{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:28:29Z","timestamp":1791984509042,"version":"4.4.0"},"reference-count":152,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No.82372575"],"award-info":[{"award-number":["No.82372575"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sarcopenia, an age-related disorder marked by decreased skeletal muscle mass, strength, and function, is associated with negative health impacts in individuals and financial burdens on families and society. Studies have suggested that age-related alterations in gut microbiota may contribute to the development of sarcopenia in older people through the gut-muscle axis, thus modulation of gut microbiota may be a promising approach for sarcopenia treatment. However, the characteristic gut microbiota for sarcopenia has not been consistent across studies. Therefore, the aim of this study was to compare the diversity and compositional differences in the gut microbiota of older people with and without sarcopenia, and to identify gut microbiota biomarkers with therapeutic potential for sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Database were searched studies about the gut microbiota characteristics in older people with sarcopenia. The quality of included articles was assessed by the Newcastle-Ottawa Scale (NOS). Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for \u03b1-diversity index were estimated using a random effects model. Qualitative synthesis was conducted for \u03b2-diversity and the correlation between gut microbiota and muscle parameters. The relative abundance of the gut microbiota was analyzed quantitatively and qualitatively, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pooled estimates showed that \u03b1-diversity was significantly lower in older people with sarcopenia (SMD: -0.41, 95% CI: -0.57 to -0.26, I\u00b2: 71%, P &amp;lt; 0.00001). The findings of \u03b2-diversity varied across included studies. In addition, our study identified gut microbiota showing a potential and negative correlation with sarcopenia, such as Prevotella, Slackia, Agathobacter, Alloprevotella, Prevotella copri, Prevotellaceae sp., Bacteroides coprophilus, Mitsuokella multacida, Bacteroides massiliensis, Bacteroides coprocola Conversely, a potential and positive correlation was observed with opportunistic pathogens like Escherichia-Shigella, Eggerthella, Eggerthella lenta and Collinsella aerofaciens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This study showed that \u03b1-diversity is decreased in sarcopenia, probably predominantly due to diminished richness rather than evenness. In addition, although findings of \u03b2-diversity varied across included studies, the overall trend toward a decrease in SCFAs-producing bacteria and an increase in conditionally pathogenic bacteria. This study provides new ideas for targeting the gut microbiota for the prevention and treatment of sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Systematic review registration<\/jats:title><jats:p><jats:uri>https:\/\/www.crd.york.ac.uk\/PROSPERO\/view\/CRD42024573090<\/jats:uri>, identifier CRD42024573090.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcimb.2025.1480293","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T05:33:31Z","timestamp":1745818411000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"15","author":[{"given":"Yanqing","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfeng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2676","DOI":"10.1002\/jcsm.13342","article-title":"Altered gut microbiome, bile acid composition and metabolome in sarcopenia in liver cirrhosis","volume":"14","author":"Aliwa","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101773","article-title":"Comparison between frail and non-frail older adults\u2019 gut microbiota: A systematic review and meta-analysis","volume":"82","author":"Almeida","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"B3","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/1574-6968.12111","article-title":"Implications of the human microbiome in inflammatory bowel diseases","volume":"342","author":"Bakhtiar","year":"2013","journal-title":"FEMS\u00a0Microbiol Lett."},{"key":"B4","doi-asserted-by":"publisher","first-page":"P20","DOI":"10.3390\/nu10070890","article-title":"A vegetarian diet is a major determinant of gut microbiota composition in early pregnancy","volume":"10","author":"Barrett","year":"2018","journal-title":"Nutrients"},{"key":"B5","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1186\/s12877-016-0349-4","article-title":"Sarcopenia in daily practice: assessment and management","volume":"16","author":"Beaudart","year":"2016","journal-title":"BMC Geriatr."},{"key":"B6","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.exger.2015.05.003","article-title":"Quality of life and physical components linked to sarcopenia: The\u00a0SarcoPhAge study","volume":"69","author":"Beaudart","year":"2015","journal-title":"Exp. Gerontol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1186\/s12941-022-00527-1","article-title":"Clinical features, hospitalisation and deaths associated with monkeypox: a systematic review and meta-analysis","volume":"21","author":"Benites-Zapata","year":"2022","journal-title":"Ann. Clin. Microbiol Antimicrob"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037971","article-title":"Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model","volume":"7","author":"Bindels","year":"2012","journal-title":"PloS One"},{"key":"B9","doi-asserted-by":"publisher","first-page":"2186","DOI":"10.1016\/j.biocel.2013.06.021","article-title":"Muscle