{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T17:00:22Z","timestamp":1788368422562,"version":"build-2803163510"},"reference-count":349,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1P01 AI178377, 1P01 AI179915"],"award-info":[{"award-number":["1P01 AI178377, 1P01 AI179915"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p>Infectious diseases are the leading cause of death in infants and children under 5 years of age. <jats:italic>In utero<\/jats:italic> exposure to viruses can lead to spontaneous abortion, preterm birth, congenital abnormalities or other developmental defects, often resulting in lifelong health sequalae. The underlying biological mechanisms are difficult to study in humans due to ethical concerns and limited sample access. Nonhuman primates (NHP) are closely related to humans, and pregnancy and immune ontogeny in infants are very similar to humans. Therefore, NHP are a highly relevant model for understanding fetal and postnatal virus-host interactions and to define immune mechanisms associated with increased morbidity and mortality in infants. We will discuss NHP models of viruses causing congenital infections, respiratory diseases in early life, and HIV. Cytomegalovirus (CMV) remains the most common cause of congenital defects worldwide. Measles is a vaccine-preventable disease, yet measles cases are resurging. Zika is an example of an emerging arbovirus with devastating consequences for the developing fetus and the surviving infant. Among the respiratory viruses, we will discuss influenza and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We will finish with HIV as an example of a lifelong infection without a cure or vaccine. The review will highlight (i) the impact of viral infections on fetal and infant immune development, (ii) how differences in infant and adult immune responses to infection alter disease outcome, and emphasize the invaluable contribution of pediatric NHP infection models to the design of effective treatment and prevention strategies, including vaccines, for human infants.<\/jats:p>","DOI":"10.3389\/fcimb.2024.1493885","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T06:30:33Z","timestamp":1733207433000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Nonhuman primate models of pediatric viral diseases"],"prefix":"10.3389","volume":"14","author":[{"given":"Vidya","family":"Vijayan K. K.","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"De Paris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1126\/science.aah6157","article-title":"Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys","volume":"353","author":"Abbink","year":"2016","journal-title":"Science."},{"key":"B2","doi-asserted-by":"publisher","first-page":"2","DOI":"10.2174\/157016209787048528","article-title":"The rhesus macaque pediatric SIV infection model - a valuable tool in understanding infant HIV-1 pathogenesis and for designing pediatric HIV-1 prevention strategies","volume":"7","author":"Abel","year":"2009","journal-title":"Curr. HIV Res."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2878","DOI":"10.1128\/JVI.00883-10","article-title":"Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques","volume":"85","author":"Abel","year":"2011","journal-title":"J. Virol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"6357","DOI":"10.1128\/JVI.02240-05","article-title":"Rapid virus dissemination in infant macaques after oral simian immunodeficiency virus exposure in the presence of local innate immune responses","volume":"80","author":"Abel","year":"2006","journal-title":"J. Virol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"6013","DOI":"10.1016\/j.vaccine.2008.07.103","article-title":"A heterologous DNA prime\/protein boost immunization strategy for rhesus cytomegalovirus","volume":"26","author":"Abel","year":"2008","journal-title":"Vaccine."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1038\/nm.4193","article-title":"Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate","volume":"22","author":"Adams Waldorf","year":"2016","journal-title":"Nat. Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1038\/nm.2105","article-title":"A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection","volume":"16","author":"Akahata","year":"2010","journal-title":"Nat. Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1007\/s00296-020-04701-6","article-title":"Kawasaki-like disease in children with COVID-19","volume":"40","author":"Akca","year":"2020","journal-title":"Rheumatol. Int."},{"key":"B9","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/S0022-3476(77)81021-4","article-title":"Persistence of maternal antibody in infants beyond 12 months: mechanism of measles vaccine failure","volume":"91","author":"Albrecht","year":"1977","journal-title":"J. Pediatr."},{"key":"B10","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1034\/j.1600-0684.2003.00024.x","article-title":"Mother-to-infant transmission of SIV via breast-feeding in rhesus macaques","volume":"32","author":"Amedee","year":"2003","journal-title":"J. Med. Primatol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1089\/aid.2017.0169","article-title":"Early sites of virus replication after oral SIV(mac251) infection of infant macaques: implications for pathogenesis","volume":"34","author":"Amedee","year":"2018","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"B12","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1742-4690-1-17","article-title":"Viral and immunological factors associated with breast milk transmission of SIV in rhesus macaques","volume":"1","author":"Amedee","year":"2004","journal-title":"Retrovirology."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2014.0340","article-title":"Systems vaccinology: a promise for the young and the poor","volume":"370","author":"Amenyogbe","year":"2015","journal-title":"Philos. Trans. R Soc. Lond B Biol. Sci."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1007\/s40265-016-0653-5","article-title":"Cytomegalovirus vaccines: current status and future prospects","volume":"76","author":"Anderholm","year":"2016","journal-title":"Drugs."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1056\/NEJMoa2209367","article-title":"Evaluation of mRNA-1273 vaccine in children 6 months to 5 years of age","volume":"387","author":"Anderson","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"252ra120","DOI":"10.1126\/scitranslmed.3008791","article-title":"Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems","volume":"6","author":"Ardeshir","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"B17","doi-asserted-by":"publisher","first-page":"9310","DOI":"10.1128\/JVI.00162-14","article-title":"Limited dissemination and shedding of the UL128 complex-intact, UL\/b\u2019-defective rhesus cytomegalovirus strain 180","volume":"88","author":"Assaf","year":"2014","journal-title":"92. J. Virol."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3390\/v13091878","article-title":"Neonatal development in prenatally zika virus-exposed infant macaques with dengue immunity","volume":"13","author":"Ausderau","year":"2021","journal-title":"Viruses"},{"key":"B19","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1086\/jid.1999.180.issue-4","article-title":"Measles virus infection in rhesus macaques: altered immune responses and comparison of the virulence of six different virus strains","volume":"180","author":"Auwaerter","year":"1999","journal-title":"J. Infect. Dis."},{"key":"B20","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1590\/S0034-8910.2015049006219","article-title":"Chikungunya risk for Brazil","volume":"49","author":"Azevedo Rdo","year":"2015","journal-title":"Rev. Saude Publica."},{"key":"B21","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1056\/NEJMoa2035389","article-title":"Efficacy and safety of the mRNA-1273 SARS-coV-2 vaccine","volume":"384","author":"Baden","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"B22","doi-asserted-by":"publisher","first-page":"6","DOI":"10.4161\/chim.27778","article-title":"Analysis of maternal microchimerism in rhesus monkeys (Macaca mulatta) using real-time quantitative PCR amplification of MHC polymorphisms","volume":"5","author":"Bakkour","year":"2014","journal-title":"Chimerism."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1542\/peds.107.5.1147","article-title":"An assessment of thimerosal use in childhood vaccines","volume":"107","author":"Ball","year":"2001","journal-title":"Pediatrics."},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines12070810","article-title":"Global update on measles molecular epidemiology","volume":"12","author":"Bankamp","year":"2024","journal-title":"Vaccines (Basel)"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.3390\/v11030294","article-title":"Chikungunya in infants and children: is pathogenesis increasing","volume":"11","author":"Barr","year":"2019","journal-title":"Viruses."},{"key":"B26","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1093\/ilar.47.1.49","article-title":"Nonhuman primate models of intrauterine cytomegalovirus infection","volume":"47","author":"Barry","year":"2006","journal-title":"ILAR J."},{"key":"B27","first-page":"43","article-title":"Development of breeding populations of rhesus macaques (Macaca mulatta) that are specific pathogen-free for rhesus cytomegalovirus","volume":"58","author":"Barry","year":"2008","journal-title":"Comp. Med."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1002\/ar.v297.8","article-title":"Myeloid-lymphoid ontogeny in the rhesus monkey (Macaca mulatta)","volume":"297","author":"Batchelder","year":"2014","journal-title":"Anat Rec (Hoboken)."},{"key":"B29","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/B978-0-12-800964-2.00010-0","article-title":"Chapter 10 - animal models: no model is perfect, but many are useful","volume-title":"Viral pathogenesis","author":"Baxter","year":"2016"},{"key":"B30","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1089\/vim.2021.0171","article-title":"Phenotypic and kinetic changes of myeloid lineage cells in innate response to chikungunya infection in cynomolgus macaques","volume":"35","author":"Beddingfield","year":"2022","journal-title":"Viral Immunol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1128\/iai.9.1.101-105.1974","article-title":"Simian model for the evaluation of immunity to influenza","volume":"9","author":"Berendt","year":"1974","journal-title":"Infect. Immun."},{"key":"B32","doi-asserted-by":"publisher","first-page":"433","DOI":"10.4103\/ijmr.IJMR_169_20","article-title":"Molecular mechanisms of zika virus pathogenesis: An update","volume":"154","author":"Bhagat","year":"2021","journal-title":"Indian J. Med. Res."},{"key":"B33","doi-asserted-by":"publisher","first-page":"2226","DOI":"10.1056\/NEJMra1111853","article-title":"Global maternal, newborn, and child health\u2013so near and yet so far","volume":"369","author":"Bhutta","year":"2013","journal-title":"N Engl. J. Med."},{"key":"B34","doi-asserted-by":"publisher","first-page":"13645","DOI":"10.1073\/pnas.1511526112","article-title":"Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission","volume":"112","author":"Bialas","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"B35","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1084\/jem.33.5.621","article-title":"Studies on measles: iii. Acquired immunity following experimental measles","volume":"33","author":"Blake","year":"1921","journal-title":"J. Exp. Med."},{"key":"B36","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1084\/jem.33.3.413","article-title":"Studies on measles: ii. Symptomatology and pathology in monkeys experimentally infected","volume":"33","author":"Blake","year":"1921","journal-title":"J. Exp. Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1084\/jem.33.3.385","article-title":"Studies on measles: I. Susceptibility of monkeys to the virus of measles","volume":"33","author":"Blake","year":"1921","journal-title":"J. Exp. Med."},{"key":"B38","unstructured":"Board\n              G. P. M.\n            \n          \n          A fragile state of preparedness: 2023 Report on the world\u2019s preparedness\n          \n          2023"},{"key":"B39","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1586\/erv.09.148","article-title":"Animal models for the preclinical evaluation of candidate influenza vaccines","volume":"9","author":"Bodewes","year":"2010","journal-title":"Expert Rev. Vaccines"},{"key":"B40","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1080\/19420862.2016.1274845","article-title":"IgG Fc variant cross-reactivity between human and rhesus macaque FcgammaRs","volume":"9","author":"Boesch","year":"2017","journal-title":"MAbs."},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00589","article-title":"Biophysical and functional characterization of rhesus macaque igG subclasses","volume":"7","author":"Boesch","year":"2016","journal-title":"Front. Immunol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1146\/annurev.ne.08.030185.002431","article-title":"Postnatal development of vision in human and nonhuman primates","volume":"8","author":"Boothe","year":"1985","journal-title":"Annu. Rev. Neurosci."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.3390\/v20801530","article-title":"Animal models for influenza virus pathogenesis and transmission","volume":"2","author":"Bouvier","year":"2010","journal-title":"Viruses."},{"key":"B44","first-page":"242","article-title":"Animal models of zika virus","volume":"67","author":"Bradley","year":"2017","journal-title":"Comp. Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1056\/NEJMoa1602412","article-title":"Zika virus infection in pregnant women in rio de janeiro","volume":"375","author":"Brasil","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"B46","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s11904-021-00584-9","article-title":"Microbiome studies in non-human primates","volume":"18","author":"Brenchley","year":"2021","journal-title":"Curr. HIV\/AIDS Rep."},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1008954","article-title":"Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48\/MVA in combination with TLR-7 stimulation","volume":"16","author":"Bricker","year":"2020","journal-title":"PloS Pathog."},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01699-21","article-title":"Altered response pattern following AZD5582 treatment of SIV-infected, ART-suppressed rhesus macaque infants","volume":"96","author":"Bricker","year":"2022","journal-title":"J. Virol."},{"key":"B49","first-page":"2221","article-title":"Fields virology","volume":"96","author":"Britt","year":"1996","journal-title":"Philadelphia: Lippincott-Raven Publishers."},{"key":"B50","doi-asserted-by":"publisher","first-page":"662","DOI":"10.3390\/pathogens4030662","article-title":"Nonhuman primate models of chikungunya virus infection and disease (CHIKV NHP model)","volume":"4","author":"Broeckel","year":"2015","journal-title":"Pathogens."},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci7040040","article-title":"Hippocampal neuronal loss in infant macaques orally infected with virulent simian immunodeficiency virus (SIV)","volume":"7","author":"Carryl","year":"2017","journal-title":"Brain Sci."},{"key":"B52","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1146\/annurev-immunol-031210-101317","article-title":"Immunoglobulin responses at the mucosal interface","volume":"29","author":"Cerutti","year":"2011","journal-title":"Annu. Rev. Immunol."},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00728-22","article-title":"Pandemic 1918 influenza virus does not cause lethal infection in rhesus or cynomolgus macaques","volume":"96","author":"Chan","year":"2022","journal-title":"J. Virol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/0013-9351(77)90044-5","article-title":"Neurotoxic effects of mercury\u2013a review","volume":"14","author":"Chang","year":"1977","journal-title":"Environ. Res."},{"key":"B55","doi-asserted-by":"publisher","first-page":"9493","DOI":"10.1128\/JVI.76.18.9493-9504.2002","article-title":"A recombinant rhesus cytomegalovirus expressing enhanced green fluorescent protein retains the wild-type phenotype and pathogenicity in fetal macaques","volume":"76","author":"Chang","year":"2002","journal-title":"J. virology."},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.961198","article-title":"Fast-track development of vaccines for SARS-CoV-2: The shots that saved the world","volume":"13","author":"Chavda","year":"2022","journal-title":"Front. Immunol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.4269\/ajtmh.2010.10-0290","article-title":"Comparative pathogenesis of epidemic and enzootic Chikungunya viruses in a pregnant Rhesus macaque model","volume":"83","author":"Chen","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"B58","doi-asserted-by":"publisher","first-page":"15573","DOI":"10.1038\/s41598-018-33950-6","article-title":"Diversity of macaque microbiota compared to the human counterparts","volume":"8","author":"Chen","year":"2018","journal-title":"Sci. Rep."},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10111441","article-title":"Transplacental antibody transfer of respiratory syncytial virus specific igG in non-human primate mother-infant pairs","volume":"10","author":"Citron","year":"2021","journal-title":"Pathogens"},{"key":"B60","doi-asserted-by":"publisher","first-page":"7412","DOI":"10.1128\/JVI.00188-14","article-title":"Enhanced viral replication and modulated innate immune responses in infant airway epithelium following H1N1 infection","volume":"88","author":"Clay","year":"2014","journal-title":"J. Virol."},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.135449","article-title":"Influenza-infected newborn and adult monkeys exhibit a strong primary antibody response to hemagglutinin stem","volume":"5","author":"Clemens","year":"2020","journal-title":"JCI Insight"},{"key":"B62","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1093\/infdis\/jiaa728","article-title":"An R848-conjugated influenza virus vaccine elicits robust immunoglobulin G to hemagglutinin stem in a newborn nonhuman primate model","volume":"224","author":"Clemens","year":"2021","journal-title":"J. Infect. Dis."},{"key":"B63","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1038\/s41541-022-00523-8","article-title":"TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination","volume":"7","author":"Clemens","year":"2022","journal-title":"NPJ Vaccines"},{"key":"B64","doi-asserted-by":"publisher","first-page":"2414","DOI":"10.1038\/s41467-018-04777-6","article-title":"Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease","volume":"9","author":"Coffey","year":"2018","journal-title":"Nat. Commun."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1056\/NEJM199411033311801","article-title":"Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group","volume":"331","author":"Connor","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0040029","article-title":"A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease","volume":"4","author":"Couderc","year":"2008","journal-title":"PloS Pathog."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/j.micinf.2009.09.002","article-title":"Focus on Chikungunya pathophysiology in human and animal models","volume":"11","author":"Couderc","year":"2009","journal-title":"Microbes Infect."},{"key":"B68","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1056\/NEJMoa2203315","article-title":"Evaluation of mRNA-1273 covid-19 vaccine in children 6 to 11 years of age","volume":"386","author":"Creech","year":"2022","journal-title":"N. Engl. J. Med."},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009641","article-title":"Previous exposure to dengue virus is associated with increased Zika virus burden at the maternal-fetal interface in rhesus macaques","volume":"15","author":"Crooks","year":"2021","journal-title":"PloS Negl. Trop. Dis."},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.754710","article-title":"Biophysical evaluation of rhesus macaque fc gamma receptors reveals similar igG fc glycoform preferences to human receptors","volume":"12","author":"Crowley","year":"2021","journal-title":"Front. Immunol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"e00162","DOI":"10.1128\/mSphere.00162-20","article-title":"HIV env-specific igG antibodies induced by vaccination of neonatal rhesus macaques persist and can be augmented by a late booster immunization in infancy","volume":"5","author":"Curtis","year":"2020","journal-title":"mSphere."},{"key":"B72","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1289\/ehp.1408257","article-title":"Examination of the safety of pediatric vaccine schedules in a non-human primate model: assessments of neurodevelopment, learning, and social behavior","volume":"123","author":"Curtis","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"B73","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1097\/WNR.0000000000000148","article-title":"Reduction of pyramidal and immature hippocampal neurons in pediatric simian immunodeficiency virus infection","volume":"25","author":"Curtis","year":"2014","journal-title":"Neuroreport."},{"key":"B74","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/s41579-022-00846-2","article-title":"Long COVID: major findings, mechanisms and recommendations","volume":"21","author":"Davis","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"key":"B75","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1600-0684.1990.tb00443.x","article-title":"Experimental infection of timed-pregnant rhesus monkeys with simian immunodeficiency virus (SIV) during early, middle, and late gestation","volume":"19","author":"Davison-Fairburn","year":"1990","journal-title":"J. Med. Primatol"},{"key":"B76","doi-asserted-by":"publisher","first-page":"13036","DOI":"10.1073\/pnas.1903317116","article-title":"Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity","volume":"116","author":"Deere","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"B77","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/j.1600-0684.2012.00541.x","article-title":"Use of specific-pathogen-free (SPF) rhesus macaques to better model oral pediatric cytomegalovirus infection","volume":"41","author":"dela Pena","year":"2012","journal-title":"J. Med. Primatol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1097\/COH.0000000000000311","article-title":"Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies: model parameter considerations and consequences","volume":"11","author":"Del Prete","year":"2016","journal-title":"Curr. Opin. HIV AIDS."},{"key":"B79","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1034\/j.1600-0609.2000.065004245.x","article-title":"Characterization of lymphocyte subsets in rhesus macaques during the first year of life","volume":"65","author":"DeMaria","year":"2000","journal-title":"Eur. J. Haematol."},{"key":"B80","doi-asserted-by":"publisher","first-page":"S39","DOI":"10.1038\/sj.embor.7400422","article-title":"Of mice and men. When it comes to studying ageing and the means to slow it down, mice are not just small humans","author":"Demetrius","year":"2005","journal-title":"EMBO Rep."},{"key":"B81","doi-asserted-by":"publisher","first-page":"e01783","DOI":"10.1128\/JVI.01783-18","article-title":"Co-administration of CH31 broadly neutralizing antibody does not affect development of vaccine-induced anti-HIV-1 envelope antibody responses in infant Rhesus macaques","volume":"93","author":"Dennis","year":"2019","journal-title":"J. Virol."