{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:56:14Z","timestamp":1773388574076,"version":"3.50.1"},"reference-count":177,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2020.574405","type":"journal-article","created":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T12:12:13Z","timestamp":1599826333000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["Quantitative Visions of Reality at the Tick-Host Interface: Biochemistry, Genomics, Proteomics, and Transcriptomics as Measures of Complete Inventories of the Tick Sialoverse"],"prefix":"10.3389","volume":"10","author":[{"given":"Ben J.","family":"Mans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.ibmb.2006.10.002","article-title":"Transcriptome analysis of the salivary glands of Dermacentor andersoni Stiles (Acari: Ixodidae)","volume":"37","author":"Alarcon-Chaidez","year":"2007","journal-title":"Insect Biochem. Mol. Biol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1111\/j.1365-2583.2009.00863.x","article-title":"Transcriptome analysis of the salivary glands of the female tick Amblyomma americanum (Acari: Ixodidae)","volume":"18","author":"Aljamali","year":"2009","journal-title":"Insect Mol. Biol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1186\/1471-2164-11-450","article-title":"An insight into the sialotranscriptome of the brown dog tick, Rhipicephalus sanguineus","volume":"11","author":"Anatriello","year":"2010","journal-title":"BMC Genomics"},{"key":"B4","doi-asserted-by":"publisher","first-page":"127","DOI":"10.2741\/s504","article-title":"Advances in tick vaccinology in Brazil: from gene expression to immunoprotection","volume":"10","author":"Andreotti","year":"2018","journal-title":"Front. Biosci."},{"key":"B5","doi-asserted-by":"publisher","first-page":"318","DOI":"10.3389\/fphys.2019.00318","article-title":"Transcriptome and proteome response of Rhipicephalus annulatus tick vector to Babesia bigemina infection","volume":"10","author":"Antunes","year":"2019","journal-title":"Front. Physiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"6764","DOI":"10.1038\/s41598-019-42899-z","article-title":"RNA-seq analysis of the salivary glands and midgut of the argasid tick Ornithodoros rostratus","volume":"9","author":"Araujo","year":"2019","journal-title":"Sci. Rep"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.ttbdis.2018.03.024","article-title":"Integrative taxonomy of Afrotropical Ornithodoros (Ornithodoros) (Acari: Ixodida: Argasidae)","volume":"9","author":"Bakkes","year":"2018","journal-title":"Ticks Tick Borne Dis."},{"key":"B8","first-page":"161","article-title":"Bloodsucking ticks (Ixodideae)\u2014vectors of disease of man and animals","volume":"8","author":"Balashov","year":"1972","journal-title":"Misc. Pub. Entomol. Soc. Amer"},{"key":"B9","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.ijpara.2017.03.007","article-title":"Gene-enriched draft genome of the cattle tick Rhipicephalus microplus: assembly by the hybrid Pacific biosciences\/illumina approach enabled analysis of the highly repetitive genome","volume":"47","author":"Barrero","year":"2017","journal-title":"Int. J. Parasitol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1186\/1471-2164-12-328","article-title":"Evolutionary conserved microRNAs are ubiquitously expressed compared to tick-specific miRNAs in the cattle tick Rhipicephalus (Boophilus) microplus","volume":"12","author":"Barrero","year":"2011","journal-title":"BMC Genomics"},{"key":"B11","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/S0965-1748(98)00034-4","article-title":"Acetylcholinesterase cDNA of the cattle tick, Boophilus microplus: characterisation and role in organophosphate resistance","volume":"28","author":"Baxter","year":"1998","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1186\/s12864-019-6042-1","article-title":"Proteomic informed by transcriptomic for salivary glands components of the camel tick Hyalomma dromedarii","volume":"20","author":"Bensaoud","year":"","journal-title":"BMC Genomics"},{"key":"B13","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.pt.2019.06.012","article-title":"Noncoding RNAs in parasite-vector-host interactions","volume":"35","author":"Bensaoud","year":"","journal-title":"Trends Parasitol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1186\/s13071-018-2874-9","article-title":"De novo assembly and annotation of Hyalomma dromedarii tick (Acari: Ixodidae) sialotranscriptome with regard to gender differences in gene expression","volume":"11","author":"Bensaoud","year":"2018","journal-title":"Parasit. Vectors"},{"key":"B15","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1645\/0022-3395(2000)086[0516:IAMCOA]2.0.CO;2","article-title":"Isolation and molecular cloning of a secreted immunosuppresant protein from Dermacentor andersoni salivary gland","volume":"86","author":"Bergman","year":"2000","journal-title":"J. Parasitol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/S0020-7519(02)00027-9","article-title":"A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle","volume":"32","author":"Bishop","year":"2002","journal-title":"Int. J. Parasitol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"e12987","DOI":"10.1111\/cmi.12987","article-title":"The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector","volume":"21","author":"Bourret","year":"2019","journal-title":"Cell. Microbiol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1016\/j.ttbdis.2016.04.006","article-title":"Structural characterization of tick cement cones collected from in vivo and artificial membrane blood-fed lone star ticks (Amblyomma americanum)","volume":"7","author":"Bullard","year":"2016","journal-title":"Ticks Tick Borne Dis."},{"key":"B19","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.dci.2008.09.011","article-title":"IrAM-An alpha2-macroglobulin from the hard tick Ixodes ricinus: characterization and function in phagocytosis of a potential pathogen Chryseobacterium indologenes","volume":"33","author":"Buresova","year":"2009","journal-title":"Dev. Comp. Immunol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1186\/s13071-018-2932-3","article-title":"Whole body transcriptomes and new insights into the biology of the tick Ixodes ricinus","volume":"11","author":"Charrier","year":"2018","journal-title":"Parasit. Vectors"},{"key":"B21","doi-asserted-by":"publisher","first-page":"12923","DOI":"10.1038\/s41598-019-49641-9","article-title":"A transcriptome-based phylogenetic study of hard ticks (Ixodidae)","volume":"9","author":"Charrier","year":"2019","journal-title":"Sci. Rep."