{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:11:46Z","timestamp":1787026306321,"version":"build-2736575974"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p>\n                    Japanese spotted fever (JSF) is caused by\n                    <jats:italic>Rickettsia japonica<\/jats:italic>\n                    , mainly vectored by hard ticks. However, whether\n                    <jats:italic>R. japonica<\/jats:italic>\n                    can be transmitted by other arthropods remains unknown. Moreover, it is of interest to investigate whether other\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species cause spotted fever in endemic areas. In this study, a survey of\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species was performed in hematophagous arthropods (mosquitoes, tabanids, and ticks) from endemic areas for JSF in Hubei Province, central China. The results showed that the diversity and prevalence of\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species in mosquitoes are low, suggesting that mosquitoes may not be the vector of zoonotic\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species. A novel\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species showed a high prevalence (16.31%, 23\/141) in tabanids and was named \u201c\n                    <jats:italic>Candidatus<\/jats:italic>\n                    Rickettsia tabanidii.\u201d It is closely related to\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    from fleas and mosquitoes; however, its pathogenicity in humans needs further investigation. Five\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    species were identified in ticks.\n                    <jats:italic>Rickettsia japonica<\/jats:italic>\n                    , the agent of JSF, was detected only in\n                    <jats:italic>Haemaphysalis longicornis<\/jats:italic>\n                    and\n                    <jats:italic>Haemaphysalis hystricis<\/jats:italic>\n                    , suggesting that they may be the major vectors of\n                    <jats:italic>R. japonica<\/jats:italic>\n                    . Notably, two novel species were identified in\n                    <jats:italic>H. hystricis<\/jats:italic>\n                    ticks, one belonging to the spotted fever group and the other potentially belonging to the ancestral group. The latter one named \u201c\n                    <jats:italic>Candidatus<\/jats:italic>\n                    Rickettsia hubeiensis\u201d may provide valuable insight into the evolutionary history of\n                    <jats:italic>Rickettsia<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.3389\/fcimb.2024.1384284","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:53:02Z","timestamp":1714006382000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Survey of Rickettsia species in hematophagous arthropods from endemic areas for Japanese spotted fever in China"],"prefix":"10.3389","volume":"14","author":[{"given":"Junhua","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1385\/1-59259-192-2:71","article-title":"DNASTAR\u2019s Lasergene sequence analysis software","volume":"132","author":"Burland","year":"2000","journal-title":"Methods Mol. 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