{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:42Z","timestamp":1791410922294,"version":"4.3.3"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p><jats:bold>Objectives:<\/jats:bold> To analyze the predictors of pericardial effusion (PE) during the perioperative period of the left atrial appendage closure procedure in our center.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A total of 624 consecutive patients with non-valvular AF undergoing LAAC from May 2014 to October 2019 were involved in this study. Patients were divided into groups depending on whether they showed no PE, intraoperative PE or postoperative PE. We analyzed the predictors of PE during the perioperative period of the LAAC procedure.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> (1) Of the 624 patients in our population (age 68.2 \u00b1 9.1 years, 63% male, CHA2DS2-VASc score 3.4 \u00b1 1.6), 30 patients experienced PE in the perioperative period, including 10 intraoperative PE and 20 postoperative PE. (2) A total of 26 (86.6%) patients had mild PE. 4 (13.4%) patients had pericardial tamponade, 2 (6.7%) of which were intraoperative, and the other 2 (6.7%) postoperative. (3) Significant differences were measured in relation to female sex, intraoperative time, combined procedures, changes in sinus rhythm, device retrieval times and duration of hospitalization between 2 groups (no PE occurred, intraoperative PE), <jats:italic>P<\/jats:italic> values were 0.039, 0.024, 0.004, 0.015, 0.003 and 0.039.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Female sex, paroxysmal AF, changing in sinus rhythm, device retrieval times and intraoperative time all had a positive association with PE during the perioperative period.<\/jats:p>","DOI":"10.3389\/fcvm.2021.678460","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T05:04:37Z","timestamp":1627880677000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Pericardial Effusion During the Perioperative Period for Left Atrial Appendage 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