{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:48:16Z","timestamp":1777416496965,"version":"3.51.4"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2019.00230","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T04:17:15Z","timestamp":1561522635000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Serial Systemic Candida albicans Infection Highlighted by Proteomics"],"prefix":"10.3389","volume":"9","author":[{"given":"Glaucia Sayuri","family":"Arita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Eduardo","family":"Meneguello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina Mayumi","family":"Sakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniella Renata","family":"Faria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Jorge","family":"Pilau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana Dias","family":"Ghiraldi-Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula Aline Zanetti","family":"Campanerut-S\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9rika Seki","family":"Kioshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia de Souza","family":"Bonfim-Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terezinha Inez Estivalet","family":"Svidzinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.jprot.2013.07.031","article-title":"Elucidation of potentially virulent factors of Candida albicans during serum adaptation by using quantitative time-course proteomics","volume":"91","author":"Aoki","year":"","journal-title":"J. Proteomics"},{"key":"B2","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/2049-632X.12003","article-title":"Time-course proteomic profile of Candida albicans during adaptation to a fetal serum","volume":"67","author":"Aoki","year":"","journal-title":"Pathog. Dis"},{"key":"B3","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0966-842X(01)02094-7","article-title":"Virulence factors of Candida albicans","volume":"9","author":"Calderone","year":"2001","journal-title":"Trends Microbiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1038\/nbt.2377","article-title":"A Cross-platform toolkit for mass spectrometry and proteomics","volume":"30","author":"Chambers","year":"2012","journal-title":"Nat. Biotechnol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/nrmicro1426","article-title":"Signalling and oxidant adaptation in Candida albicans and Aspergillus fumigatus","volume":"4","author":"Chauhan","year":"2006","journal-title":"Nat. Rev. Microbiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1111\/j.1462-5822.2006.00805.x","article-title":"Uncoupling of oxidative phosphorylation enables Candida albicans to resist killing by phagocytes and persist in tissue","volume":"9","author":"Cheng","year":"2007","journal-title":"Cell. Microbiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1128\/EC.00107-12","article-title":"Investigating the function of Ddr48p in Candida albicans","volume":"11","author":"Cleary","year":"2012","journal-title":"Eukaryot. Cell"},{"key":"B8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.3390\/pathogens4030573","article-title":"Coordination of Candida albicans invasion and infection functions by phosphoglycerol phosphatase Rhr2","volume":"4","author":"Desai","year":"2015","journal-title":"Pathogens"},{"key":"B9","first-page":"BR113","article-title":"The Candida albicans Ddr48 protein is essential for filamentation, stress response, and confers partial antifungal drug resistance","volume":"14","author":"Dib","year":"2008","journal-title":"Med. Sci. Monit."},{"key":"B10","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1590\/S1678-9946201658025","article-title":"Candida albicans protein profile changes in response to the butanolic extract of Sapindus saponaria L","volume":"58","author":"Fiorini","year":"2016","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"B11","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1128\/EC.3.2.536-545.2004","article-title":"Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns","volume":"3","author":"G\u00e1rcia-S\u00e1nchez","year":"2004","journal-title":"Eukaryot. Cell"},{"key":"B12","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/S1369-5274(02)00338-7","article-title":"Fungal morphogenesis and host invasion","volume":"5","author":"Gow","year":"2002","journal-title":"Curr Opin Microbiol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1099\/mic.0.27663-0","article-title":"Yeast wall protein 1 of Candida albicans","volume":"151","author":"Granger","year":"2005","journal-title":"Microbiology"},{"key":"B14","doi-asserted-by":"publisher","first-page":"4814","DOI":"10.1091\/mbc.e05-05-0435","article-title":"Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence","volume":"16","author":"Hromatka","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"B15","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.cub.2009.01.018","article-title":"CO2 regulates white-to-opaque switching in Candida