{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T09:17:07Z","timestamp":1772183827893,"version":"3.50.1"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p><jats:italic>Streptococcus bovis\/Streptococcus equinus<\/jats:italic> complex (SBSEC) is a group of <jats:italic>non-enterococcal group D Streptococci<\/jats:italic> that colonizes both humans and animals. Due to gastrointestinal disease, they can switch in opportunistic pathogens passing through intestinal mucosal barrier and may cause bacteremia and distant organs damage. Despite infective endocarditis (IE), extra-cardiac manifestations of organs damage include osteoarticular infections, meningitis, and biliary infections among others; moreover, the association with colonic pathological lesions has been largely described. <jats:italic>Streptococcus alactolyticus<\/jats:italic> as a species included in SBSEC may share pathophysiological similarities, although it represents an extremely rare cause of distant organ infections, being reported in literature as causative agent of IE in only two other cases. We describe a case of 69-year-old male admitted to our institution due to mild\u2013moderate dyspnea and fever, affected by cervico-brachialgia for 3 weeks. <jats:italic>Streptococcus alactolyticus<\/jats:italic> was identified as causative agent of IE on the mitral valve, causing severe regurgitation.<\/jats:p>","DOI":"10.3389\/fcvm.2021.648213","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T05:00:20Z","timestamp":1619672420000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Case Report: Streptococcus alactolyticus as a Rare Pathogen of Mitral Endocarditis"],"prefix":"10.3389","volume":"8","author":[{"given":"Mattia","family":"Vinciguerra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Santamaria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Romiti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizar","family":"D'Abramo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianmarco","family":"Toto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"De 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