},{"key":"B82","volume-title":"Figure\u00a01: age comparison between humans and rhesus macaques","author":"De Paris","year":"2024"},{"key":"B83","volume-title":"Figure\u00a02: pediatric infection models of viral diseases in NHP","author":"De Paris","year":"2024"},{"key":"B84","volume-title":"Figure\u00a03: challenges of mouse models for pediatric viral diseases","author":"De Paris","year":"2024"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1142636","article-title":"Editorial: Congenital and perinatal infections: How to prevent sequelaes in neonates and children","volume":"11","author":"De Rose","year":"2023","journal-title":"Front. Pediatr."},{"key":"B86","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.chom.2024.02.011","article-title":"Pathophysiology of chikungunya virus infection associated with fatal outcomes","volume":"32","author":"de Souza","year":"2024","journal-title":"Cell Host Microbe"},{"key":"B87","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1128\/JVI.01783-18","article-title":"Measles studies in the macaque model","volume":"330","author":"de Swart","year":"2009","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030178","article-title":"Predominant infection of CD150+ lymphocytes and dendritic cells during measles virus infection of macaques","volume":"3","author":"de Swart","year":"2007","journal-title":"PloS Pathog."},{"key":"B89","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1038\/s41586-020-2708-8","article-title":"A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures","volume":"586","author":"Dinnon","year":"2020","journal-title":"Nature."},{"key":"B90","doi-asserted-by":"publisher","first-page":"110772","DOI":"10.1016\/j.celrep.2022.110772","article-title":"Bacille Calmette-Guerin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro","volume":"39","author":"Diray-Arce","year":"2022","journal-title":"Cell Rep."},{"key":"B91","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.3892\/ijmm.2020.4555","article-title":"A new threat from an old enemy: Re\u2212emergence of coronavirus (Review)","volume":"45","author":"Docea","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9102110","article-title":"Nurturing the early life gut microbiome and immune maturation for long term health","volume":"9","author":"Dogra","year":"2021","journal-title":"Microorganisms."},{"key":"B93","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1126\/science.aai9137","article-title":"Rapid development of a DNA vaccine for Zika virus","volume":"354","author":"Dowd","year":"2016","journal-title":"Science."},{"key":"B94","doi-asserted-by":"publisher","first-page":"12204","DOI":"10.1038\/ncomms12204","article-title":"A rhesus macaque model of Asian-lineage Zika virus infection","volume":"7","author":"Dudley","year":"2016","journal-title":"Nat. Commun."},{"key":"B95","volume-title":"Chikungunya worldwide overview Stockholm","year":"2024"},{"key":"B96","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1017\/S0950268808001167","article-title":"Atypical Chikungunya virus infections: clinical manifestations, mortality and risk factors for severe disease during the 2005-2006 outbreak on Reunion","volume":"137","author":"Economopoulou","year":"2009","journal-title":"Epidemiol. Infect."},{"key":"B97","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1056\/NEJMoa2113017","article-title":"Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase","volume":"385","author":"El Sahly","year":"2021","journal-title":"N Engl. J. Med."},{"key":"B98","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1056\/NEJM196007282630401","article-title":"Studies on an attenuated measles-virus vaccine. I. Development and preparations of the vaccine: technics for assay of effects of vaccination","volume":"263","author":"Enders","year":"1960","journal-title":"N Engl. J. Med."},{"key":"B99","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1038\/s41577-018-0005-7","article-title":"Nonhuman primate models of human viral infections","volume":"18","author":"Estes","year":"2018","journal-title":"Nat. Rev. Immunol."},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01094-23","article-title":"Host immunity associated with spontaneous suppression of viremia in therapy-naive young rhesus macaques following neonatal SHIV infection","volume":"97","author":"Evangelous","year":"2023","journal-title":"J. Virol."},{"key":"B101","doi-asserted-by":"publisher","first-page":"103747","DOI":"10.1016\/j.bjid.2024.103747","article-title":"Vertical transmission of chikungunya virus: a worldwide concern","volume":"28","author":"Faria","year":"2024","journal-title":"Braz. J. Infect. Dis."},{"key":"B102","first-page":"107","article-title":"Simian immunodeficiency virus infection via amniotic fluid: a model to study fetal immunopathogenesis and prophylaxis","volume":"6","author":"Fazely","year":"1993","journal-title":"J. Acquir. Immune Defic. Syndr. (1988)."},{"key":"B103","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1086\/jid.2004.189.issue-12","article-title":"Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies","volume":"189","author":"Ferrantelli","year":"2004","journal-title":"J. Infect. Dis."},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272761","article-title":"Correction: Vertical transmission of chikungunya virus: A systematic review","volume":"17","author":"Ferreira","year":"2022","journal-title":"PloS One"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22010214","article-title":"A review of murine cytomegalovirus as a model for human cytomegalovirus disease-do mice lie","volume":"22","author":"Fisher","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"B106","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4049\/immunohorizons.1700057","article-title":"The Impact of IgG transplacental transfer on early life immunity","volume":"2","author":"Fouda","year":"2018","journal-title":"Immunohorizons."},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.855230","article-title":"A case study to dissect immunity to SARS-coV-2 in a neonate nonhuman primate model","volume":"13","author":"Fovet","year":"2022","journal-title":"Front. Immunol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1001\/jama.289.8.1008","article-title":"Maternal immunity and prevention of congenital cytomegalovirus infection","volume":"289","author":"Fowler","year":"2003","journal-title":"Jama."},{"key":"B109","doi-asserted-by":"publisher","first-page":"378","DOI":"10.2500\/aap.2021.42.210065","article-title":"The global burden of vaccine-preventable infectious diseases in children less than 5 years of age: Implications for COVID-19 vaccination","volume":"42","author":"Frenkel","year":"2021","journal-title":"How Can. we do better? Allergy Asthma Proc."},{"key":"B110","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1159\/000150124","article-title":"HIV infection of chimpanzees as a model for testing chemotherapeutics","author":"Fultz","year":"1989","journal-title":"Intervirology."},{"key":"B111","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1293\/tox.2013-0060","article-title":"A comparison of the histological structure of the placenta in experimental animals","volume":"27","author":"Furukawa","year":"2014","journal-title":"J. Toxicol. Pathol."},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.3390\/v9120368","article-title":"Chikungunya virus: pathophysiology, mechanism, and modeling","volume":"9","author":"Ganesan","year":"2017","journal-title":"Viruses."},{"key":"B113","doi-asserted-by":"publisher","first-page":"8021","DOI":"10.1128\/JVI.02603-09","article-title":"Chikungunya virus arthritis in adult wild-type mice","volume":"84","author":"Gardner","year":"2010","journal-title":"J. Virol."},{"key":"B114","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.virol.2011.12.020","article-title":"Interferon-alpha\/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181\/25 vaccine candidate","volume":"425","author":"Gardner","year":"2012","journal-title":"Virology."},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abj3684","article-title":"SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques","volume":"6","author":"Garrido","year":"2021","journal-title":"Sci. Immunol."},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1107496","article-title":"Structural and immunological basis of cross-reactivity between dengue and Zika infections: Implications in serosurveillance in endemic regions","volume":"14","author":"Gaspar-Castillo","year":"2023","journal-title":"Front. Microbiol."},{"key":"B117","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/S0140-6736(17)33105-7","article-title":"Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials","volume":"391","author":"Gaudinski","year":"2018","journal-title":"Lancet."},{"key":"B118","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1126\/science.aad9378","article-title":"How colonization by microbiota in early life shapes the immune system","volume":"352","author":"Gensollen","year":"2016","journal-title":"Science."},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050060","article-title":"Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Reunion","volume":"5","author":"Gerardin","year":"2008","journal-title":"PloS Med."},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002996","article-title":"Neurocognitive outcome of children exposed to perinatal mother-to-child Chikungunya virus infection: the CHIMERE cohort study on Reunion Island","volume":"8","author":"Gerardin","year":"2014","journal-title":"PloS Negl. Trop. Dis."},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1101\/2021.08.09.21261290","article-title":"Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy trial","author":"Gilbert","year":"2021","journal-title":"medRxiv."},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.617516","article-title":"Advances in humanized mouse models to improve understanding of HIV-1 pathogenesis and immune responses","volume":"11","author":"Gillgrass","year":"2020","journal-title":"Front. Immunol."},{"key":"B123","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1477-7827-2-35","article-title":"Pregnancy initiation in the rhesus macaque: towards functional manipulation of the maternal-fetal interface","volume":"2","author":"Golos","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"key":"B124","doi-asserted-by":"publisher","first-page":"19","DOI":"10.4161\/self.2.1.15094","article-title":"Conceptual aspects of self and nonself discrimination","volume":"2","author":"Gonzalez","year":"2011","journal-title":"Self Nonself."},{"key":"B125","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1089\/vim.2017.0143","article-title":"Measles vaccine","volume":"31","author":"Griffin","year":"2018","journal-title":"Viral Immunol."},{"key":"B126","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.2741\/2767","article-title":"Measles vaccines","volume":"13","author":"Griffin","year":"2008","journal-title":"Front. Biosci."},{"key":"B127","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/s41579-021-00582-z","article-title":"Pathogenesis of human cytomegalovirus in the immunocompromised host","volume":"19","author":"Griffiths","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00126","article-title":"Mouse models of influenza infection with circulating strains to test seasonal vaccine efficacy","volume":"9","author":"Groves","year":"2018","journal-title":"Front. Immunol."},{"key":"B129","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1038\/mi.2013.64","article-title":"Limited expression of APRIL and its receptors prior to intestinal IgA plasma cell development during human infancy","volume":"7","author":"Gustafson","year":"2014","journal-title":"Mucosal Immunol."