{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:02:15Z","timestamp":1790787735749,"version":"4.1.0"},"reference-count":221,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T00:00:00Z","timestamp":1603756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006492","name":"Division of Intramural Research, National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"DOI":"10.3389\/fcimb.2020.587933","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T04:11:56Z","timestamp":1603771916000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":76,"title":["Host-Malaria Parasite Interactions and Impacts on Mutual Evolution"],"prefix":"10.3389","volume":"10","author":[{"given":"Xin-zhuan","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deirdre A.","family":"Joy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,10,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/01.inf.0000256735.05098.01","article-title":"Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: observations from vaccination trials in Guinea-Bissau","volume":"26","author":"Aaby","year":"2007","journal-title":"Pediatr. Infect. Dis. J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1016\/S0140-6736(03)13771-3","article-title":"Differences in female-male mortality after high-titre measles vaccine and association with subsequent vaccination with diphtheria-tetanus-pertussis and inactivated poliovirus: reanalysis of West African studies","volume":"361","author":"Aaby","year":"2003","journal-title":"Lancet"},{"key":"B3","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/S0022-3476(09)90015-4","article-title":"Long-term survival after Edmonston-Zagreb measles vaccination in Guinea-Bissau: increased female mortality rate","volume":"122","author":"Aaby","year":"1993","journal-title":"J. Pediatr."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1016\/S0140-6736(15)00693-5","article-title":"RTS,S\/AS01 malaria vaccine and child mortality","volume":"386","author":"Aaby","year":"2015","journal-title":"Lancet"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e1006447","DOI":"10.1371\/journal.ppat.1006447","article-title":"Rapid identification of genes controlling virulence and immunity in malaria parasites","volume":"13","author":"Abkallo","year":"2017","journal-title":"PLoS Pathog."},{"key":"B6","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1080\/00034983.1923.11684345","article-title":"Malaria in chinpanzees in Sierra Leone","volume":"17","author":"Adler","year":"1923","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1179\/135100003225002952","article-title":"The Haldane malaria hypothesis: facts, artifacts, and a prophecy","volume":"8","author":"Akide-Ndunge","year":"2003","journal-title":"Redox Rep."},{"key":"B8","doi-asserted-by":"publisher","first-page":"e1002992","DOI":"10.1371\/journal.pgen.1002992","article-title":"Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites","volume":"8","author":"Amambua-Ngwa","year":"2012","journal-title":"PLoS Genet"},{"key":"B9","doi-asserted-by":"publisher","first-page":"4093","DOI":"10.1128\/IAI.66.9.4093-4099.1998","article-title":"Cloned lines of Plasmodium berghei ANKA differ in their abilities to induce experimental cerebral malaria","volume":"66","author":"Amani","year":"1998","journal-title":"Infect. Immun."},{"key":"B10","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/j.ijpara.2016.05.009","article-title":"Genome-scale comparison of expanded gene families in Plasmodium ovale wallikeri and Plasmodium ovale curtisi with Plasmodium malariae and with other Plasmodium species","volume":"46","author":"Ansari","year":"2016","journal-title":"Int. J. Parasitol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3791\/58691","article-title":"Quantification of antibody-dependent enhancement of the Zika virus in primary human cells","volume":"143","author":"Asad","year":"2019","journal-title":"J. Vis. Exp"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1016\/S0140-6736(18)30324-6","article-title":"Malaria","volume":"391","author":"Ashley","year":"2018","journal-title":"Lancet"},{"key":"B13","doi-asserted-by":"publisher","first-page":"4","DOI":"10.12688\/wellcomeopenres.9876.1","article-title":"A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes","volume":"1","author":"Auburn","year":"2016","journal-title":"Wellcome Open Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e1003430","DOI":"10.1371\/journal.ppat.1003430","article-title":"DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells","volume":"9","author":"Avril","year":"2013","journal-title":"PLoS Pathog"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e1007906","DOI":"10.1371\/journal.ppat.1007906","article-title":"Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression","volume":"15","author":"Bachmann","year":"2019","journal-title":"PLoS Pathog."},{"key":"B16","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/j.1462-5822.2006.00798.x","article-title":"Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liver","volume":"9","author":"Baer","year":"2007","journal-title":"Cell. Microbiol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1641","DOI":"10.1038\/srep01641","article-title":"Intra-specific diversity of Serratia marcescens in Anopheles mosquito midgut defines Plasmodium transmission capacity","volume":"3","author":"Bando","year":"2013","journal-title":"Sci. Rep."},{"key":"B18","doi-asserted-by":"publisher","first-page":"6099","DOI":"10.1016\/j.vaccine.2008.09.004","article-title":"Mixed allele malaria vaccines: host protection and within-host selection","volume":"26","author":"Barclay","year":"2008","journal-title":"Vaccine"},{"key":"B19","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/0092-8674(95)90054-3","article-title":"Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes","volume":"82","author":"Baruch","year":"1995","journal-title":"Cell"},{"key":"B20","doi-asserted-by":"publisher","first-page":"eaau1458","DOI":"10.1126\/scitranslmed.aau1458","article-title":"Challenges and strategies for developing efficacious and long-lasting malaria vaccines","volume":"11","author":"Beeson","year":"2019","journal-title":"Sci. Transl. Med."},{"key":"B21","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1097\/BOR.0000000000000564","article-title":"Sex bias in autoimmunity","volume":"31","author":"Billi","year":"2019","journal-title":"Curr. Opin. Rheumatol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.ebiom.2016.05.015","article-title":"Complement and antibody-mediated enhancement of red blood cell invasion and growth of Malaria parasites","volume":"9","author":"Biryukov","year":"2016","journal-title":"EBioMedicine"},{"key":"B23","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1080\/00034983.1922.11684303","article-title":"A parasite resembling Plasmodium falciparum in chimpanzee","volume":"16","author":"Blacklock","year":"1922","journal-title":"Ann. Trop. Med. Prasitol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1101\/gr.218123.116","article-title":"Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals","volume":"28","author":"Bohme","year":"2018","journal-title":"Genome Res."},{"key":"B25","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12936-015-0622-6","article-title":"Diversity of malaria parasites in great apes in Gabon","volume":"14","author":"Boundenga","year":"2015","journal-title":"Malar. J."