-title":"Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli","volume":"14","author":"Mellmann","year":"2008","journal-title":"Emerging Infect. Dis."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.1007\/s10096-017-2974-z","article-title":"Virulence factors of Shiga toxin-producing Escherichia coli and the risk of developing haemolytic uraemic syndrome in Norway, 1992\u20132013","volume":"36","author":"Naseer","year":"2017","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B18","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1128\/microbiolspec.EHEC-0008-2013","article-title":"Escherichia coli O104:H4 pathogenesis: an enteroaggregative, E. coli\/shiga toxin-producing, E. coli explosive cocktail of high virulence","author":"Navarro-Garcia","year":"2014","journal-title":"Microbiol. Spectr"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.12789","article-title":"Enterohaemorrhagic and other Shiga toxin-producing Escherichia coli (STEC): Where are we now regarding diagnostics and control strategies?","author":"Newell","year":"2018","journal-title":"Transbound. Emerg. Dis"},{"key":"B20","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.diagmicrobio.2007.04.013","article-title":"The Shiga toxin genotype rather than the amount of Shiga toxin or the cytotoxicity of Shiga toxin in vitro correlates with the appearance of the hemolytic uremic syndrome","volume":"59","author":"Orth","year":"2007","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"B21","doi-asserted-by":"publisher","first-page":"478","DOI":"10.3389\/fmicb.2016.00478","article-title":"Detection, characterization, and typing of shiga toxin-producing Escherichia coli","volume":"7","author":"Parsons","year":"2016","journal-title":"Front. Microbiol."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.10.002","article-title":"Shiga toxin-producing Escherichia coli: incidence and clinical features in a setting with complete screening of patients with suspected infective diarrhoea","author":"Pedersen","year":"2017","journal-title":"Clin. Microbiol. Infect"},{"key":"B23","unstructured":"New Procedures for Contraceptive Measures in EHEC Infection\n            Peter NolskogB. S.\n            CeciliaJernberg\n          pdf. Medical Comment. L\u00e4kartidningen2017"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.EHEC-0020-2013","article-title":"EHEC genomics: past, present, and future","author":"Sadiq","year":"2014","journal-title":"Microbiol. Spectr."},{"key":"B25","doi-asserted-by":"publisher","first-page":"2951","DOI":"10.1128\/JCM.00860-12","article-title":"Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature","volume":"50","author":"Scheutz","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1089\/fpd.2007.0065","article-title":"A large Escherichia coli O157 outbreak in Sweden associated with locally produced lettuce","volume":"5","author":"S\u00f6derstr\u00f6m","year":"2008","journal-title":"Foodborne Pathog. Dis."},{"key":"B27","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1086\/313770","article-title":"Enteropathogens in adult patients with diarrhea and healthy control subjects: a 1-year prospective study in a Swedish clinic for infectious diseases","volume":"30","author":"Svenungsson","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/S0140-6736(05)71144-2","article-title":"Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome","volume":"365","author":"Tarr","year":"2005","journal-title":"Lancet"},{"key":"B29","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1136\/jclinpath-2016-203882","article-title":"Prevalence of Shiga toxin-producing and enteropathogenic Escherichia coli marker genes in diarrhoeic stools in a New Zealand catchment area","volume":"70","author":"Thomas","year":"2017","journal-title":"J. Clin. Pathol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.3201\/eid2310.161836","article-title":"Mild illness during outbreak of shiga toxin-producing Escherichia coli O157 infections associated with agricultural show, Australia","volume":"23","author":"Vasant","year":"2017","journal-title":"Emerging Infect. Dis."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2018.00125\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T09:03:50Z","timestamp":1525165430000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fcimb.2018.00125\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,1]]},"references-count":30,"alternative-id":["10.3389\/fcimb.2018.00125"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2018.00125","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,1]]},"article-number":"125"}}