{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T12:52:05Z","timestamp":1782910325552,"version":"3.54.5"},"reference-count":86,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2020.577428","type":"journal-article","created":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T11:45:46Z","timestamp":1601466346000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Evidence for Tethering of Human Cytomegalovirus Genomes to Host Chromosomes"],"prefix":"10.3389","volume":"10","author":[{"given":"Katrin","family":"Mauch-M\u00fccke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Sch\u00f6n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Paulus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Nevels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"104720","DOI":"10.1016\/j.antiviral.2020.104720","article-title":"Current understanding of human herpesvirus 6 (HHV-6) chromosomal integration","volume":"176","author":"Aimola","year":"2020","journal-title":"Antiviral Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"9802","DOI":"10.1128\/JVI.01436-13","article-title":"Myeloblastic cell lines mimic some but not all aspects of human cytomegalovirus experimental latency defined in primary CD34+ cell populations","volume":"87","author":"Albright","year":"2013","journal-title":"J. Virol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1111\/tra.12378","article-title":"Viral genome tethering to host cell chromatin: cause and consequences","volume":"17","author":"Aydin","year":"2016","journal-title":"Traffic"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e1004162","DOI":"10.1371\/journal.ppat.1004162","article-title":"Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses","volume":"10","author":"Aydin","year":"2014","journal-title":"PLoS Pathog."},{"key":"B5","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1126\/science.1120541","article-title":"The nucleosomal surface as a docking station for kaposi's sarcoma herpesvirus LANA","volume":"311","author":"Barbera","year":"","journal-title":"Science"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.4161\/cc.5.10.2768","article-title":"Kaposi's sarcoma-associated herpesvirus LANA hitches a ride on the chromosome","volume":"5","author":"Barbera","year":"","journal-title":"Cell Cycle"},{"key":"B7","doi-asserted-by":"publisher","first-page":"7295","DOI":"10.1128\/JVI.69.11.7295-7299.1995","article-title":"Cell cycle dependence of foamy retrovirus infection","volume":"69","author":"Bieniasz","year":"1995","journal-title":"J. Virol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1182\/blood.V93.1.394","article-title":"Peripheral blood CD14(+) cells from healthy subjects carry a circular conformation of latent cytomegalovirus genome","volume":"93","author":"Bolovan-Fritts","year":"1999","journal-title":"Blood"},{"key":"B9","doi-asserted-by":"publisher","first-page":"11208","DOI":"10.1128\/JVI.01178-16","article-title":"Phosphorylation requirement of murine leukemia virus p12","volume":"90","author":"Brzezinski","year":"","journal-title":"J. Virol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"11197","DOI":"10.1128\/JVI.01084-16","article-title":"Repression of the chromatin-tethering domain of murine leukemia virus p12","volume":"90","author":"Brzezinski","year":"","journal-title":"J. Virol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"e02170","DOI":"10.1128\/JVI.02170-17","article-title":"Plasmid partitioning by human tumor viruses","volume":"92","author":"Chiu","year":"2018","journal-title":"J. Virol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"444","DOI":"10.3390\/v10080444","article-title":"Molecular determinants and the regulation of human cytomegalovirus latency and reactivation","volume":"10","author":"Collins-McMillen","year":"2018","journal-title":"Viruses"},{"key":"B13","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/978-1-59745-406-3_15","article-title":"Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomes","volume":"463","author":"Cremer","year":"2008","journal-title":"Methods Mol. Biol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e1900132","DOI":"10.1002\/bies.201900132","article-title":"The interchromatin compartment participates in the structural and functional organization of the cell nucleus","volume":"42","author":"Cremer","year":"2020","journal-title":"Bioessays"},{"key":"B15","doi-asserted-by":"publisher","first-page":"2931","DOI":"10.1016\/j.febslet.2015.05.037","article-title":"The 4D nucleome: evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments","volume":"589","author":"Cremer","year":"2015","journal-title":"FEBS Lett."