},{"key":"B22","doi-asserted-by":"publisher","first-page":"4638","DOI":"10.1038\/s41467-018-06214-0","article-title":"A deadly dance: the choreography of host-pathogen interactions, as revealed by single-cell technologies","volume":"9","author":"Chattopadhyay","year":"2018","journal-title":"Nat. Commun"},{"key":"B23","doi-asserted-by":"publisher","first-page":"jcs224212","DOI":"10.1242\/jcs.224212","article-title":"Message in a vesicle-trans-kingdom intercommunication at the vector-host interface","volume":"132","author":"Ch\u00e1vez","year":"2019","journal-title":"J. Cell Sci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"526","DOI":"10.2144\/96213pf02","article-title":"Full-length cDNA cloning and determination of mRNA 5' and 3' ends by amplification of adaptor-ligated cDNA","volume":"21","author":"Chenchik","year":"1996","journal-title":"Biotechniques"},{"key":"B25","first-page":"321","article-title":"Studies on the various glands of the tick Haemaphysalis spinigera Neumann 1897. 3. the salivary glands","volume":"22","author":"Chinery","year":"1965","journal-title":"Acta Trop"},{"key":"B26","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1093\/jmedent\/10.4.355","article-title":"The nature and origin of the \u201ccement\u201d substance at the site of attachment and feeding of adult Haemaphysalis spinigera (Ixodidae)","volume":"10","author":"Chinery","year":"1973","journal-title":"J. Med. Entomol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1186\/1471-2164-9-233","article-title":"Insight into the sialome of the castor bean tick, Ixodes ricinus","volume":"9","author":"Chmelar","year":"2008","journal-title":"BMC Genomics"},{"key":"B28","doi-asserted-by":"publisher","first-page":"900","DOI":"10.2307\/3278433","article-title":"Fine structure of the salivary glands of unfed male Dermacentor variabilis (say) (Ixodoidea: Ixodidae)","volume":"59","author":"Coons","year":"1973","journal-title":"J. Parasitol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3390\/vaccines8010091","article-title":"Quantitative proteomics identifies metabolic pathways affected by Babesia infection and blood feeding in the sialoproteome of the vector Rhipicephalus bursa","volume":"8","author":"Couto","year":"2020","journal-title":"Vaccines"},{"key":"B30","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s13071-017-2008-9","article-title":"Genome scaffolding and annotation for the pathogen vector Ixodes ricinus by ultra-long single molecule sequencing","volume":"10","author":"Cramaro","year":"2017","journal-title":"Parasit. Vectors"},{"key":"B31","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1186\/s12864-015-1981-7","article-title":"Integration of Ixodes ricinus genome sequencing with transcriptome and proteome annotation of the na\u00efve midgut","volume":"16","author":"Cramaro","year":"2015","journal-title":"BMC Genomics"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.3389\/fimmu.2019.01056","article-title":"Discovery of alpha-gal-containing antigens in North American tick species believed to induce red meat allergy","volume":"10","author":"Crispell","year":"2019","journal-title":"Front. Immunol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1086\/323351","article-title":"Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands","volume":"184","author":"Das","year":"2001","journal-title":"J. Infect. Dis"},{"key":"B34","doi-asserted-by":"publisher","first-page":"99","DOI":"10.4269\/ajtmh.2000.62.99","article-title":"Salp16, a gene induced in Ixodes scapularis salivary glands during tick feeding","volume":"62","author":"Das","year":"2000","journal-title":"Am. J. Trop. Med. Hyg"},{"key":"B35","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1016\/j.ttbdis.2016.01.014","article-title":"De novo assembly and annotation of the salivary gland transcriptome of Rhipicephalus appendiculatus male and female ticks during blood feeding","volume":"7","author":"de Castro","year":"2016","journal-title":"Ticks Tick Borne Dis"},{"key":"B36","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1186\/s13071-017-2312-4","article-title":"Sialotranscriptomics of Rhipicephalus zambeziensis reveals intricate expression profiles of secretory proteins and suggests tight temporal transcriptional regulation during blood-feeding","volume":"10","author":"de Castro","year":"2017","journal-title":"Parasit. Vectors"},{"key":"B37","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.mcp.2016.02.006","article-title":"Transcriptome of larvae representing the Rhipicephalus sanguineus complex","volume":"31","author":"De Marco","year":"2017","journal-title":"Mol. Cell. Probes"},{"key":"B38","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jprot.2013.01.015","article-title":"An insight into the proteome of the saliva of the argasid tick Ornithodoros moubata reveals important differences in saliva protein composition between the sexes","volume":"80","author":"D\u00edaz-Mart\u00edn","year":"2013","journal-title":"J. Proteomics"},{"key":"B39","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.pt.2019.06.014","article-title":"Evolutionary insights into the tick hologenome","volume":"35","author":"D\u00edaz-S\u00e1nchez","year":"2019","journal-title":"Trends Parasitol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"476","DOI":"10.3389\/fcimb.2017.00476","article-title":"Analysis of the salivary gland transcriptome of unfed and partially fed Amblyomma sculptum ticks and descriptive proteome of the saliva","volume":"7","author":"Esteves","year":"2017","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B41","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1645\/GE-1371.1","article-title":"Observations on Antricola ticks: small nymphs feed on mammalian hosts and have a salivary gland structure similar to ixodid ticks","volume":"94","author":"Estrada-Pe\u00f1a","year":"2008","journal-title":"J. Parasitol"},{"key":"B42","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/0040-8166(82)90035-0","article-title":"Salivary gland of the tick vector of East Coast fever","volume":"14","author":"Fawcett","year":"1982","journal-title":"IV. cell type selectivity and host cell responses to Theileria parva. Tissue Cell"},{"key":"B43","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/0040-8166(81)90003-3","article-title":"Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. II. cellular