albicans","volume":"19","author":"Huang","year":"2009","journal-title":"Curr. Biol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.mib.2004.06.003","article-title":"From commensal to pathogen: stage- and tissue-specific gene expression of Candida albicans","volume":"7","author":"Hube","year":"2004","journal-title":"Curr. Opin. Microbiol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"i4","DOI":"10.1093\/jac\/dkx444","article-title":"Changes in the epidemiological landscape of invasive candidiasis","volume":"73","author":"Lamoth","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"B18","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1038\/msb.2011.48","article-title":"A dynamic model of proteome changes reveals new roles for transcript alteration in yeast","volume":"7","author":"Lee","year":"2011","journal-title":"Mol. Syst. Biol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"E5336","DOI":"10.1073\/pnas.1513447112","article-title":"Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase","volume":"112","author":"Li","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B20","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/S0092-8674(00)80358-X","article-title":"Nonfilamentous C","volume":"90","author":"Lo","year":"1997","journal-title":"albicans mutants are avirulent. Cell"},{"key":"B21","doi-asserted-by":"publisher","first-page":"e64482","DOI":"10.1371\/journal.pone.0064482","article-title":"Serial passaging of Candida albicans in systemic murine infection suggests that the wild type strain SC5314 is well adapted to the murine kidney","volume":"8","author":"L\u00fcttich","year":"2013","journal-title":"PLoS ONE"},{"key":"B22","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.femsle.2005.02.014","article-title":"DNA array analysis of Candida albicans gene expression in response to adherence to polystyrene","volume":"245","author":"Marchais","year":"2005","journal-title":"FEMS Microbiology Lett."},{"key":"B23","doi-asserted-by":"publisher","first-page":"D442","DOI":"10.1093\/nar\/gky1106","article-title":"The PRIDE database and related tools and resources in 2019: improving support for quantification data","volume":"47","author":"Perez-Riverol","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"B24","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1128\/CMR.00029-06","article-title":"Epidemiology of invasive candidiasis: a persistent public health problem","volume":"20","author":"Pfaller","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1007\/s00580-011-1325-1","article-title":"The early response of Candida albicans filament induction is coupled with wholesale expression of the translation machinery","volume":"21","author":"Rashki","year":"2012","journal-title":"Comp. Clin. Path."},{"key":"B26","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.micpath.2017.10.044","article-title":"Healthcare workers' hands as a vehicle for the transmission of virulent strains of Candida spp.: a virulence factor approach","volume":"113","author":"Sakita","year":"2017","journal-title":"Microb. Pathog."},{"key":"B27","doi-asserted-by":"publisher","first-page":"e1003210","DOI":"10.1371\/journal.ppat.1003210","article-title":"Candida albicans white and opaque cells undergo distinct programs of filamentous growth","volume":"9","author":"Si","year":"2013","journal-title":"PLoS Pathog"},{"key":"B28","doi-asserted-by":"publisher","first-page":"5795","DOI":"10.1002\/pmic.200600332","article-title":"Proteomics for the analysis of the Candida albicans biofilm lifestyle","volume":"6","author":"Thomas","year":"2006","journal-title":"Proteomics"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1002\/pmic.201400449","article-title":"Visualization of LC-MS\/MS proteomics data in MaxQuant","volume":"15","author":"Tyanova","year":"2015","journal-title":"Proteomics"},{"key":"B30","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"key":"B31","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1128\/.61.2.170-192.1997","article-title":"Macrophages in resistance to candidiasis","volume":"61","author":"V\u00e1zquez-Torres","year":"1997","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B32","doi-asserted-by":"publisher","first-page":"599","DOI":"10.3724\/SP.J.1008.2010.00599","article-title":"Overexpression of IFD6 in Candida albicans promotes biofilm formation","volume":"31","author":"Ying","year":"2010","journal-title":"Acad. J. Second Military Med. Univer."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2019.00230\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T23:03:23Z","timestamp":1610060603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2019.00230\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,26]]},"references-count":32,"alternative-id":["10.3389\/fcimb.2019.00230"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2019.00230","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,26]]},"article-number":"230"}}