},{"key":"B26","doi-asserted-by":"publisher","first-page":"34","DOI":"10.3389\/fcimb.2018.00034","article-title":"Plasmodium vivax biology: insights provided by genomics, transcriptomics and proteomics","volume":"8","author":"Bourgard","year":"2018","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.cell.2017.10.020","article-title":"Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum","volume":"171","author":"Brancucci","year":"2017","journal-title":"Cell"},{"key":"B28","first-page":"827","article-title":"Researches on thalassemia and malaria in Italy and the origins of the \u201cHaldane hypothesis\u201d","volume":"20","author":"Canali","year":"2008","journal-title":"Med. Secoli."},{"key":"B29","first-page":"23","article-title":"The genome of model malaria parasites, and comparative genomics","volume":"7","author":"Carlton","year":"2005","journal-title":"Curr. Issues Mol. Biol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1038\/nature07327","article-title":"Comparative genomics of the neglected human malaria parasite Plasmodium vivax","volume":"455","author":"Carlton","year":"2008","journal-title":"Nature"},{"key":"B31","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1128\/CMR.15.4.564-594.2002","article-title":"Evolutionary and historical aspects of the burden of malaria","volume":"15","author":"Carter","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"B32","doi-asserted-by":"publisher","first-page":"e0003566","DOI":"10.1371\/journal.pntd.0003566","article-title":"Comparative analysis of field-isolate and monkey-adapted Plasmodium vivax genomes","volume":"9","author":"Chan","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"B33","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1016\/j.ijpara.2010.02.003","article-title":"A single parasite gene determines strain-specific protective immunity against malaria: the role of the merozoite surface protein I","volume":"40","author":"Cheesman","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2996","DOI":"10.1128\/IAI.74.5.2996-3001.2006","article-title":"Mixed strain infections and strain-specific protective immunity in the rodent malaria parasite Plasmodium chabaudi chabaudi in mice","volume":"74","author":"Cheesman","year":"2006","journal-title":"Infect. Immun."},{"key":"B35","doi-asserted-by":"publisher","first-page":"e16629","DOI":"10.1371\/journal.pone.0016629","article-title":"A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa","volume":"6","author":"Chen","year":"2011","journal-title":"PLoS ONE"},{"key":"B36","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1038\/28660","article-title":"Developmental selection of var gene expression in Plasmodium falciparum","volume":"394","author":"Chen","year":"1998","journal-title":"Nature"},{"key":"B37","doi-asserted-by":"publisher","first-page":"e1004812","DOI":"10.1371\/journal.pgen.1004812","article-title":"Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis","volume":"10","author":"Claessens","year":"2014","journal-title":"PLoS Genet."},{"key":"B38","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.tig.2014.12.005","article-title":"Paths to a malaria vaccine illuminated by parasite genomics","volume":"31","author":"Conway","year":"2015","journal-title":"Trends Genet."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S0031182000059217","article-title":"The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients","volume":"103","author":"Conway","year":"1991","journal-title":"Parasitology"},{"key":"B40","doi-asserted-by":"publisher","first-page":"212","DOI":"10.3389\/fimmu.2019.00212","article-title":"Analysis of predicted host-parasite interactomes reveals commonalities and specificities related to parasitic lifestyle and tissues tropism","volume":"10","author":"Cuesta-Astroz","year":"2019","journal-title":"Front. Immunol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.actatropica.2009.10.025","article-title":"Erythrocyte binding ligands in malaria parasites: intracellular trafficking and parasite virulence","volume":"114","author":"Culleton","year":"2010","journal-title":"Acta Trop."},{"key":"B42","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1101\/gr.2866205","article-title":"Linkage group selection: rapid gene discovery in malaria parasites","volume":"15","author":"Culleton","year":"2005","journal-title":"Genome Res."},{"key":"B43","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/j.1365-3024.2010.01251.x","article-title":"Strain-specific immunity induced by immunization with pre-erythrocytic stages of Plasmodium chabaudi","volume":"33","author":"Culleton","year":"2011","journal-title":"Parasite Immunol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"e4285","DOI":"10.1371\/journal.pone.0004285","article-title":"Rapid changes in transcription profiles of the Plasmodium yoelii yir multigene family in clonal populations: lack of epigenetic memory?","volume":"4","author":"Cunningham","year":"2009","journal-title":"PLoS ONE"},{"key":"B45","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.molbiopara.2009.12.010","article-title":"The pir multigene family of Plasmodium: antigenic variation and beyond","volume":"170","author":"Cunningham","year":"2010","journal-title":"Mol. Biochem. Parasitol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/s12920-019-0564-x","article-title":"Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects","volume":"12","author":"Damena","year":"2019","journal-title":"BMC Med Genomics"},{"key":"B47","doi-asserted-by":"publisher","first-page":"1544","DOI":"10.1093\/molbev\/mst080","article-title":"Evidence for polygenic adaptation to pathogens in the human genome","volume":"30","author":"Daub","year":"2013","journal-title":"Mol. Biol. Evol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"E4103","DOI":"10.1073\/pnas.1613018114","article-title":"Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West Africa","volume":"114","author":"Day","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B49","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1111\/imr.12828","article-title":"Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites","volume":"293","author":"de Jong","year":"2020","journal-title":"Immunol. Rev"},{"key":"B50","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1146\/annurev-micro-090816-093841","article-title":"Variant gene expression and antigenic variation by malaria parasites","volume":"71","author":"Deitsch","year":"2017","journal-title":"Annu. Rev. Microbiol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1186\/s12936-018-2622-9","article-title":"Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka","volume":"17","author":"Dewasurendra","year":"2018","journal-title":"Malar. J."},{"key":"B52","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.chom.2018.06.008","article-title":"Malaria vaccines: recent advances and new horizons","volume":"24","author":"Draper","year":"2018","journal-title":"Cell Host Microbe"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e51023","DOI":"10.1371\/journal.pone.0051023","article-title":"Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria","volume":"7","author":"Drew","year":"2012","journal-title":"PLoS ONE"},{"key":"B54","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1111\/j.1469-0691.2012.03825.x","article-title":"Ape Plasmodium parasites as a source of human outbreaks","volume":"18","author":"Duval","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"B55","doi-asserted-by":"publisher","first-page":"10561","DOI":"10.1073\/pnas.1005435107","article-title":"African apes as reservoirs of Plasmodium falciparum and the origin and diversification of the Laverania subgenus","volume":"107","author":"Duval","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B56","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1038\/s41467-018-03807-7","article-title":"Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections","volume":"9","author":"Early","year":"2018","journal-title":"Nat. Commun."