{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:53:28Z","timestamp":1792446808353,"version":"4.5.0"},"reference-count":95,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011019","name":"Nemzeti Kutat\u00e1si Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011019","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003825","name":"Magyar Tudom\u00e1nyos Akad\u00e9mia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2020.00094","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T04:26:27Z","timestamp":1583987187000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":92,"title":["Mechanisms of Pathogenic Candida Species to Evade the Host Complement Attack"],"prefix":"10.3389","volume":"10","author":[{"given":"Dhirendra Kumar","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e1ta","family":"T\u00f3th","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"G\u00e1cser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,3,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1371\/journal.ppat.1002793","article-title":"The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection","volume":"8","author":"Ali","year":"2012","journal-title":"PLoS Pathog."},{"key":"B2","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1111\/tid.12613","article-title":"The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the transplant-associated infection surveillance network (TRANSNET)","volume":"18","author":"Andes","year":"2016","journal-title":"Transpl. Infect. Dis."},{"key":"B3","doi-asserted-by":"publisher","first-page":"7045630","DOI":"10.1155\/2017\/7045630","article-title":"Mannose-binding lectin: biologic characteristics and role in the susceptibility to infections and ischemia-reperfusion related injury in critically ill neonates","volume":"2017","author":"Auriti","year":"2017","journal-title":"J. Immunol. Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"844","DOI":"10.3389\/fmicb.2017.00844","article-title":"Direct binding of the pH-regulated protein 1 (Pra1) from Candida albicans inhibits cytokine secretion by mouse CD 4+ T Cells","volume":"8","author":"Bergfeld","year":"2017","journal-title":"Front. Microbiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e57","DOI":"10.3390\/jof3040057","article-title":"Global and multi-national prevalence of fungal diseases\u2014estimate precision","volume":"3","author":"Bongomin","year":"2017","journal-title":"J. Fungi."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1128\/IAI.00744-09","article-title":"Influence of mannan and glucan on complement activation and C3 binding by Candida albicans","volume":"78","author":"Boxx","year":"2010","journal-title":"Infect. Immun."},{"key":"B7","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.immuni.2012.08.002","article-title":"Regulation of humoral immunity by complement","volume":"37","author":"Carroll","year":"2012","journal-title":"Immunity"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1093\/jac\/dkx047","article-title":"Changing epidemiology of candidaemia in Australia","volume":"72","author":"Chapman","year":"2017","journal-title":"J. Antimicrob. Chemother."},{"key":"B9","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1002\/eji.201142057","article-title":"Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs","volume":"42","author":"Cheng","year":"2012","journal-title":"Eur. J. Immunol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1016\/j.it.2019.11.001","article-title":"Kupffer cells mediate systemic antifungal immunit","volume":"40","author":"Coelho","year":"2019","journal-title":"Trends Immunol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/BF00158569","article-title":"The secretion of aspartyl proteinase, a virulence enzyme, by isolates of Candida albicans from the oral cavity of HIV-infected subjects","volume":"3","author":"De Bernardis","year":"1992","journal-title":"Eur. J. Epidemiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1128\/IAI.64.2.466-471.1996","article-title":"Elevated aspartic proteinase secretion and experimental pathogenicity of Candida albicans isolates from oral cavities of subjects infected with human immunodeficiency virus","volume":"2","author":"De Bernardis","year":"1996","journal-title":"Infect. Immun"},{"key":"B13","doi-asserted-by":"publisher","first-page":"3481","DOI":"10.1128\/JCM.37.11.3481-3486.1999","article-title":"Biotyping and virulence properties of skin isolates of Candida parapsilosis","volume":"11","author":"De Bernardis","year":"1999","journal-title":"J. Clin. Microbiol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1038\/s41423-018-0024-0","article-title":"NETosis, complement, and coagulation: a triangular relationship","volume":"16","author":"de Bont","year":"2018","journal-title":"Cell Mol. Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/cr.2009.139","article-title":"Complement and its role in innate and adaptive immune responses","volume":"20","author":"Dunkelberger","year":"2009","journal-title":"Cell Res."},{"key":"B16","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.4049\/jimmunol.137.11.3577","article-title":"Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors","volume":"137","author":"Edwards","year":"1986","journal-title":"J. Immunol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1038\/nri800","article-title":"Evolution of the lectin - complement pathway and its role in innate immunity","volume":"2","author":"Fujita","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1128\/IAI.22.3.861-866.1978","article-title":"Proteolytic activity of Candida albicans : action on human salivary proteins","volume":"22","author":"Germaine","year":"1978","journal-title":"Infect. Immun"},{"key":"B19","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/j.molimm.2009.08.019","article-title":"The yeast Candida albicans evades human complement attack by secretion of aspartic proteases","volume":"47","author":"Gropp","year":"2009","journal-title":"Mol. Immunol."},{"key":"B20","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1172\/JCI115214","article-title":"Molecular mimicry in Candida albicans. Role of an integrin analogue in adhesion of the yeast to human endothelium","volume":"87","author":"Gustafson","year":"1991","journal-title":"J Clin Invest"},{"key":"B21","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1006\/fgbi.1999.1165","article-title":"Integrin-like proteins in Candida spp and other microorganisms","volume":"28","author":"Hostetter","year":"1999","journal-title":"Fungal Genet. Biol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.vaccine.2008.11.056","article-title":"The iC3b receptor of Candida albicans and its roles in pathogenesis","volume":"26","author":"Hostetter","year":"2008","journal-title":"Vaccine"},{"key":"B23","doi-asserted-by":"publisher","first-page":"e1004985","DOI":"10.1371\/journal.ppat.1004985","article-title":"CR3 and Dectin-1 collaborate in macrophage cytokine response through association on lipid rafts and activation of Syk-JNK-AP-1 pathway","volume":"11","author":"Huang","year":"2015","journal-title":"PLoS Pathog."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.4049\/jimmunol.1401845","article-title":"A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a","volume":"194","author":"H\u00fcnniger","year":"2015","journal-title":"J. Immunol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1086\/422397","article-title":"Role of mannose-binding lectin in the innate defense against Candida albicans: enhancement of complement activation, but lack of opsonic function, in phagocytosis by human dendritic cells","volume":"190","author":"Ip","year":"2004","journal-title":"J. Infect. Dis."},{"key":"B26","doi-asserted-by":"publisher","first-page":"2139","DOI":"10.1128\/IAI.58.7.2139-2143.1990","article-title":"Activation of the plasma kallikrein-kinin system by Candida albicans proteinase","volume":"58","author":"Kaminishi","year":"1990","journal-title":"Infect. Immun."},{"key":"B27","doi-asserted-by":"publisher","first-page":"E41","DOI":"10.3390\/jof3030041","article-title":"Strategies to reduce mortality in adult and neonatal candidemia in developing countries","volume":"3","author":"Kaur","year":"2017","journal-title":"J. Fungi."},{"key":"B28","doi-asserted-by":"publisher","first-page":"3319","DOI":"10.3389\/fmicb.2018.03319","article-title":"Candida albicans factor H binding molecule Hgt1p - a low glucose-induced transmembrane protein is trafficked to the cell wall and impairs phagocytosis and killing by human neutrophils","volume":"9","author":"Kenno","year":"2019","journal-title":"Front. Microbiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s00281-017-0644-y","article-title":"Complement as a regulator of adaptive immunity","volume":"40","author":"Killick","year":"2017","journal-title":"Semin. Immunopathol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1128\/CMR.9.1.34","article-title":"Activation of the complement system by pathogenic fungi","volume":"9","author":"Kozel","year":"1996","journal-title":"Clin. Microbiol. Rev."