{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:49:40Z","timestamp":1753890580172,"version":"3.41.2"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T00:00:00Z","timestamp":1624579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012832","name":"Okinaka Memorial Institute for Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012832","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> Adaptive servo-ventilation (ASV) devices are designed to suppress central respiratory events, and therefore effective for sleep-disordered breathing (SDB) in patients with heart failure (HF) and provide information about their residual respiratory events. However, whether the apnea-hypopnea index (AHI), determined by the ASV device AutoSet CS (ASC), correlates with the AHI calculated by polysomnography (PSG) in patients with HF and SDB remains to be evaluated.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Consecutive patients with SDB titrated on ASC were included in the study. We assessed the correlation between AHI determined by manual scoring during PSG (AHI-PSG) and that determined by the ASC device (AHI-ASC) during an overnight session.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Thirty patients with HF and SDB (age, 68.8 \u00b1 15.4 years; two women; left ventricular ejection fraction, 53.8 \u00b1 17.9%) were included. The median AHI in the diagnostic study was 28.4 events\/h, including both obstructive and central respiratory events. During the titration, ASC markedly suppressed the respiratory events (AHI-PSG, 3.3 events\/h), while the median AHI-ASC was 12.8 events\/h. We identified a modest correlation between AHI-PSG and AHI-ASC (<jats:italic>r<\/jats:italic> = 0.36, <jats:italic>p<\/jats:italic> = 0.048). The Brand-Altman plot indicated that the ASC device overestimated the AHI, and a moderate agreement was observed with PSG.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> There was only a modest correlation between AHI-PSG and AHI-ASC. The discrepancy may be explained by either the central respiratory events that occur during wakefulness or the other differences between PSG and ASC in the detected respiratory events. Therefore, clinicians should consider this divergence when assessing residual respiratory events using ASC.<\/jats:p>","DOI":"10.3389\/fcvm.2021.680053","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T04:14:41Z","timestamp":1624594481000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the Apnea-Hypopnea Index Determined by Adaptive Servo-Ventilation Devices in Patients With Heart Failure and Sleep-Disordered Breathing"],"prefix":"10.3389","volume":"8","author":[{"given":"Satomi","family":"Imanari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kasagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fusae","family":"Kawana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sugao","family":"Ishiwata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Narui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takatoshi","family":"Kasai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,6,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"2154","DOI":"10.1161\/01.CIR.97.21.2154","article-title":"Sleep apnea in 81 ambulatory male patients with stable heart failure. Types and their prevalences, consequences, and presentations","volume":"97","author":"Javaheri","year":"1998","journal-title":"Circulation."},{"key":"B2","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.1161\/CIRCULATIONAHA.106.683482","article-title":"Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial (CANPAP)","volume":"115","author":"Arzt","year":"2007","journal-title":"Circulation."},{"key":"B3","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1136\/thx.2010.146522","article-title":"Complex sleep apnoea in congestive heart failure","volume":"66","author":"Bitter","year":"2011","journal-title":"Thorax."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1378\/chest.07-1715","article-title":"Efficacy of adaptive servoventilation in treatment of complex and central sleep apnea syndromes","volume":"132","author":"Allam","year":"2007","journal-title":"Chest."},{"key":"B5","doi-asserted-by":"publisher","first-page":"146","DOI":"10.5664\/jcsm.27763","article-title":"Evaluation of the apnea-hypopnea index determined by the S8 auto-CPAP, a continuous positive airway pressure device, in patients with obstructive sleep apnea-hypopnea syndrome","volume":"6","author":"Ueno","year":"2010","journal-title":"J Clin Sleep Med."},{"volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications","year":"2007","author":"Iber","key":"B6"},{"key":"B7","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.1001\/archinte.166.16.1716","article-title":"Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea","volume":"166","author":"Arzt","year":"2006","journal-title":"Arch Intern Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1007\/s11897-014-0250-4","article-title":"Altered breathing syndrome in heart failure: newer insights and treatment options","volume":"12","author":"Tomita","year":"2015","journal-title":"Curr Heart Fail Rep."},{"key":"B10","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1590\/S0100-879X2008000300007","article-title":"Breathing disorders in congestive heart failure: gender, etiology and mortality","volume":"41","author":"Silva","year":"2008","journal-title":"Braz J Med Biol Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"103286","DOI":"10.1016\/j.resp.2019.103286","article-title":"Sleep duration and architecture during ASV for central sleep apnoea in systolic heart failure","volume":"271","author":"Roder","year":"2020","journal-title":"Respir Physiol Neurobiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1164\/ajrccm\/143.3.657","article-title":"Rate of oxyhemoglobin desaturation in obstructive versus nonobstructive apnea","volume":"143","author":"Fletcher","year":"1991","journal-title":"Am Rev Respir Dis."},{"key":"B13","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.ijcard.2008.06.028","article-title":"Risk factors and prognostic value of daytime Cheyne-Stokes respiration in chronic heart failure patients","volume":"137","author":"Poletti","year":"2009","journal-title":"Int J Cardiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1378\/chest.07-0121","article-title":"Daytime Cheyne-Stokes respiration in ambulatory patients with severe congestive heart failure is associated with increased mortality","volume":"132","author":"Brack","year":"2007","journal-title":"Chest."},{"key":"B15","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/s00392-018-1239-x","article-title":"Adaptive servo-ventilation to treat central sleep apnea in heart failure with reduced ejection fraction: the Bad Oeynhausen prospective ASV registry","volume":"107","author":"Oldenburg","year":"2018","journal-title":"Clin Res Cardiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/s13063-020-4091-z","article-title":"Rationale and design of the randomised Treatment of sleep apnoea Early After Myocardial infarction with Adaptive Servo-Ventilation trial (TEAM-ASV I)","volume":"21","author":"Fox","year":"2020","journal-title":"Trials."}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2021.680053\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T04:14:44Z","timestamp":1624594484000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2021.680053\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,25]]},"references-count":16,"alternative-id":["10.3389\/fcvm.2021.680053"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2021.680053","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2021,6,25]]},"article-number":"680053"}}