},{"key":"B57","doi-asserted-by":"publisher","first-page":"e1007023","DOI":"10.1371\/journal.pgen.1007023","article-title":"High rate of adaptation of mammalian proteins that interact with Plasmodium and related parasites","volume":"13","author":"Ebel","year":"2017","journal-title":"PLoS Genet"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1073\/pnas.0409652102","article-title":"A monkey's tale: the origin of Plasmodium vivax as a human malaria parasite","volume":"102","author":"Escalante","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/microbiolspec.AME-0010-2019","article-title":"Malaria molecular epidemiology: an evolutionary genetics perspective","volume":"7","author":"Escalante","year":"2019","journal-title":"Microbiol. Spectr."},{"key":"B60","doi-asserted-by":"publisher","first-page":"105364","DOI":"10.1016\/j.actatropica.2020.105364","article-title":"Evolutionary ecology, taxonomy, and systematics of avian malaria and related parasites","volume":"204","author":"Fecchio","year":"2020","journal-title":"Acta Trop."},{"key":"B61","doi-asserted-by":"publisher","first-page":"e45542","DOI":"10.1371\/journal.pone.0045542","article-title":"The dynamics of natural Plasmodium falciparum infections","volume":"7","author":"Felger","year":"2012","journal-title":"PLoS ONE"},{"key":"B62","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1016\/S1097-2765(05)00077-8","article-title":"Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance","volume":"6","author":"Fidock","year":"2000","journal-title":"Mol. Cell"},{"key":"B63","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1038\/nri2394","article-title":"The X-files in immunity: sex-based differences predispose immune responses","volume":"8","author":"Fish","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"6300","DOI":"10.1128\/IAI.72.11.6300-6305.2004","article-title":"Strain-specific humoral response to a polymorphic malaria vaccine","volume":"72","author":"Fluck","year":"2004","journal-title":"Infect. Immun."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1016\/j.ijpara.2008.01.010","article-title":"Frequent recombination events generate diversity within the multi-copy variant antigen gene families of Plasmodium falciparum","volume":"38","author":"Frank","year":"2008","journal-title":"Int. J. Parasitol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.3389\/fimmu.2018.02769","article-title":"Novel strategies for malaria vaccine design","volume":"9","author":"Frimpong","year":"2018","journal-title":"Front. Immunol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"e3000490","DOI":"10.1371\/journal.pbio.3000490","article-title":"Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of P. falciparum malaria in humans","volume":"17","author":"Galaway","year":"2019","journal-title":"PLOS Biol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"171780","DOI":"10.1098\/rsos.171780","article-title":"The polyphyly of Plasmodium: comprehensive phylogenetic analyses of the malaria parasites (order Haemosporida) reveal widespread taxonomic conflict","volume":"5","author":"Galen","year":"2018","journal-title":"R Soc. Open Sci."},{"key":"B69","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1093\/bfgp\/elz013","article-title":"Functional genomics of simian malaria parasites and host-parasite interactions","volume":"18","author":"Galinski","year":"2019","journal-title":"Brief. Funct. Genomics"},{"key":"B70","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1017\/S0031182017001135","article-title":"Plasmodium knowlesi: a superb in vivo nonhuman primate model of antigenic variation in malaria","volume":"145","author":"Galinski","year":"2018","journal-title":"Parasitology"},{"key":"B71","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1038\/nature01097","article-title":"Genome sequence of the human malaria parasite Plasmodium falciparum","volume":"419","author":"Gardner","year":"2002","journal-title":"Nature"},{"key":"B72","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00436-018-6127-9","article-title":"Plasmodium genomics: an approach for learning about and ending human malaria","volume":"118","author":"Garrido-Cardenas","year":"2019","journal-title":"Parasitol. Res."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1038\/s41564-019-0474-x","article-title":"Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions","volume":"4","author":"Georgiadou","year":"2019","journal-title":"Nat. Microbiol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1111\/bjh.14886","article-title":"The role of the red blood cell in host defence against falciparum malaria: an expanding repertoire of evolutionary alterations","volume":"179","author":"Goheen","year":"2017","journal-title":"Br. J. Haematol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"4856","DOI":"10.1038\/s41467-019-12829-8","article-title":"Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations","volume":"10","author":"Grajcarek","year":"2019","journal-title":"Nat. Commun."},{"key":"B76","doi-asserted-by":"publisher","first-page":"2546","DOI":"10.1016\/j.vaccine.2016.04.019","article-title":"Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1\/AS02A vaccine candidate","volume":"34","author":"Graves","year":"2016","journal-title":"Vaccine"},{"key":"B77","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.zool.2016.06.010","article-title":"Current analysis of host-parasite interactions with a focus on next generation sequencing data","volume":"119","author":"Greenwood","year":"2016","journal-title":"Zoology"},{"key":"B78","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/S1473-3099(10)70166-3","article-title":"Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes","volume":"10","author":"Halstead","year":"2010","journal-title":"Lancet Infect. Dis."},{"key":"B79","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1186\/1475-2875-11-349","article-title":"Resistance to malaria in humans: the impact of strong, recent selection","volume":"11","author":"Hedrick","year":"2012","journal-title":"Malar. J."},{"key":"B80","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/0166-6851(88)90040-0","article-title":"Two approximately 300 kilodalton Plasmodium falciparum proteins at the surface membrane of infected erythrocytes","volume":"27","author":"Howard","year":"1988","journal-title":"Mol. Biochem. Parasitol."},{"key":"B81","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/bs.apar.2015.02.004","article-title":"PfEMP1 - a parasite protein family of key importance in Plasmodium falciparum Malaria immunity and pathogenesis","volume":"88","author":"Hviid","year":"2015","journal-title":"Adv. Parasitol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"16786","DOI":"10.1073\/pnas.1204945109","article-title":"Evidence for additive and interaction effects of host genotype and infection in malaria","volume":"109","author":"Idaghdour","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B83","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1098\/rspb.2001.1903","article-title":"A large gene family for putative variant antigens shared by human and rodent malaria parasites","volume":"269","author":"Janssen","year":"2002","journal-title":"Proc. Biol. Sci."