},{"key":"B31","doi-asserted-by":"publisher","first-page":"i4","DOI":"10.1093\/jac\/dkx444","article-title":"Changes in the epidemiological landscape of invasive candidiasis","volume":"73","author":"Lamoth","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"B32","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1016\/j.ajic.2018.05.015","article-title":"Factors and outcomes associated with candidemia caused by non-albicans Candida spp. versus Candida albicans in children","volume":"46","author":"Lee","year":"2018","journal-title":"Am J. Infect. Control."},{"key":"B33","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1093\/infdis\/jir455","article-title":"Candida albicans Hgt1p, a multifunctional evasion molecule: complement inhibitor, CR3 analogue, and human immunodeficiency virus-binding molecule","volume":"204","author":"Lesiak-Markowicz","year":"2011","journal-title":"J. Infect. Dis."},{"key":"B34","doi-asserted-by":"publisher","first-page":"5035","DOI":"10.1172\/JCI71307","article-title":"CX3CR1-dependent renal macrophage survival promotes Candida control and host survival","volume":"123","author":"Lionakis","year":"2013","journal-title":"J. Clin. Invest."},{"key":"B35","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/S0167-4889(99)00112-3","article-title":"CR3, Fc\u03b3RIIA and Fc\u03b3RIIIB induce activation of the respiratory burst in human neutrophils: the role of intracellular Ca2+, phospholipase D and tyrosine phosphorylation","volume":"1452","author":"L\u00f6fgren","year":"1999","journal-title":"Biochim. Biophys. Acta."},{"key":"B36","volume-title":"The roles of Candida albicans Gpm1p and Tef1p in immune evasion and tissue invasion of the human host","author":"Lopez","year":"2013"},{"key":"B37","doi-asserted-by":"publisher","first-page":"e90796","DOI":"10.1371\/journal.pone.0090796","article-title":"Candida albicans uses the surface protein Gpm1 to attach to human endothelial cells and to keratinocytes via the adhesive protein vitronectin","volume":"9","author":"Lopez","year":"2014","journal-title":"PLoS ONE"},{"key":"B38","doi-asserted-by":"publisher","first-page":"912","DOI":"10.4049\/jimmunol.0901702","article-title":"Factor H and Factor H-related protein 1 bind to human neutrophils via complement receptor 3, mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity","volume":"184","author":"Losse","year":"2010","journal-title":"J. Immunol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.imlet.2017.05.014","article-title":"The role of CR3 (CD11b\/CD18) and CR4 (CD11c\/CD18) in complement-mediated phagocytosis and podosome formation by human phagocytes","volume":"189","author":"Luk\u00e1csi","year":"2017","journal-title":"Immunol. Lett."},{"key":"B40","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1574-695X.2000.tb01452.x","article-title":"Membrane attack complex formation on yeast as trigger of selective release of terminal complement proteins from human polymorphonuclear leukocytes","volume":"28","author":"Lukasser-Vogl","year":"2000","journal-title":"FEMS Immunol Med. Microbiol"},{"key":"B41","doi-asserted-by":"publisher","first-page":"8021","DOI":"10.1074\/jbc.M110.130138","article-title":"The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion","volume":"286","author":"Luo","year":"2011","journal-title":"J. Biol. Chem."},{"key":"B42","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.molimm.2017.07.010","article-title":"The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments","volume":"93","author":"Luo","year":"2018","journal-title":"Mol. Immunol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"2164","DOI":"10.4049\/jimmunol.1001011","article-title":"Secreted pH-regulated antigen 1 of Candida albicans blocks activation and conversion of complement C3","volume":"185","author":"Luo","year":"2010","journal-title":"J. Immunol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1093\/infdis\/jis718","article-title":"Glycerol-3-phosphate dehydrogenase 2 is a novel factor H-, factor H-like protein 1-, and plasminogen-binding surface protein of Candida albicans","volume":"207","author":"Luo","year":"","journal-title":"J. Infect. Dis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.molimm.2009.07.017","article-title":"Immune evasion of the human pathogenic yeast Candida albicans: Pra1 is a Factor H, FHL-1 and plasminogen binding surface protein","volume":"47","author":"Luo","year":"2009","journal-title":"Mol. Immunol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.molimm.2013.05.218","article-title":"Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans","volume":"56","author":"Luo","year":"","journal-title":"Mol. Immunol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"3264","DOI":"10.4049\/jimmunol.174.6.3264","article-title":"Coligation of the B cell receptor with complement receptor type 2 (CR2\/CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway","volume":"174","author":"Lyubchenko","year":"2005","journal-title":"J. Immunol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1186\/1471-2334-13-337","article-title":"Surveillance study of species distribution, antifungal susceptibility and mortality of nosocomial candidemia in a tertiary care hospital in China","volume":"13","author":"Ma","year":"2013","journal-title":"BMC Infect. Dis."