{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T17:22:16Z","timestamp":1793467336808,"version":"4.5.0"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cell. Infect. Microbiol."],"abstract":"<jats:p>\n                    We evaluated the presence of antibodies against\n                    <jats:italic>Orthonairovirus haemorrhagiae<\/jats:italic>\n                    , formerly Crimean-Congo haemorrhagic fever virus (CCHFV) in the serum of podolic cattle from southern Italy. A subset of 20 sera (18 positive and 2 negative) from the initial 670 bovine samples screened by commercial ELISA kit were further evaluated by indirect ELISA and virus neutralization tests. Across the three serological assays, antibodies against CCHFV were detected in a proportion of samples, though the results were not fully concordant and varied according to the assay applied. These findings highlight the need for multiple tests to more accurately assess CCHFV circulation in free-range cattle, particularly in non-endemic areas, and emphasize the importance of careful interpretation when relying on serology alone.\n                  <\/jats:p>","DOI":"10.3389\/fcimb.2026.1810497","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T05:33:40Z","timestamp":1776749620000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Serological insights of Crimean-Congo haemorrhagic fever virus in podolic cattle bred in Italy"],"prefix":"10.3389","volume":"16","author":[{"given":"Donato Antonio","family":"Raele","sequence":"first","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Fischer","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institute, Institute of Novel and Emerging Infectious Diseases, Federal Research Institute for Animal Health","place":["Greifswald, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Holzerland","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institute, Institute of Novel and Emerging Infectious Diseases, Federal Research Institute for Animal Health","place":["Greifswald, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Bost","sequence":"additional","affiliation":[{"name":"Friedrich-Loeffler-Institute, Institute of Novel and Emerging Infectious Diseases, Federal Research Institute for Animal Health","place":["Greifswald, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Scaltrito","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Parisi","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Belluscio","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Mattea","family":"D\u2019Antuono","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Caprarella","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Narducci","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goffredo","family":"Sarti","sequence":"additional","affiliation":[{"name":"Azienda Sanitaria Locale, SIAV-A","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Sordillo","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Di Donato","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale dell\u2019Abruzzo e del Molise \u201cG. Caporale\u201d","place":["Teramo, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Assunta","family":"Cafiero","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Cavaliere","sequence":"additional","affiliation":[{"name":"Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata","place":["Foggia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.antiviral.2013.07.006","article-title":"Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity","volume":"100","author":"Bente","year":"2013","journal-title":"Antiviral Res."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0331875","article-title":"First detection of Crimean-Congo hemorrhagic fever antibodies in cattle and wildlife of southern continental France: investigation of explanatory factors","volume":"20","author":"Bernard","year":"2025","journal-title":"PLoS One"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.932304","article-title":"Systematic review on Crimean-Congo hemorrhagic fever enzootic cycle and factors favoring virus transmission: special focus on France, an apparently free-disease area in Europe","volume":"9","author":"Bernard","year":"2022","journal-title":"Front. 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Psychol."}],"container-title":["Frontiers in Cellular and Infection Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2026.1810497\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T05:33:40Z","timestamp":1776749620000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2026.1810497\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":13,"alternative-id":["10.3389\/fcimb.2026.1810497"],"URL":"https:\/\/doi.org\/10.3389\/fcimb.2026.1810497","relation":{},"ISSN":["2235-2988"],"issn-type":[{"value":"2235-2988","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]},"article-number":"1810497"}}