},{"key":"B84","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1038\/ng1931","article-title":"Genome variation and evolution of the malaria parasite Plasmodium falciparum","volume":"39","author":"Jeffares","year":"2007","journal-title":"Nat. Genet."},{"key":"B85","doi-asserted-by":"publisher","first-page":"663","DOI":"10.2217\/fmb.10.21","article-title":"Small variant surface antigens and Plasmodium evasion of immunity","volume":"5","author":"Jemmely","year":"2010","journal-title":"Fut. Microbiol."},{"key":"B86","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1111\/imr.12807","article-title":"Cerebral Plasmodium falciparum malaria: the role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it","volume":"293","author":"Jensen","year":"2020","journal-title":"Immunol. Rev."},{"key":"B87","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/nrmicro3519","article-title":"Sexual development in Plasmodium parasites: knowing when it's time to commit","volume":"13","author":"Josling","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"B88","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1126\/science.1081449","article-title":"Early origin and recent expansion of Plasmodium falciparum","volume":"300","author":"Joy","year":"2003","journal-title":"Science"},{"key":"B89","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1093\/molbev\/msn073","article-title":"Local adaptation and vector-mediated population structure in Plasmodium vivax malaria","volume":"25","author":"Joy","year":"2008","journal-title":"Mol. Biol. Evol."},{"key":"B90","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1007\/s00439-020-02142-6","article-title":"Human genetics and malaria resistance","volume":"139","author":"Kariuki","year":"2020","journal-title":"Hum. Genet"},{"key":"B91","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s13073-016-0343-7","article-title":"Recent advances in malaria genomics and epigenomics","volume":"8","author":"Kirchner","year":"2016","journal-title":"Genome Med."},{"key":"B92","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.pt.2020.03.008","article-title":"Vive la diff\u00e9rence: exploiting the differences between rodent and human malarias","volume":"36","author":"Kirkman","year":"2020","journal-title":"Trends Parasitol."},{"key":"B93","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1093\/nar\/gkt881","article-title":"Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity","volume":"42","author":"Kirkman","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"B94","doi-asserted-by":"publisher","first-page":"e00514","DOI":"10.1128\/mBio.00514-16","article-title":"RTS,S malaria vaccine and increased mortality in girls","volume":"7","author":"Klein","year":"2016","journal-title":"MBio"},{"key":"B95","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1111\/j.1365-3156.2006.01618.x","article-title":"Seasonal variation and high multiplicity of first Plasmodium falciparum infections in children from a holoendemic area in Ghana, West Africa","volume":"11","author":"Kobbe","year":"2006","journal-title":"Trop. Med. Int. Health"},{"key":"B96","doi-asserted-by":"publisher","first-page":"e44","DOI":"10.1371\/journal.ppat.0010044","article-title":"A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes","volume":"1","author":"Kooij","year":"2005","journal-title":"PLoS Pathog."},{"key":"B97","doi-asserted-by":"publisher","first-page":"11068","DOI":"10.1038\/s41598-020-68082-3","article-title":"Plasmodium spp. mixed infection leading to severe malaria: a systematic review and meta-analysis","volume":"10","author":"Kotepui","year":"2020","journal-title":"Sci. Rep."},{"key":"B98","doi-asserted-by":"publisher","first-page":"e1000765","DOI":"10.1371\/journal.ppat.1000765","article-title":"On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from bonobos","volume":"6","author":"Krief","year":"2010","journal-title":"PLoS Pathog."},{"key":"B99","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1086\/432519","article-title":"How malaria has affected the human genome and what human genetics can teach us about malaria","volume":"77","author":"Kwiatkowski","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"B100","doi-asserted-by":"publisher","first-page":"14119","DOI":"10.1073\/pnas.1900147116","article-title":"Chemical depletion of phagocytic immune cells in Anopheles gambiae reveals dual roles of mosquito hemocytes in anti-Plasmodium immunity","volume":"116","author":"Kwon","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B101","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.actatropica.2011.04.020","article-title":"Plasmodium berghei NK65 induces cerebral leukocyte recruitment in vivo: an intravital microscopic study","volume":"120","author":"Lacerda-Queiroz","year":"2011","journal-title":"Acta Trop."},{"key":"B102","doi-asserted-by":"publisher","first-page":"10438","DOI":"10.1038\/s41598-017-10776-2","article-title":"Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model","volume":"7","author":"Lacerda-Queiroz","year":"2017","journal-title":"Sci. Rep."},{"key":"B103","doi-asserted-by":"publisher","first-page":"3088","DOI":"10.3389\/fimmu.2018.03088","article-title":"Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG","volume":"9","author":"Larsen","year":"2018","journal-title":"Front. Immunol."},{"key":"B104","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1146\/annurev-micro-090817-062427","article-title":"The promise of a malaria vaccine-are we closer?","volume":"72","author":"Laurens","year":"2018","journal-title":"Annu. Rev. Microbiol."},{"key":"B105","doi-asserted-by":"publisher","first-page":"e0173294","DOI":"10.1371\/journal.pone.0173294","article-title":"Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine","volume":"12","author":"Laurens","year":"2017","journal-title":"PLoS ONE"},{"key":"B106","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1186\/s12936-015-0814-0","article-title":"De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification","volume":"14","author":"Lauron","year":"2015","journal-title":"Malar. J."},{"key":"B107","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/1471-2164-13-125","article-title":"Characterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS)","volume":"13","author":"Lawton","year":"2012","journal-title":"BMC Genomics"},{"key":"B108","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1128\/MMBR.00059-13","article-title":"DNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum","volume":"78","author":"Lee","year":"2014","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B109","doi-asserted-by":"publisher","first-page":"eaar3619","DOI":"10.1126\/scitranslmed.aar3619","article-title":"Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria","volume":"10","author":"Lee","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"B110","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1038\/nature09442","article-title":"Origin of the human malaria parasite Plasmodium falciparum in gorillas","volume":"467","author":"Liu","year":"2010","journal-title":"Nature"},{"key":"B111","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1038\/s41467-017-01798-5","article-title":"Wild bonobos host geographically restricted malaria parasites including a putative new Laverania species","volume":"8","author":"Liu","year":"2017","journal-title":"Nat. Commun."