},{"key":"B130","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1007\/s13365-021-01019-2","article-title":"Reduced neuronal population in the dorsolateral prefrontal cortex in infant macaques infected with simian immunodeficiency virus (SIV)","volume":"27","author":"Haddad","year":"2021","journal-title":"J. Neurovirol."},{"key":"B131","doi-asserted-by":"publisher","first-page":"S482","DOI":"10.1093\/infdis\/jiw284","article-title":"Animal models of chikungunya virus infection and disease","volume":"214","author":"Haese","year":"2016","journal-title":"J. Infect. Dis."},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.3390\/v13102088","article-title":"Nonhuman primate models of zika virus infection and disease during pregnancy","volume":"13","author":"Haese","year":"2021","journal-title":"Viruses."},{"key":"B133","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1086\/587643","article-title":"Safety and immunogenicity of trivalent inactivated influenza vaccine in infants","volume":"197","author":"Halasa","year":"2008","journal-title":"J. Infect. Dis."},{"key":"B134","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1177\/030098587100800403","article-title":"Pathology of measles in rhesus monkeys","volume":"8","author":"Hall","year":"1971","journal-title":"Vet. Pathol."},{"key":"B135","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1084\/jem.20071068","article-title":"Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression","volume":"204","author":"Hartigan-O\u2019Connor","year":"2007","journal-title":"J. Exp. Med."},{"key":"B136","doi-asserted-by":"publisher","first-page":"13878","DOI":"10.1128\/JVI.02666-13","article-title":"Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response","volume":"87","author":"Hawman","year":"2013","journal-title":"J. Virol."},{"key":"B137","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1097\/COH.0000000000000820","article-title":"Progress with induction of HIV broadly neutralizing antibodies in the Duke Consortia for HIV\/AIDS Vaccine Development","volume":"18","author":"Haynes","year":"2023","journal-title":"Curr. Opin. HIV AIDS."},{"key":"B138","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1191\/096032700678815756","article-title":"Nonhuman primates: their role in assessing developmental effects of immunomodulatory agents","volume":"19","author":"Hendrickx","year":"2000","journal-title":"Hum. Exp. Toxicol."},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1340017","article-title":"Marmosets as models of infectious diseases","volume":"14","author":"Herron","year":"2024","journal-title":"Front. Cell Infect. Microbiol."},{"key":"B140","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1038\/nm.4063","article-title":"Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques","volume":"22","author":"Hessell","year":"2016","journal-title":"Nat. Med."},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.194.Supp.212.10","article-title":"Post-exposure treatment with neutralizing monoclonal antibodies prevents SHIV infection in infant rhesus macaques and limits establishment of latent viral reservoirs (VAC11P.1102)","volume":"194","author":"Hessell","year":"2015","journal-title":"J. Immunol."},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02198-17","article-title":"Reduced cell-associated DNA and improved viral control in macaques following passive transfer of a single anti-V2 monoclonal antibody and repeated simian\/human immunodeficiency virus challenges","volume":"92","author":"Hessell","year":"2018","journal-title":"J. Virol."},{"key":"B143","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.coviro.2018.01.006","article-title":"The immune response to CMV infection and vaccination in mice, monkeys and humans: recent developments","volume":"28","author":"Hill","year":"2018","journal-title":"Curr. Opin. Virology."},{"key":"B144","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/s41467-017-02499-9","article-title":"Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology","volume":"9","author":"Hirsch","year":"2018","journal-title":"Nat. Commun."},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines12040415","article-title":"Sex-dependent effects on influenza-specific antibody quantity and neutralizing activity following vaccination of newborn non-human primates is determined by adjuvants","volume":"12","author":"Holbrook","year":"2024","journal-title":"Vaccines (Basel)."},{"key":"B146","doi-asserted-by":"publisher","first-page":"4712","DOI":"10.1016\/j.vaccine.2016.08.010","article-title":"Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model","volume":"34","author":"Holbrook","year":"2016","journal-title":"Vaccine."},{"key":"B147","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.virol.2014.12.007","article-title":"Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection","volume":"476","author":"Holbrook","year":"2015","journal-title":"Virology."},{"key":"B148","doi-asserted-by":"publisher","first-page":"112255","DOI":"10.1016\/j.celrep.2023.112255","article-title":"Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies","volume":"42","author":"Hora","year":"2023","journal-title":"Cell Rep."},{"key":"B149","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.bioactmat.2022.09.010","article-title":"3D engineered tissue models for studying human-specific infectious viral diseases","volume":"21","author":"Hwang","year":"2023","journal-title":"Bioact Mater."},{"key":"B150","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.coviro.2017.08.005","article-title":"Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections","volume":"25","author":"Itell","year":"2017","journal-title":"Curr. Opin. Virology."},{"key":"B151","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.coviro.2017.08.005","article-title":"Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections","volume":"25","author":"Itell","year":"2017","journal-title":"Curr. Opin. Virol."},{"key":"B152","doi-asserted-by":"publisher","first-page":"S73","DOI":"10.1016\/j.placenta.2017.04.011","article-title":"Maternal immune correlates of protection against placental transmission of cytomegalovirus","author":"Itell","year":"2017","journal-title":"Placenta."},{"key":"B153","doi-asserted-by":"publisher","first-page":"1824564","DOI":"10.1080\/19490976.2020.1824564","article-title":"The early life education of the immune system: Moms, microbes and (missed) opportunities","volume":"12","author":"Jain","year":"2020","journal-title":"Gut Microbes"},{"key":"B154","doi-asserted-by":"publisher","first-page":"10447","DOI":"10.1128\/JVI.00049-13","article-title":"Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques","volume":"87","author":"Jaworski","year":"2013","journal-title":"J. Virol."},{"key":"B155","doi-asserted-by":"publisher","first-page":"2828","DOI":"10.2741\/2012","article-title":"Animal models for perinatal transmission of HIV-1","volume":"11","author":"Jayaraman","year":"2006","journal-title":"Front. Biosci."},{"key":"B156","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1111\/j.1600-0684.2004.00079.x","article-title":"Perinatal transmission of SHIV-SF162P3 in Macaca nemestrina","volume":"33","author":"Jayaraman","year":"2004","journal-title":"J. Med. Primatol."},{"key":"B157","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00360-16","article-title":"Balancing trained immunity with persistent immune activation and the risk of SIV infection in infant macaques vaccinated with attenuated Mycobacterium tuberculosis or BCG vaccines","author":"Jensen","year":"2016","journal-title":"Clin. Vaccine Immunol"},{"key":"B158","doi-asserted-by":"publisher","first-page":"7285","DOI":"10.1128\/JVI.00481-16","article-title":"Vaccine-elicited mucosal and systemic antibody responses are associated with reduced simian immunodeficiency viremia in infant rhesus macaques","volume":"90","author":"Jensen","year":"2016","journal-title":"J. Virol."},{"key":"B159","doi-asserted-by":"publisher","first-page":"11115","DOI":"10.1128\/JVI.01571-12","article-title":"Increased viral loads and exacerbated innate host responses in aged macaques infected with the 2009 pandemic H1N1 influenza A virus","volume":"86","author":"Josset","year":"2012","journal-title":"J. Virol."},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095647","article-title":"Unique epitopes recognized by antibodies induced in Chikungunya virus-infected non-human primates: implications for the study of immunopathology and vaccine development","volume":"9","author":"Kam","year":"2014","journal-title":"PloS One"},{"key":"B161","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.3201\/eid1810.120214","article-title":"Influenza virus infection in nonhuman primates","volume":"18","author":"Karlsson","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"B162","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1056\/NEJM196007282630408","article-title":"Studies on an attenuated measles-virus vaccine. VIII. General summary and evaluation of the results of vaccine","volume":"263","author":"Katz","year":"1960","journal-title":"N Engl. J. Med."},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0206330","article-title":"Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys","volume":"13","author":"Kaur","year":"2018","journal-title":"PloS One"},{"key":"B164","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2023-063678N","article-title":"Child health needs and the pediatric infectious diseases workforce: 2020-2040","volume":"153","author":"Kelly","year":"2024","journal-title":"Pediatrics."},{"key":"B165","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1093\/geroni\/igz038.3472","article-title":"Database for indices of aging in nonhuman primates","volume":"3","author":"Kemnitz","year":"2019","journal-title":"Innov. Aging"},{"key":"B166","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/BF01253798","article-title":"The pathogenesis of measles virus infection","volume":"16","author":"Kempe","year":"1965","journal-title":"Arch. Gesamte Virusforsch."},{"key":"B167","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/rmv.v17:4","article-title":"Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection","volume":"17","author":"Kenneson","year":"2007","journal-title":"Rev. Med. Virol."},{"key":"B168","doi-asserted-by":"publisher","DOI":"10.3389\/fviro.2023.1106634","article-title":"Modeling of vertical transmission and pathogenesis of cytomegalovirus in pregnancy: Opportunities and challenges","volume":"3","author":"Kirschen","year":"2023","journal-title":"Front. Virol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"383","DOI":"10.30802\/AALAS-CM-21-000031","article-title":"Mouse models for the study of SARS-coV-2 infection","volume":"71","author":"Knight","year":"2021","journal-title":"Comp. Med."},{"key":"B170","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1038\/nature05495","article-title":"Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus","volume":"445","author":"Kobasa","year":"2007","journal-title":"Nature."},{"key":"B171","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1099\/0022-1317-78-8-2009","article-title":"Cloning and characterization of rhesus cytomegalovirus glycoprotein B","volume":"78","author":"Kravitz","year":"1997","journal-title":"J. Gen. Virol."},{"key":"B172","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1126\/science.abn7829","article-title":"A global catalog of whole-genome diversity from 233 primate species","volume":"380","author":"Kuderna","year":"2023","journal-title":"Science."