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Cell. Infect. Microbiol."],"abstract":"<jats:p><jats:italic>Cryptococcus<\/jats:italic> is an invasive fungus that seriously endangers human life and health, with a complex and well-established immune-escaping mechanism that interferes with the function of the host immune system. <jats:italic>Cryptococcus<\/jats:italic> can attenuate the host\u2019s correct recognition of the fungal antigen and escape the immune response mediated by host phagocytes, innate lymphoid cells, T lymphocytes, B lymphocytes with antibodies, and peripheral cytokines. In addition, the capsule, melanin, dormancy, Titan cells, biofilm, and other related structures of <jats:italic>Cryptococcus<\/jats:italic> are also involved in the process of escaping the host\u2019s immunity, as well as enhancing the ability of <jats:italic>Cryptococcus<\/jats:italic> to infect the host.<\/jats:p>","DOI":"10.3389\/fcimb.2022.1041036","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T06:25:33Z","timestamp":1665642333000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":41,"title":["Cryptococcus escapes host immunity: What do we know?"],"prefix":"10.3389","volume":"12","author":[{"given":"Chen","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yemei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelei","family":"Zang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengyu","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yitong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingxia","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinying","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1128\/iai.65.2.525-530.1997","article-title":"A role for b cells in resistance to cryptococcus neoformans in mice","volume":"65","author":"Aguirre","year":"1997","journal-title":"Infect. 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