},{"key":"B16","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.biolcel.2004.07.002","article-title":"Higher order chromatin architecture in the cell nucleus: on the way from structure to function","volume":"96","author":"Cremer","year":"2004","journal-title":"Biol. Cell"},{"key":"B17","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1128\/JVI.72.1.142-150.1998","article-title":"The papillomavirus minor capsid protein, L2, induces localization of the major capsid protein, L1, and the viral transcription\/replication protein, E2, to PML oncogenic domains","volume":"72","author":"Day","year":"1998","journal-title":"J. Virol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.tim.2019.09.002","article-title":"Control of viral latency by episome maintenance proteins","volume":"28","author":"De Leo","year":"2020","journal-title":"Trends Microbiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.1128\/JVI.01909-09","article-title":"The latent origin of replication of Epstein-Barr virus directs viral genomes to active regions of the nucleus","volume":"84","author":"Deutsch","year":"2010","journal-title":"J. Virol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.ejcb.2010.05.006","article-title":"Differential relocation and stability of PML-body components during productive human cytomegalovirus infection: detailed characterization by live-cell imaging","volume":"89","author":"Dimitropoulou","year":"2010","journal-title":"Eur. J. Cell Biol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1002\/rmv.1862","article-title":"Cytomegalovirus latency and reactivation: recent insights into an age old problem","volume":"26","author":"Dupont","year":"2016","journal-title":"Rev. Med. Virol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"e1003103","DOI":"10.1371\/journal.ppat.1003103","article-title":"p12 tethers the murine leukemia virus pre-integration complex to mitotic chromosomes","volume":"8","author":"Elis","year":"2012","journal-title":"PLoS Pathog."},{"key":"B23","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.semcdb.2007.08.010","article-title":"The perichromatin region: a functional compartment in the nucleus that determines large-scale chromatin folding","volume":"18","author":"Fakan","year":"2007","journal-title":"Semin. Cell Dev. Biol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"e11911","DOI":"10.7554\/eLife.11911.012","article-title":"Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome","volume":"5","author":"Fang","year":"2016","journal-title":"Elife"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1098\/rspb.2008.1642","article-title":"Targeting mitotic chromosomes: a conserved mechanism to ensure viral genome persistence","volume":"276","author":"Feeney","year":"2009","journal-title":"Proc. Biol. Sci."},{"key":"B26","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/978-981-10-7230-7_10","article-title":"Chromosomal integration by human herpesviruses 6A and 6B","volume":"1045","author":"Flamand","year":"2018","journal-title":"Adv. Exp. Med. Biol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3389\/fcimb.2020.00130","article-title":"Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response","volume":"10","author":"Forte","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3390\/vaccines7030070","article-title":"Human cytomegalovirus cell tropism and host cell receptors","volume":"7","author":"Gerna","year":"2019","journal-title":"Vaccines"},{"key":"B29","doi-asserted-by":"publisher","first-page":"4992","DOI":"10.1073\/pnas.1721638115","article-title":"Superresolution microscopy reveals structural mechanisms driving the nanoarchitecture of a viral chromatin tether","volume":"115","author":"Grant","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B30","doi-asserted-by":"publisher","first-page":"e1005748","DOI":"10.1371\/journal.ppat.1005748","article-title":"Human cytomegalovirus immediate-early 1 protein rewires upstream STAT3 to downstream STAT1 signaling switching an IL6-type to an IFN\u03b3-like response","volume":"12","author":"Harwardt","year":"2016","journal-title":"PLoS Pathog."},{"key":"B31","doi-asserted-by":"publisher","first-page":"5515","DOI":"10.1073\/pnas.92.12.5515","article-title":"Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments","volume":"92","author":"Heller","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B32","doi-asserted-by":"publisher","first-page":"6694","DOI":"10.1073\/pnas.1421804112","article-title":"The 3D structure of kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA","volume":"112","author":"Hellert","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B33","doi-asserted-by":"publisher","first-page":"25789","DOI":"10.1074\/jbc.M116.746396","article-title":"Borna disease virus assembles porous cage-like viral factories in the nucleus","volume":"291","author":"Hirai","year":"2016","journal-title":"J. Biol. Chem."