},{"key":"B49","doi-asserted-by":"publisher","first-page":"4345","DOI":"10.1128\/IAI.00588-07","article-title":"Analysis of PRA1 and its relationship to Candida albicans-macrophage interactions","volume":"76","author":"Marcil","year":"2008","journal-title":"Infect. Immun."},{"key":"B50","doi-asserted-by":"publisher","first-page":"S142","DOI":"10.1093\/ofid\/ofy210.373","article-title":"Species distribution and trends of invasive candidiasis in the United States, 2009-2015, using a large electronic medical record database. S82","volume":"5","author":"Mehta","year":"2018","journal-title":"Open Forum Infect. Dis."},{"key":"B51","doi-asserted-by":"publisher","first-page":"6633","DOI":"10.1128\/IAI.72.11.6633-6641.2004","article-title":"The hyphal and yeast forms of Candida albicans bind the complement regulator C4b-binding protein","volume":"72","author":"Meri","year":"2004","journal-title":"Infect. Immun."},{"key":"B52","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.1128\/IAI.70.9.5185-5192.2002","article-title":"The yeast Candida albicans binds complement regulators Factor H and FHL-1","volume":"70","author":"Meri","year":"2002","journal-title":"Infect. Immun."},{"key":"B53","doi-asserted-by":"publisher","first-page":"262","DOI":"10.3389\/fimmu.2015.00262","article-title":"Complement system part I - molecular mechanisms of activation and regulation","volume":"6","author":"Merle","year":"2015","journal-title":"Front. Immunol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1643","DOI":"10.1084\/jem.175.6.1643","article-title":"A role for complement receptor-like molecules in iron acquisition by Candida albicans","volume":"175","author":"Moors","year":"1992","journal-title":"J. Exp. Med"},{"key":"B55","doi-asserted-by":"publisher","first-page":"5868","DOI":"10.1128\/IAI.72.10.5868-5876.2004","article-title":"Dysregulated inflammatory response to Candida albicans in a C5-deficient mouse strain","volume":"72","author":"Mullick","year":"2004","journal-title":"Infect. Immun."},{"key":"B56","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1128\/MMBR.67.3.400-428.2003","article-title":"Candida albicans secreted aspartyl proteinases in virulence and pathogenesis","volume":"67","author":"Naglik","year":"2003","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B57","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/nrmicro1815","article-title":"An integrated model of the recognition of Candida albicans by the innate immune system","volume":"6","author":"Netea","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"e206","DOI":"10.1097\/INF.0b013e3182863a1c","article-title":"Candida parapsilosis is a significant neonatal pathogen: a systematic review and meta-analysis","volume":"5","author":"Pammi","year":"2013","journal-title":"Pediatr. Infect. Dis. J."},{"key":"B59","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1097\/QAD.0b013e328322ffac","article-title":"Estimation of the current global burden of cryptococcal meningitis among persons living with HIV\/AIDS","volume":"23","author":"Park","year":"2009","journal-title":"AIDS"},{"key":"B60","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.jinf.2016.10.005","article-title":"Estimating the burden of invasive and serious fungal disease in the United Kingdom","volume":"74","author":"Pegorie","year":"2017","journal-title":"J. Infect."},{"key":"B61","doi-asserted-by":"publisher","first-page":"e101510","DOI":"10.1371\/journal.pone.0101510","article-title":"Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008","volume":"9","author":"Pfaller","year":"2014","journal-title":"PLoS ONE."},{"key":"B62","doi-asserted-by":"publisher","first-page":"2669","DOI":"10.1046\/j.1432-1327.2001.02152.x","article-title":"Secreted aspartic proteases of Candida albicans, Candida tropicalis, Candida parapsilosis and Candida lusitaniae: inhibition with peptidomimetic inhibitors","volume":"268","author":"Pichov\u00e1","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"B63","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1186\/s12879-016-1767-9","article-title":"Outbreak of candidemia caused by fluconazole resistant Candida parapsilosis strains in an intensive care unit","volume":"16","author":"Pinhati","year":"2016","journal-title":"BMC Infect. Dis."