{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:58:51Z","timestamp":1785769131523,"version":"3.56.0"},"reference-count":65,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010751","name":"Fondo Nacional de Desarrollo Cient\u00edfico, Tecnol\u00f3gico y de Innovaci\u00f3n Tecnol\u00f3gica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010751","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010751","name":"Fondo Nacional de Desarrollo Cient\u00edfico, Tecnol\u00f3gico y de Innovaci\u00f3n Tecnol\u00f3gica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010751","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p><jats:italic>Salmonella<\/jats:italic> spp. is a relevant foodborne pathogen with worldwide distribution. To mitigate <jats:italic>Salmonella<\/jats:italic> infections, bacteriophages represent an alternative to antimicrobials and chemicals in food animals and food in general. Bacteriophages (phages) are viruses that infect bacteria, which interact constantly with their host. Importantly, the study of these interactions is crucial for the use of phages as a mitigation strategy. In this study, experimental coevolution of <jats:italic>Salmonella<\/jats:italic> Enteritidis (<jats:italic>S<\/jats:italic>. Enteritidis) and a lytic phage was conducted in tryptic soy broth for 21 days. Transfer to fresh media was conducted daily and every 24 hours, 2 mL of the sample was collected to quantify <jats:italic>Salmonella<\/jats:italic> OD<jats:sub>600<\/jats:sub> and phage titter. Additionally, time-shift experiments were conducted on 20 colonies selected on days 1, 12, and 21 to evaluate the evolution of resistance to past (day 1), present (day 12), and future (day 21) phage populations. The behavior of the dynamics was modeled and simulated with mathematical mass-action models. Bacteria and phage from days 1 and 21 were sequenced to determine the emergence of mutations. We found that <jats:italic>S<\/jats:italic>. Enteritidis grew for 21 days in the presence and absence of the phage and developed resistance to the phage from day 1. Also, the phage was also able to survive in the media for 21 days, however, the phage titer decreased in approx. 3 logs PFU\/mL. The stability of the lytic phage population was consistent with the leaky resistance model. The time-shift experiments showed resistance to phages from day 1 of at least 85% to the past, present, and future phages. Sequencing of <jats:italic>S<\/jats:italic>. Enteritidis showed mutations in genes involved in lipopolysaccharide biosynthesis genes <jats:italic>rfbP<\/jats:italic> and <jats:italic>rfbN<\/jats:italic> at day 21. The phage showed mutations in the tail phage proteins responsible for recognizing the cell surface receptors. These results suggest that interactions between bacteria and phage in a rich resource media generate a rapid resistance to the infective phage but a fraction of the population remains susceptible. Interactions between <jats:italic>Salmonella<\/jats:italic> and lytic phages are an important component for the rational use of phages to control this important foodborne pathogen.<\/jats:p>","DOI":"10.3389\/fcimb.2022.897171","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T07:28:00Z","timestamp":1654068480000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Long-Term Interactions of Salmonella Enteritidis With a Lytic Phage for 21 Days in High Nutrients Media"],"prefix":"10.3389","volume":"12","author":[{"given":"Rocio","family":"Barron-Montenegro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e1cil","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jesus","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana M.","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Benavides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Arredondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisca P.","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Bast\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soledad","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Hamilton-West","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Castro-Nallar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea I.","family":"Moreno-Switt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1662-9","article-title":"Bacterial Biodiversity Drives the Evolution of CRISPR-Based Phage Resistance","volume":"574","author":"Alseth","year":"2019","journal-title":"Nature"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.201400257","article-title":"Biocontrol of Salmonella Enteritidis in Spiked Chicken Cuts by Lytic Bacteriophages \u03a6SP-1 and \u03a6sp-3","volume":"55","author":"Augustine","year":"2015","journal-title":"J. Basic. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"88","DOI":"10.4161\/mge.20031","article-title":"Virus-Host Swinging Party in the Oceans","volume":"2","author":"Avrani","year":"2012","journal-title":"Mobile. Genet. Elements."