},{"key":"B34","doi-asserted-by":"publisher","first-page":"10444","DOI":"10.1128\/JVI.00833-08","article-title":"Binding STAT2 by the acidic domain of human cytomegalovirus IE1 promotes viral growth and is negatively regulated by SUMO","volume":"82","author":"Huh","year":"2008","journal-title":"J. Virol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/227168a0","article-title":"Characteristics of a human diploid cell designated MRC-5","volume":"227","author":"Jacobs","year":"1970","journal-title":"Nature"},{"key":"B36","doi-asserted-by":"publisher","first-page":"8819","DOI":"10.1073\/pnas.1604317113","article-title":"Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes","volume":"113","author":"Kim","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1107\/S1399004715008792","article-title":"Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein","volume":"71","author":"Klingl","year":"2015","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"B38","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.virol.2012.09.023","article-title":"Snapshots: chromatin control of viral infection","volume":"435","author":"Knipe","year":"2012","journal-title":"Virology"},{"key":"B39","doi-asserted-by":"publisher","first-page":"e1002016","DOI":"10.1371\/journal.ppat.1002016","article-title":"Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-\u03b3","volume":"7","author":"Knoblach","year":"2011","journal-title":"PLoS Pathog."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1126\/science.306682","article-title":"Acute myelogenous leukemia: a human cell line responsive to colony-stimulating activity","volume":"200","author":"Koeffler","year":"1978","journal-title":"Science"},{"key":"B41","doi-asserted-by":"publisher","first-page":"12854","DOI":"10.1128\/JVI.01164-09","article-title":"Physical requirements and functional consequences of complex formation between the cytomegalovirus IE1 protein and human STAT2","volume":"83","author":"Krauss","year":"2009","journal-title":"J. Virol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"11596","DOI":"10.1128\/JVI.76.22.11596-11604.2002","article-title":"Protein interactions targeting the latency-associated nuclear antigen of kaposi's sarcoma-associated herpesvirus to cell chromosomes","volume":"76","author":"Krithivas","year":"2002","journal-title":"J. Virol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1016\/0042-6822(89)90201-8","article-title":"Expression of the acidic nuclear immediate-early protein (IE1) of human cytomegalovirus in stable cell lines and its preferential association with metaphase chromosomes","volume":"172","author":"Lafemina","year":"1989","journal-title":"Virology"},{"key":"B44","doi-asserted-by":"publisher","first-page":"569","DOI":"10.15698\/mic2018.12.663","article-title":"Retroviral integration site selection: a running Gag?","volume":"5","author":"Lesbats","year":"2018","journal-title":"Microb. Cell"},{"key":"B45","doi-asserted-by":"publisher","first-page":"5509","DOI":"10.1073\/pnas.1621159114","article-title":"Structural basis for spumavirus GAG tethering to chromatin","volume":"114","author":"Lesbats","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B46","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1128\/JVI.68.1.510-516.1994","article-title":"Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus","volume":"68","author":"Lewis","year":"1994","journal-title":"J. Virol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1128\/JVI.01500-15","article-title":"Viral regulation of cell tropism in human cytomegalovirus","volume":"90","author":"Li","year":"2016","journal-title":"J. Virol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1126\/science.1132319","article-title":"An essential role for LEDGF\/p75 in HIV integration","volume":"314","author":"Llano","year":"2006","journal-title":"Science"},{"key":"B49","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1007\/s00418-018-1703-8","article-title":"Perichromatin region: a moveable feast","volume":"150","author":"Masiello","year":"2018","journal-title":"Histochem. Cell Biol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1016\/j.chom.2012.04.009","article-title":"Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection","volume":"11","author":"Matsumoto","year":"2012","journal-title":"Cell Host Microbe"},{"key":"B51","doi-asserted-by":"publisher","first-page":"2318","DOI":"10.1128\/JVI.01097-09","article-title":"The latency-associated nuclear antigen interacts with MeCP2 and nucleosomes through separate domains","volume":"84","author":"Matsumura","year":"2010","journal-title":"J. Virol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"e1000522","DOI":"10.1371\/journal.ppat.1000522","article-title":"LEDGF\/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors","volume":"5","author":"Meehan","year":"2009","journal-title":"PLoS Pathog."