wasting: the gut microbiota as a new therapeutic target","volume":"45","author":"Bindels","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s40168-017-0296-0","article-title":"(Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease","volume":"5","author":"Buford","year":"2017","journal-title":"Microbiome"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1164.e7","DOI":"10.1016\/j.jamda.2016.09.013","article-title":"Association between sarcopenia and cognitive impairment: A systematic review and meta-analysis","volume":"17","author":"Chang","year":"2016","journal-title":"J. Am. Med. Dir Assoc"},{"key":"B12","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1002\/jcsm.12849","article-title":"Probiotic supplementation attenuates age-related sarcopenia via the gut-muscle axis in SAMP8 mice","volume":"13","author":"Chen","year":"2022","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B13","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J. Am. Med. Dir Assoc"},{"key":"B14","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1097\/cm9.0000000000002206","article-title":"Gut\u00a0microbiota and microbiota-derived metabolites in cardiovascular diseases","volume":"136","author":"Chen","year":"2023","journal-title":"Chin.\u00a0Mid. J. (Engl)"},{"key":"B15","doi-asserted-by":"publisher","first-page":"P20","DOI":"10.3390\/jof6040287","article-title":"Cork Oak Endophytic Fungi as Potential Biocontrol Agents against Biscogniauxia mediterranea and Diplodia corticola","volume":"6","author":"Costa","year":"2020","journal-title":"J. Fungi (Basel)"},{"key":"B16","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1161\/circulationaha.123.064071","article-title":"Sarcopenia and cardiovascular diseases","volume":"147","author":"Damluji","year":"2023","journal-title":"Circulation"},{"key":"B18","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1093\/ageing\/afw071","article-title":"Validation of the FNIH sarcopenia criteria and SOF frailty index as predictors of long-term mortality in ambulatory older men","volume":"45","author":"De Buyser","year":"2016","journal-title":"Age Ageing"},{"key":"B19","doi-asserted-by":"publisher","first-page":"2547s","DOI":"10.1093\/jn\/137.11.2547S","article-title":"Modulation of glucagon-like peptide 1 and energy metabolism by inulin and oligofructose: experimental data","volume":"137","author":"Delzenne","year":"2007","journal-title":"J.\u00a0Nutr."},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.656730","article-title":"Targeting the gut microbiota to improve dietary protein efficacy to mitigate sarcopenia","volume":"8","author":"de Marco Castro","year":"2021","journal-title":"Front. Nutr."},{"key":"B21","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.1194\/jlr.R036012","article-title":"The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism","volume":"54","author":"den Besten","year":"2013","journal-title":"J. Lipid Res."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1038\/s41591-018-0160-1","article-title":"Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography","volume":"24","author":"Deschasaux","year":"2018","journal-title":"Nat. Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1038\/s41564-024-01698-7","article-title":"Phytate metabolism is mediated by microbial cross-feeding in the gut microbiota","volume":"9","author":"De Vos","year":"2024","journal-title":"Nat. Microbiol"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02800","article-title":"Honokiol ameliorates high-fat-diet-induced obesity of different sexes of mice by modulating the composition of the gut microbiota","volume":"10","author":"Ding","year":"2019","journal-title":"Front. Immunol."},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124599","article-title":"Sex, body mass index, and dietary fiber intake influence the human gut microbiome","volume":"10","author":"Dominianni","year":"2015","journal-title":"PloS One"},{"key":"B26","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1096\/fj.10-164152","article-title":"Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways","volume":"25","author":"Doyle","year":"2011","journal-title":"FASEB J."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1016\/j.nut.2015.02.011","article-title":"The aromatic amino acid tryptophan stimulates skeletal muscle IGF1\/p70s6k\/mTor signaling in vivo and the expression of myogenic genes in vitro","volume":"31","author":"Dukes","year":"2015","journal-title":"Nutrition"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1099\/ijs.0.2008\/004580-0","article-title":"Proposal of a neotype strain (A1-86) for Eubacterium rectale. Request for an opinion","volume":"58","author":"Duncan","year":"2008","journal-title":"Int. J. Syst. Evol. Microbiol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1111\/j.0006-341x.2000.00455.x","article-title":"Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"B30","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1038\/s41581-023-00736-7","article-title":"Inflammation and gut dysbiosis as drivers of CKD-MBD","volume":"19","author":"Evenepoel","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"2877","DOI":"10.1093\/jn\/nxac231","article-title":"Relation between dietary protein intake and gut microbiome composition in community-dwelling older men: findings from the osteoporotic fractures in men study (MrOS)","volume":"152","author":"Farsijani","year":"2023","journal-title":"J. Nutr."