{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T16:41:23Z","timestamp":1788799283799,"version":"build-2803163510"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T00:00:00Z","timestamp":1610323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>The coronavirus disease 2019 (COVID-19) pandemic outbreak, caused by severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) is affecting people worldwide representing a public health emergency. The effect of concomitant COVID-19 on patients who underwent cardiac surgery using cardiopulmonary bypass (CPB) is still undefined. Both SARS-Cov-2 infection and CPB can develop a cytokines storm and haemostatic disarrangements leading to acute respiratory distress syndrome (ARDS) and post-perfusion lung syndrome, respectively. SARS-Cov-2 infection may trigger and exacerbate post-inflammatory state after CPB resulting in higher risk of post-surgical adverse outcomes. International guidelines lack to provide standard management protocols for pre-operative COVID-19 patients requiring non-deferrable cardiac surgery intervention. We present a report of a successful coronary artery bypass grafting (CABG) emergency operation in a COVID-19 patient, who presented unstable angina and coronary artery dissection during cardiac catheterization and percutaneous transluminal coronary angioplasty (PTCA).<\/jats:p>","DOI":"10.3389\/fcvm.2020.620610","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T02:15:34Z","timestamp":1610417734000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Case Report: Emergency CABG Following Failure of PTCA in a COVID-19 Patient"],"prefix":"10.3389","volume":"7","author":[{"given":"Silvia","family":"Romiti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Totaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amalia","family":"Laderchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Peruzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattia","family":"Vinciguerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,1,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"104361","DOI":"10.1016\/j.meegid.2020.104361","article-title":"Sars-CoV-2 and black population: ACE2 as shield or blade?","volume":"84","author":"Vinciguerra","year":"2020","journal-title":"Infect Genet Evol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.3390\/jcm9072095","article-title":"Atherosclerosis as pathogenetic substrate for Sars-Cov2 cytokine storm","volume":"9","author":"Vinciguerra","year":"2020","journal-title":"J Clin Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"109209","DOI":"10.1016\/j.ejrad.2020.109209","article-title":"COVID-19 pneumonia: diagnostic and prognostic role of CT based on a retrospective analysis of 214 consecutive patients from Paris, France","volume":"131","author":"Guillo","year":"2020","journal-title":"Eur J Radiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1016\/j.chest.2019.05.028","article-title":"Preoperative evaluation of patients with interstitial lung disease","volume":"156","author":"Patel","year":"2019","journal-title":"Chest."},{"key":"B5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0140-6736(20)31182-X","article-title":"Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study","volume":"396","author":"Nepogodiev","year":"2020","journal-title":"Lancet."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436","article-title":"Dexamethasone in hospitalized patients with Covid-19 \u2014 preliminary report","author":"Horby","year":"2020","journal-title":"N Engl J Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"e437","DOI":"10.1016\/S2665-9913(20)30121-1","article-title":"Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia","volume":"2","author":"McGonagle","year":"2020","journal-title":"Lancet Rheumatol."},{"key":"B8","first-page":"284","article-title":"Cardiovascular risk in COVID-19 infection","volume":"10","author":"Lubrano","year":"2020","journal-title":"Am J Cardiovasc Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"3100","DOI":"10.1093\/eurheartj\/ehaa400","article-title":"Multivessel spontaneous coronary artery dissection presenting in a patient with severe acute SARS-CoV-2 respiratory infection","volume":"41","author":"Gasso","year":"2020","journal-title":"Eur Heart J."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2812","DOI":"10.1007\/s00415-020-09984-0","article-title":"Bilateral carotid artery dissection in a SARS-CoV-2 infected patient: causality or coincidence?","volume":"267","author":"Morassi","year":"2020","journal-title":"J Neurol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"e405","DOI":"10.1016\/j.athoracsur.2020.04.008","article-title":"Acute type A aortic dissection during COVID-19 outbreak","volume":"110","author":"Fukuhara","year":"2020","journal-title":"Ann Thorac Surg."},{"key":"B12","doi-asserted-by":"publisher","first-page":"170","DOI":"10.2174\/157489012803832829","article-title":"Routine use of corticosteroids to prevent inflammation response in cardiac surgery","volume":"7","author":"Nebelsiek","year":"2012","journal-title":"Recent Patents Cardiovasc. 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