},{"key":"B112","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.meegid.2015.08.041","article-title":"Do mixed infections matter? Assessing virulence of mixed-clone infections in experimental human and murine malaria","volume":"36","author":"Lover","year":"2015","journal-title":"Infect. Genet. Evol."},{"key":"B113","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.brainresbull.2019.01.010","article-title":"Cerebral malaria","volume":"145","author":"Luzolo","year":"2019","journal-title":"Brain Res. Bull."},{"key":"B114","doi-asserted-by":"publisher","first-page":"296","DOI":"10.3389\/fimmu.2018.00296","article-title":"Integrative approaches to understand the mastery in manipulation of host cytokine networks by protozoan parasites with emphasis on Plasmodium and Leishmania species","volume":"9","author":"Mahanta","year":"2018","journal-title":"Front. Immunol."},{"key":"B115","doi-asserted-by":"publisher","first-page":"5732","DOI":"10.1038\/s41467-019-13480-z","article-title":"Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania","volume":"10","year":"2019","journal-title":"Nat. Commun."},{"key":"B116","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.coi.2014.06.004","article-title":"An evolutionary perspective of how infection drives human genome diversity: the case of malaria","volume":"30","author":"Mangano","year":"2014","journal-title":"Curr. Opin. Immunol."},{"key":"B117","doi-asserted-by":"publisher","first-page":"12819","DOI":"10.1073\/pnas.0503819102","article-title":"Evolution of human-chimpanzee differences in malaria susceptibility: relationship to human genetic loss of N-glycolylneuraminic acid","volume":"102","author":"Martin","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S.A."},{"key":"B118","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1017\/S0031182016001335","article-title":"Non-human primate malaria parasites: out of the forest and into the laboratory","volume":"145","author":"Martinelli","year":"2018","journal-title":"Parasitology"},{"key":"B119","doi-asserted-by":"publisher","first-page":"4089","DOI":"10.1128\/AAC.00623-08","article-title":"Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central Africa","volume":"52","author":"McCollum","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"B120","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1097\/QCO.0000000000000065","article-title":"Detecting specific infections in children through host responses: a paradigm shift","volume":"27","author":"Mejias","year":"2014","journal-title":"Curr. Opin. Infect. Dis."},{"key":"B121","doi-asserted-by":"publisher","first-page":"15178","DOI":"10.1073\/pnas.1520426112","article-title":"Plasmodium evasion of mosquito immunity and global malaria transmission: The lock-and-key theory","volume":"112","author":"Molina-Cruz","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B122","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1038\/ng1924","article-title":"Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome","volume":"39","author":"Mu","year":"2007","journal-title":"Nat. Genet"},{"key":"B123","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/nature00836","article-title":"Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum","volume":"418","author":"Mu","year":"2002","journal-title":"Nature"},{"key":"B124","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/S0140-6736(15)00694-7","article-title":"RTS,S\/AS01 malaria vaccine and child mortality","volume":"386","author":"Muller","year":"2015","journal-title":"Lancet"},{"key":"B125","doi-asserted-by":"publisher","first-page":"e1004528","DOI":"10.1371\/journal.ppat.1004528","article-title":"Experimental cerebral malaria pathogenesis\u2013hemodynamics at the blood brain barrier","volume":"10","author":"Nacer","year":"2014","journal-title":"PLoS Pathog."},{"key":"B126","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1093\/molbev\/msi154","article-title":"Evolution of noncoding and silent coding sites in the Plasmodium falciparum and Plasmodium reichenowi genomes","volume":"22","author":"Neafsey","year":"2005","journal-title":"Mol. Biol. Evol."},{"key":"B127","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1056\/NEJMoa1505819","article-title":"Genetic diversity and protective efficacy of the RTS,S\/AS01 malaria vaccine","volume":"373","author":"Neafsey","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"B128","doi-asserted-by":"publisher","first-page":"w20249","DOI":"10.4414\/smw.2020.20249","article-title":"Is antibody-dependent enhancement playing a role in COVID-19 pathogenesis?","volume":"150","author":"Negro","year":"2020","journal-title":"Swiss Med. Wkly."},{"key":"B129","doi-asserted-by":"publisher","first-page":"e1004824","DOI":"10.1371\/journal.pcbi.1004824","article-title":"Inferring strain mixture within clinical Plasmodium falciparum isolates from genomic sequence data","volume":"12","author":"O'Brien","year":"2016","journal-title":"PLoS Comput. Biol."},{"key":"B130","doi-asserted-by":"publisher","first-page":"2344","DOI":"10.1093\/molbev\/msq119","article-title":"Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum","volume":"27","author":"Ochola","year":"2010","journal-title":"Mol. Biol. Evol."},{"key":"B131","doi-asserted-by":"publisher","first-page":"e1000446","DOI":"10.1371\/journal.ppat.1000446","article-title":"A new malaria agent in African hominids","volume":"5","author":"Ollomo","year":"2009","journal-title":"PLoS Pathog."},{"key":"B132","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.1056\/NEJMoa1515257","article-title":"Seven-year efficacy of RTS,S\/AS01 malaria vaccine among young African children","volume":"374","author":"Olotu","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"B133","doi-asserted-by":"publisher","first-page":"7167","DOI":"10.1073\/pnas.0811313106","article-title":"Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence","volume":"106","author":"Otsuki","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B134","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/s12915-014-0086-0","article-title":"A comprehensive evaluation of rodent malaria parasite genomes and gene expression","volume":"12","author":"Otto","year":"","journal-title":"BMC Biol."},{"key":"B135","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/s41564-018-0162-2","article-title":"Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria","volume":"3","author":"Otto","year":"2018","journal-title":"Nat. Microbiol."},{"key":"B136","doi-asserted-by":"publisher","first-page":"4754","DOI":"10.1038\/ncomms5754","article-title":"Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts","volume":"5","author":"Otto","year":"","journal-title":"Nat. Commun."},{"key":"B137","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1186\/1475-2875-9-175","article-title":"Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine","volume":"9","author":"Ouattara","year":"2010","journal-title":"Malar. J."},{"key":"B138","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1038\/nature07306","article-title":"The genome of the simian and human malaria parasite Plasmodium knowlesi","volume":"455","author":"Pain","year":"2008","journal-title":"Nature"},{"key":"B139","doi-asserted-by":"publisher","first-page":"42","DOI":"10.12688\/wellcomeopenres.11864.1","article-title":"An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion","volume":"2","author":"Pasini","year":"2017","journal-title":"Wellcome Open Res."