},{"key":"B173","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0140-6736(03)13967-0","article-title":"Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome","volume":"362","author":"Kuiken","year":"2003","journal-title":"Lancet."},{"key":"B174","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1354\/vp.40-3-304","article-title":"Pathology of human influenza A (H5N1) virus infection in cynomolgus macaques (Macaca fascicularis)","volume":"40","author":"Kuiken","year":"2003","journal-title":"Vet. Pathol."},{"key":"B175","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1172\/JCI40104","article-title":"Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages","volume":"120","author":"Labadie","year":"2010","journal-title":"J. Clin. Invest."},{"key":"B176","doi-asserted-by":"publisher","DOI":"10.3390\/v13081582","article-title":"Comparable infection level and tropism of measles virus and canine distemper virus in organotypic brain slice cultures obtained from natural host species","volume":"13","author":"Laksono","year":"2021","journal-title":"Viruses"},{"key":"B177","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/ilar.42.2.117","article-title":"The chimpanzee model of hepatitis C virus infections","volume":"42","author":"Lanford","year":"2001","journal-title":"ILAR J."},{"key":"B178","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.chom.2022.04.007","article-title":"Maternal immune protection against infectious diseases","volume":"30","author":"Langel","year":"2022","journal-title":"Cell Host Microbe"},{"key":"B179","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1007\/s12325-023-02432-1","article-title":"High clinical burden of influenza disease in adults aged >\/= 65 years: can we do better? A systematic literature review","volume":"40","author":"Langer","year":"2023","journal-title":"Adv. Ther."},{"key":"B180","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.ijid.2013.12.010","article-title":"Systematic review of the birth prevalence of congenital cytomegalovirus infection in developing countries","volume":"22","author":"Lanzieri","year":"2014","journal-title":"Int. J. Infect. Dis."},{"key":"B181","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.chom.2016.03.010","article-title":"A mouse model of zika virus pathogenesis","volume":"19","author":"Lazear","year":"2016","journal-title":"Cell Host Microbe"},{"key":"B182","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1038\/s41467-019-08794-x","article-title":"Dynamic molecular changes during the first week of human life follow a robust developmental trajectory","volume":"10","author":"Lee","year":"2019","journal-title":"Nat. Commun."},{"key":"B183","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.molimm.2021.04.010","article-title":"Non-human primate models of human respiratory infections","volume":"135","author":"Lemaitre","year":"2021","journal-title":"Mol. Immunol."},{"key":"B184","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1093\/infdis\/jiac129","article-title":"Horizontal transmission of cytomegalovirus in a rhesus model despite high-level, vaccine-elicited neutralizing antibody and T-cell responses","volume":"226","author":"Li","year":"2022","journal-title":"J. Infect. Dis."},{"key":"B185","doi-asserted-by":"publisher","first-page":"19950","DOI":"10.1073\/pnas.0811063106","article-title":"Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types","volume":"105","author":"Lilja","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"B186","doi-asserted-by":"publisher","first-page":"9576","DOI":"10.1128\/JVI.73.11.9576-9583.1999","article-title":"Pathogenesis of experimental rhesus cytomegalovirus infection","volume":"73","author":"Lockridge","year":"1999","journal-title":"J. Virol."},{"key":"B187","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1093\/pch\/14.9.612","article-title":"Protecting young babies from influenza","volume":"14","author":"Macdonald","year":"2009","journal-title":"Paediatr. Child Health"},{"key":"B188","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1128\/CDLI.10.1.140-153.2003","article-title":"Functional and morphological development of lymphoid tissues and immune regulatory and effector function in rhesus monkeys: cytokine-secreting cells, immunoglobulin-secreting cells, and CD5(+) B-1 cells appear early in fetal development","volume":"10","author":"Makori","year":"2003","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"B189","doi-asserted-by":"publisher","DOI":"10.3390\/children9020249","article-title":"COVID-19 infection in children and infants: current status on therapies and vaccines","volume":"9","author":"Malcangi","year":"2022","journal-title":"Children (Basel)"},{"key":"B190","first-page":"71","article-title":"Response of ferrets and monkeys to intranasal infection with human, equine and avian influenza viruses","volume":"35","author":"Marois","year":"1971","journal-title":"Can. J. Comp. Med."},{"key":"B191","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1097\/COH.0b013e3282cecf21","article-title":"Developing a neonatal HIV vaccine: insights from macaque models of pediatric HIV\/AIDS","volume":"2","author":"Marthas","year":"2007","journal-title":"Curr. Opin. HIV AIDS."},{"key":"B192","doi-asserted-by":"publisher","first-page":"3124","DOI":"10.1016\/j.vaccine.2011.02.051","article-title":"Partial efficacy of a VSV-SIV\/MVA-SIV vaccine regimen against oral SIV challenge in infant macaques","volume":"29","author":"Marthas","year":"2011","journal-title":"Vaccine."},{"key":"B193","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1016\/j.cell.2018.03.019","article-title":"Fetal neuropathology in zika virus-infected pregnant female rhesus monkeys","volume":"173","author":"Martinot","year":"2018","journal-title":"Cell."},{"key":"B194","doi-asserted-by":"publisher","first-page":"412","DOI":"10.3201\/eid1403.070720","article-title":"Increased mortality rate associated with chikungunya epidemic, Ahmedabad, India","volume":"14","author":"Mavalankar","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"B195","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00562-18","article-title":"Simian immunodeficiency virus persistence in cellular and anatomic reservoirs in antiretroviral therapy-suppressed infant rhesus macaques","volume":"92","author":"Mavigner","year":"2018","journal-title":"J. Virol."},{"key":"B196","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1006\/viro.1997.8576","article-title":"Experimental measles. I. Pathogenesis in the normal and the immunized host","volume":"233","author":"McChesney","year":"1997","journal-title":"Virology."},{"key":"B197","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/j.1600-0684.1991.tb00516.x","article-title":"Maternal transmission of SIVsmm in rhesus macaques","volume":"20","author":"McClure","year":"1991","journal-title":"J. Med. Primatol."},{"key":"B198","doi-asserted-by":"publisher","first-page":"1916","DOI":"10.1093\/infdis\/jiab229","article-title":"Safety, tolerability, and pharmacokinetics of a long-acting broadly neutralizing human immunodeficiency virus type 1 (HIV-1) monoclonal antibody VRC01LS in HIV-1-exposed newborn infants","volume":"224","author":"McFarland","year":"2021","journal-title":"J. Infect. Dis."},{"key":"B199","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1038\/s41586-020-03041-6","article-title":"Correlates of protection against SARS-CoV-2 in rhesus macaques","volume":"590","author":"McMahan","year":"2021","journal-title":"Nature."},{"key":"B200","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taad156","article-title":"A randomized, double-blinded Phase 3 study to demonstrate lot-to-lot consistency and to confirm immunogenicity and safety of the live-attenuated chikungunya virus vaccine candidate VLA1553 in healthy adultsdagger","volume":"31","author":"McMahon","year":"2024","journal-title":"J. Travel Med."},{"key":"B201","doi-asserted-by":"publisher","first-page":"578148","DOI":"10.1016\/j.jneuroim.2023.578148","article-title":"Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques","volume":"381","author":"Medina","year":"2023","journal-title":"J. Neuroimmunol."},{"key":"B202","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/s41579-021-00610-y","article-title":"Infections at the maternal-fetal interface: an overview of pathogenesis and defence","volume":"20","author":"Megli","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"B203","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002343","article-title":"Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity","volume":"7","author":"Messaoudi","year":"2013","journal-title":"PloS Negl. Trop. Dis."},{"key":"B204","doi-asserted-by":"publisher","first-page":"2731","DOI":"10.4049\/jimmunol.172.5.2731","article-title":"Of mice and not men: differences between mouse and human immunology","volume":"172","author":"Mestas","year":"2004","journal-title":"J. Immunol."},{"key":"B205","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1093\/ilar\/ilx030","article-title":"Nonhuman primate models of respiratory disease: past, present, and future","volume":"58","author":"Miller","year":"2017","journal-title":"ILAR J."},{"key":"B206","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.add6383","article-title":"Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later","volume":"15","author":"Milligan","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"B207","doi-asserted-by":"publisher","first-page":"3208","DOI":"10.1016\/j.celrep.2016.08.079","article-title":"Zika virus infection in mice causes panuveitis with shedding of virus in tears","volume":"16","author":"Miner","year":"2016","journal-title":"Cell Rep."},{"key":"B208","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.15585\/mmwr.mm7246a3","article-title":"Progress toward measles elimination - worldwide, 2000-2022","volume":"72","author":"Minta","year":"2023","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"B209","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1093\/jpids\/piy120","article-title":"Modeling zika virus-associated birth defects in nonhuman primates","volume":"7","author":"Mohr","year":"2018","journal-title":"J. Pediatr. Infect. Dis. Soc."},{"key":"B210","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1016\/S0140-6736(05)61664-9","article-title":"Measles vaccine and neurological events","volume":"1997","author":"Montgomery","year":"1997","journal-title":"Lancet"},{"key":"B211","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00009-17","article-title":"Animal models of zika virus infection, pathogenesis, and immunity","volume":"91","author":"Morrison","year":"2017","journal-title":"J. Virol."},{"key":"B212","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.ajpath.2010.11.018","article-title":"A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence","volume":"178","author":"Morrison","year":"2011","journal-title":"Am. J. Pathol."},{"key":"B213","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.it.2023.11.002","article-title":"Modeling human immune responses to vaccination in vitro","volume":"45","author":"Morrocchi","year":"2024","journal-title":"Trends Immunol."},{"key":"B214","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1056\/NEJMra050700","article-title":"Newborn hearing screening\u2013a silent revolution","volume":"354","author":"Morton","year":"2006","journal-title":"N Engl. J. Med."},{"key":"B215","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0140-6736(10)62352-5","article-title":"Measles","volume":"379","author":"Moss","year":"2012","journal-title":"Lancet"},{"key":"B216","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1011646","article-title":"Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection","volume":"19","author":"Mostrom","year":"2023","journal-title":"PloS Pathog."