basis for fluid secretion in the type III acinus","volume":"13","author":"Fawcett","year":"1981","journal-title":"Tissue Cell"},{"key":"B44","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s10493-019-00390-4","article-title":"Proteomic analysis of saliva from partially and fully engorged adult female Rhipicephalus microplus (Acari: Ixodidae)","volume":"78","author":"Feng","year":"2019","journal-title":"Exp. Appl. Acarol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1016\/j.jprot.2011.07.015","article-title":"An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes","volume":"74","author":"Francischetti","year":"2011","journal-title":"J. Proteomics"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ibmb.2007.09.009","article-title":"An insight into the sialome of the soft tick, Ornithodorus parkeri","volume":"38","author":"Francischetti","year":"","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B47","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/S0006-291X(03)00857-X","article-title":"Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis","volume":"305","author":"Francischetti","year":"2003","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"B48","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.jprot.2008.07.006","article-title":"An insight into the salivary transcriptome and proteome of the soft tick and vector of epizootic bovine abortion, Ornithodoros coriaceus","volume":"71","author":"Francischetti","year":"","journal-title":"J. Proteomics"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/j.ibmb.2005.05.007","article-title":"The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae)","volume":"35","author":"Francischetti","year":"2005","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B50","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.2741\/3363","article-title":"The role of saliva in tick feeding","volume":"14","author":"Francischetti","year":"2009","journal-title":"Front. Biosci."},{"key":"B51","doi-asserted-by":"publisher","first-page":"3602","DOI":"10.1182\/blood-2001-12-0237","article-title":"Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa\/tissue factor complex","volume":"99","author":"Francischetti","year":"2002","journal-title":"Blood"},{"key":"B52","doi-asserted-by":"publisher","first-page":"12657","DOI":"10.1073\/pnas.2000605117","article-title":"Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition","volume":"117","author":"Franck","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B53","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1186\/1756-3305-7-430","article-title":"The sialotranscriptome of Amblyomma triste, Amblyomma parvum and Amblyomma cajennense ticks, uncovered by 454-based RNA-seq","volume":"7","author":"Garcia","year":"2014","journal-title":"Parasit. Vectors"},{"key":"B54","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/BF00052551","article-title":"Identification of anticoagulant activities in the salivary glands of the soft tick, Ornithodoros savignyi","volume":"19","author":"Gaspar","year":"1995","journal-title":"Exp. Appl. Acarol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/BF00052809","article-title":"Isolation and characterization of an anticoagulant from the salivary glands of the tick, Ornithodoros savignyi (Acari: Argasidae)","volume":"20","author":"Gaspar","year":"1996","journal-title":"Exp. Appl. Acarol"},{"key":"B56","doi-asserted-by":"publisher","first-page":"477","DOI":"10.3389\/fcimb.2019.00477","article-title":"Gene expression in the salivary gland of Rhipicephalus (Boophilus) microplus fed on tick-susceptible and tick-resistant hosts","volume":"9","author":"Giachetto","year":"2020","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B57","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1186\/1471-2164-14-135","article-title":"Why so many unknown genes?","volume":"14","author":"Gibson","year":"2013","journal-title":"partitioning orphans from a representative transcriptome of the lone star tick Amblyomma americanum. BMC Genomics"},{"key":"B58","doi-asserted-by":"publisher","first-page":"D707","DOI":"10.1093\/nar\/gku1117","article-title":"VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases","volume":"43","author":"Giraldo-Calder\u00f3n","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"B59","doi-asserted-by":"publisher","first-page":"104602","DOI":"10.1016\/j.dib.2019.104602","article-title":"The Pacific biosciences de novo assembled genome dataset from a parthenogenetic New Zealand wild population of the longhorned tick, Haemaphysalis longicornis Neumann, 1901","volume":"27","author":"Guerrero","year":"2019","journal-title":"Data Brief"},{"key":"B60","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.ibmb.2005.01.020","article-title":"BmiGI: a database of cDNAs expressed in Boophilus microplus, the tropical\/southern cattle tick","volume":"35","author":"Guerrero","year":"2005","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B61","doi-asserted-by":"publisher","first-page":"10507","DOI":"10.1038\/ncomms10507","article-title":"Genomic insights into the Ixodes scapularis tick vector of Lyme disease","volume":"7","author":"Gulia-Nuss","year":"2016","journal-title":"Nat. Commun"},{"key":"B62","doi-asserted-by":"publisher","first-page":"104008","DOI":"10.1016\/j.meegid.2019.104008","article-title":"De novo transcriptome sequencing and comparative analysis of Haemaphysalis flava Neumann, 1897 at larvae and nymph stages","volume":"75","author":"Guo","year":"2019","journal-title":"Infect. Genet. Evol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S0303-7207(98)00073-2","article-title":"Isolation of two functional retinoid X receptor subtypes from the ixodid tick, Amblyomma americanum (L.)","volume":"139","author":"Guo","year":"1998","journal-title":"Mol. Cell. Endocrinol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/j.pt.2018.04.001","article-title":"Exosome-mediated pathogen transmission by arthropod vectors","volume":"34","author":"Hackenberg","year":"2018","journal-title":"Trends Parasitol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1261\/rna.061168.117","article-title":"In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology","volume":"23","author":"Hackenberg","year":"2017","journal-title":"RNA"},{"key":"B66","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.ijpara.2017.08.018","article-title":"Identification and characterization