},{"key":"B140","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1016\/j.molbiopara.2007.10.011","article-title":"Congenicity and genetic polymorphism in cloned lines derived from a single isolate of a rodent malaria parasite","volume":"157","author":"Pattaradilokrat","year":"2008","journal-title":"Mol. Biochem. Parasitol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"7161","DOI":"10.1073\/pnas.0811430106","article-title":"Gene encoding erythrocyte binding ligand linked to blood stage multiplication rate phenotype in Plasmodium yoelii yoelii","volume":"106","author":"Pattaradilokrat","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B142","doi-asserted-by":"publisher","first-page":"e02995","DOI":"10.1128\/mBio.02995-19","article-title":"Plasmodium yoelii erythrocyte-binding-like protein modulates host cell membrane structure, immunity, and disease severity","volume":"11","author":"Peng","year":"2020","journal-title":"MBio"},{"key":"B143","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.meegid.2006.04.005","article-title":"The phylogeny of rodent malaria parasites: simultaneous analysis across three genomes","volume":"7","author":"Perkins","year":"2007","journal-title":"Infect. Genet. Evol."},{"key":"B144","doi-asserted-by":"publisher","first-page":"10689","DOI":"10.1073\/pnas.162349899","article-title":"High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers","volume":"99","author":"Peters","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B145","doi-asserted-by":"publisher","first-page":"3018","DOI":"10.1073\/pnas.87.8.3018","article-title":"Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria","volume":"87","author":"Peterson","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B146","doi-asserted-by":"publisher","first-page":"3269","DOI":"10.1093\/gbe\/evz244","article-title":"Ancient introgression between two ape malaria parasite species","volume":"11","author":"Plenderleith","year":"2019","journal-title":"Genome Biol. Evol"},{"key":"B147","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/S0065-3527(08)60268-7","article-title":"Antibody-dependent enhancement of viral infectivity","volume":"31","author":"Porterfield","year":"1986","journal-title":"Adv. Virus Res."},{"key":"B148","doi-asserted-by":"publisher","first-page":"4512","DOI":"10.1038\/s41467-019-12294-3","article-title":"Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand","volume":"10","author":"Proto","year":"2019","journal-title":"Nat. Commun."},{"key":"B149","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1073\/pnas.0914440107","article-title":"African great apes are natural hosts of multiple related malaria species, including Plasmodium falciparum","volume":"107","author":"Prugnolle","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B150","doi-asserted-by":"publisher","first-page":"e01046","DOI":"10.1128\/JCM.01046-18","article-title":"Effect of vaccination on Pneumococci isolated from the nasopharynx of healthy children and the middle ear of children with otitis media in Iceland","volume":"56","author":"Quirk","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"B151","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1186\/1471-2148-12-219","article-title":"Molecular evolution and phylogenetics of rodent malaria parasites","volume":"12","author":"Ramiro","year":"2012","journal-title":"BMC Evol. Biol."},{"key":"B152","doi-asserted-by":"publisher","first-page":"103","DOI":"10.4269\/ajtmh.1999.61.103","article-title":"Genetic polymorphism of falciparum malaria vaccine candidate antigen genes among field isolates in India","volume":"61","author":"Ranjit","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"B153","doi-asserted-by":"publisher","first-page":"e1000933","DOI":"10.1371\/journal.pcbi.1000933","article-title":"Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes\u2013divide and conquer","volume":"6","author":"Rask","year":"2010","journal-title":"PLoS Comput. Biol."},{"key":"B154","doi-asserted-by":"publisher","first-page":"e1007172","DOI":"10.1371\/journal.pgen.1007172","article-title":"Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania","volume":"14","author":"Ravenhall","year":"2018","journal-title":"PLoS Genet."},{"key":"B155","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.pt.2011.01.006","article-title":"A plethora of Plasmodium species in wild apes: a source of human infection?","volume":"27","author":"Rayner","year":"2011","journal-title":"Trends Parasitol."},{"key":"B156","doi-asserted-by":"publisher","first-page":"e1001306","DOI":"10.1371\/journal.ppat.1001306","article-title":"Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern","volume":"7","author":"Recker","year":"2011","journal-title":"PLoS Pathog."},{"key":"B157","first-page":"207","article-title":"Uber das vorkormmen der malaiaparasiten des menschen bei den Afrikanischen menschenaffen","volume":"85","author":"Reichenow","year":"1920","journal-title":"Ventralbl. Bakteriol. Parasitenkd. Intekionskr. Hyg. Abt."},{"key":"B158","doi-asserted-by":"publisher","first-page":"S57","DOI":"10.1017\/S0031182014001528","article-title":"Large, rapidly evolving gene families are at the forefront of host-parasite interactions in Apicomplexa","volume":"142","author":"Reid","year":"2015","journal-title":"Parasitology"},{"key":"B159","doi-asserted-by":"publisher","first-page":"14902","DOI":"10.1073\/pnas.0907740106","article-title":"The origin of malignant malaria","volume":"106","author":"Rich","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B160","doi-asserted-by":"publisher","first-page":"4425","DOI":"10.1073\/pnas.95.8.4425","article-title":"Malaria's Eve: evidence of a recent population bottleneck throughout the world populations of Plasmodium falciparum","volume":"95","author":"Rich","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B161","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/S0167-5699(99)01456-5","article-title":"Is T-cell priming required for initiation of pathology in malaria infections?","volume":"20","author":"Riley","year":"1999","journal-title":"Immunol. Today"},{"key":"B162","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1126\/science.1098876","article-title":"Intercontinental spread of pyrimethamine-resistant malaria","volume":"305","author":"Roper","year":"2004","journal-title":"Science"},{"key":"B163","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1186\/1471-2180-13-244","article-title":"Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population","volume":"13","author":"Rorick","year":"2013","journal-title":"BMC Microbiol."},{"key":"B164","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0140-6736(15)60721-8","article-title":"Efficacy and safety of RTS,S\/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial","volume":"386","author":"Rts","year":"2015","journal-title":"Lancet"},{"key":"B165","doi-asserted-by":"publisher","first-page":"2284","DOI":"10.1056\/NEJMoa1208394","article-title":"A phase 3 trial of RTS,S\/AS01 malaria vaccine in African infants","volume":"367","author":"Rts","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"B166","doi-asserted-by":"publisher","first-page":"1863","DOI":"10.1056\/NEJMoa1102287","article-title":"First results of phase 3 trial of RTS,S\/AS01 malaria vaccine in African children","volume":"365","author":"Rts","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"B167","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1038\/nature21038","article-title":"Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution","volume":"542","author":"Rutledge","year":"2017","journal-title":"Nature"},{"key":"B168","doi-asserted-by":"publisher","first-page":"11810","DOI":"10.1038\/s41598-017-11814-9","article-title":"Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda","volume":"7","author":"Ruybal-Pesantez","year":"2017","journal-title":"Sci. Rep."