{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T10:35:06Z","timestamp":1793356506615,"version":"4.5.0"},"reference-count":227,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p>\n                    With the widespread use of macrolide antibiotics in China, common pathogens causing children\u2019s infections, such as\n                    <jats:italic>Streptococcus pneumoniae<\/jats:italic>\n                    ,\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    (including\n                    <jats:italic>Group A streptococcus<\/jats:italic>\n                    ,\n                    <jats:italic>Group B streptococcus<\/jats:italic>\n                    ),\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    ,\n                    <jats:italic>Bordetella pertussis<\/jats:italic>\n                    , and\n                    <jats:italic>Mycoplasma pneumoniae<\/jats:italic>\n                    , have shown varying degrees of drug resistance. In order to provide such problem and related evidence for rational use of antibiotics in clinic, we reviewed the drug resistance of common bacteria to macrolides in children recent 20 years.\n                  <\/jats:p>","DOI":"10.3389\/fcimb.2023.1181633","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T11:57:10Z","timestamp":1691668630000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":31,"title":["Severe problem of macrolides resistance to common pathogens in China"],"prefix":"10.3389","volume":"13","author":[{"given":"Jialin","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1093\/jac\/dkq006","article-title":"Molecular characterization of macrolide- and multidrug-resistant Streptococcus pyogenes isolated from adult patients in Barcelona, Spain, (1993-2008)","volume":"65","author":"Ardanuy","year":"2010","journal-title":"J. antimicrobial chemother"},{"key":"B2","first-page":"525","article-title":"Pathogenic spectrum of blood stream infections and realated drug resistance in a grade A territory hospital from 2018 to 2020 (in Chinese)","volume":"42","author":"Bao","year":"2021","journal-title":"Acad. 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