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1128\/JVI.02606-13","article-title":"Human cytomegalovirus major immediate-early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface","volume":"88","author":"M\u00fccke","year":"2013","journal-title":"J. Virol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"704","DOI":"10.3390\/v10120704","article-title":"Pathogen at the gates: human cytomegalovirus entry and cell tropism","volume":"10","author":"Nguyen","year":"2018","journal-title":"Viruses"},{"key":"B55","doi-asserted-by":"publisher","first-page":"2821","DOI":"10.3390\/ijms19092821","article-title":"Monocytes and macrophages as viral targets and reservoirs","volume":"19","author":"Nikitina","year":"2018","journal-title":"Int. J. Mol. Sci"},{"key":"B56","doi-asserted-by":"publisher","first-page":"11167","DOI":"10.1128\/JVI.01218-08","article-title":"Temporal dynamics of cytomegalovirus chromatin assembly in productively infected human cells","volume":"82","author":"Nitzsche","year":"2008","journal-title":"J. Virol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"e1008537","DOI":"10.1371\/journal.ppat.1008537","article-title":"Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1","volume":"16","author":"Paulus","year":"2020","journal-title":"PLoS Pathog."},{"key":"B58","doi-asserted-by":"publisher","first-page":"3840","DOI":"10.1073\/pnas.0600007103","article-title":"A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling","volume":"103","author":"Paulus","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B59","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.omtm.2017.10.001","article-title":"Interactions between retroviruses and the host cell genome","volume":"8","author":"Poletti","year":"2018","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1099\/vir.0.031377-0","article-title":"Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34(+) progenitors","volume":"92","author":"Poole","year":"2011","journal-title":"J. Gen. Virol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s00430-015-0401-6","article-title":"Sleepless latency of human cytomegalovirus","volume":"204","author":"Poole","year":"2015","journal-title":"Med. Microbiol. Immunol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0248-4900(92)90206-G","article-title":"Segregation of viral double-stranded and single-stranded DNA molecules in nuclei of adenovirus infected cells as revealed by electron microscope in situ hybridization","volume":"76","author":"Puvion-Dutilleul","year":"1992","journal-title":"Biol. Cell"},{"key":"B63","doi-asserted-by":"publisher","first-page":"e1000318","DOI":"10.1371\/journal.ppat.1000318","article-title":"Establishment of human papillomavirus infection requires cell cycle progression","volume":"5","author":"Pyeon","year":"2009","journal-title":"PLoS Pathog."},{"key":"B64","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.virol.2016.05.020","article-title":"Localization of latency-associated nuclear antigen (LANA) on mitotic chromosomes","volume":"496","author":"Rahayu","year":"2016","journal-title":"Virology"},{"key":"B65","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1128\/JVI.79.1.225-233.2005","article-title":"The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication","volume":"79","author":"Reinhardt","year":"2005","journal-title":"J. Virol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"10763","DOI":"10.1128\/JVI.01197-13","article-title":"Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus","volume":"87","author":"Reitsma","year":"2013","journal-title":"J. Virol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1002\/rmv.645","article-title":"Human cytomegalovirus tropism for endothelial\/epithelial cells: scientific background and clinical implications","volume":"20","author":"Revello","year":"2010","journal-title":"Rev. Med. Virol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1002\/j.1460-2075.1993.tb05858.x","article-title":"Integration of murine leukemia virus DNA depends on mitosis","volume":"12","author":"Roe","year":"1993","journal-title":"EMBO J."},{"key":"B69","doi-asserted-by":"publisher","first-page":"e1004512","DOI":"10.1371\/journal.ppat.1004512","article-title":"Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions","volume":"10","author":"Scherer","year":"2014","journal-title":"PLoS Pathog."