{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:55:33Z","timestamp":1761519333899,"version":"3.41.2"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Infectious control measures during the COVID-19 pandemic have led to the propensity toward telemedicine. This study examined the impact of telemedicine during the pandemic on the long-term outcomes of ST-segment elevation myocardial infarction (STEMI) patients.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This study included 288 patients admitted 1 year before the pandemic (October 2018\u2013December 2018) and during the pandemic (January 2020\u2013March 2020) eras, and survived their index STEMI admission. The follow-up period was 1 year. One-year primary safety endpoint was all-cause mortality. Secondary safety endpoints were cardiac readmissions for unplanned revascularisation, non-fatal myocardial infarction, heart failure, arrythmia, unstable angina. Major adverse cardiovascular events (MACE) was defined as the composite outcome of each individual safety endpoint.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Despite unfavorable in-hospital outcomes among patients admitted during the pandemic compared to pre-pandemic era, both groups had similar 1-year all-cause mortality (11.2 vs. 8.5%, respectively, <jats:italic>p<\/jats:italic> = 0.454) but higher cardiac-related (14.1 vs. 5.1%, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) and heart failure readmissions in the pandemic vs. pre-pandemic groups (7.1 vs. 1.7%, <jats:italic>p<\/jats:italic> = 0.037). Follow-up was more frequently conducted via teleconsultations (1.2 vs. 0.2 per patient\/year, <jats:italic>p<\/jats:italic> = 0.001), with reduction in physical consultations (2.1 vs. 2.6 per patient\/year, <jats:italic>p<\/jats:italic> = 0.043), during the pandemic vs. pre-pandemic era. Majority achieved guideline-directed medical therapy (GDMT) during pandemic vs. pre-pandemic era (75.9 vs. 61.6%, <jats:italic>p<\/jats:italic> = 0.010). Multivariable Cox regression demonstrated achieving medication target doses (HR 0.387, 95% CI 0.164\u20130.915, <jats:italic>p<\/jats:italic> = 0.031) and GDMT (HR 0.271, 95% CI 0.134\u20130.548, <jats:italic>p<\/jats:italic> &amp;lt; 0.001) were independent predictors of lower 1-year MACE after adjustment.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The pandemic has led to the wider application of teleconsultation, with increased adherence to GDMT, enhanced medication target dosing. Achieving GDMT was associated with favorable long-term prognosis.<\/jats:p>","DOI":"10.3389\/fcvm.2021.755822","type":"journal-article","created":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T05:27:22Z","timestamp":1634880442000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Post-ST-Segment Elevation Myocardial Infarction Follow-Up Care During the COVID-19 Pandemic and the Possible Benefit of Telemedicine: An Observational Study"],"prefix":"10.3389","volume":"8","author":[{"given":"Audrey A. Y.","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas W. 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