},{"key":"B217","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1056\/NEJMoa2211031","article-title":"Evaluation of BNT162b2 covid-19 vaccine in children younger than 5 years of age","volume":"388","author":"Munoz","year":"2023","journal-title":"N Engl. J. Med."},{"key":"B218","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1038\/s41586-020-2324-7","article-title":"Respiratory disease in rhesus macaques inoculated with SARS-CoV-2","volume":"585","author":"Munster","year":"2020","journal-title":"Nature."},{"key":"B219","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1038\/s41598-020-57471-3","article-title":"Differential expression of PDGF receptor-alpha in human placental trophoblasts leads to different entry pathways by human cytomegalovirus strains","volume":"10","author":"Naing","year":"2020","journal-title":"Sci. Rep."},{"key":"B220","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1086\/522519","article-title":"Age-dependent differences in IgG isotype and avidity induced by measles vaccine received during the first year of life","volume":"196","author":"Nair","year":"2007","journal-title":"J. Infect. Dis."},{"key":"B221","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1080\/19490976.2015.1067743","article-title":"Persistent effects of early infant diet and associated microbiota on the juvenile immune system","volume":"6","author":"Narayan","year":"2015","journal-title":"Gut Microbes"},{"key":"B222","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/S0966-842X(00)01816-3","article-title":"The chimpanzee and other non-human-primate models in HIV-1 vaccine research","volume":"8","author":"Nath","year":"2000","journal-title":"Trends Microbiol."},{"key":"B223","volume-title":"Nonhuman primate models in biomedical research: State of science and future needs","year":"2023"},{"key":"B224","unstructured":"The macaque website United Kingdom: national centre for the replacement, refinement and reduction of animals in research\n          \n          2023"},{"key":"B225","article-title":"Guide for the care and use of laboratory animals","year":"2011"},{"key":"B226","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1002\/dev.21940","article-title":"The quality of early infant-caregiver relational attachment and longitudinal changes in infant inflammation across 6 months","volume":"62","author":"Nelson","year":"2020","journal-title":"Dev. Psychobiol."},{"key":"B227","doi-asserted-by":"publisher","first-page":"eadm7097","DOI":"10.1126\/sciimmunol.adm7097","article-title":"Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques","volume":"9","author":"Nelson","year":"2024","journal-title":"Sci. Immunol."},{"key":"B228","doi-asserted-by":"publisher","DOI":"10.3390\/v13061011","article-title":"Animal models for influenza research: strengths and weaknesses","volume":"13","author":"Nguyen","year":"2021","journal-title":"Viruses."},{"key":"B229","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s00251-011-0514-z","article-title":"Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes","volume":"63","author":"Nguyen","year":"2011","journal-title":"Immunogenetics."},{"key":"B230","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9060584","article-title":"Neonatal immune system ontogeny: the role of maternal microbiota and associated factors. How might the non-human primate model enlighten the path","volume":"9","author":"Nunez","year":"2021","journal-title":"Vaccines (Basel)."},{"key":"B231","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1016\/j.micinf.2011.01.014","article-title":"The contribution of animal models to the understanding of the host range and virulence of influenza A viruses","volume":"13","author":"O\u2019Donnell","year":"2011","journal-title":"Microbes Infect."},{"key":"B232","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-020-00503-4","article-title":"Simian-human immunodeficiency virus SHIV.C.CH505 persistence in ART-suppressed infant macaques is characterized by elevated SHIV RNA in the gut and a high abundance of intact SHIV DNA in naive CD4(+) T cells","volume":"95","author":"Obregon-Perko","year":"2020","journal-title":"J. Virol."},{"key":"B233","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1111\/j.1600-0684.1993.tb00655.x","article-title":"Intra-amniotic inoculation of pigtailed macaque (Macaca nemestrina) fetuses with SIV and HIV-1","volume":"22","author":"Ochs","year":"1993","journal-title":"J. Med. Primatol."},{"key":"B234","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1128\/JVI.02134-06","article-title":"Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection","volume":"81","author":"Ohno","year":"2007","journal-title":"J. Virol."},{"key":"B235","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1016\/j.cell.2018.06.045","article-title":"Stereotypic immune system development in newborn children","volume":"174","author":"Olin","year":"2018","journal-title":"Cell."},{"key":"B236","volume-title":"Global vector control response 2017-2030","author":"Organization","year":"2017"},{"key":"B237","volume-title":"HIV and AIDS. Factsheet","year":"2024"},{"key":"B238","doi-asserted-by":"publisher","first-page":"S42","DOI":"10.1093\/infdis\/170.Supplement_1.S42","article-title":"Measles vaccines: novel generations and new strategies","author":"Osterhaus","year":"1994","journal-title":"J. Infect. Dis."},{"key":"B239","doi-asserted-by":"publisher","first-page":"e1011378","DOI":"10.1371\/journal.ppat.1011378","article-title":"Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model","volume":"19","author":"Otero","year":"2023","journal-title":"PloS Pathog."},{"key":"B240","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12979-015-0030-3","article-title":"The interplay between immune maturation, age, chronic viral infection and environment","volume":"12","author":"Oxford","year":"2015","journal-title":"Immun. Ageing."},{"key":"B241","doi-asserted-by":"publisher","first-page":"5105","DOI":"10.1128\/JVI.02631-10","article-title":"Open reading frames carried on UL\/b\u2019 are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys","volume":"85","author":"Oxford","year":"2011","journal-title":"J. Virol."},{"key":"B242","doi-asserted-by":"publisher","first-page":"8213","DOI":"10.1128\/JVI.01032-14","article-title":"Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes","volume":"88","author":"Pal","year":"2014","journal-title":"J. Virol."},{"key":"B243","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1038\/nature21428","article-title":"Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination","volume":"543","author":"Pardi","year":"2017","journal-title":"Nature."},{"key":"B244","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/bdrb.20201","article-title":"An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies","volume":"86","author":"Pentsuk","year":"2009","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"key":"B245","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/S2352-4642(21)00311-4","article-title":"Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals","volume":"6","author":"Perin","year":"2022","journal-title":"Lancet Child Adolesc. Health"},{"key":"B246","doi-asserted-by":"publisher","first-page":"e00231","DOI":"10.1128\/CVI.00231-17","article-title":"Impact of poxvirus vector priming, protein coadministration, and vaccine intervals on HIV gp120 vaccine-elicited antibody magnitude and function in infant macaques","volume":"24","author":"Phillips","year":"2017","journal-title":"Clin. Vaccine Immunol."},{"key":"B247","doi-asserted-by":"publisher","first-page":"e01051","DOI":"10.1128\/JVI.01051-18","article-title":"Adjuvant-dependent enhancement of HIV env-specific antibody responses in infant rhesus macaques","volume":"92","author":"Phillips","year":"2018","journal-title":"J. Virol."},{"key":"B248","doi-asserted-by":"publisher","first-page":"29","DOI":"10.4049\/jimmunol.168.1.29","article-title":"Development and homeostasis of T cell memory in rhesus macaque","volume":"168","author":"Pitcher","year":"2002","journal-title":"J. Immunol."},{"key":"B249","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/82_2012_272","article-title":"Overview of influenza viruses","volume":"370","author":"Pleschka","year":"2013","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B250","doi-asserted-by":"publisher","first-page":"2603","DOI":"10.1056\/NEJMoa2034577","article-title":"Safety and efficacy of the BNT162b2 mRNA covid-19 vaccine","volume":"383","author":"Polack","year":"2020","journal-title":"N Engl. J. Med."},{"key":"B251","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/s41591-019-0392-8","article-title":"The repertoire of maternal anti-viral antibodies in human newborns","volume":"25","author":"Pou","year":"2019","journal-title":"Nat. Med."},{"key":"B252","doi-asserted-by":"publisher","first-page":"2064","DOI":"10.1086\/jid.2004.189.issue-11","article-title":"Protection against challenge with measles virus (MV) in infant macaques by an MV DNA vaccine administered in the presence of neutralizing antibody","volume":"189","author":"Premenko-Lanier","year":"2004","journal-title":"J. Infect. diseases."},{"key":"B253","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/S0042-6822(02)00036-3","article-title":"DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate","volume":"307","author":"Premenko-Lanier","year":"2003","journal-title":"Virology."},{"key":"B254","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1038\/nri3277","article-title":"The impact of differential antiviral immunity in children and adults","volume":"12","author":"Prendergast","year":"2012","journal-title":"Nat. Rev. Immunol."},{"key":"B255","doi-asserted-by":"publisher","first-page":"4659","DOI":"10.1073\/pnas.94.9.4659","article-title":"A transgenic mouse model for measles virus infection of the brain","volume":"94","author":"Rall","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"B256","first-page":"240","article-title":"Chikungunya infection in neonates","volume":"45","author":"Rao","year":"2008","journal-title":"Indian Pediatr."},{"key":"B257","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1203\/00006450-198305000-00006","article-title":"Influenza infection in the infant mouse","volume":"17","author":"Reuman","year":"1983","journal-title":"Pediatr. Res."},{"key":"B258","doi-asserted-by":"publisher","first-page":"6439","DOI":"10.1038\/s41467-022-33832-6","article-title":"Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection","volume":"13","author":"Reynard","year":"2022","journal-title":"Nat. Commun."},{"key":"B259","doi-asserted-by":"publisher","first-page":"6687","DOI":"10.1128\/JVI.75.14.6687-6691.2001","article-title":"Pathogenesis of influenza A (H5N1) virus infection in a primate model","volume":"75","author":"Rimmelzwaan","year":"2001","journal-title":"J. Virol."},{"key":"B260","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1637\/0005-2086-47.s3.931","article-title":"A primate model to study the pathogenesis of influenza A (H5N1) virus infection","volume":"47","author":"Rimmelzwaan","year":"2003","journal-title":"Avian Dis."},{"key":"B261","doi-asserted-by":"publisher","first-page":"4179","DOI":"10.1128\/JVI.80.8.4179-4182.2006","article-title":"Genomic sequence of rhesus cytomegalovirus 180.92: insights into the coding potential of rhesus cytomegalovirus","volume":"80","author":"Rivailler","year":"2006","journal-title":"J. Virol."},{"key":"B262","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.placenta.2011.10.003","article-title":"Restriction of placental vasculature in a non-human primate: a unique model to study placental plasticity","volume":"33","author":"Roberts","year":"2012","journal-title":"Placenta."