},{"key":"B169","doi-asserted-by":"publisher","first-page":"4259","DOI":"10.1016\/j.jmb.2019.05.018","article-title":"Blood-stage malaria parasite antigens: structure, function, and vaccine potential","volume":"431","author":"Salinas","year":"2019","journal-title":"J. Mol. Biol."},{"key":"B170","doi-asserted-by":"publisher","first-page":"17415","DOI":"10.1073\/pnas.1311016110","article-title":"High diversity of West African bat malaria parasites and a tight link with rodent Plasmodium taxa","volume":"110","author":"Schaer","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B171","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1126\/science.7112113","article-title":"Lizards infected with malaria: physiological and behavioral consequences","volume":"217","author":"Schall","year":"1982","journal-title":"Science"},{"key":"B172","doi-asserted-by":"publisher","first-page":"2397","DOI":"10.1098\/rspb.2005.3232","article-title":"Rodent malaria parasites Plasmodium chabaudi and P. vinckei do not increase their rates of gametocytogenesis in response to mosquito probing","volume":"272","author":"Shutler","year":"2005","journal-title":"Proc. Biol. Sci."},{"key":"B173","doi-asserted-by":"publisher","first-page":"e03272","DOI":"10.1128\/mBio.03272-19","article-title":"Evolution of host specificity by malaria parasites through altered mechanisms controlling genome maintenance","volume":"11","author":"Siao","year":"2020","journal-title":"mBio"},{"key":"B174","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0092-8674(95)90056-X","article-title":"Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes","volume":"82","author":"Smith","year":"1995","journal-title":"Cell"},{"key":"B175","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1111\/cmi.12183","article-title":"Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes","volume":"15","author":"Smith","year":"2013","journal-title":"Cell. Microbiol."},{"key":"B176","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nature12231","article-title":"Vector transmission regulates immune control of Plasmodium virulence","volume":"498","author":"Spence","year":"2013","journal-title":"Nature"},{"key":"B177","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.pt.2018.11.003","article-title":"Two-faced immunity? The evidence for antibody enhancement of malaria transmission","volume":"35","author":"Stone","year":"2019","journal-title":"Trends Parasitol."},{"key":"B178","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1038\/s41467-017-02646-2","article-title":"Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity","volume":"9","author":"Stone","year":"2018","journal-title":"Nat. Commun."},{"key":"B179","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1016\/S1286-4579(03)00173-4","article-title":"The \u201cMalaria's Eve\u201d hypothesis and the debate concerning the origin of the human malaria parasite Plasmodium falciparum","volume":"5","author":"Su","year":"2003","journal-title":"Microbes Infect."},{"key":"B180","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0092-8674(95)90055-1","article-title":"The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes","volume":"82","author":"Su","year":"1995","journal-title":"Cell"},{"key":"B181","doi-asserted-by":"publisher","first-page":"e00019","DOI":"10.1128\/CMR.00019-19","article-title":"Plasmodium genomics and genetics: new insights into malaria pathogenesis, drug resistance, epidemiology, and evolution","volume":"32","author":"Su","year":"2019","journal-title":"Clin. Microbiol. Rev."},{"key":"B182","doi-asserted-by":"publisher","first-page":"11078","DOI":"10.1038\/ncomms11078","article-title":"Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria","volume":"7","author":"Sundararaman","year":"2016","journal-title":"Nat. Commun."},{"key":"B183","doi-asserted-by":"publisher","first-page":"1544","DOI":"10.1086\/652240","article-title":"Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally","volume":"201","author":"Sutherland","year":"2010","journal-title":"J. Infect. Dis."},{"key":"B184","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1182\/blood.V99.8.2677","article-title":"Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion","volume":"99","author":"Swardson-Olver","year":"2002","journal-title":"Blood"},{"key":"B185","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s12916-017-0906-5","article-title":"Clinical and laboratory predictors of death in African children with features of severe malaria: a systematic review and meta-analysis","volume":"15","author":"Sypniewska","year":"2017","journal-title":"BMC Med."},{"key":"B186","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.parint.2013.09.011","article-title":"Plasmodium falciparum: genetic diversity and complexity of infections in an isolated village in western Thailand","volume":"64","author":"Tanabe","year":"2015","journal-title":"Parasitol. Int."},{"key":"B187","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1016\/j.bbadis.2017.10.023","article-title":"Metabolic modeling helps interpret transcriptomic changes during malaria","author":"Tang","year":"2018","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis. 1864"},{"key":"B188","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1084\/jem.20121130","article-title":"Role of host cell traversal by the malaria sporozoite during liver infection","volume":"210","author":"Tavares","year":"2013","journal-title":"J. Exp. Med."},{"key":"B189","doi-asserted-by":"publisher","first-page":"23230","DOI":"10.1038\/srep23230","article-title":"Ungulate malaria parasites","volume":"6","author":"Templeton","year":"2016","journal-title":"Sci. Rep."},{"key":"B190","doi-asserted-by":"publisher","first-page":"e5568","DOI":"10.1371\/journal.pone.0005568","article-title":"Prospective identification of malaria parasite genes under balancing selection","volume":"4","author":"Tetteh","year":"2009","journal-title":"PLoS ONE"},{"key":"B191","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s12920-019-0599-z","article-title":"Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal","volume":"12","author":"Thiam","year":"2019","journal-title":"BMC Med. Genomics"},{"key":"B192","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1038\/nrg865","article-title":"Genetic analysis of African populations: human evolution and complex disease","volume":"3","author":"Tishkoff","year":"2002","journal-title":"Nat. Rev. Genet"},{"key":"B193","doi-asserted-by":"publisher","first-page":"e2004328","DOI":"10.1371\/journal.pbio.2004328","article-title":"The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes","volume":"16","author":"Tonkin-Hill","year":"2018","journal-title":"PLoS Biol."},{"key":"B194","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1186\/cc2183","article-title":"Clinical review: severe malaria","volume":"7","author":"Trampuz","year":"2003","journal-title":"Crit Care"},{"key":"B195","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.molbiopara.2006.03.012","article-title":"Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria","volume":"148","author":"Trimnell","year":"2006","journal-title":"Mol. Biochem. Parasitol."