},{"key":"B32","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1159\/000097979","article-title":"Patterns and correlates of muscle strength loss in older women","volume":"53","author":"Forrest","year":"2007","journal-title":"Gerontology"},{"key":"B33","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1093\/gerona\/glu057","article-title":"Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases","author":"Franceschi","year":"2014","journal-title":"J. Gerontol A Biol. Sci. Med. Sci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s12934-020-01319-y","article-title":"Metatranscriptomic analysis to define the Secrebiome, and 16S rRNA profiling of the gut microbiome in obesity and metabolic syndrome of Mexican children","volume":"19","author":"Gallardo-Becerra","year":"2020","journal-title":"Microb Cell Fact"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.2337\/db08-1637","article-title":"Butyrate improves insulin sensitivity and increases energy expenditure in mice","volume":"58","author":"Gao","year":"2009","journal-title":"Diabetes"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1093\/gerona\/glaa047","article-title":"Interactions between the aging gut microbiome and common geriatric giants: polypharmacy, frailty, and dementia","volume":"76","author":"Gemikonakli","year":"2021","journal-title":"J.\u00a0Gerontol A Biol. Sci. Med. Sci."},{"key":"B37","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1080\/19490976.2017.1406584","article-title":"Low dietary fiber intake increases Collinsella abundance in the gut microbiota of overweight and obese pregnant women","volume":"9","author":"Gomez-Arango","year":"2018","journal-title":"Gut Microbes"},{"key":"B38","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1007\/s00223-017-0345-5","article-title":"Gut microbiota contribute to age-related changes in skeletal muscle size, composition, and function: biological basis for a gut-muscle axis","volume":"102","author":"Grosicki","year":"2018","journal-title":"Calcif Tissue Int."},{"key":"B39","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s40168-024-01819-8","article-title":"Dietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism","volume":"12","author":"Han","year":"2024","journal-title":"Microbiome"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/j.clnu.2022.05.008","article-title":"Differences in the gut microbiome and reduced fecal butyrate in elders with low skeletal muscle mass","volume":"41","author":"Han","year":"2022","journal-title":"Clin. Nutr."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1926","DOI":"10.1101\/gad.1212704","article-title":"Upstream and downstream of mTOR","volume":"18","author":"Hay","year":"2004","journal-title":"Genes Dev."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat. Med."},{"key":"B43","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1080\/19490976.2017.1290756","article-title":"Dietary fiber and prebiotics and the gastrointestinal microbiota","volume":"8","author":"Holscher","year":"2017","journal-title":"Gut Microbes"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01237","article-title":"Burn\u00a0injury\u00a0leads to increase in relative abundance of opportunistic pathogens in\u00a0the\u00a0rat gastrointestinal microbiome","volume":"8","author":"Huang","year":"2017","journal-title":"Front. Microbiol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"P19","DOI":"10.3390\/biomedicines11072076","article-title":"The potential influence of uremic toxins on the homeostasis of bones and muscles in chronic kidney disease","volume":"11","author":"Hung","year":"2023","journal-title":"Biomedicines"},{"key":"B46","doi-asserted-by":"publisher","first-page":"777","DOI":"10.7326\/m14-2385","article-title":"The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations","volume":"162","author":"Hutton","year":"2015","journal-title":"Ann. Intern Med."},{"key":"B47","doi-asserted-by":"publisher","first-page":"P16","DOI":"10.3390\/nu13082727","article-title":"Malnutrition and gut microbiota in children","volume":"13","author":"Iddrisu","year":"2021","journal-title":"Nutrients"},{"key":"B48","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1136\/gutjnl-2015-310376","article-title":"Proton pump inhibitors affect the gut microbiome","volume":"65","author":"Imhann","year":"2016","journal-title":"Gut"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-016-0262-7","article-title":"Signatures of early frailty in the gut microbiota","volume":"8","author":"Jackson","year":"2016","journal-title":"Genome Med."},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.732541","article-title":"Distinctive gut microbiota in patients with overweight and obesity with dyslipidemia and its responses to long-term orlistat and ezetimibe intervention: A randomized controlled open-label trial","volume":"12","author":"Jin","year":"2021","journal-title":"Front. Pharmacol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1136\/gut.2010.223263","article-title":"Dysbiosis of the faecal microbiota in patients with Crohn\u2019s disease and their unaffected relatives","volume":"60","author":"Joossens","year":"2011","journal-title":"Gut"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1099\/00207713-50-4-1595","article-title":"Catenibacterium mitsuokai gen. nov., sp. nov., a gram-positive anaerobic bacterium isolated from human faeces","author":"Kageyama","year":"2000","journal-title":"Int. J. Syst. Evol. Microbiol"},{"key":"B53","doi-asserted-by":"publisher","first-page":"4936","DOI":"10.1039\/d3fo05420a","article-title":"Dietary supplementation with Lacticaseibacillus rhamnosus IDCC3201 alleviates sarcopenia by modulating the gut microbiota and metabolites in dexamethasone-induced models","volume":"15","author":"Kang","year":"2024","journal-title":"Food Funct."