},{"key":"B64","doi-asserted-by":"publisher","first-page":"37537","DOI":"10.1074\/jbc.M707280200","article-title":"Gpm1p is a factor H-, FHL-1-, and plasminogen-binding surface protein of Candida albicans","volume":"282","author":"Poltermann","year":"2007","journal-title":"J. Biol. Chem."},{"key":"B65","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/ni.1923","article-title":"Complement: a key system for immune surveillance and homeostasis","volume":"11","author":"Ricklin","year":"2010","journal-title":"Nat. Immunol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.cmi.2014.07.013","article-title":"Burden of serious fungal infections in Spain","volume":"21","author":"Rodriguez-Tudela","year":"2015","journal-title":"Clin. Microbiol. Infect."},{"key":"B67","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3389\/fimmu.2015.00257","article-title":"Complement system part II : role in immunity","volume":"6","author":"Roumenina","year":"2015","journal-title":"Front. Immunol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bbagen.2016.11.023","article-title":"Three pentraxins C-reactive protein, serum amyloid p component and pentraxin 3 mediate complement activation using collectin CL-P1","volume":"1861","author":"Roy","year":"2017","journal-title":"Biochim. Biophys. Acta. Gen. Subj."},{"key":"B69","doi-asserted-by":"publisher","first-page":"e00162","DOI":"10.1128\/mBio.00162-13","article-title":"Complement component 3C3 and C3a receptor are required in chitin-dependent allergic sensitization to Aspergillus fumigatus but dispensable in chitin-induced innate allergic inflammation","volume":"4","author":"Roy","year":"2013","journal-title":"MBio"},{"key":"B70","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.chom.2007.06.002","article-title":"Phagocytosis by human neutrophils is stimulated by a unique fungal cell wall component","volume":"2","author":"Rubin-Bejerano","year":"2007","journal-title":"Cell Host Microbe."},{"key":"B71","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/S0174-3031(84)80081-5","article-title":"A variety of Candida proteinases and their possible targets of proteolytic attack in the host","volume":"257","author":"Ruchel","year":"1984","journal-title":"Zentralbl. Bakteriol. Mikrobiol. Hyg. A."},{"key":"B72","doi-asserted-by":"publisher","first-page":"e00484","DOI":"10.1128\/mSphere.00484-19","article-title":"Functional characterization of secreted aspartyl proteases in Candida parapsilosis","volume":"4","author":"Singh","year":"2019","journal-title":"mSphere"},{"key":"B73","doi-asserted-by":"publisher","first-page":"4745","DOI":"10.1002\/cncr.24507","article-title":"Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001-2007): stable incidence but changing epidemiology of a still frequently lethal infection","volume":"115","author":"Sipsas","year":"2009","journal-title":"Cancer"},{"key":"B74","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1128\/IAI.00650-10","article-title":"Regulation of innate immune response to Candida albicans infections by \u03b1M\u03b22-Pra1p interaction","volume":"79","author":"Soloviev","year":"2011","journal-title":"Infect Immun"},{"key":"B75","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1086\/314822","article-title":"Evidence for alphavbeta3 and alphavbeta5 integrin-like vitronectin (VN) receptors in Candida albicans and their involvement in yeast cell adhesion to VN","volume":"180","author":"Spreghini","year":"1999","journal-title":"J. Infect. Dis."},{"key":"B76","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3201\/eid2301.161198","article-title":"Epidemiology of hospitalizations associated with invasive candidiasis, United States, 2002\u20132012","volume":"23","author":"Strollo","year":"2016","journal-title":"Emerg. Infect. Dis."},{"key":"B77","doi-asserted-by":"publisher","first-page":"4566","DOI":"10.1038\/s41467-019-12381-5","article-title":"Fungal dissemination is limited by liver macrophage filtration of the blood","volume":"10","author":"Sun","year":"2019","journal-title":"Nat. Commun"},{"key":"B78","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1128\/IAI.01197-15","article-title":"Real-Time imaging of interactions of neutrophils with Cryptococcus neoformans demonstrates a crucial role of complement C5a-C5aR signaling","volume":"84","author":"Sun","year":"2015","journal-title":"Infect. Immun."},{"key":"B79","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.imlet.2015.08.009","article-title":"Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b\/CD18) and CR4 (CD11c\/CD18)","volume":"168","author":"Svoboda","year":"2015","journal-title":"Immunol. Lett."