{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:49:25Z","timestamp":1753890565134,"version":"3.41.2"},"reference-count":5,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>This study assessed the basic working principle to measure aortic annulus resistance during balloon inflation for transcatheter aortic valve implantation (TAVI), by acquisition of pressure-volume curve for a guided semi-automatic implantation. A modular bench-system was used which allows the incremental inflation of valvuloplasty balloons by means of a stepper-motor driven linear axis with simultaneous recording of the pressure changes inside the system. Different porcine aortic xenografts were assessed by use of a non-compliant valvuloplasty balloon. In a second step transcatheter aortic stents were implanted inside target sized xenografts. The recorded pressure volume-curves showed that the system can accurately differentiate between different xenografts and assess the quality of the tissue rendering real-time analysis of pressure-volume curves during balloon-inflation possible, which has the potential to optimize the implantation procedure by direct adaptation to the patient specific anatomy and characteristics. Further investigations and development are warranted.<\/jats:p>","DOI":"10.3389\/fcvm.2021.665029","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T04:22:02Z","timestamp":1619756522000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Proof of Concept: Measuring Aortic Annulus Resistance by Means of Pressure-Volume Curves During Balloon Inflation to Guide Transcatheter Aortic Valve Implantation"],"prefix":"10.3389","volume":"8","author":[{"given":"Timoth\u00e9e","family":"Noterdaeme","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Gesenhues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Vogt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Massberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaus","family":"Marx","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1056\/nejmoa1814052","article-title":"Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients","volume":"380","author":"Mack","year":"2019","journal-title":"N Engl J Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1093\/eurheartj\/ehx785","article-title":"Pacemaker implantation rate after transcatheter aortic valve implantation with early and new-generation devices: a systematic review","volume":"39","author":"van Rosendael","year":"2018","journal-title":"Eur Heart J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e003326","DOI":"10.1161\/CIRCINTERVENTIONS.115.003326","article-title":"Transcatheter aortic valve implantation compared with surgical aortic valve replacement in low-risk patients","volume":"9","author":"Rosato","year":"2016","journal-title":"Circulation."},{"key":"B4","doi-asserted-by":"publisher","first-page":"519","DOI":"10.4244\/EIJY15M08_02","article-title":"Does frame geometry play a role in aortic regurgitation after medtronic CoreValve implantation?","volume":"12","author":"Rodr\u00edguez-Olivares","year":"2016","journal-title":"EuroIntervention."},{"key":"B5","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s12265-019-09877-2","article-title":"The impact of size and position of a mechanical expandable transcatheter aortic valve: novel insights through computational modelling and simulation","volume":"12","author":"Rocatello","year":"2019","journal-title":"J Cardiovasc Trans Res."}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2021.665029\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T04:22:04Z","timestamp":1619756524000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2021.665029\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":5,"alternative-id":["10.3389\/fcvm.2021.665029"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2021.665029","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2021,4,30]]},"article-number":"665029"}}