},{"key":"B54","doi-asserted-by":"publisher","first-page":"4628","DOI":"10.1038\/s41598-021-84031-0","article-title":"Alterations in intestinal microbiota diversity, composition, and function in patients with sarcopenia","volume":"11","author":"Kang","year":"2021","journal-title":"Sci. Rep."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2022.104721","article-title":"A multistrain probiotic improves handgrip strength and functional capacity in patients with COPD: A randomized controlled trial","volume":"102","author":"Karim","year":"2022","journal-title":"Arch. Gerontol Geriatr."},{"key":"B56","doi-asserted-by":"publisher","first-page":"P2","DOI":"10.1093\/ageing\/afae052","article-title":") the conceptual definition of sarcopenia: delphi consensus from the global\u00a0leadership initiative in sarcopenia (GLIS)","volume":"53","author":"Kirk","year":"2024","journal-title":"Age Ageing"},{"key":"B57","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/j.cell.2018.09.055","article-title":"Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1","volume":"175","author":"Koh","year":"2018","journal-title":"Cell"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230x-9-95","article-title":"Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel syndrome sufferers","volume":"9","author":"Krogius-Kurikka","year":"2009","journal-title":"BMC Gastroenterol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1096\/fj.00-0463","article-title":"Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB","volume":"15","author":"Langen","year":"2001","journal-title":"FASEB J."},{"key":"B60","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1111\/j.1472-765x.2004.01474.x","article-title":"In\u00a0vivo\u00a0characterization of Lactobacillus johnsonii FI9785 for use as a defined competitive exclusion agent against bacterial pathogens in poultry","volume":"38","author":"La Ragione","year":"2004","journal-title":"Lett. Appl. Microbiol"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2022.100619","article-title":"Sarcopenia-related gut microbial changes are associated with the risk of complications in people with cirrhosis","volume":"5","author":"Lee","year":"2023","journal-title":"JHEP Rep."},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2022.111927","article-title":"Sarcopenia in community-dwelling older adults is associated with the diversity and composition of the gut microbiota","volume":"167","author":"Lee","year":"2022","journal-title":"Exp. Gerontol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s40104-021-00545-7","article-title":"Evaluation of curcumin and copper acetate against Salmonella Typhimurium infection, intestinal permeability, and cecal microbiota composition in broiler chickens","volume":"12","author":"Leyva-Diaz","year":"2021","journal-title":"J. Anim Sci. Biotechnol."},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.805481","article-title":"Effects of short-chain fatty acid modulation on potentially diarrhea-causing pathogens in yaks through metagenomic sequencing","volume":"12","author":"Li","year":"2022","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1007\/s00726-017-2493-3","article-title":"A review of the relationship between the gut microbiota and amino acid metabolism","volume":"49","author":"Lin","year":"2017","journal-title":"Amino Acids"},{"key":"B66","doi-asserted-by":"publisher","first-page":"3509","DOI":"10.1080\/10408398.2020.1867054","article-title":"Gut microbiota and aging","volume":"62","author":"Ling","year":"2022","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1002\/jcsm.12784","article-title":"Understanding the gut microbiota and sarcopenia: a systematic review","volume":"12","author":"Liu","year":"2021","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.703126","article-title":"Biomarkers of gut microbiota in chronic spontaneous urticaria and symptomatic dermographism","volume":"11","author":"Liu","year":"2021","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.1002\/jcsm.13313","article-title":"Prevotella copri alleviates sarcopenia via attenuating muscle mass loss and function decline","volume":"14","author":"Liu","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B70","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1007\/s00284-013-0338-1","article-title":"Analysis of fecal Lactobacillus community structure in patients with early rheumatoid arthritis","volume":"67","author":"Liu","year":"2013","journal-title":"Curr. Microbiol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/s13073-016-0307-y","article-title":"The healthy human microbiome","volume":"8","author":"Lloyd-Price","year":"2016","journal-title":"Genome Med."},{"key":"B72","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/ggi.14661","article-title":"Changes and correlation analysis of intestinal microflora composition, inflammatory index, and skeletal muscle mass in elderly patients with sarcopenia","volume":"24","author":"Lou","year":"2024","journal-title":"Geriatr. Gerontol Int."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1574-6968.2009.01514.x","article-title":"Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine","volume":"294","author":"Louis","year":"2009","journal-title":"FEMS Microbiol Lett."