of proteins in the Amblyomma americanum tick cement cone","volume":"48","author":"Hollmann","year":"2018","journal-title":"Int. J. Parasitol"},{"key":"B67","first-page":"99","article-title":"Some toxic and chemical properties of the oral secretion of the sand tampan, Ornithodoros savignyi (Audouin) (1827)","volume":"43","author":"Howell","year":"1975","journal-title":"Onderstepoort J. Vet. Res"},{"key":"B68","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1023\/A:1006198713791","article-title":"Cloning, nucleotide sequence and expression of the gene encoding factor Xa inhibitor from the salivary glands of the tick, Ornithodoros savignyi","volume":"22","author":"Joubert","year":"1998","journal-title":"Exp. Appl. Acarol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0041-0101(66)90003-1","article-title":"Isolation of tick paralysis toxin from Ixodes holocyclus","volume":"4","author":"Kaire","year":"1966","journal-title":"Toxicon"},{"key":"B70","doi-asserted-by":"crossref","first-page":"6702","DOI":"10.1016\/S0021-9258(17)37432-X","article-title":"Disagregin is a fibrinogen receptor antagonist lacking the Arg-Gly-Asp sequence from the tick, Ornithodoros moubata","volume":"269","author":"Karczewski","year":"1994","journal-title":"J. Biol. Chem"},{"key":"B71","doi-asserted-by":"publisher","first-page":"e0131292","DOI":"10.1371\/journal.pone.0131292","article-title":"An insight into the sialome of the Lone Star tick, Amblyomma americanum, with a glimpse on its time dependent gene expression","volume":"10","author":"Karim","year":"2015","journal-title":"PLoS ONE"},{"key":"B72","doi-asserted-by":"publisher","first-page":"e28525","DOI":"10.1371\/journal.pone.0028525","article-title":"A deep insight into the sialotranscriptome of the Gulf Coast tick, Amblyomma maculatum","volume":"6","author":"Karim","year":"2011","journal-title":"PLoS ONE"},{"key":"B73","doi-asserted-by":"crossref","first-page":"5450","DOI":"10.1016\/S0021-9258(18)53342-1","article-title":"Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation","volume":"268","author":"Keller","year":"1993","journal-title":"J. Biol. Chem"},{"key":"B74","doi-asserted-by":"publisher","first-page":"e0004323","DOI":"10.1371\/journal.pntd.0004323","article-title":"Ixodes scapularis tick saliva proteins sequentially secreted every 24 h during blood feeding","volume":"10","author":"Kim","year":"2016","journal-title":"PLoS Negl. Trop. Dis"},{"key":"B75","doi-asserted-by":"publisher","first-page":"e0007758","DOI":"10.1371\/journal.pntd.0007758","article-title":"Time-resolved proteomic profile of Amblyomma americanum tick saliva during feeding","volume":"14","author":"Kim","year":"2020","journal-title":"PLoS Negl. Trop. Dis"},{"key":"B76","doi-asserted-by":"publisher","first-page":"9103","DOI":"10.1038\/srep09103","article-title":"Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host","volume":"5","author":"Kotsyfakis","year":"2015","journal-title":"Sci. Rep"},{"key":"B77","doi-asserted-by":"publisher","first-page":"5409","DOI":"10.1093\/nar\/17.13.5409","article-title":"Effect of lambda packaging extract mcr restriction activity on DNA cloning","volume":"17","author":"Kretz","year":"1989","journal-title":"Nucleic Acids Res"},{"key":"B78","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"B79","doi-asserted-by":"publisher","first-page":"225","DOI":"10.4269\/ajtmh.2002.66.225","article-title":"Isolation of Ixodes ricinus salivary gland mRNA encoding factors induced during blood feeding","volume":"66","author":"Leboulle","year":"2002","journal-title":"Am. J. Trop. Med. Hyg"},{"key":"B80","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1146\/annurev-genom-083115-022413","article-title":"Advancements in next-generation sequencing","volume":"17","author":"Levy","year":"2016","journal-title":"Annu. Rev. Genomics Hum. Genet"},{"key":"B81","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.sbi.2013.02.013","article-title":"The impact of splicing on protein domain architecture","volume":"23","author":"Light","year":"2013","journal-title":"Curr. Opin. Struct. Biol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"101427","DOI":"10.1016\/j.ttbdis.2020.101427","article-title":"Analysis of microRNA expression profiles dynamic in different life stages of Haemaphysalis longicornis ticks by deep sequencing of small RNA libraries","volume":"11","author":"Liu","year":"2020","journal-title":"Ticks Tick Borne Dis"},{"key":"B83","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1006\/bbrc.1996.5948","article-title":"Construction of cDNA libraries from small amounts of total RNA using the suppression PCR effect","volume":"230","author":"Lukyanov","year":"1997","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"B84","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.gene.2015.01.019","article-title":"Identification and characterization of microRNAs by deep-sequencing in Hyalomma anatolicum anatolicum (Acari: Ixodidae) ticks","volume":"564","author":"Luo","year":"2015","journal-title":"Gene"},{"key":"B85","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1051\/parasite\/2019018","article-title":"Comparative analysis of microRNA profiles between wild and cultured Haemaphysalis longicornis (Acari, Ixodidae) ticks","volume":"26","author":"Luo","year":"2019","journal-title":"Parasite"},{"key":"B86","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1023\/A:1025342015065","article-title":"A proteomics approach to characterizing tick salivary secretions","volume":"28","author":"Madden","year":"2002","journal-title":"Exp. Appl. Acarol"},{"key":"B87","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s13071-019-3318-x","article-title":"A microRNA profile of saliva and role of miR-375 in Haemaphysalis longicornis (Ixodida: Ixodidae)","volume":"12","author":"Malik","year":"2019","journal-title":"Parasit. Vectors"},{"key":"B88","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/978-3-319-40740-1_17","article-title":"\u201cGlandular matrices and secretions: blood- feeding arthropods,\u201d","volume-title":"Extracellular Composite Matrices in Arthropods","author":"Mans","year":"2016"},{"key":"B89","doi-asserted-by":"publisher","first-page":"530","DOI":"10.3389\/fphys.2019.00530","article-title":"Chemical equilibrium at the tick-host feeding interface: a critical examination of biological relevance in hematophagous