{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:13:37Z","timestamp":1766067217154,"version":"3.41.2"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2020.557027","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T14:52:28Z","timestamp":1600440748000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["In the Search of Potential Serodiagnostic Proteins to Discriminate Between Acute and Chronic Q Fever in Humans. Some Promising Outcomes"],"prefix":"10.3389","volume":"10","author":[{"given":"Anna","family":"Psaroulaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eirini","family":"Mathioudaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iosif","family":"Vranakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimosthenis","family":"Chochlakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouil","family":"Yachnakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Kokkini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Tsiotis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1099\/jmm.0.000704","article-title":"Detection of Coxiella burnetii in heart valve sections by fluorescence in situ hybridization","volume":"67","author":"Aistleitner","year":"2018","journal-title":"J. Med. Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.vetmic.2009.07.016","article-title":"Q fever","volume":"140","author":"Angelakis","year":"2010","journal-title":"Vet. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e1006922","DOI":"10.1371\/journal.ppat.1006922","article-title":"Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation","volume":"14","author":"Beare","year":"2018","journal-title":"PLoS Pathog."},{"key":"B4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1196\/annals.1355.010","article-title":"Identification, cloning, and expression of potential diagnostic markers for Q fever","volume":"1063","author":"Chao","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"B5","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1128\/IAI.00883-06","article-title":"Proteome and antigen profiling of Coxiella burnetii developmental forms","volume":"75","author":"Coleman","year":"2007","journal-title":"Infect. Immun."},{"key":"B6","doi-asserted-by":"crossref","DOI":"10.1385\/1-59259-049-7:301","volume-title":"Validation of Diagnostic Tests for Infectious Diseases","author":"Crowther","year":"2000"},{"key":"B7","doi-asserted-by":"publisher","first-page":"e0221247","DOI":"10.1371\/journal.pone.0221247","article-title":"Risk of chronic Q fever in patients with cardiac valvulopathy, seven years after a large epidemic in the Netherlands","volume":"14","author":"de Lange","year":"2019","journal-title":"PLoS ONE"},{"key":"B8","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1007\/s10096-006-0213-0","article-title":"Evaluation of rapid U Legionella Plus Test, a new immunochromatographic assay for detection of Legionella pneumophila serogroup 1 antigen in urine","volume":"25","author":"Diederen","year":"2006","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"4845","DOI":"10.1128\/AEM.00279-06","article-title":"A protective immune response is generated in rainbow trout by an OmpH-like surface antigen (P18) of Flavobacterium psychrophilum","volume":"72","author":"Dumetz","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1128\/CMR.00045-16","article-title":"From Q fever to Coxiella burnetii infection: a paradigm change","volume":"30","author":"Eldin","year":"2017","journal-title":"Clin. Microbiol. Rev."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/bcr-2013-202843","article-title":"Two rare manifestations of Q fever: splenic and hepatic abscesses and cerebral venous thrombosis, with literature review ma non troppo","author":"Gomes","year":"2014","journal-title":"BMJ Case Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.diagmicrobio.2013.11.009","article-title":"Evaluation of the rapid RIDAQUICK Campylobacter(R) test in a general hospital","volume":"78","author":"Gomez-Camarasa","year":"2014","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"B13","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0966-842X(96)81555-1","article-title":"Biosafety concerns and Coxiella burnetii","volume":"4","author":"Hackstadt","year":"1996","journal-title":"Trends Microbiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.diagmicrobio.2012.09.001","article-title":"Comparison of the performance of IFA, CFA, and ELISA assays for the serodiagnosis of acute Q fever by quality assessment","volume":"75","author":"Herremans","year":"2013","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"B15","doi-asserted-by":"publisher","first-page":"105","DOI":"10.2149\/tmh.2011-28","article-title":"Evaluation of the NOW malaria immunochromatographic test for quantitative diagnosis of falciparum and vivax malaria parasite density","volume":"39","author":"Katakai","year":"2011","journal-title":"Trop. Med. Health."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1586\/14787210.2013.840534","article-title":"Antimicrobial therapies for Q fever","volume":"11","author":"Kersh","year":"2013","journal-title":"Expert Rev. Anti Infect. Ther."