},{"key":"B263","doi-asserted-by":"publisher","first-page":"4481","DOI":"10.1038\/s41467-023-40076-5","article-title":"Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19","volume":"14","author":"Robertson","year":"2023","journal-title":"Nat. Commun."},{"key":"B264","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.160173","article-title":"Effectiveness of CHIKV vaccine VLA1553 demonstrated by passive transfer of human sera","volume":"7","author":"Roques","year":"2022","journal-title":"JCI Insight"},{"key":"B265","doi-asserted-by":"publisher","first-page":"e83527","DOI":"10.1172\/jci.insight.83527","article-title":"Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus","volume":"2","author":"Roques","year":"2017","journal-title":"JCI Insight"},{"key":"B266","doi-asserted-by":"publisher","first-page":"e0034123","DOI":"10.1128\/mbio.00341-23","article-title":"Evidence for the role of a second fc-binding receptor in placental igG transfer in nonhuman primates","volume":"14","author":"Rosenberg","year":"2023","journal-title":"mBio."},{"key":"B267","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1186\/s12915-021-01056-7","article-title":"Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation","volume":"19","author":"Rosenkrantz","year":"2021","journal-title":"BMC Biol."},{"key":"B268","volume-title":"Cytomegalovirus: A major cause of hearign loss in children","author":"Ross KBF","year":"2008"},{"key":"B269","doi-asserted-by":"publisher","first-page":"S514","DOI":"10.1093\/infdis\/jir118","article-title":"Global distribution of measles genotypes and measles molecular epidemiology","author":"Rota","year":"2011","journal-title":"J. Infect. Dis."},{"key":"B270","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1093\/infdis\/jiu014","article-title":"Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose","volume":"209","author":"Roy","year":"2014","journal-title":"J. Infect. Dis."},{"key":"B271","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1007\/s00335-023-10005-4","article-title":"Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping","volume":"34","author":"Ruberte","year":"2023","journal-title":"Mamm Genome."},{"key":"B272","doi-asserted-by":"publisher","first-page":"9888","DOI":"10.1128\/JVI.00956-12","article-title":"Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock","volume":"86","author":"Rudd","year":"2012","journal-title":"J. Virol."},{"key":"B273","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/B978-0-12-415894-8.00038-5","article-title":"Chapter 38 - animal models of human viral diseases","volume-title":"Animal models for the study of human disease","author":"Ruiz","year":"2013"},{"key":"B274","volume-title":"The principles of human experimental technique","author":"Russell","year":"1959"},{"key":"B275","doi-asserted-by":"publisher","first-page":"3721","DOI":"10.1128\/JVI.80.8.3721-3731.2006","article-title":"Genetic analysis of simian immunodeficiency virus expressed in milk and selectively transmitted through breastfeeding","volume":"80","author":"Rychert","year":"2006","journal-title":"J. Virol."},{"key":"B276","doi-asserted-by":"publisher","first-page":"90ps27","DOI":"10.1126\/scitranslmed.3001880","article-title":"Development of newborn and infant vaccines","volume":"3","author":"Sanchez-Schmitz","year":"2011","journal-title":"Sci. Transl. Med."},{"key":"B277","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.mib.2020.05.011","article-title":"Neonatal gut microbiome and immunity","volume":"56","author":"Sanidad","year":"2020","journal-title":"Curr. Opin. Microbiol."},{"key":"B278","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.add2420","article-title":"Exacerbated Zika virus-induced neuropathology and microcephaly in fetuses of dengue-immune nonhuman primates","volume":"15","author":"Saron","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"B279","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9040306","article-title":"The potential role of nonhuman primate models to better comprehend early life immunity and maternal antibody transfer","volume":"9","author":"Sartoretti","year":"2021","journal-title":"Vaccines (Basel)."},{"key":"B280","doi-asserted-by":"publisher","first-page":"2138","DOI":"10.1016\/S0140-6736(23)00641-4","article-title":"Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind, multicentre, randomised, placebo-controlled, phase 3 trial","volume":"401","author":"Schneider","year":"2023","journal-title":"Lancet."},{"key":"B281","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1038\/s42003-024-06390-4","article-title":"Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro","volume":"7","author":"Schuller","year":"2024","journal-title":"Commun. Biol."},{"key":"B282","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/nrmicro2368","article-title":"Biology and pathogenesis of chikungunya virus","volume":"8","author":"Schwartz","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"B283","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9091014","article-title":"Special issue \u201cImmune ontogeny and vaccination in early life: how the non-human primate model can help expand the current knowledge in pediatric immunology and infectious diseases research","volume":"9","author":"Seddiki","year":"2021","journal-title":"Vaccines (Basel)."},{"key":"B284","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.595297","article-title":"Understanding early-life adaptive immunity to guide interventions for pediatric health","volume":"11","author":"Semmes","year":"2020","journal-title":"Front. Immunol."},{"key":"B285","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1038\/s41467-019-13972-y","article-title":"Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity","volume":"11","author":"Shapiro","year":"2020","journal-title":"Nat. Commun."},{"key":"B286","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.144448","article-title":"Immune perturbation following SHIV infection is greater in newborn macaques than in infants","author":"Shapiro","year":"2024","journal-title":"JCI Insight"},{"key":"B287","doi-asserted-by":"publisher","first-page":"a006841","DOI":"10.1101\/cshperspect.a006841","article-title":"Origins of HIV and the AIDS pandemic","volume":"1","author":"Sharp","year":"2011","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"B288","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1002\/jmv.25807","article-title":"COVID-19 epidemic: Disease characteristics in children","volume":"92","author":"She","year":"2020","journal-title":"J. Med. Virol."},{"key":"B289","doi-asserted-by":"publisher","first-page":"5337","DOI":"10.1016\/j.vaccine.2014.07.036","article-title":"Development of serum antibodies during early infancy in rhesus macaques: implications for humoral immune responses to vaccination at birth","volume":"32","author":"Shen","year":"2014","journal-title":"Vaccine."},{"key":"B290","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1152\/physiol.00049.2018","article-title":"Physiology in perspective: of mice and men","volume":"34","author":"Sieck","year":"2019","journal-title":"Physiol. (Bethesda)."},{"key":"B291","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1177\/0300985815620628","article-title":"Age-associated pathology in rhesus macaques (Macaca mulatta)","volume":"53","author":"Simmons","year":"2016","journal-title":"Vet. Pathol."},{"key":"B292","doi-asserted-by":"publisher","first-page":"20143085","DOI":"10.1098\/rspb.2014.3085","article-title":"Evolution of the immune system in humans from infancy to old age","volume":"282","author":"Simon","year":"2015","journal-title":"Proc. Biol. Sci."},{"key":"B293","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abq7378","article-title":"Precision adjuvants for pediatric vaccines","volume":"16","author":"Singh","year":"2024","journal-title":"Sci. Transl. Med."},{"key":"B294","doi-asserted-by":"publisher","first-page":"3003","DOI":"10.4049\/jimmunol.1400895","article-title":"Single-cell analysis of innate cytokine responses to pattern recognition receptor stimulation in children across four continents","volume":"193","author":"Smolen","year":"2014","journal-title":"J. Immunol."},{"key":"B295","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1177\/0009922816638660","article-title":"Zika virus: an explosive pandemic and a new TORCH agent","volume":"55","author":"Steele","year":"2016","journal-title":"Clin. Pediatr. (Phila)."},{"key":"B296","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1038\/s41584-019-0276-9","article-title":"Rheumatic manifestations of chikungunya: emerging concepts and interventions","volume":"15","author":"Suhrbier","year":"2019","journal-title":"Nat. Rev. Rheumatol."},{"key":"B297","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1084\/jem.20050882","article-title":"Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects","volume":"202","author":"Sylwester","year":"2005","journal-title":"J. Exp. Med."},{"key":"B298","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.bpsc.2022.03.001","article-title":"Translational utility of the nonhuman primate model","volume":"7","author":"Tarantal","year":"2022","journal-title":"Biol. Psychiatry Cognit. Neurosci. Neuroimaging."},{"key":"B299","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1086\/jid.1998.177.issue-2","article-title":"Neuropathogenesis induced by rhesus cytomegalovirus in fetal rhesus monkeys (Macaca mulatta)","volume":"177","author":"Tarantal","year":"1998","journal-title":"J. Infect. Diseases."},{"key":"B300","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1146\/annurev.pathmechdis.3.121806.154316","article-title":"The pathology of influenza virus infections","volume":"3","author":"Taubenberger","year":"2008","journal-title":"Annu. Rev. Pathol."},{"key":"B301","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1177\/00333549101250S305","article-title":"Influenza: the once and future pandemic","author":"Taubenberger","year":"2010","journal-title":"Public Health Rep."},{"key":"B302","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1080\/19420862.2019.1589852","article-title":"From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses","volume":"11","author":"Tolbert","year":"2019","journal-title":"MAbs."},{"key":"B303","doi-asserted-by":"publisher","first-page":"2364","DOI":"10.1152\/japplphysiol.00476.2004","article-title":"Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys","volume":"97","author":"Tran","year":"2004","journal-title":"J. Appl. Physiol. (1985)."},{"key":"B304","unstructured":"Neonatal mortality\n          \n          2024"},{"key":"B305","volume-title":"Companion studies to define the distribution and duration of Zika virus in non-human primates Silver Spring, MD","year":"2016"},{"key":"B306","doi-asserted-by":"publisher","first-page":"8791","DOI":"10.1128\/JVI.73.10.8791-8797.1999","article-title":"Altered virulence of vaccine strains of measles virus after prolonged replication in human tissue","volume":"73","author":"Valsamakis","year":"1999","journal-title":"J. Virol."},{"key":"B307","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1093\/infdis\/170.2.443","article-title":"Viral replication and development of specific immunity in macaques after infection with different measles virus strains","volume":"170","author":"van Binnendijk","year":"1994","journal-title":"J. Infect. Dis."},{"key":"B308","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.antiviral.2015.07.005","article-title":"Animal models of Middle East respiratory syndrome coronavirus infection","volume":"122","author":"van Doremalen","year":"2015","journal-title":"Antiviral Res."