{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:54:58Z","timestamp":1753890898803,"version":"3.41.2"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Different definitions of contrast-associated acute kidney injury (CA-AKI) have different predictive effects on prognosis. However, few studies explored the relationship between these definitions and long-term prognosis in patients with congestive heart failure (CHF). Thus, we aimed to evaluate this association and compared the population attributable risks (PAR) of different CA-AKI definitions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study enrolled 2,207 consecutive patients with CHF undergoing coronary angiography (CAG) in Guangdong Provincial People's Hospital. Two different definitions of CA-AKI were used: CA-AKI<jats:sub>A<\/jats:sub> was defined as an increase \u2265.5 mg\/dl or &amp;gt; 25% in serum creatinine (SCr) from baseline within 72 h after CAG, and CA-AKI<jats:sub>B<\/jats:sub> was defined as an increase of \u2265.3 mg\/dl or &amp;gt; 50% in SCr from baseline within 48 h after CAG. Kaplan-Meier methods and Cox regression were applied to evaluate the association between CA-AKI with long-term mortality. Population attributable risk (PAR) of different definitions for long-term prognosis was also calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the 3.8-year median follow-up (interquartile range 2.1-6), the overall long-term mortality was 24.9%, and the long-term mortality in patients with the definitions of CA-AKI<jats:sub>A<\/jats:sub> and CA-AKI<jats:sub>B<\/jats:sub> were 30.4% and 34.3%, respectively. We found that CA-AKI<jats:sub>A<\/jats:sub> (HR: 1.44, 95% CI 1.19-1.74) and CA-AKI<jats:sub>B<\/jats:sub> (HR: 1.48, 95% CI 1.21-1.80) were associated with long-term mortality. The PAR was higher for CA-AKI<jats:sub>A<\/jats:sub> (9.6% vs. 8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggested that CA-AKI was associated with long-term mortality in patients with CHF irrespective of its definitions. The CA-AKI<jats:sub>A<\/jats:sub> was a much better definition of CA-AKI in patients with CHF due to its higher PAR. For these patients, cardiologists should pay more attention to the presence of CA-AKI, especially CA-AKI<jats:sub>A<\/jats:sub>.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2022.763656","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T06:45:36Z","timestamp":1651041936000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison Between Two Definitions of Contrast-Associated Acute Kidney Injury in Patients With Congestive Heart Failure"],"prefix":"10.3389","volume":"9","author":[{"given":"Bo","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiying","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanqiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyou","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhubin","family":"Lun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziling","family":"Mai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liwei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziqing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengfei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongquan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiqun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.ahj.2004.09.055","article-title":"Inhospital and 1-year mortality of patients who develop worsening renal function following acute ST-elevation myocardial infarction","volume":"1502","author":"Goldberg","year":"2005","journal-title":"Am Heart J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.annemergmed.2015.04.028","article-title":"Major adverse events one year after acute kidney injury after contrast-enhanced computed tomography","volume":"663","author":"Mitchell","year":"2015","journal-title":"Ann Emerg Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.ijcard.2016.11.019","article-title":"Association of contrast-induced nephropathy with risk of adverse clinical outcomes in patients with cardiac catheterization: from the CINC-J study","volume":"227","author":"Sato","year":"2017","journal-title":"Int J Cardiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1016\/j.jacc.2004.06.068","article-title":"A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation","volume":"447","author":"Mehran","year":"2004","journal-title":"J Am Coll Cardiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1253\/circj.cj-13-0574","article-title":"Clinical predictors of contrast-induced acute kidney injury in patients undergoing emergency versus elective percutaneous coronary intervention","volume":"781","author":"Abe","year":"2014","journal-title":"Circ J."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.1007\/s00330-011-2225-0","article-title":"Contrast induced nephropathy: updated ESUR contrast media safety committee guidelines","volume":"2112","author":"Stacul","year":"2011","journal-title":"Eur Radiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1253\/circj.cj-14-0117","article-title":"Admission hyperglycemia is an independent predictor of acute kidney injury in patients with acute myocardial infarction","volume":"786","author":"Moriyama","year":"2014","journal-title":"Circ J."