behavior","volume":"10","author":"Mans","year":"2019","journal-title":"Front. Physiol"},{"key":"B90","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.ibmb.2007.09.003","article-title":"Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior","volume":"38","author":"Mans","year":"2008","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B91","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.ttbdis.2016.02.002","article-title":"Ancestral reconstruction of tick lineages","volume":"7","author":"Mans","year":"2016","journal-title":"Ticks Tick Borne Dis"},{"key":"B92","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3389\/fcimb.2017.00413","article-title":"Gene duplication and protein evolution in tick-host interactions","volume":"7","author":"Mans","year":"2017","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B93","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/S0965-1748(01)00169-2","article-title":"Amino acid sequence and structure modeling of savignin, a thrombin inhibitor from the tick, Ornithodoros savignyi","volume":"32","author":"Mans","year":"","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B94","doi-asserted-by":"publisher","first-page":"21371","DOI":"10.1074\/jbc.M112060200","article-title":"Savignygrin, a platelet aggregation inhibitor from the soft tick, Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold","volume":"277","author":"Mans","year":"","journal-title":"J. Biol. Chem"},{"key":"B95","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1093\/molbev\/msg126","article-title":"The major tick salivary gland proteins and toxins from the soft tick, Ornithodoros savignyi, are part of the tick Lipocalin family: implications for the origins of tick toxicoses","volume":"20","author":"Mans","year":"2003","journal-title":"Mol. Biol. Evol"},{"key":"B96","first-page":"283","article-title":"The sand tampan, Ornithodoros savignyi, as a model for tick\u2013host interactions","volume":"100","author":"Mans","year":"","journal-title":"S. Afr. J. Sci."},{"key":"B97","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ibmb.2003.09.002","article-title":"Adaptation of ticks to a blood-feeding environment: evolution from a functional perspective","volume":"34","author":"Mans","year":"","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B98","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/S0041-0101(02)00098-3","article-title":"Pathogenic mechanisms of sand tampan toxicoses induced by the tick, Ornithodoros savignyi","volume":"40","author":"Mans","year":"","journal-title":"Toxicon"},{"key":"B99","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1023\/B:APPA.0000030012.47964.b3","article-title":"A reassessment of argasid tick salivary gland ultrastructure from an immuno-cytochemical perspective","volume":"33","author":"Mans","year":"2004","journal-title":"Exp. Appl. Acarol"},{"key":"B100","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1002\/1522-2683(200105)22:9<1739::AID-ELPS1739>3.0.CO;2-7","article-title":"Identification of putative proteins involved in granule biogenesis of tick salivary glands","volume":"22","author":"Mans","year":"2001","journal-title":"Electrophoresis"},{"key":"B101","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/nrg3068","article-title":"Next-generation transcriptome assembly","volume":"12","author":"Martin","year":"2011","journal-title":"Nat. Rev. Genet"},{"key":"B102","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3389\/fphys.2019.00529","article-title":"The transcriptome of the salivary glands of Amblyomma aureolatum reveals the antimicrobial peptide microplusin as an important factor for the tick protection against Rickettsia rickettsii infection","volume":"10","author":"Martins","year":"2019","journal-title":"Front. Physiol"},{"key":"B103","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.pt.2009.03.005","article-title":"Bovine immunity - a driver for diversity in Theileria parasites?","volume":"25","author":"McKeever","year":"2009","journal-title":"Trends Parasitol"},{"key":"B104","doi-asserted-by":"publisher","first-page":"100","DOI":"10.2307\/3281330","article-title":"Protein changes in the salivary glands of the female lone star tick, Amblyomma americanum, during feeding","volume":"68","author":"McSwain","year":"1982","journal-title":"J. Parasitol"},{"key":"B105","doi-asserted-by":"publisher","first-page":"297","DOI":"10.12688\/f1000research.13635.1","article-title":"A draft genome sequence for the Ixodes scapularis cell line, ISE6","volume":"7","author":"Miller","year":"2018","journal-title":"F1000Res"},{"key":"B106","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.parint.2016.10.011","article-title":"A deep insight into the whole transcriptome of midguts, ovaries and salivary glands of the Amblyomma sculptum tick","volume":"66","author":"Moreira","year":"2017","journal-title":"Parasitol. Int"},{"key":"B107","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1016\/j.ijpara.2014.07.003","article-title":"Proteomics informed by transcriptomics identifies novel secreted proteins in Dermacentor andersoni saliva","volume":"44","author":"Mudenda","year":"2014","journal-title":"Int. J. Parasitol"},{"key":"B108","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/S0965-1748(02)00240-0","article-title":"Four serine proteinase inhibitors (serpin) from the brown ear tick, Rhiphicephalus appendiculatus; cDNA cloning and preliminary characterization","volume":"33","author":"Mulenga","year":"2003","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B109","doi-asserted-by":"publisher","first-page":"e451","DOI":"10.1371\/journal.pone.0000451","article-title":"Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission","volume":"2","author":"Narasimhan","year":"2007","journal-title":"PLoS ONE"},{"key":"B110","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1046\/j.1365-2583.2002.00375.x","article-title":"A novel family of anticoagulants from the saliva of Ixodes scapularis","volume":"11","author":"Narasimhan","year":"2002","journal-title":"Insect Mol. Biol"},{"key":"B111","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/0041-0101(83)90219-2","article-title":"In search of the causal agents of tick toxicoses","volume":"3","author":"Neitz","year":"1983","journal-title":"Toxicon S"},{"key":"B112","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1439-0450.1986.tb00025.x","article-title":"Changes in the protein pattern in the salivary glands of paralysis inducing female Rhipicephalus evertsi evertsi during