},{"key":"B70","doi-asserted-by":"publisher","first-page":"9487","DOI":"10.1073\/pnas.1221736110","article-title":"Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag","volume":"110","author":"Schneider","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B71","doi-asserted-by":"publisher","first-page":"7923","DOI":"10.1128\/JVI.71.10.7923-7932.1997","article-title":"Adenovirus type 12 DNA firmly associates with mammalian chromosomes early after virus infection or after DNA transfer by the addition of DNA to the cell culture medium","volume":"71","author":"Schr\u00f6er","year":"1997","journal-title":"J. Virol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1099\/vir.0.037986-0","article-title":"The chromatin-tethering domain of human cytomegalovirus immediate-early (IE) 1 mediates associations of IE1, PML and STAT2 with mitotic chromosomes, but is not essential for viral replication","volume":"93","author":"Shin","year":"2012","journal-title":"J. Gen. Virol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s007050050008","article-title":"Human cytomegalovirus induced inhibition of hematopoietic cell line growth is initiated by events taking place before translation of viral gene products","volume":"145","author":"Sindre","year":"2000","journal-title":"Arch. Virol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/978-3-540-77349-8_4","article-title":"Cytomegalovirus cell tropism","volume":"325","author":"Sinzger","year":"","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1099\/vir.0.83286-0","article-title":"Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40\/E","volume":"89","author":"Sinzger","year":"","journal-title":"J. Gen. Virol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/978-1-60761-789-1_8","article-title":"3D-FISH on cultured cells combined with immunostaining","volume":"659","author":"Solovei","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.chom.2014.06.006","article-title":"Maintenance and replication of the human cytomegalovirus genome during latency","volume":"16","author":"Tarrant-Elorza","year":"2014","journal-title":"Cell Host Microbe"},{"key":"B78","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1111\/j.1600-0854.2008.00792.x","article-title":"Chromatin tethering of incoming foamy virus by the structural Gag protein","volume":"9","year":"2008","journal-title":"Traffic"},{"key":"B79","first-page":"1168","article-title":"Mechanism of nuclear transport and persistent infection of Borna disease virus","volume":"52","author":"Tomonaga","year":"2007","journal-title":"Tanpakushitsu Kakusan Koso"},{"key":"B80","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1002\/0471142727.mb2804s106","article-title":"Detection of mycoplasma contamination in cell cultures","author":"Uphoff","year":"2014","journal-title":"Curr. Protoc. Mol. Biol. 106"},{"key":"B81","doi-asserted-by":"publisher","first-page":"e1007117","DOI":"10.1371\/journal.ppat.1007117","article-title":"Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis","volume":"14","author":"Wanaguru","year":"2018","journal-title":"PLoS Pathog."},{"key":"B82","doi-asserted-by":"publisher","first-page":"385","DOI":"10.15698\/mic2018.08.643","article-title":"Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins","volume":"5","author":"Wanaguru","year":"2018","journal-title":"Microb. Cell"},{"key":"B83","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/1742-4690-9-83","article-title":"The gammaretroviral p12 protein has multiple domains that function during the early stages of replication","volume":"9","author":"Wight","year":"2012","journal-title":"Retrovirology"},{"key":"B84","doi-asserted-by":"publisher","first-page":"e1004474","DOI":"10.1371\/journal.ppat.1004474","article-title":"The N-terminus of murine leukaemia virus p12 protein is required for mature core stability","volume":"10","author":"Wight","year":"2014","journal-title":"PLoS Pathog."},{"key":"B85","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1099\/0022-1317-79-5-1233","article-title":"Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product","volume":"79","author":"Wilkinson","year":"1998","journal-title":"J. Gen. Virol."},{"key":"B86","doi-asserted-by":"publisher","first-page":"13126","DOI":"10.1073\/pnas.1305548110","article-title":"Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein","volume":"110","author":"Zalckvar","year":"2013","journal-title":"Proc. Natl. Acad. Sci U.S.A."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.577428\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T11:45:49Z","timestamp":1601466349000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcimb.2020.577428\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,30]]},"references-count":86,"alternative-id":["10.3389\/fcimb.2020.577428"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2020.577428","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,30]]},"article-number":"577428"}}