{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:53:06Z","timestamp":1753890786497,"version":"3.41.2"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p>A 33-year-old male patient with a 17-year Behcet\u2019s syndrome history showed abdominal pain and fever symptoms. The abdominal CT was suggestive of an acute ileocecal intestinal perforation. In addition, the symptoms disappeared after the conservative treatment. Some related examinations, including capsule endoscopy, were performed to explain the phenomenon of the food residue urine. These results indicated the intestine-urinary tract fistula formation, supposed to be the outcome of intestinal Behcet\u2019s syndrome perforation. This is a rare case of intestinal Behcet\u2019s syndrome with abdominal symptoms as the main manifestation. It was complicated by entero-urinary fistula formation and urinary tract infections. Now, we report this story to emphasize that capsule endoscopy is conducive to the diagnosis and assessment of the intestinal Behcet\u2019s syndrome; moreover, anti-inflammatory treatment including biological agents is effective to relieve the disease at the acute stage in addition to surgical methods.<\/jats:p>","DOI":"10.3389\/fcimb.2023.1108247","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T04:35:46Z","timestamp":1680064546000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Intestinal Behcet\u2019s syndrome with an unusual complication bladder-intestines fistula and urinary tract infections\u2014A case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Jiewen","family":"Deng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuanming","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"iii101","DOI":"10.1093\/rheumatology\/kez626","article-title":"Behcet: The syndrome","volume":"59","author":"Bettiol","year":"2020","journal-title":"Rheumatol. (Oxford)."},{"key":"B2","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.clindermatol.2017.06.004","article-title":"Behcet disease: New aspects","volume":"35","author":"Bulur","year":"2017","journal-title":"Clin. Dermatol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1038\/ajg.2009.331","article-title":"Development and validation of novel diagnostic criteria for intestinal behcet's disease in korean patients with ileocolonic ulcers","volume":"104","author":"Cheon","year":"2009","journal-title":"Am. J. Gastroenterol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"e116","DOI":"10.1097\/MCG.0b013e3181c8a50f","article-title":"Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal behcet disease","volume":"44","author":"Chung","year":"2010","journal-title":"J. Clin. Gastroenterol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1080\/1744666X.2016.1205486","article-title":"Behcet's disease: Epidemiology, clinical manifestations, and diagnosis","volume":"13","author":"Davatchi","year":"2017","journal-title":"Expert Rev. Clin. Immunol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"6578","DOI":"10.3748\/wjg.14.6578","article-title":"Colonic perforation in behcet's syndrome","volume":"14","author":"Dowling","year":"2008","journal-title":"World J. Gastroenterol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1053\/gast.2001.22556","article-title":"Anti-tumor necrosis factor monoclonal antibody therapy for gastrointestinal behcet's disease: A case report","volume":"120","author":"Hassard","year":"2001","journal-title":"Gastroenterology."},{"key":"B8","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1136\/annrheumdis-2018-213225","article-title":"Update of the eular recommendations for the management of behcet's syndrome","volume":"77","author":"Hatemi","year":"2018","journal-title":"Ann. Rheum Dis."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003348","article-title":"Characteristics, treatment, and long-term outcome of gastrointestinal involvement in behcet's syndrome: A strobe-compliant observational study from a dedicated multidisciplinary center","volume":"95","author":"Hatemi","year":"2016","journal-title":"Med. (Baltimore)."},{"key":"B10","first-page":"1623","article-title":"[behcet's syndrome]","volume":"140","author":"Jensen","year":"1978","journal-title":"Ugeskr Laeger."},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0190182","article-title":"Cancer risk in korean patients with behcet's disease: A nationwide population-based study","volume":"12","author":"Jung","year":"2017","journal-title":"PloS One"},{"key":"B12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/BF02604297","article-title":"Intestinal involvement in behcet's disease: Review of 136 surgical cases in the japanese literature","volume":"24","author":"Kasahara","year":"1981","journal-title":"Dis. Colon Rectum."},{"key":"B13","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1055\/s-0028-1103481","article-title":"Differential diagnosis of intestinal behcet's disease and crohn's disease by colonoscopic findings","volume":"41","author":"Lee","year":"2009","journal-title":"Endoscopy."},{"key":"B14","doi-asserted-by":"publisher","first-page":"3801","DOI":"10.3748\/wjg.v21.i13.3801","article-title":"Gastrointestinal behcet's disease: A review","volume":"21","author":"Skef","year":"2015","journal-title":"World J. Gastroenterol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1016\/j.cgh.2014.08.042","article-title":"Adalimumab for the treatment of japanese patients with intestinal behcet's disease","volume":"13","author":"Tanida","year":"2015","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s005950300087","article-title":"Sigmoid colon perforation as an unusual complication of behcet's syndrome: Report of a case","volume":"33","author":"Turan","year":"2003","journal-title":"Surg. Today"},{"key":"B17","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.cgh.2014.08.042","article-title":"Adalimumab in the management of behcet's disease","volume":"11","author":"Ueda","year":"2015","journal-title":"Ther. Clin. Risk Manage."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2023.1108247\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T04:35:49Z","timestamp":1680064549000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2023.1108247\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,29]]},"references-count":17,"alternative-id":["10.3389\/fcimb.2023.1108247"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2023.1108247","relation":{},"ISSN":["2235-2988"],"issn-type":[{"type":"electronic","value":"2235-2988"}],"subject":[],"published":{"date-parts":[[2023,3,29]]},"article-number":"1108247"}}