},{"key":"B17","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/j.1574-695X.2011.00912.x","article-title":"Protein candidates for Q fever serodiagnosis","volume":"64","author":"Kowalczewska","year":"2012","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999","journal-title":"Clin. Microbiol. Rev."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1093\/cid\/ciy278","article-title":"Coxiella burnetii: a hidden pathogen in interstitial lung disease?","volume":"67","author":"Melenotte","year":"","journal-title":"Clin. Infect. Dis."},{"key":"B20","doi-asserted-by":"publisher","first-page":"e181580","DOI":"10.1001\/jamanetworkopen.2018.1580","article-title":"Clinical features and complications of Coxiella burnetii infections from the French National Reference Center for Q fever","volume":"1","author":"Melenotte","year":"","journal-title":"JAMA Netw. Open"},{"key":"B21","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.cimid.2011.12.008","article-title":"Q fever osteomyelitis: a case report and literature review","volume":"35","author":"Merhej","year":"2012","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"B22","doi-asserted-by":"publisher","first-page":"856","DOI":"10.3201\/eid2305.151159","article-title":"No such thing as chronic Q fever","volume":"23","author":"Million","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1128\/IAI.55.5.1144-1150.1987","article-title":"Comparative virulence of intra- and interstrain lipopolysaccharide variants of Coxiella burnetii in the guinea pig model","volume":"55","author":"Moos","year":"1987","journal-title":"Infect. Immun."},{"key":"B24","doi-asserted-by":"publisher","first-page":"4430","DOI":"10.1073\/pnas.0812074106","article-title":"Host cell-free growth of the Q fever bacterium Coxiella burnetii","volume":"106","author":"Omsland","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B25","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1099\/jmm.0.024778-0","article-title":"Q fever: the neglected biothreat agent","volume":"60","author":"Oyston","year":"2011","journal-title":"J. Med. Microbiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1016\/j.jprot.2011.04.016","article-title":"A proteomic approach to investigate the differential antigenic profile of two Coxiella burnetii strains","volume":"74","author":"Papadioti","year":"2011","journal-title":"J. Proteomics"},{"key":"B27","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1080\/01652176.2013.843809","article-title":"Clinical microbiology of Coxiella burnetii and relevant aspects for the diagnosis and control of the zoonotic disease Q fever","volume":"33","author":"Roest","year":"2013","journal-title":"Vet. Q."},{"key":"B28","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s10096-008-0621-4","article-title":"Identification of protein candidates for the serodiagnosis of Q fever endocarditis by an immunoproteomic approach","volume":"28","author":"Sekeyova","year":"2009","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B29","doi-asserted-by":"publisher","first-page":"173","DOI":"10.4149\/av_2010_03_173","article-title":"Characterization of antigens for Q fever serodiagnostics","volume":"54","author":"Sekeyova","year":"2010","journal-title":"Acta Virol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"347","DOI":"10.4149\/av_2017_314","article-title":"Workshop on Q fever","volume":"61","author":"Skultety","year":"2017","journal-title":"Acta Virol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.cimid.2011.11.006","article-title":"Serological survey of Q fever in Crete, southern Greece","volume":"35","author":"Vranakis","year":"2012","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"B32","doi-asserted-by":"publisher","first-page":"242","DOI":"10.3390\/pathogens8040242","article-title":"Com1 as a promising protein for the differential diagnosis of the two forms of Q fever","volume":"8","author":"Vranakis","year":"2019","journal-title":"Pathogens"},{"key":"B33","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s11427-013-4472-6","article-title":"Protein array of Coxiella burnetii probed with Q fever sera","volume":"56","author":"Wang","year":"2013","journal-title":"Sci. China Life Sci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.jinf.2011.12.014","article-title":"Chronic Q fever: review of the literature and a proposal of new diagnostic criteria","volume":"64","author":"Wegdam-Blans","year":"2012","journal-title":"J. Infect."},{"key":"B35","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1471-2180-12-35","article-title":"Potential serodiagnostic markers for Q fever identified in Coxiella burnetii by immunoproteomic and protein microarray approaches","volume":"12","author":"Xiong","year":"2012","journal-title":"BMC Microbiol."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.557027\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T14:52:32Z","timestamp":1600440752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.557027\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,18]]},"references-count":35,"alternative-id":["10.3389\/fcimb.2020.557027"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2020.557027","relation":{},"ISSN":["2235-2988"],"issn-type":[{"type":"electronic","value":"2235-2988"}],"subject":[],"published":{"date-parts":[[2020,9,18]]},"article-number":"557027"}}