},{"key":"B196","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1111\/j.1365-3024.2009.01106.x","article-title":"Genetics of susceptibility to Plasmodium falciparum: from classical malaria resistance genes towards genome-wide association studies","volume":"31","author":"Verra","year":"2009","journal-title":"Parasite Immunol."},{"key":"B197","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.pt.2018.12.005","article-title":"Genomic advances in avian malaria research","volume":"35","author":"Videvall","year":"2019","journal-title":"Trends Parasitol."},{"key":"B198","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/978-1-4939-9550-9_15","article-title":"Development of blood stage malaria vaccines","volume":"2013","author":"Vijayan","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"B199","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1126\/science.1059878","article-title":"Recent origin of Plasmodium falciparum from a single progenitor","volume":"293","author":"Volkman","year":"2001","journal-title":"Science"},{"key":"B200","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1038\/ng1930","article-title":"A genome-wide map of diversity in Plasmodium falciparum","volume":"39","author":"Volkman","year":"2007","journal-title":"Nat. Genet."},{"key":"B201","doi-asserted-by":"publisher","first-page":"29201","DOI":"10.1093\/infdis\/jiz618","article-title":"Antibody-dependent enhancement of severe disease is mediated by serum viral load in pediatric dengue virus infections","volume":"6","author":"Waggoner","year":"2020","journal-title":"J. Infect. Dis."},{"key":"B202","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/nrmicro.2017.47","article-title":"Variant surface antigens of Plasmodium falciparum and their roles in severe malaria","volume":"15","author":"Wahlgren","year":"2017","journal-title":"Nat. Rev. Microbiol"},{"key":"B203","doi-asserted-by":"publisher","first-page":"e02015","DOI":"10.1128\/JVI.02015-19","article-title":"Molecular mechanism for antibody-dependent enhancement of coronavirus entry","volume":"94","author":"Wan","year":"2020","journal-title":"J. Virol."},{"key":"B204","doi-asserted-by":"publisher","first-page":"20735","DOI":"10.1073\/pnas.1320771110","article-title":"RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum","volume":"110","author":"Wanaguru","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B205","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1124\/jpet.118.253617","article-title":"Antibody dependent enhancement of Acinetobacter baumannii infection in a mouse pneumonia model","volume":"368","author":"Wang-Lin","year":"2019","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"B206","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.pt.2010.04.002","article-title":"Detecting signatures of balancing selection to identify targets of anti-parasite immunity","volume":"26","author":"Weedall","year":"2010","journal-title":"Trends Parasitol."},{"key":"B207","unstructured":"World Malaria Report 20192019"},{"key":"B208","doi-asserted-by":"publisher","first-page":"15194","DOI":"10.1073\/pnas.1821317116","article-title":"Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics","volume":"116","author":"Winarski","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B209","doi-asserted-by":"crossref","first-page":"15","DOI":"10.21307\/immunohematology-2019-387","article-title":"Expression of Duffy antigen receptor for chemokines during reticulocyte maturation: using a CD71 flow cytometric technique to identify reticulocytes","volume":"21","author":"Woolley","year":"2005","journal-title":"Immunohematology"},{"key":"B210","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1038\/nature00813","article-title":"Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum","volume":"418","author":"Wootton","year":"2002","journal-title":"Nature"},{"key":"B211","doi-asserted-by":"publisher","first-page":"3576","DOI":"10.1016\/j.vaccine.2016.10.047","article-title":"Malaria vaccine: WHO position paper, January 2016 - recommendations","volume":"36","year":"2018","journal-title":"Vaccine"},{"key":"B212","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.celrep.2015.06.058","article-title":"Genome-wide analysis of host-Plasmodium yoelii interactions reveals regulators of the type i interferon response","volume":"12","author":"Wu","year":"2015","journal-title":"Cell Rep."},{"key":"B213","doi-asserted-by":"publisher","first-page":"E511","DOI":"10.1073\/pnas.1316467111","article-title":"Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality","volume":"111","author":"Wu","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B214","doi-asserted-by":"publisher","first-page":"16567","DOI":"10.1073\/pnas.2004332117","article-title":"The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation","volume":"117","author":"Wu","year":"2020","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B215","doi-asserted-by":"publisher","first-page":"e26960","DOI":"10.1371\/journal.pone.0026960","article-title":"Computational prediction of host-parasite protein interactions between P. falciparum and H. sapiens","volume":"6","author":"Wuchty","year":"2011","journal-title":"PLoS ONE"},{"key":"B216","doi-asserted-by":"publisher","first-page":"15280","DOI":"10.1038\/s41598-018-33599-1","article-title":"Detection of host pathways universally inhibited after Plasmodium yoelii infection for immune intervention","volume":"8","author":"Xia","year":"2018","journal-title":"Sci. Rep."},{"key":"B217","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.ijpara.2019.04.003","article-title":"Generation and functional characterisation of Plasmodium yoelii csp deletion mutants using a microhomology-based CRISPR\/Cas9 method","volume":"49","author":"Xu","year":"2019","journal-title":"Int. J. Parasitol."},{"key":"B218","doi-asserted-by":"publisher","first-page":"23449","DOI":"10.1038\/srep23449","article-title":"Characterization of the Plasmodium interspersed repeats (PIR) proteins of Plasmodium chabaudi indicates functional diversity","volume":"6","author":"Yam","year":"2016","journal-title":"Sci. Rep."},{"key":"B219","doi-asserted-by":"publisher","first-page":"2498","DOI":"10.1039\/C7MB00502D","article-title":"Host immune evasion strategies of malaria blood stage parasite","volume":"13","author":"Yam","year":"2017","journal-title":"Mol. Biosyst."},{"key":"B220","doi-asserted-by":"publisher","first-page":"e3000271","DOI":"10.1371\/journal.pbio.3000271","article-title":"Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum","volume":"17","author":"Zhang","year":"2019","journal-title":"PLoS Biol."},{"key":"B221","doi-asserted-by":"publisher","first-page":"e40845","DOI":"10.7554\/eLife.40845","article-title":"The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria","volume":"8","author":"Zhu","year":"2019","journal-title":"Elife"}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2020.587933\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T21:46:29Z","timestamp":1669326389000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2020.587933\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,27]]},"references-count":221,"alternative-id":["10.3389\/fcimb.2020.587933"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2020.587933","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,27]]},"article-number":"587933"}}