},{"key":"B309","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.2353\/ajpath.2007.070248","article-title":"Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals","volume":"171","author":"van Riel","year":"2007","journal-title":"Am. J. Pathol."},{"key":"B310","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1016\/j.vaccine.2009.11.061","article-title":"Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV","volume":"28","author":"Van Rompay","year":"2010","journal-title":"Vaccine."},{"key":"B311","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/00126334-200502010-00002","article-title":"Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV","volume":"38","author":"Van Rompay","year":"2005","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"B312","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/00126334-200502010-00002","article-title":"Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV","volume":"38","author":"Van Rompay","year":"2005","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"B313","doi-asserted-by":"publisher","first-page":"F79","DOI":"10.1097\/00002030-199809000-00001","article-title":"Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infection","volume":"12","author":"Van Rompay","year":"1998","journal-title":"AIDS."},{"key":"B314","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1086\/jid.1998.177.issue-5","article-title":"Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection","volume":"177","author":"Van Rompay","year":"1998","journal-title":"J. Infect. Dis."},{"key":"B315","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1128\/AAC.43.4.802","article-title":"9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) therapy prolongs survival of infant macaques inoculated with simian immunodeficiency virus with reduced susceptibility to PMPA","volume":"43","author":"Van Rompay","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"B316","doi-asserted-by":"publisher","first-page":"2947","DOI":"10.1128\/JVI.73.4.2947-2955.1999","article-title":"Early short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine treatment favorably alters the subsequent disease course in simian immunodeficiency virus-infected newborn Rhesus macaques","volume":"73","author":"van Rompay","year":"1999","journal-title":"J. Virol."},{"key":"B317","doi-asserted-by":"publisher","first-page":"3144","DOI":"10.1128\/AAC.00350-08","article-title":"Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects","volume":"52","author":"Van Rompay","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"B318","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/978-1-4614-2251-8_7","article-title":"Animal models of HIV transmission through breastfeeding and pediatric HIV infection","volume":"743","author":"Van Rompay","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"B319","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1097\/01.qai.0000224972.60339.7c","article-title":"Evaluation of oral tenofovir disoproxil fumarate and topical tenofovir GS-7340 to protect infant macaques against repeated oral challenges with virulent simian immunodeficiency virus","volume":"43","author":"Van Rompay","year":"2006","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"B320","doi-asserted-by":"publisher","first-page":"2381","DOI":"10.1128\/AAC.36.11.2381","article-title":"Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3\u2019-azido-3\u2019-deoxythymidine prevents SIV infection","volume":"36","author":"Van Rompay","year":"1992","journal-title":"Antimicrob. Agents Chemother."},{"key":"B321","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1128\/JVI.74.4.1767-1774.2000","article-title":"Prophylactic and therapeutic benefits of short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine (PMPA) administration to newborn macaques following oral inoculation with simian immunodeficiency virus with reduced susceptibility to PMPA","volume":"74","author":"Van Rompay","year":"2000","journal-title":"J. Virol."},{"key":"B322","doi-asserted-by":"publisher","first-page":"e1009688","DOI":"10.1371\/journal.ppat.1009688","article-title":"Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaques","volume":"17","author":"Van Rompay","year":"2021","journal-title":"PloS Pathog."},{"key":"B323","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1128\/AAC.39.1.125","article-title":"Immediate zidovudine treatment protects simian immunodeficiency virus-infected newborn macaques against rapid onset of AIDS","volume":"39","author":"Van Rompay","year":"1995","journal-title":"Antimicrob. Agents Chemother."},{"key":"B324","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1097\/00126334-200408010-00003","article-title":"The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters","volume":"36","author":"Van Rompay","year":"2004","journal-title":"J. Acquir. Immune Defic. Syndr."},{"key":"B325","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/1742-4690-9-57","article-title":"Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal","volume":"9","author":"Van Rompay","year":"2012","journal-title":"Retrovirology."},{"key":"B326","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/laban.1279","article-title":"and AIDS: contributions by non-human primate models","volume":"46","author":"Van Rompay KKA. Tackling","year":"2017","journal-title":"Lab. Anim. (NY)."},{"key":"B327","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1093\/ilar\/ilx032","article-title":"Nonhuman primate models and understanding the pathogenesis of HIV infection and AIDS","volume":"58","author":"Veazey","year":"2017","journal-title":"ILAR J."},{"key":"B328","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.coviro.2016.06.010","article-title":"Humanized mice for HIV and AIDS research","volume":"19","author":"Victor Garcia","year":"2016","journal-title":"Curr. Opin. Virol."},{"key":"B329","first-page":"25","article-title":"Seroepidemiologic studies of cytomegalovirus infection in a breeding population of rhesus macaques","volume":"44","author":"Vogel","year":"1994","journal-title":"Lab. Anim. Sci."},{"key":"B330","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ijid.2016.05.014","article-title":"Zika virus, vectors, reservoirs, amplifying hosts, and their potential to spread worldwide: what we know and what we should investigate urgently","volume":"48","author":"Vorou","year":"2016","journal-title":"Int. J. Infect. Dis."},{"key":"B331","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ijid.2017.03.006","article-title":"Global expansion of chikungunya virus: mapping the 64-year history","volume":"58","author":"Wahid","year":"2017","journal-title":"Int. J. Infect. Dis."},{"key":"B332","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1038\/s41541-024-00821-3","article-title":"Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth","volume":"9","author":"Wang","year":"2024","journal-title":"NPJ Vaccines"},{"key":"B333","doi-asserted-by":"publisher","first-page":"5358","DOI":"10.1016\/j.vaccine.2021.08.011","article-title":"Pre-existing immunity to cytomegalovirus in macaques influences human CMV vaccine responses in preclinical models","volume":"39","author":"Webster","year":"2021","journal-title":"Vaccine."},{"key":"B334","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a021469","article-title":"The chimpanzee model for hepatitis B virus infection","volume":"5","author":"Wieland","year":"2015","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"B335","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/s41586-020-2423-5","article-title":"Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2","volume":"585","author":"Williamson","year":"2020","journal-title":"Nature."},{"key":"B336","doi-asserted-by":"publisher","first-page":"5233","DOI":"10.1038\/s41467-021-25497-4","article-title":"Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding","volume":"12","author":"Wittwer","year":"2021","journal-title":"Nat. Commun."},{"key":"B337","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines5040039","article-title":"Neutralization of human cytomegalovirus entry into fibroblasts and epithelial cells","volume":"5","author":"Wussow","year":"2017","journal-title":"Vaccines (Basel)."},{"key":"B338","doi-asserted-by":"publisher","first-page":"297 e1","DOI":"10.1016\/j.ajog.2009.11.018","article-title":"Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population","volume":"202","author":"Yamamoto","year":"2010","journal-title":"Am. J. Obstet Gynecol."},{"key":"B339","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.708472","article-title":"The role of microbiota in infant health: from early life to adulthood","volume":"12","author":"Yao","year":"2021","journal-title":"Front. Immunol."},{"key":"B340","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.ijid.2020.03.073","article-title":"Pre-existing chikungunya virus neutralizing antibodies correlate with risk of symptomatic infection and subclinical seroconversion in a Philippine cohort","volume":"95","author":"Yoon","year":"2020","journal-title":"Int. J. Infect. Dis."},{"key":"B341","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01759","article-title":"Innate immunity of neonates and infants","volume":"9","author":"Yu","year":"2018","journal-title":"Front. Immunol."},{"key":"B342","doi-asserted-by":"publisher","first-page":"e01653","DOI":"10.1128\/jvi.01653-21","article-title":"Pathogenesis of wild-type-like rhesus cytomegalovirus strains following oral exposure of immune-competent rhesus macaques","volume":"96","author":"Yue","year":"2022","journal-title":"J. Virology."},{"key":"B343","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1099\/jgv.0.000455","article-title":"The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains","volume":"97","author":"Yue","year":"2016","journal-title":"J. Gen. Virol."},{"key":"B344","doi-asserted-by":"publisher","first-page":"nwad248","DOI":"10.1093\/nsr\/nwad248","article-title":"Neurogenesis in primates versus rodents and the value of non-human primate models","volume":"10","author":"Zhang","year":"2023","journal-title":"Natl. Sci. Rev."},{"key":"B345","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.152551","article-title":"A congenital CMV infection model for follow-up studies of neurodevelopmental disorders, neuroimaging abnormalities, and treatment","volume":"7","author":"Zhou","year":"2022","journal-title":"JCI Insight"},{"key":"B346","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature."},{"key":"B347","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1006\/viro.1997.8575","article-title":"and immunity in the rhesus macaque","volume":"233","author":"Zhu","year":"1997","journal-title":"Virology."},{"key":"B348","doi-asserted-by":"publisher","first-page":"e2034","DOI":"10.1002\/rmv.v29.3","article-title":"Estimation of the worldwide seroprevalence of cytomegalovirus: A systematic review and meta-analysis","volume":"29","author":"Zuhair","year":"2019","journal-title":"Rev. Med. Virol."},{"key":"B349","doi-asserted-by":"publisher","DOI":"10.1172\/JCI175824","article-title":"FDA Modernization Act 2.0: transitioning beyond animal models with human cells, organoids, and AI\/ML-based approaches","volume":"133","author":"Zushin","year":"2023","journal-title":"J. Clin. Invest."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2024.1493885\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T06:30:54Z","timestamp":1733207454000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2024.1493885\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,3]]},"references-count":349,"alternative-id":["10.3389\/fcimb.2024.1493885"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2024.1493885","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,3]]},"article-number":"1493885"}}