},{"key":"B4","unstructured":"Fastqc a Quality Control Tool for High Throughput Sequence Data2016"},{"key":"B5","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1007\/s00248-013-0284-2","article-title":"Co-Evolutionary Dynamics of the Bacteria Vibrio sp. CV1 and Phages V1G, V1P1, and V1P2: Implications for Phage Therapy","volume":"66","author":"Barbosa","year":"2013","journal-title":"Microb Ecol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1126\/science.1138140","article-title":"CRISPR Provides Against Viruses in Prokaryotes","volume":"315","author":"Barrangou","year":"2007","journal-title":"Science"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/femsle\/fnw002","article-title":"Host Receptors for Bacteriophage Adsorption","volume":"363","author":"Bertozzi Silva","year":"2016","journal-title":"FEMS Microbiol. Lett."},{"key":"B8","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1046\/j.1461-0248.2000.00161.x","article-title":"Linking Genetic Change to Community Evolution: Insights From Studies of Bacteria and Bacteriophage","volume":"3","author":"Bohannan","year":"2000","journal-title":"Ecol. Lett."},{"key":"B9","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: A Flexible Trimmer for Illumina Sequence Data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1073\/pnas.2104592118","article-title":"Coevolutionary Phage Training Leads to Greater Bacterial Suppression and Delays the Evolution of Phage Resistance","volume":"118","author":"Borin","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B11","doi-asserted-by":"publisher","first-page":"8365","DOI":"10.1038\/srep08365","article-title":"RASTtk: A Modular and Extensible Implementation of the RAST Algorithm for Building Custom Annotation Pipelines and Annotating Batches of Genomes","volume":"5","author":"Brettin","year":"2015","journal-title":"Sci. Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.meegid.2007.01.005","article-title":"Experimental Coevolution With Bacteria and Phage. The Pseudomonas fluorescens-\u03a62 model system","volume":"7","author":"Brockhurst","year":"2007","journal-title":"Infect. Genet. Evol."},{"key":"B13","article-title":"Running With the Red Queen: The Role of Biotic Conflicts in Evolution","volume":"281","author":"Brockhurst","year":"2014","journal-title":"Proc. Royal Soc"},{"key":"B14","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1098\/rspb.2001.1945","article-title":"Antagonistic Coevolution Between a Bacterium and Bacteriophage","volume":"269","author":"Buckling","year":"2002","journal-title":"Proc. R. Soc. B."},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.4958","article-title":"D-GENIES: Dot Plot Large Genomes in an Interactive, Efficient and Simple Way","volume":"6","author":"Cabanettes","year":"2018","journal-title":"PeerJ"},{"key":"B16","unstructured":"National Enteric Disease Surveillance: Salmonella Annual Report 20112011"},{"key":"B17","doi-asserted-by":"publisher","first-page":"80","DOI":"10.4161\/fly.19695","article-title":"A Program for Annotating and Predicting the Effects of Single Nucleotide Polymorphisms, SnpEff: SNPs in the Genome of Drosophila Melanogaster Strain W1118; Iso-2; Iso-3","volume":"6","author":"Cingolani","year":"2012","journal-title":"Fly (Austin)"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2005971","article-title":"Leaky Resistance and the Conditions for the Existence of Lytic Bacteriophage","volume":"16","author":"Chaudhry","year":"2018","journal-title":"PLoS Biology"},{"key":"B19","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/1471-0307.12636","article-title":"Salmonella Anatum, S. Infantis and S. Schwarzengrund in Brazilian Cheeses: Occurrence and Antibiotic Resistance Profiles","volume":"73","author":"da Cunha-Neto","year":"2020","journal-title":"Int. J. Dairy. Technol."},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.07.003","article-title":"Salmonella Contamination of Cereal Ingredients for Animal Feeds","volume":"166","author":"Davies","year":"2013","journal-title":"Vet. Microbiol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"103217","DOI":"10.1016\/j.fm.2019.05.001","article-title":"Salmonella Spp. And Escherichia Coli O157:H7 Prevalence and Levels on Lettuce: A Systematic Review and Meta-Analysis","volume":"84","author":"de Oliveira Elias","year":"2019","journal-title":"Food Microbiol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"e00591","DOI":"10.1128\/AEM.00591-19","article-title":"Worldwide Epidemiology of Salmonella Serovars in Animal-Based Foods: A Meta-Analysis","volume":"85","author":"Ferrari","year":"2019","journal-title":"Appl. Environ. Microb."},{"key":"B23","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1089\/phage.2020.0036","article-title":"How Broad Is Enough: The Host Range of Bacteriophages and Its Impact on the Agri-Food Sector","author":"Fong","year":"2020","journal-title":"PHAGE"},{"key":"B24","article-title":"Haplotype-Based Variant Detection From Shrot-Read Sequencing","author":"Garrison","year":"2012"},{"key":"B25","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.ijfoodmicro.2011.12.023","article-title":"Biocontrol of Salmonella Typhimurium in RTE Foods With the Virulent Bacteriophage FO1-E2","volume":"154","author":"Guenther","year":"2012","journal-title":"Int. J. Food Microbiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pmed.1001923","article-title":"World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010","volume":"12","author":"Havelaar","year":"2015","journal-title":"PLoS Med."