infestation","volume":"33","author":"Neitz","year":"1986","journal-title":"Zentralbl. Veterinarmed. B"},{"key":"B113","first-page":"142","article-title":"Purification of the toxic component in the oral secretion of the sand tampan Ornithodoros savignyi (Audouin) (1827)","volume":"22","author":"Neitz","year":"1969","journal-title":"J. S. Afr. Chem. Ind"},{"key":"B114","first-page":"443","article-title":"Biochemical studies on the salivary glands and haemolymph of Amblyomma hebraeum","volume":"54","author":"Neitz","year":"1987","journal-title":"Onderstepoort J. Vet. Res"},{"key":"B115","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1016\/j.ibmb.2004.07.002","article-title":"Genes transcribed in the salivary glands of female Rhipicephalus appendiculatus ticks infected with Theileria parva","volume":"34","author":"Nene","year":"2004","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B116","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1016\/S0020-7519(02)00159-5","article-title":"AvGI, an index of genes transcribed in the salivary glands of the ixodid tick Amblyomma variegatum","volume":"32","author":"Nene","year":"2002","journal-title":"Int. J. Parasitol"},{"key":"B117","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1006\/expr.1999.4448","article-title":"Savignin, a potent thrombin inhibitor isolated from the salivary glands of the tick, Ornithodoros savignyi (Acari: Argasidae)","volume":"93","author":"Nienaber","year":"1999","journal-title":"Exp. Parasitol"},{"key":"B118","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nature08909","article-title":"Expansion of the eukaryotic proteome by alternative splicing","volume":"463","author":"Nilsen","year":"2010","journal-title":"Nature"},{"key":"B119","doi-asserted-by":"publisher","first-page":"807","DOI":"10.2478\/s11686-019-00103-2","article-title":"De novo RNA-seq and functional annotation of Haemaphysalis longicornis","volume":"64","author":"Niu","year":"2019","journal-title":"Acta Parasitol"},{"key":"B120","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1016\/S0021-9258(19)41496-8","article-title":"High resolution two-dimensional electrophoresis of proteins","volume":"250","author":"O'Farrell","year":"1975","journal-title":"J. Biol. Chem"},{"key":"B121","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/s10493-010-9392-6","article-title":"Multiple transcripts encode glucose 6-phosphate dehydrogenase in the southern cattle tick, Rhipicephalus (Boophilus) microplus","volume":"53","author":"Olafson","year":"2011","journal-title":"Exp. Appl. Acarol"},{"key":"B122","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/j.ibmb.2007.07.003","article-title":"A proteomic approach to the identification of salivary proteins from the argasid ticks Ornithodoros moubata and Ornithodoros erraticus","volume":"37","author":"Oleaga","year":"2007","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B123","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.ttbdis.2013.05.001","article-title":"Proteome of Rhipicephalus sanguineus tick saliva induced by the secretagogues pilocarpine and dopamine","volume":"4","author":"Oliveira","year":"2013","journal-title":"Ticks Tick Borne Dis"},{"key":"B124","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/S1097-2765(00)80359-7","article-title":"Tick histamine-binding proteins: isolation, cloning, and three dimensional structure","volume":"3","author":"Paesen","year":"1999","journal-title":"Mol. Cell"},{"key":"B125","doi-asserted-by":"publisher","first-page":"D442","DOI":"10.1093\/nar\/gky1106","article-title":"The PRIDE database and related tools and resources in 2019: improving support for quantification data","volume":"47","author":"Perez-Riverol","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"B126","doi-asserted-by":"publisher","first-page":"e0006410","DOI":"10.1371\/journal.pntd.0006410","article-title":"Sialome diversity of ticks revealed by RNAseq of single tick salivary glands","volume":"12","author":"Perner","year":"2018","journal-title":"PLoS Negl. Trop. Dis"},{"key":"B127","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3390\/vetsci5020053","article-title":"Tick paralysis: solving an enigma","volume":"5","author":"Pienaar","year":"2018","journal-title":"Vet. Sci"},{"key":"B128","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.ttbdis.2014.08.002","article-title":"Bioinformatic analyses of male and female Amblyomma americanum tick expressed serine protease inhibitors (serpins)","volume":"6","author":"Porter","year":"2015","journal-title":"Ticks Tick Borne Dis"},{"key":"B129","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.jprot.2014.03.011","article-title":"Paleoproteomics explained to youngsters: how did the wedding of two-dimensional electrophoresis and protein sequencing spark proteomics on: let there be light","volume":"107","author":"Rabilloud","year":"2020","journal-title":"J. Proteomics"},{"key":"B130","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1186\/1471-2164-15-518","article-title":"A 24-48 h fed Amblyomma americanum tick saliva immuno-proteome","volume":"15","author":"Radulovi\u0107","year":"2014","journal-title":"BMC Genomics"},{"key":"B131","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1186\/s13071-019-3864-2","article-title":"Salivary gland proteome analysis of developing adult female Haemaphysalis longicornis ticks: molecular motor and TCA cycle-related proteins play an important role throughout development","volume":"12","author":"Ren","year":"2019","journal-title":"Parasit. Vectors"},{"key":"B132","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.ibmb.2005.11.005","article-title":"An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks","volume":"36","author":"Ribeiro","year":"2006","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B133","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/1471-2164-12-136","article-title":"A further insight into the sialome of the tropical bont tick, Amblyomma variegatum","volume":"12","author":"Ribeiro","year":"2011","journal-title":"BMC Genomics"},{"key":"B134","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.ibmb.2012.01.003","article-title":"The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food","volume":"42","author":"Ribeiro","year":"2012","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B135","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.ttbdis.2016.08.011","article-title":"An insight into the sialome of Hyalomma