{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:07:31Z","timestamp":1785575251013,"version":"3.56.0"},"reference-count":14,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"DOI":"10.3389\/fcvm.2020.563448","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T10:27:57Z","timestamp":1601029677000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Case Report First-in-Man Method Description: Left Ventricular Unloading With iVAC2L During Veno-Arterial Extracorporeal Membrane Oxygenation: From Veno-Arterial Extracorporeal Membrane Oxygenation to ECMELLA to EC-iVAC\u00ae"],"prefix":"10.3389","volume":"7","author":[{"given":"Carsten","family":"Tsch\u00f6pe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Alogna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Faragli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Klingel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunther","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten Wolfgang","family":"Heilmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"B. Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Spillmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1510\/icvts.2009.220335","article-title":"Extracorporeal membrane oxygenation to support adult patients with cardiac failure: predictive factors of 30-day mortality","volume":"10","author":"Formica","year":"2010","journal-title":"Interact CardioVasc Thoracic Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1093\/eurheartj\/ehz552","article-title":"Invasive left ventricle pressure-volume analysis: overview and practical clinical implications","volume":"41","author":"Bastos","year":"2019","journal-title":"Eur Heart J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"60","DOI":"10.2217\/fca-2019-0060","article-title":"PulseCath iVAC2L\u2014next generation pulsatile mechanical circulatory support","volume":"16","author":"Bastos","year":"2020","journal-title":"Future Cardiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"835","DOI":"10.4244\/EIJV11I7A168","article-title":"The PulseCath iVAC 2L left ventricular assist device: conversion to a percutaneous transfemoral approach","volume":"11","author":"Van Mieghem","year":"2015","journal-title":"EuroIntervention"},{"key":"B5","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s12265-018-9820-2","article-title":"Mechanical unloading by fulminant myocarditis: LV-IMPELLA, ECMELLA, BI-PELLA, and PROPELLA concepts","volume":"12","author":"Tsch\u00f6pe","year":"2019","journal-title":"J Cardiovasc Transl Res"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2164","DOI":"10.1093\/eurheartj\/ehz124","article-title":"Mode-of-action of the PROPELLA concept in fulminant myocarditis","volume":"40","author":"Spillmann","year":"2019","journal-title":"Eur Heart J"},{"key":"B7","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jacc.2008.05.065","article-title":"A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction","volume":"52","author":"Seyfarth","year":"2008","journal-title":"J Am Coll Cardiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"464135","DOI":"10.1155\/2015\/464135","article-title":"Impella induced massive hemolysis: reemphasizing echocardiographic guidance for correct placement","volume":"2015","author":"Cardozo","year":"2015","journal-title":"Case Rep Cardiol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1002\/ccd.24280","article-title":"Severe hemolysis associated with use of the Impella LP 2.5 mechanical assist device","volume":"80","author":"Sibbald","year":"2012","journal-title":"Catheter Cardiovasc Interv"},{"key":"B10","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1016\/j.jacc.2009.09.018","article-title":"Supported high-risk percutaneous coronary intervention with the Impella 2.5 device the Europella registry","volume":"54","author":"Sjauw","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1097\/PCC.0000000000001709","article-title":"Hemolysis during pediatric extracorporeal membrane oxygenation: associations with circuitry, complications, and mortality","volume":"19","author":"Dalton","year":"2018","journal-title":"Pediatr Crit Care Med"},{"key":"B12","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.healun.2013.08.019","article-title":"Hemolysis in left ventricular assist device: a retrospective analysis of outcomes","volume":"33","author":"Ravichandran","year":"2014","journal-title":"J Heart Lung Transpl."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e0227793","DOI":"10.1371\/journal.pone.0227793","article-title":"Factors associated with hemolysis during extracorporeal membrane oxygenation (ECMO)-Comparison of VA- versus VV ECMO","volume":"15","author":"Appelt","year":"2020","journal-title":"PLoS ONE."},{"key":"B14","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/MAT.0b013e31829f9bb3","article-title":"Rotary pumps and diminished pulsatility: do we need a pulse?","volume":"59","author":"Soucy","year":"2013","journal-title":"ASAIO J"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcvm.2020.563448\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T10:27:59Z","timestamp":1601029679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fcvm.2020.563448\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,25]]},"references-count":14,"alternative-id":["10.3389\/fcvm.2020.563448"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2020.563448","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,25]]},"article-number":"563448"}}