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Cell. Infect. Microbiol."],"abstract":"<jats:p>The 6-cysteine protein family is one of the most abundant surface antigens that are expressed throughout the\u00a0<jats:italic>Plasmodium falciparum<\/jats:italic>\u00a0life cycle. Many members of the 6-cysteine family have critical roles in parasite development across the life cycle in parasite transmission, evasion of the host immune response and host cell invasion. The common feature of the family is the 6-cysteine domain, also referred to as s48\/45 domain, which is conserved across Aconoidasida. 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