{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:28:33Z","timestamp":1791246513606,"version":"4.1.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:00:00Z","timestamp":1641340800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"Objective:<\/jats:bold> We aimed to determine the cardiorespiratory responses during, and adaptations to, high-intensity interval training (HIIT) prescribed using ratings of perceived exertion (RPE) in patients after myocardial infarction (MI) during early outpatient cardiac rehabilitation (CR).<\/jats:p>Methods:<\/jats:bold> We prospectively recruited 29 MI patients after percutaneous coronary intervention who began CR within 2 weeks after hospital discharge. Eleven patients (seven men; four women; age: 61 \u00b1 11 yrs) who completed \u226524 supervised HIIT sessions with metabolic gas exchange measured during HIIT once weekly for 8 weeks and performed pre- and post- CR cardiopulmonary exercise tests were included in the study. Each HIIT session consisted of 5\u20138 high-intensity intervals [HIIs, 1-min RPE 14\u201317 (Borg 6\u201320 scale)] and low-intensity intervals (LIIs, 4-min RPE &lt; 12). Metabolic gas exchange, heart rate (HR), and blood pressure during HIIT were measured.<\/jats:p>Results:<\/jats:bold> The mean oxygen uptake (V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2<\/jats:sub>) during HIIs across 88 sessions of HIITs [91 (14)% of V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2peak<\/jats:sub>, median (interquartile range, IQR)] was significantly higher than the lower limit of target V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2<\/jats:sub> zone (75% of V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2peak<\/jats:sub>) recommended for the HII (p<\/jats:italic> &lt; 0.001). Exercise intensity during RPE-prescribed HIITs, determined as %V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2peak<\/jats:sub>, was highly repeatable with intra-class correlations of 0.95 (95% CI 0.86\u2013 0.99, p<\/jats:italic> &lt; 0.001). For cardiorespiratory adaptations from the first to the last session of HIIT, treadmill speed, treadmill grade, treadmill power, V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2HII<\/jats:sub>, %V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2peak<\/jats:sub>, and VE<\/jats:sub> during HIIs were increased (all p<\/jats:italic> &lt; 0.05), while no difference was found for HR, %HRpeak<\/jats:sub> and systolic blood pressure (all p<\/jats:italic> &gt; 0.05). V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2peak<\/jats:sub> increased by an average of 9% from pre-CR to post-CR. No adverse events occurred.<\/jats:p>Conclusion:<\/jats:bold> Our results demonstrate that HIIT can be effectively prescribed using RPE in MI patients during early outpatient CR. Participation in RPE-prescribed HIIT increases exercise workload and V<\/mml:mtext>\u02d9<\/mml:mo><\/mml:mover>O<\/mml:mtext><\/mml:mrow><\/mml:math><\/jats:inline-formula>2<\/jats:sub> during exercise training without increased perception of effort or excessive increases in heart rate or blood pressure.<\/jats:p>","DOI":"10.3389\/fcvm.2021.772815","type":"journal-article","created":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T08:39:13Z","timestamp":1641371953000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Cardiorespiratory Responses During High-Intensity Interval Training Prescribed by Rating of Perceived Exertion in Patients After Myocardial Infarction Enrolled in Early Outpatient Cardiac Rehabilitation"],"prefix":"10.3389","volume":"8","author":[{"given":"Yaoshan","family":"Dun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane 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