},{"key":"B74","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/1462-2920.13589","article-title":"Formation of propionate and butyrate by the human colonic microbiota","volume":"19","author":"Louis","year":"2017","journal-title":"Environ. Microbiol"},{"key":"B75","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1038\/nature11550","article-title":"Diversity, stability and resilience of the human gut microbiota","volume":"489","author":"Lozupone","year":"2012","journal-title":"Nature"},{"key":"B76","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s40168-020-00900-2","article-title":"Ultrafast and accurate 16S rRNA microbial community analysis using Kraken 2","volume":"8","author":"Lu","year":"2020","journal-title":"Microbiome"},{"key":"B77","doi-asserted-by":"publisher","first-page":"1860","DOI":"10.1002\/jcsm.12788","article-title":"Human gut microbiome impacts skeletal muscle mass via gut microbial synthesis of the short-chain fatty acid butyrate among healthy menopausal women","volume":"12","author":"Lv","year":"2021","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B78","doi-asserted-by":"publisher","first-page":"4532","DOI":"10.3748\/wjg.v16.i36.4532","article-title":"Association of symptoms with gastrointestinal microbiota in irritable\u00a0bowel syndrome","volume":"16","author":"Malinen","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1136\/gutjnl-2015-309990","article-title":"The gut microbiota and host health: a new clinical frontier","volume":"65","author":"Marchesi","year":"2016","journal-title":"Gut"},{"key":"B80","doi-asserted-by":"publisher","first-page":"P5, 6, 9, 11, 24","DOI":"10.3390\/toxins13070472","article-title":"Association of sarcopenia and gut microbiota composition in older patients with advanced chronic kidney disease, investigation of the interactions with uremic toxins, inflammation and oxidative stress","volume":"13","author":"Margiotta","year":"2021","journal-title":"Toxins (Basel)"},{"key":"B81","doi-asserted-by":"publisher","first-page":"P2, 22","DOI":"10.1128\/mSystems.00144-16","article-title":"Health and disease imprinted in the time variability of the human microbiome","volume":"2","author":"Mart\u00ed","year":"2017","journal-title":"mSystems"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1415398","article-title":"The prevalence of sarcopenia and risk factors in the older adult in China: a systematic review and meta-analysis","volume":"12","author":"Meng","year":"2024","journal-title":"Front. Public Health"},{"key":"B83","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1007\/s12603-018-1058-9","article-title":"Muscle, Health and Costs: A Glance at their Relationship","volume":"22","author":"Mijnarends","year":"2018","journal-title":"J.\u00a0Nutr. Health Aging"},{"key":"B84","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1007\/s12602-018-9443-6","article-title":"Supportive role of probiotic strains in protecting rats from ovariectomy-induced cortical bone loss","volume":"11","author":"Montazeri-Najafabady","year":"2019","journal-title":"Probiotics Antimicrob Proteins"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.694217","article-title":"Inflammatory bowel diseases and sarcopenia: the role of inflammation and gut microbiota in the development of muscle failure","volume":"12","author":"Nardone","year":"2021","journal-title":"Front. Immunol."},{"key":"B86","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.freeradbiomed.2018.08.035","article-title":"Sarcopenia, frailty and their prevention by exercise","volume":"132","author":"Nascimento","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"B87","doi-asserted-by":"publisher","first-page":"P3, 24","DOI":"10.1093\/jambio\/lxac014","article-title":"The critical role of gut microbiota dysbiosis in skeletal muscle wasting: a systematic review","volume":"134","author":"Nikkhah","year":"2023","journal-title":"J. Appl. Microbiol"},{"key":"B88","doi-asserted-by":"publisher","first-page":"P20, 24","DOI":"10.3390\/nu12092677","article-title":"Energy gap between doubly labeled water-based energy expenditure and calculated energy intake from recipes and plate waste, and subsequent weight changes in elderly residents in Japanese long-term care facilities: CLEVER study","volume":"12","author":"Nishida","year":"2020","journal-title":"Nutrients"},{"key":"B89","doi-asserted-by":"publisher","first-page":"P2, 24","DOI":"10.3390\/nu13124499","article-title":"Exercise and nutrition impact on osteoporosis and sarcopenia-the incidence of osteosarcopenia: A narrative review","volume":"13","author":"Papadopoulou","year":"2021","journal-title":"Nutrients"},{"key":"B90","doi-asserted-by":"publisher","first-page":"2494","DOI":"10.1111\/mec.16394","article-title":"Distinct microbiota composition and fermentation products indicate functional compartmentalization in the hindgut of a marine herbivorous fish","volume":"31","author":"Pardesi","year":"2022","journal-title":"Mol. Ecol."},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2023.1127041","article-title":"Characteristics of the fecal microbiome and metabolome in older patients with heart failure and sarcopenia","volume":"13","author":"Peng","year":"2023","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B92","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1002\/jcsm.12783","article-title":"Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta-analysis","volume":"13","author":"Petermann-Rocha","year":"2022","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B93","doi-asserted-by":"publisher","first-page":"P5, 6, 11, 24","DOI":"10.3390\/nu12010065","article-title":"Gut microbial, inflammatory and metabolic signatures in older people with physical frailty and sarcopenia: results from the BIOSPHERE study","volume":"12","author":"Picca","year":"2019","journal-title":"Nutrients"},{"key":"B94","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1016\/j.clnu.2019.01.028","article-title":"The decline in muscle strength and muscle quality in relation to metabolic derangements in adult women with obesity","volume":"38","author":"Poggiogalle","year":"2019","journal-title":"Clin. Nutr."