},{"key":"B8","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.ijcard.2016.02.086","article-title":"A comparison between two different definitions of contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention","volume":"210","author":"Centola","year":"2016","journal-title":"Int J Cardiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"100522","DOI":"10.1016\/j.ijcha.2020.100522","article-title":"A comparison between different definitions of contrast-induced acute kidney injury for long-term mortality in patients with acute myocardial infarction","volume":"28","author":"Lei","year":"2020","journal-title":"Int J Cardiol Heart Vasc."},{"key":"B10","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1186\/s12872-020-01778-6","article-title":"A comparison between two different definitions of contrast-associated acute kidney injury for long-term mortality in patients with diabetes undergoing coronary angiography: a prospective cohort study","volume":"201","author":"Lun","year":"2020","journal-title":"BMC Cardiovasc Disord."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1016\/j.jacc.2009.10.015","article-title":"2009 focused updates: ACC\/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC\/AHA\/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"5423","author":"Kushner","year":"2009","journal-title":"J Am Coll Cardiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.jacc.2012.06.004","article-title":"2012 ACCF\/AHA focused update of the guideline for the management of patients with unstable angina\/non-ST-elevation myocardial infarction (updating the 2007 guideline and replacing the 2011 focused update): a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"607","author":"Jneid","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1093\/eurheartj\/ehu422","article-title":"ESC\/EACTS myocardial revascularization guidelines 2014","volume":"3546","author":"Kolh","year":"2014","journal-title":"Eur Heart J."},{"key":"B14","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS Guidelines on myocardial revascularization","volume":"402","author":"Neumann","year":"2019","journal-title":"Eur Heart J."},{"key":"B15","first-page":"5","article-title":"Report of a WHO scientific group","volume":"405","author":"Nutritional","year":"1968","journal-title":"World Health Organ Tech Rep Ser"},{"key":"B16","doi-asserted-by":"publisher","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group","volume":"1306","author":"Levey","year":"1999","journal-title":"Ann Intern Med."},{"key":"B17","first-page":"S1","volume":"392","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"B18","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/s0735-1097(02)02663-3","article-title":"Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community","volume":"411","author":"Manjunath","year":"2003","journal-title":"J Am Coll Cardiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e033017","DOI":"10.1136\/bmjopen-2019-033017","article-title":"Rationale and design of the Web-basEd soCial media tecHnology to improvement in Adherence to dual anTiplatelet Therapy following Drug-Eluting Stent Implantation (WECHAT): protocol for a randomised controlled study","volume":"101","author":"Sun","year":"2020","journal-title":"BMJ Open."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jcin.2013.06.016","article-title":"Contemporary incidence, predictors, and outcomes of acute kidney injury in patients undergoing percutaneous coronary interventions: insights from the NCDR Cath-PCI registry","volume":"71","author":"Tsai","year":"2014","journal-title":"JACC Cardiovasc Interv."},{"key":"B21","doi-asserted-by":"publisher","first-page":"23738","DOI":"10.18632\/oncotarget.25315","article-title":"Optimal hydration volume among high-risk patients with advanced congestive heart failure undergoing coronary angiography","volume":"934","author":"Chen","year":"2018","journal-title":"Oncotarget."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1470320320979795","DOI":"10.1177\/1470320320979795","article-title":"Impact of contrast-induced acute kidney injury on the association between renin-angiotensin system inhibitors and long-term mortality in heart failure patients","volume":"214","author":"Lei","year":"2020","journal-title":"J Renin Angiotensin Aldosterone Syst."},{"key":"B23","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1097\/fjc.0000000000000502","article-title":"Safe hydration volume to prevent contrast-induced acute kidney injury and worsening heart failure in patients with heart failure and preserved ejection fraction after cardiac catheterization","volume":"703","author":"Bei","year":"2017","journal-title":"J Cardiovasc Pharmacol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"e6259","DOI":"10.1097\/md.0000000000006259","article-title":"Association of N-terminal pro-brain natriuretic peptide with contrast-induced acute kidney injury and long-term mortality in patients with heart failure and mid-range ejection fraction: An observation study","volume":"9610","author":"Wang","year":"2017","journal-title":"Medicine (Baltimore)."},{"key":"B25","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s10557-015-6635-0","article-title":"Contrast-induced acute kidney injury: an update","volume":"302","author":"Chalikias","year":"2016","journal-title":"Cardiovasc Drugs Ther."}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.763656\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T06:45:40Z","timestamp":1651041940000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.763656\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":25,"alternative-id":["10.3389\/fcvm.2022.763656"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2022.763656","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2022,4,27]]},"article-number":"763656"}}