},{"key":"B27","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1111\/evo.13833","article-title":"Phage Resistance Evolution In Vitro is Not Reflective of in a Plant-Bacteria-Phage System","volume":"73","author":"Hernandez","year":"2019","journal-title":"Evolution"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1186\/1297-9716-42-34","article-title":"Animal Contact as a Source of Human Non-Typhoidal Salmonellosis","volume":"42","author":"Hoelzer","year":"2011","journal-title":"Vet. Res."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/v11020188","article-title":"Host Resistance, Genomics and Population Dynamics in a Salmonella Enteritidis and Phage System","volume":"11","author":"Holgu\u00edn","year":"2019","journal-title":"Viruses"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10408398.2021.1984200","article-title":"A Systematic Review From Basics to Omics on Bacteriophage Applications in Poultry Production and Processing","author":"Islam","year":"2021","journal-title":"Crit. Rev. Food Sci. Nutr"},{"key":"B31","doi-asserted-by":"publisher","first-page":"9","DOI":"10.4315\/0362-028x-73.1.9","article-title":"Control of Salmonella on Sprouting Mung Bean and Alfalfa Seeds by Using a Biocontrol Preparation Based on Antagonistic Bacteria and Lytic Bacteriophages","volume":"73","author":"Jianxiong","year":"2010","journal-title":"J. Food Prot."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.01.014","article-title":"Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria","volume":"25","author":"Kortright","year":"2019","journal-title":"Cell Host Microbe"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6976.12072","article-title":"Bacteria-Phage Coevolution as a Driver of Ecological and Evolutionary Processes in Microbial Communities","volume":"38","author":"Koskella","year":"2014","journal-title":"FEMS Microbiol. Rev."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2315","article-title":"Bacteriophage Resistance Mechanisms","volume":"8","author":"Labrie","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923","article-title":"Fast Gapped-Read Alignment With Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"B36","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1086\/284364","article-title":"Constraints on the Coevolution of Bacteria and Virulent Phage: A Model, Some Experiments, and Predictions for Natural Communities","volume":"125","author":"Lenski","year":"1985","journal-title":"Am. Nat."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-16-336","article-title":"Prevalence and Antimicrobial Resistance of Salmonella in Market Raw Oysters in Taiwan","volume":"80","author":"Lo","year":"2017","journal-title":"J. Food Prot."},{"key":"B38","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1111\/j.1420-9101.2008.01501.x","article-title":"Increasing Productivity Accelerates Host-Parasite Coevolution","volume":"3","author":"Lopez-Pascua","year":"2008","journal-title":"J. Evol. Biol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/femspd\/fty002","article-title":"The CRISPR-Cas System in Enterobacteriaceae","volume":"76","author":"Medina-Aparicio","year":"2018","journal-title":"Pathog. Dis."},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-64.7.927","article-title":"Effect of Phage on Survival of Salmonella Enteritidis During Manufacture and Storage of Cheddar Cheese Made From Raw and Pasteurized Milk","volume":"64","author":"Modi","year":"2001","journal-title":"J. Food Prot."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1128\/AEM.00209-19","article-title":"Determinants of Phage Host Range in Staphylococcus Species","volume":"85","author":"Moller","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1128\/JB.06052-11","article-title":"Functional Characterization of UDP-Glucose:Undecaprenyl-Phosphate Glucose-1-Phosphate Transferases of Escherichia Coli and Caulobacter Crescentus","volume":"194","author":"Patel","year":"2012","journal-title":"J. Bacteriol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/antibiotics9070365","article-title":"Antimicrobial Susceptibility Testing for Salmonella Serovars Isolated From Food Samples: Five-Year Monitoring, (2015\u20132019)","volume":"9","author":"Peruzy","year":"2020","journal-title":"Antibiotics"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2010.05.021","article-title":"Simultaneous Detection of Salmonella Spp., Salmonella Typhi and Salmonella Typhimurium in Sliced Fruits Using Multiplex PCR","volume":"22","author":"Pui","year":"2011","journal-title":"Food Control."},{"key":"B45","doi-asserted-by":"publisher","first-page":"6","DOI":"10.4315\/0362-028X.JFP-15-274","article-title":"Prevalence and Characteristics of Salmonella Serotypes Isolated From Fresh Produce Marketed in the United States","volume":"79","author":"Reddy","year":"2016","journal-title":"J. Food Prot."},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10030606","article-title":"Novel Salmonella Phage, Vb_Sen_STGO-35- 1, Characterization and Evaluation in Chicken Meat","volume":"10","author":"Rivera","year":"2022","journal-title":"Microorganisms"},{"key":"B47","doi-asserted-by":"publisher","first-page":"586","DOI":"10.3390\/v11070586","article-title":"Two Phages of the Genera Felixounavirus Subjected to 12 Hour Challenge on Salmonella Infantis Showed Distinct Genotypic and Phenotypic Changes","volume":"11","author":"Rivera","year":"2019","journal-title":"Viruses"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-17-075","article-title":"Backyard Farms Represent a Source of Wide Host Range Salmonella Phages That Lysed the Most Common Salmonella Serovars","volume":"81","author":"Rivera","year":"2018","journal-title":"J. Food Prot."