},{"key":"B95","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.1111\/liv.14876","article-title":"Characterization of the gut-liver-muscle axis in cirrhotic patients with sarcopenia","volume":"41","author":"Ponziani","year":"2021","journal-title":"Liver Int."},{"key":"B96","doi-asserted-by":"publisher","first-page":"P19, 24","DOI":"10.3390\/ijms23010483","article-title":"Gut microbiota as a source of uremic toxins","volume":"23","author":"Popkov","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B97","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/s41522-021-00248-x","article-title":"Western and non-western gut microbiomes reveal new roles of Prevotella in carbohydrate metabolism and mouth-gut axis","volume":"7","author":"Prasoodanan","year":"2021","journal-title":"NPJ Biofilms Microbiomes"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.572912","article-title":"Antibiotics as major disruptors of gut microbiota","volume":"10","author":"Ramirez","year":"2020","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101744","article-title":"Differential gut microbiota and intestinal permeability between frail and healthy older adults: A systematic review","volume":"82","author":"Rashidah","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"B100","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1615\/CritRevEukaryotGeneExpr.2017019712","article-title":"Role of interleukin-6 in development of insulin resistance and type 2 diabetes mellitus","volume":"27","author":"Rehman","year":"2017","journal-title":"Crit. Rev. Eukaryot Gene Expr"},{"key":"B101","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1038\/ismej.2014.14","article-title":"Phylogenetic distribution of three pathways for propionate production within the human gut microbiota","volume":"8","author":"Reichardt","year":"2014","journal-title":"Isme J."},{"key":"B102","doi-asserted-by":"publisher","first-page":"241","DOI":"10.5487\/tr.2018.34.3.241","article-title":"Lactobacillus aggravate bile duct ligation-induced liver inflammation and fibrosis in mice","volume":"34","author":"Roh","year":"2018","journal-title":"Toxicol. Res."},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-016-0303-2","article-title":"Evaluation of sarcopenia in patients with distal radius fractures","volume":"12","author":"Roh","year":"2017","journal-title":"Arch. Osteoporos"},{"key":"B104","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/j.cmet.2020.03.003","article-title":"Microbiota-derived metabolites suppress arthritis by amplifying aryl-hydrocarbon receptor activation in regulatory B cells","volume":"31","author":"Rosser","year":"2020","journal-title":"Cell Metab."},{"key":"B105","doi-asserted-by":"publisher","first-page":"E866","DOI":"10.1152\/ajpendo.00243.2018","article-title":"Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans","volume":"316","author":"Sachs","year":"2019","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftv096","article-title":"Microbiota-mitochondria inter-talk: consequence for microbiota-host interaction","volume":"74","author":"Saint-Georges-Chaumet","year":"2016","journal-title":"Pathog Dis."},{"key":"B107","doi-asserted-by":"publisher","first-page":"e35","DOI":"10.1086\/500214","article-title":"Lactobacillus bacteremia, species identification, and antimicrobial susceptibility of 85 blood isolates","volume":"42","author":"Salminen","year":"2006","journal-title":"Clin. Infect. Dis."},{"key":"B108","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1053\/j.gastro.2007.11.059","article-title":"Microbial influences in inflammatory bowel diseases","volume":"134","author":"Sartor","year":"2008","journal-title":"Gastroenterology"},{"key":"B109","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3390\/nu10020255","article-title":"l-carnitine supplementation in older women. A pilot study on aging skeletal muscle mass and function","volume":"10","author":"Sawicka","year":"2018","journal-title":"Nutrients"},{"key":"B110","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1111\/1574-6941.12186","article-title":"Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro","volume":"87","author":"Scott","year":"2014","journal-title":"FEMS Microbiol Ecol."},{"key":"B111","doi-asserted-by":"publisher","first-page":"P16, 24","DOI":"10.3390\/nu12010222","article-title":"Effects of synbiotic supplement on human gut microbiota, body composition and weight loss in obesity","volume":"12","author":"Sergeev","year":"2020","journal-title":"Nutrients"},{"key":"B112","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s40101-016-0121-7","article-title":"Lifestyle and geographic insights into the distinct gut microbiota in elderly women from two different geographic locations","volume":"35","author":"Shin","year":"2016","journal-title":"J. Physiol. Anthropol"},{"key":"B113","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/19490976.2021.1893113","article-title":"SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota","volume":"13","author":"Sokol","year":"2021","journal-title":"Gut Microbes"},{"key":"B114","doi-asserted-by":"publisher","first-page":"16731","DOI":"10.1073\/pnas.0804812105","article-title":"Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients","volume":"105","author":"Sokol","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"B115","doi-asserted-by":"publisher","first-page":"P21, 24","DOI":"10.3390\/nu13062045","article-title":"The effects of lifestyle and diet on gut microbiota composition, inflammation and muscle performance in our aging society","volume":"13","author":"Strasser","year":"2021","journal-title":"Nutrients"},{"key":"B116","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.arr.2018.04.004","article-title":"Dysbiosis of gut microbiota and microbial metabolites in Parkinson\u2019s disease","volume":"45","author":"Sun","year":"2018","journal-title":"Ageing Res. Rev."