},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens8010040","article-title":"Candida albicans at host barrier sites: pattern recognition receptors and beyond","volume":"8","author":"Swidergall","year":"2019","journal-title":"Pathogens"},{"key":"B81","doi-asserted-by":"publisher","first-page":"S440","DOI":"10.1086\/431987","article-title":"The Role of the mannose-binding lectin in innate immunity","volume":"41","author":"Takahashi","year":"2005","journal-title":"Clin. Infect. Dis."},{"key":"B82","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1111\/j.1365-2710.2009.01107.x","article-title":"Toenail onychomycosis: an important global disease burden","volume":"35","author":"Thomas","year":"2010","journal-title":"J. Clin. Pharm. Ther."},{"key":"B83","doi-asserted-by":"publisher","first-page":"e00111","DOI":"10.1128\/CMR.00111-18","article-title":"Candida parapsilosis: from genes to the bedside","volume":"32","author":"T\u00f3th","year":"2019","journal-title":"Clin. Microbiol. Rev."},{"key":"B84","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1078\/1438-4221-00211","article-title":"Importance of the terminal complement components for immune defence against Candida","volume":"292","author":"Triebel","year":"2003","journal-title":"Int. J. Med. Microbiol"},{"key":"B85","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1128\/CMR.00013-08","article-title":"Candida parapsilosis, an emerging fungal pathogen","volume":"21","author":"Trofa","year":"2008","journal-title":"Clin. Microbiol. Rev."},{"key":"B86","doi-asserted-by":"publisher","first-page":"3679","DOI":"10.1128\/IAI.00233-09","article-title":"Complement C3 plays an essential role in the control of opportunistic fungal infections","volume":"77","author":"Tsoni","year":"2009","journal-title":"Infect. Immun."},{"key":"B87","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1111\/j.1462-5822.2005.00659.x","article-title":"Neutrophil extracellular traps capture and kill Candida albicans and hyphal forms","volume":"8","author":"Urban","year":"2006","journal-title":"Cell. Microbiol."},{"key":"B88","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.idc.2015.10.004","article-title":"The global burden of fungal diseases","volume":"30","author":"Vallabhaneni","year":"2016","journal-title":"Infect. Dis. Clin. North Am."},{"key":"B89","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1186\/1471-2180-8-229","article-title":"Mannose binding lectin plays a crucial role in innate immunity against yeast by enhanced complement activation and enhanced uptake of polymorphonuclear cells","volume":"8","author":"Van Asbeck","year":"2008","journal-title":"BMC Microbiol."},{"key":"B90","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1111\/j.1462-5822.2007.00981.x","article-title":"Macrophage complement receptors and pathogen clearance","volume":"9","author":"van Lookeren Campagne","year":"2007","journal-title":"Cellular Microbiol."},{"key":"B91","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1159\/000369493","article-title":"Effective neutrophil phagocytosis of Aspergillus fumigatus is mediated by classical pathway complement activation","volume":"7","author":"van Strijp","year":"2015","journal-title":"J. Innate Immun."},{"key":"B92","doi-asserted-by":"publisher","first-page":"e87","DOI":"10.1038\/emi.2017.74","article-title":"Epidemiology and antifungal susceptibility of candidemia isolates of non-albicans Candida species from cancer patients","volume":"6","author":"Wu","year":"2017","journal-title":"Emerg. Microbes Infect."},{"key":"B93","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/1-4020-8056-5_11","article-title":"Microbial evasion mechanisms against human complement","volume-title":"The Complement System","author":"W\u00fcrzner","year":"2004"},{"key":"B94","doi-asserted-by":"publisher","first-page":"368","DOI":"10.3389\/fimmu.2012.00368","article-title":"New insights for C5a and C5a receptors in sepsis","volume":"3","author":"Yan","year":"2012","journal-title":"Front. Immunol."},{"key":"B95","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1038\/nri2620","article-title":"Complement regulators and inhibitory proteins","volume":"9","author":"Zipfel","year":"2009","journal-title":"Nat. Rev. Immunol."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.00094\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T13:47:17Z","timestamp":1695908837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.00094\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,12]]},"references-count":95,"alternative-id":["10.3389\/fcimb.2020.00094"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2020.00094","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,12]]},"article-number":"94"}}