{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T06:15:18Z","timestamp":1764828918155,"version":"3.41.2"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T00:00:00Z","timestamp":1634774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p><jats:italic>Toxoplasma gondii<\/jats:italic> is a worldwide zoonotic protozoan. Donkeys are often susceptible to many pathological agents, acting as carriers of pathogens for other animal species and humans. However, data on the prevalence of <jats:italic>T. gondii<\/jats:italic> in donkeys during lactation and on the status of antibodies against <jats:italic>T. gondii<\/jats:italic> in donkey milk are lacking. A cross-sectional study evaluated the variation of the anti-<jats:italic>T. gondii<\/jats:italic> antibodies in the blood and milk of domestic donkeys during lactation. A total of 418 domestic donkeys were randomly selected from the Shandong province, eastern China from January 2019 to March 2020. The anti-<jats:italic>T. gondii<\/jats:italic> antibodies were found in 11.72% (49\/418) serum and 9.81% (41\/418) milk samples using a commercial ELISA kit, respectively. There was a very high consistency between the serum and milk (Spearman\u2019s coefficient = 0.858, <jats:italic>p<\/jats:italic>-value &amp;lt; 0.0001 and Kendall\u2019s tau = 0.688, <jats:italic>p<\/jats:italic>-value &amp;lt; 0.0001), particularly at the 45th to 60th day of lactation. The present results of the statistical analysis showed that the history of abortion (<jats:italic>p<\/jats:italic> = 0.026; adjusted OR = 2.20; 95% CI: 1.15\u20134.20) and cat in the house (<jats:italic>p<\/jats:italic> = 0.008; adjusted OR = 2.36; 95% CI: 1.26\u20134.44) were significantly associated with <jats:italic>T. gondii<\/jats:italic> infection in the domestic donkeys. This is the first report to detect antibodies against <jats:italic>T. gondii<\/jats:italic> in donkey milk in China. These results indicate a potential risk of humans contracting the infection through the consumption of raw milk from the naturally infected donkeys.<\/jats:p>","DOI":"10.3389\/fcimb.2021.760400","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T06:16:56Z","timestamp":1634797016000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Detection of Specific IgG-Antibodies Against Toxoplasma gondii in the Serum and Milk of Domestic Donkeys During Lactation in China: A Potential Public Health Concern"],"prefix":"10.3389","volume":"11","author":[{"given":"Long","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-Jian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Feng","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,10,21]]},"reference":[{"key":"B1","first-page":"561","article-title":"Naturally Occurring Toxoplasma Antibodies in Serum and Milk of Lactating Women","volume":"22","author":"Azab","year":"1992","journal-title":"J. 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