},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.4315\/jfp-21-096","article-title":"A Review of Significant European Foodborne Outbreaks in the Last Decade","volume":"84","author":"Sarno","year":"2021","journal-title":"J. Food Prot."},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268812000039","article-title":"Prevalence and Antimicrobial Susceptibility of Salmonella in Japanese Broiler Flocks","volume":"140","author":"Sasaki","year":"2012","journal-title":"Epidemiol. Infect."},{"key":"B51","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3201\/eid1701.P11101","article-title":"Foodborne Illness Acquired in the United States-Major Pathogens","volume":"17","author":"Scallan","year":"2011","journal-title":"Emerging. Infect. Dis."},{"key":"B52","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.meegid.2019.05.021","article-title":"Impact of Bile Salts on Coevolutionary Dynamics Between the Gut Bacterium Escherichia Coli and its Lytic Phage PP01","volume":"73","author":"Scanlan","year":"2019","journal-title":"Infect. Genet. Evol."},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1086\/285929","article-title":"Host-Parasite Coexistence: The Role of Spatial Refuges in Stabilizing Bacteria-Phage Interactions","volume":"148","author":"Schrag","year":"1996","journal-title":"Am. Nat"},{"key":"B54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/20905068.2020.1851441","article-title":"A Review of Phage Mediated Antibacterial Applications","volume":"57","author":"Ssekatawa","year":"2021","journal-title":"Alexandria. J. Med."},{"key":"B55","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.ijfoodmicro.2015.04.025","article-title":"Reduction of Salmonella on Chicken Meat and Chicken Skin by Combined or Sequential Application of Lytic Bacteriophage With Chemical Antimicrobials","volume":"207","author":"Sukumaran","year":"2015","journal-title":"Int. J. Food Microbiol."},{"key":"B56","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1086\/282825","article-title":"Partitioning of Resources and the Outcome of Interspecific Competition: A Model and Some General Considerations","volume":"107","author":"Stewart","year":"1973","journal-title":"Am. Nat."},{"key":"B57","doi-asserted-by":"publisher","first-page":"18","DOI":"10.4315\/0362-028X.JFP-12-263","article-title":"Antimicrobial Resistance of Salmonella Enterica Isolates From Bulk Tank Milk and Milk Filters in the United States","volume":"76","author":"Van Kessel","year":"2013","journal-title":"J. Food Prot."},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1111\/jam.13754","article-title":"Phenotypic and Virulence Traits of Escherichia Coli and Salmonella Strains Isolated From Vegetables and Fruits From India","volume":"125","author":"Verma","year":"2018","journal-title":"J. Appl. Microbiol."},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/peu081","article-title":"A Temporal Study of Salmonella Enterica Serotypes From Broiler Farms in Brazil","volume":"94","author":"Voss-Rech","year":"2015","journal-title":"Poultry. Sci."},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2017.194","article-title":"Immune Loss as a Driver of Coexistence During Host-Phage Coevolution","volume":"12","author":"Weissman","year":"2018","journal-title":"ISME. J."},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1038\/ng1202-569","article-title":"Biological and Biomedical Implications of the Co-Evolution of Pathogens and Their Hosts","volume":"32","author":"Woolhouse","year":"2002","journal-title":"Nat. Genet."},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.53853","article-title":"Structural Insights Into Sodium Transport by the Oxaloacetate Decarboxylase Sodium Pump","volume":"9","author":"Xu","year":"2020","journal-title":"eLife"},{"key":"B63","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.ijfoodmicro.2010.04.015","article-title":"Prevalence and Characterization of Salmonella Serovars in Retail Meats of Marketplace in Shaanxi, China","volume":"141","author":"Yang","year":"2010","journal-title":"Int. J. Food Microbiol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.meatsci.2018.01.007","article-title":"Effect of Ultraviolet Light, Organic Acids, and Bacteriophage on Salmonella Populations in Ground Beef","volume":"139","author":"Yeh","year":"2018","journal-title":"Meat. Sci."},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-16-396","article-title":"Prevalence of Salmonella in Cashews, Hazelnuts, Macadamia Nuts, Pecans, Pine Nuts, and Walnuts in the United States","volume":"80","author":"Zhang","year":"2017","journal-title":"J. Food Prot."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2022.897171\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T07:28:06Z","timestamp":1654068486000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2022.897171\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,30]]},"references-count":65,"alternative-id":["10.3389\/fcimb.2022.897171"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2022.897171","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,30]]},"article-number":"897171"}}