excavatum","volume":"8","author":"Ribeiro","year":"2017","journal-title":"Ticks Tick Borne Dis"},{"key":"B136","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/S0065-2806(09)37002-2","article-title":"From sialomes to the sialoverse: an insight into salivary potion of blood-feeding insects","volume":"37","author":"Ribeiro","year":"2009","journal-title":"Adv. Insect Physiol"},{"key":"B137","doi-asserted-by":"publisher","first-page":"374","DOI":"10.3389\/fcimb.2020.00374","article-title":"TickSialoFam (TSFam): a database that helps to classify tick salivary proteins, a review on tick salivary protein function and evolution, with considerations on the tick sialome switching phenomenon","volume":"10","author":"Ribeiro","year":"2020","journal-title":"Front. Cell. Infect. Microbiol"},{"key":"B138","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1017\/S0031182000003073","article-title":"The anatomy of Argas persicus (Oken 1818). part II","volume":"6","author":"Robinson","year":"1913","journal-title":"Parasitology"},{"key":"B139","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.ijpara.2017.07.007","article-title":"Transcriptome and toxin family analysis of the paralysis tick, Ixodes holocyclus","volume":"48","author":"Rodriguez-Valle","year":"2018","journal-title":"Int. J. Parasitol"},{"key":"B140","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1242\/jeb.137315","article-title":"Mechanistic underpinnings of dehydration stress in the American dog tick revealed through RNA-Seq and metabolomics","volume":"219","author":"Rosendale","year":"2016","journal-title":"J. Exp. Biol"},{"key":"B141","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1093\/jmedent\/9.2.143","article-title":"The subgenus Persicargas (Ixodoidea, Argasidae, Argas). 15. histology and histochemistry of the salivary glands of A. (P.) persicus (Oken)","volume":"9","author":"Roshdy","year":"1972","journal-title":"J. Med. Entomol."},{"key":"B142","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1046\/j.0962-1075.2001.00311.x","article-title":"A high affinity serotonin- and histamine-binding lipocalin from tick saliva","volume":"11","author":"Sangamnatdej","year":"2002","journal-title":"Insect Mol. Biol"},{"key":"B143","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/S0965-1748(03)00083-3","article-title":"Molecular cloning, structure and bait region splice variants of alpha2-macroglobulin from the soft tick Ornithodoros moubata","volume":"33","author":"Saravanan","year":"2003","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B144","doi-asserted-by":"publisher","first-page":"2725","DOI":"10.1074\/mcp.M114.039289","article-title":"A systems level analysis reveals transcriptomic and proteomic complexity in Ixodes ricinus midgut and salivary glands during early attachment and feeding","volume":"13","author":"Schwarz","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"B145","doi-asserted-by":"publisher","first-page":"4745","DOI":"10.1096\/fj.13-232140","article-title":"De novo Ixodes ricinus salivary gland transcriptome analysis using two next-generation sequencing methodologies","volume":"27","author":"Schwarz","year":"2013","journal-title":"FASEB J"},{"key":"B146","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1002\/psc.3052","article-title":"Structural and functional studies of differentially O-glycosylated analogs of a thrombin inhibitory peptide - variegin","volume":"23","author":"Shabareesh","year":"2017","journal-title":"J. Pept. Sci"},{"key":"B147","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1007\/s12010-015-1688-x","article-title":"Comparative profiling of microRNAs in male and female Rhipicephalus sanguineus","volume":"176","author":"Shao","year":"2015","journal-title":"Appl. Biochem. Biotechnol"},{"key":"B148","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1111\/brv.12384","article-title":"Tick attachment cement - reviewing the mysteries of a biological skin plug system","volume":"93","author":"Suppan","year":"2018","journal-title":"Biol. Rev. Camb. Philos. Soc"},{"key":"B149","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.molbiopara.2006.09.006","article-title":"Molecular characterisation of cAMP-dependent protein kinase (PK-A) catalytic subunit isoforms in the male tick, Amblyomma hebraeum","volume":"150","author":"Tabish","year":"2006","journal-title":"Mol. Biochem. Parasitol"},{"key":"B150","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.jprot.2014.12.014","article-title":"Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus","volume":"117","author":"Tan","year":"2015","journal-title":"J. Proteomics"},{"key":"B151","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1603\/ME11215","article-title":"Sequence polymorphism in acetylcholinesterase transcripts and genotyping survey of BmAchE1 in laboratory and Mexican strains of Rhipicephalus (Boophilus) microplus","volume":"49","author":"Temeyer","year":"2012","journal-title":"J. Med. Entomol"},{"key":"B152","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/nchem.2744","article-title":"Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors","volume":"9","author":"Thompson","year":"2017","journal-title":"Nat. Chem"},{"key":"B153","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1038\/1841078a0","article-title":"New cell types in the salivary glands of the brown ear tick, Rhipicephalus appendiculatus Neumann","volume":"184","author":"Till","year":"1959","journal-title":"Nature"},{"key":"B154","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1186\/s13071-015-0918-y","article-title":"Saliva from nymph and adult females of Haemaphysalis longicornis: a proteomic study","volume":"8","author":"Tirloni","year":"2015","journal-title":"Parasit. Vectors"},{"key":"B155","doi-asserted-by":"publisher","first-page":"103899","DOI":"10.1016\/j.jprot.2020.103899","article-title":"Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): insights into gene expression during blood feeding","author":"Tirloni","year":"2020","journal-title":"J. Proteomics"},{"key":"B156","doi-asserted-by":"publisher","first-page":"e94831","DOI":"10.1371\/journal.pone.0094831","article-title":"Proteomic analysis of cattle tick Rhipicephalus (Boophilus) microplus saliva: a comparison between partially and fully engorged females","volume":"9","author":"Tirloni","year":"2014","journal-title":"PLoS ONE"},{"key":"B157","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.tibs.2016.08.008","article-title":"Alternative