},{"key":"B117","doi-asserted-by":"publisher","first-page":"595","DOI":"10.2217\/fmb.11.31","article-title":"Eggerthella lenta bacteremia in a Crohn\u2019s disease patient after ileocecal resection","volume":"6","author":"Thota","year":"2011","journal-title":"Future Microbiol"},{"key":"B118","doi-asserted-by":"publisher","first-page":"P5, 7, 9, 11, 16, 18, 24","DOI":"10.3390\/ijms21238946","article-title":"The gut-muscle axis in older subjects with low muscle mass and performance: A proof of concept study exploring fecal microbiota composition and function with shotgun metagenomics sequencing","volume":"21","author":"Ticinesi","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"B119","doi-asserted-by":"publisher","first-page":"P2, 9, 24","DOI":"10.3390\/nu11071633","article-title":"Gut microbiota, muscle mass and function in aging: A focus on physical frailty and sarcopenia","volume":"11","author":"Ticinesi","year":"2019","journal-title":"Nutrients"},{"key":"B120","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1038\/s41564-018-0123-9","article-title":"Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies","volume":"3","author":"Tramontano","year":"2018","journal-title":"Nat. Microbiol"},{"key":"B121","doi-asserted-by":"publisher","first-page":"P19, 24","DOI":"10.3390\/proteomes8040028","article-title":"Short-chain fatty acids modulate metabolic pathways and membrane lipids in prevotella bryantii B(1)4","volume":"8","author":"Trautmann","year":"2020","journal-title":"Proteomes"},{"key":"B122","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.arr.2017.01.001","article-title":"Gut microbiota: A player in aging and a target for anti-aging intervention","volume":"35","author":"Vaiserman","year":"2017","journal-title":"Ageing Res. Rev."},{"key":"B123","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/19490976.2020.1849998","article-title":"From correlation to causality: the case of Subdoligranulum","volume":"12","author":"Van Hul","year":"2020","journal-title":"Gut Microbes"},{"key":"B124","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1038\/s41586-020-2269-x","article-title":"Statin therapy is associated with lower prevalence of gut microbiota dysbiosis","volume":"581","author":"Vieira-Silva","year":"2020","journal-title":"Nature"},{"key":"B125","doi-asserted-by":"publisher","first-page":"858","DOI":"10.3390\/nu3100858","article-title":"Regulation of\u00a0inflammation by short chain fatty acids","volume":"3","author":"Vinolo","year":"2011","journal-title":"Nutrients"},{"key":"B126","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1038\/ismej.2010.118","article-title":"Dominant and diet-responsive groups of bacteria within the human colonic microbiota","volume":"5","author":"Walker","year":"2011","journal-title":"Isme J."},{"key":"B127","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1111\/acel.12387","article-title":"The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging","volume":"14","author":"Walsh","year":"2015","journal-title":"Aging Cell"},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.842153","article-title":"Lactobacillus suppresses tumorigenesis of oropharyngeal cancer via enhancing anti-tumor immune response","volume":"10","author":"Wang","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"B129","doi-asserted-by":"publisher","first-page":"P5, 7, 9, 10, 25","DOI":"10.3389\/fcimb.2021.711884","article-title":"Characteristics of fecal microbiota and machine learning strategy for fecal invasive biomarkers in pediatric inflammatory bowel disease","volume":"11","author":"Wang","year":"2021","journal-title":"Front. Cell Infect. Microbiol"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.3390\/nu15051266","article-title":"Bifidobacterium as a potential biomarker of sarcopenia in elderly women","volume":"15","author":"Wang","year":"2023","journal-title":"Nutrients"},{"key":"B131","doi-asserted-by":"publisher","first-page":"2340","DOI":"10.1002\/jcsm.13037","article-title":"Population-based metagenomics analysis reveals altered gut microbiome in sarcopenia: data from the Xiangya Sarcopenia Study","volume":"13","author":"Wang","year":"2022","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.858851","article-title":"Polyunsaturated fatty acids level and bone mineral density: A two-sample Mendelian randomization study","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"B133","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1053\/j.gastro.2017.05.022","article-title":"Intestinal epithelial sirtuin 1 regulates intestinal inflammation during aging in mice by altering the intestinal microbiota","volume":"153","author":"Wellman","year":"2017","journal-title":"Gastroenterology"},{"key":"B134","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1126\/science.1208344","article-title":"Linking long-term dietary patterns with gut microbial enterotypes","volume":"334","author":"Wu","year":"2011","journal-title":"Science"},{"key":"B135","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1515\/tjb-2021-0197","article-title":"The composition of the gut microbiome in patients with sarcopenia","volume":"47","author":"Wu","year":"2022","journal-title":"Turkish J. Biochem."},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.788178","article-title":"Plasma tumor necrosis factor-\u03b1 is associated with sarcopenia in elderly individuals residing in agricultural and pastoral areas of Xinjiang, China","volume":"9","author":"Wumaer","year":"2022","journal-title":"Front. Med. (Lausanne)"},{"key":"B137","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1099\/ijs.0.005900-0","article-title":"Gordonibacter pamelaeae gen. nov., sp. nov., a new member of the Coriobacteriaceae isolated from a patient with Crohn\u2019s disease, and reclassification of Eggerthella hongkongensis Lau et\u00a0al. 2006 as Paraeggerthella hongkongensis gen. nov., comb. nov","volume":"59","author":"W\u00fcrdemann","year":"2009","journal-title":"Int. J. Syst. Evol. Microbiol"},{"key":"B138","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s40168-022-01255-6","article-title":"The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids","volume":"10","author":"Xiao","year":"2022","journal-title":"Microbiome"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.746998","article-title":"Causal relationship between gut microbiota and autoimmune diseases: A two-sample mendelian randomization study","volume":"12","author":"Xu","year":"2021","journal-title":"Front. Immunol."},{"key":"B140","doi-asserted-by":"publisher","first-page":"3674","DOI":"10.1038\/s41598-022-07810-3","article-title":"Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease","volume":"12","author":"Yamamoto","year":"2022","journal-title":"Sci. Rep."},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2023.105063","article-title":"Relationships between sarcopenia, nutrient intake, and gut microbiota in Chinese community-dwelling older women","volume":"113","author":"Yan","year":"2023","journal-title":"Arch. Gerontol Geriatr."},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.03125","article-title":"Modulation of gut microbial community and metabolism by dietary glycyl-glutamine supplementation may favor weaning transition in piglets","volume":"10","author":"Yan","year":"2019","journal-title":"Front. Microbiol"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1017147","article-title":"Multi-omics analyses reveal the specific changes in gut metagenome and serum metabolome of patients with polycystic ovary syndrome","volume":"13","author":"Yang","year":"2022","journal-title":"Front. Microbiol"},{"key":"B144","doi-asserted-by":"publisher","first-page":"e1800014","DOI":"10.1002\/mnfr.201800014","article-title":"Effects of prebiotic fiber xylooligosaccharide in adenine-induced nephropathy in mice","volume":"62","author":"Yang","year":"2018","journal-title":"Mol. Nutr. Food Res."},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2021.154712","article-title":"Role of the gut microbiota in type 2 diabetes and related diseases","volume":"117","author":"Yang","year":"2021","journal-title":"Metabolism"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.874021","article-title":"Comprehensive analysis of the relationships between the gut microbiota and fecal metabolome in individuals with primary Sjogren\u2019s syndrome by 16S rRNA sequencing and LC-MS-based metabolomics","volume":"13","author":"Yang","year":"2022","journal-title":"Front. Immunol."},{"key":"B147","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1002\/jcsm.12411","article-title":"Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis","volume":"10","author":"Yeung","year":"2019","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.01595","article-title":"Cecropin A alleviates inflammation through modulating the gut microbiota of C57BL\/6 mice with DSS-induced IBD","volume":"10","author":"Zhai","year":"2019","journal-title":"Front. Microbiol"},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101739","article-title":"Gut microbiota as a promising therapeutic target for age-related sarcopenia","volume":"81","author":"Zhang","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2024.112376","article-title":"Alterations in the diversity, composition and function of the gut microbiota in Uyghur\u00a0individuals with sarcopenia","volume":"187","author":"Zhang","year":"2024","journal-title":"Exp. Gerontol"},{"key":"B151","doi-asserted-by":"publisher","DOI":"10.3390\/nu14132778","article-title":"A comparison between dietary consumption status and healthy dietary pattern among adults aged 55 and older in China","volume":"14","author":"Zhang","year":"2022","journal-title":"Nutrients"},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2023.112287","article-title":"High-throughput sequencing analysis of the characteristics of the gut microbiota in aged patients with sarcopenia","volume":"182","author":"Zhang","year":"2023","journal-title":"Exp. Gerontol"}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2025.1480293\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T05:33:31Z","timestamp":1745818411000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2025.1480293\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,28]]},"references-count":152,"alternative-id":["10.3389\/fcimb.2025.1480293"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2025.1480293","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,28]]},"article-number":"1480293"}}