splicing may not be the key to proteome complexity","volume":"42","author":"Tress","year":"2017","journal-title":"Trends Biochem. Sci"},{"key":"B158","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.ibmb.2004.10.009","article-title":"Proteome analysis of abundantly expressed proteins from unfed larvae of the cattle tick, Boophilus microplus","volume":"35","author":"Untalan","year":"2005","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B159","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.dci.2017.10.012","article-title":"IrC2\/Bf - A yeast and Borrelia responsive component of the complement system from the hard tick Ixodes ricinus","volume":"79","author":"Urbanov\u00e1","year":"2018","journal-title":"Dev. Comp. Immunol"},{"key":"B160","doi-asserted-by":"publisher","first-page":"18717","DOI":"10.1074\/jbc.M001486200","article-title":"Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis","volume":"275","author":"Valenzuela","year":"2000","journal-title":"J. Biol. Chem"},{"key":"B161","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1242\/jeb.205.18.2843","article-title":"Exploring the sialome of the tick Ixodes scapularis","volume":"205","author":"Valenzuela","year":"","journal-title":"J. Exp. Biol"},{"key":"B162","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/S0965-1748(02)00047-4","article-title":"Toward a description of the sialome of the adult female mosquito Aedes aegypti","volume":"32","author":"Valenzuela","year":"","journal-title":"Insect Biochem. Mol. Biol"},{"key":"B163","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1186\/s13071-018-3062-7","article-title":"A bite so sweet: the glycobiology interface of tick-host-pathogen interactions","volume":"11","author":"Vechtova","year":"2018","journal-title":"Parasit. Vectors"},{"key":"B164","doi-asserted-by":"publisher","first-page":"865","DOI":"10.2307\/3281836","article-title":"Isolation of a neurotoxin from the salivary glands of female Rhipicephalus evertsi evertsi","volume":"72","author":"Viljoen","year":"1986","journal-title":"J. Parasitol"},{"key":"B165","doi-asserted-by":"publisher","first-page":"3154","DOI":"10.1074\/mcp.M115.051938","article-title":"Integrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by Anaplasma phagocytophilum infection in tick cells","volume":"14","author":"Villar","year":"2015","journal-title":"Mol. Cell. Proteomics"},{"key":"B166","doi-asserted-by":"publisher","first-page":"555","DOI":"10.3390\/biom10040555","article-title":"Tick and host-derived compounds detected in the cement complex substance","volume":"10","author":"Villar","year":"2020","journal-title":"Biomolecules"},{"key":"B167","doi-asserted-by":"publisher","first-page":"e89564","DOI":"10.1371\/journal.pone.0089564","article-title":"A systems biology approach to the characterization of stress response in Dermacentor reticulatus tick unfed larvae","volume":"9","author":"Villar","year":"2014","journal-title":"PLoS ONE"},{"key":"B168","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1046\/j.0269-283x.2001.00328.x","article-title":"Molecular individuality and adaptation of the tick Rhipicephalus appendiculatus in changed feeding environments","volume":"15","author":"Wang","year":"2001","journal-title":"Med. Vet. Entomol"},{"key":"B169","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1023\/A:1006362929841","article-title":"Molecular individuality: polymorphism of salivary gland proteins in three species of ixodid tick","volume":"23","author":"Wang","year":"1999","journal-title":"Exp. Appl. Acarol"},{"key":"B170","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1017\/S003118200008077X","article-title":"Comparison of the proteins in salivary glands, saliva and haemolymph of Rhipicephalus appendiculatus female ticks during feeding","volume":"109","author":"Wang","year":"1994","journal-title":"Parasitology"},{"key":"B171","doi-asserted-by":"publisher","first-page":"17785","DOI":"10.1074\/jbc.271.30.17785","article-title":"Variabilin, a novel RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis","volume":"271","author":"Wang","year":"1996","journal-title":"J. Biol. Chem"},{"key":"B172","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1093\/molbev\/msx319","article-title":"BUSCO applications from quality assessments to gene prediction and phylogenomics","volume":"35","author":"Waterhouse","year":"2018","journal-title":"Mol. Biol. Evol"},{"key":"B173","doi-asserted-by":"crossref","first-page":"5445","DOI":"10.1016\/S0021-9258(18)53341-X","article-title":"Isolation of an inhibitor selective for collagen-stimulated platelet aggregation from the soft tick Ornithodoros moubata","volume":"268","author":"Waxman","year":"1993","journal-title":"J. Biol. Chem"},{"key":"B174","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1126\/science.2333510","article-title":"Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa","volume":"248","author":"Waxman","year":"1990","journal-title":"Science"},{"key":"B175","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1603\/0022-2585-40.6.890","article-title":"Cloning and sequencing of putative acetylcholinesterase cDNAs from the American dog tick, Dermacentor variabilis, and the brown dog tick, Rhipicephalus sanguineus (Acari: Ixodidae)","volume":"40","author":"Xu","year":"2003","journal-title":"J. Med. Entomol"},{"key":"B176","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.meegid.2015.03.010","article-title":"De novo sequencing, assembly and analysis of salivary gland transcriptome of Haemaphysalis flava and identification of sialoprotein genes","volume":"32","author":"Xu","year":"2015","journal-title":"Infect. Genet. Evol"},{"key":"B177","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s10493-012-9604-3","article-title":"Distinctive microRNA profiles in the salivary glands of Haemaphysalis longicornis related to tick blood-feeding","volume":"59","author":"Zhou","year":"2013","journal-title":"Exp. Appl. Acarol"}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.574405\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T23:06:45Z","timestamp":1668726405000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.574405\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,11]]},"references-count":177,"alternative-id":["10.3389\/fcimb.2020.574405"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2020.574405","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,11]]},"article-number":"574405"}}