{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:04:27Z","timestamp":1788260667333,"version":"build-2803163510"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Rotational atherectomy (RA) is an indispensable tool used for calcified lesion preparation in percutaneous coronary intervention (PCI). However, use of RA in the setting of acute myocardial infarction (AMI) is challenged with limited clinical data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to retrospectively investigate the procedural results, periprocedural complications, and clinical outcomes of RA in patients with AMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All possible consecutive patients who received RA in AMI from January 2009 to March 2018 in a single tertiary center were analyzed retrospectively. Patients without AMI during the study period were also enrolled for comparison.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 121 patients with AMI (76.0 \u00b1 10.8 years, 63.6% males) and 290 patients without AMI were recruited. Among the AMI group, 81% of patients had non-ST-elevation myocardial infarction (NSTEMI) and 14% presented with cardiogenic shock. RA could be completed in 98.8% of patients in the AMI group and 98.3% in the non-AMI group (\n                      <jats:italic>p<\/jats:italic>\n                      = 1.00). The periprocedural complication rates were comparable between the AMI and non-AMI groups. The risks of in-hospital, 30-day, 90-day, and 1-year cardiovascular major adverse cardiac events (CV MACE) were significantly higher in the AMI group compared with the non-AMI group (in-hospital 13.2 vs. 2.8%,\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001; 30-day 14.2 vs. 4.5%,\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001; 90-day 20.8 vs. 6.9%,\n                      <jats:italic>p<\/jats:italic>\n                      &amp;lt; 0.001; 1-year 30.8 vs. 19.1%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.01). AMI at initial presentation and cardiogenic shock were predictors for both in-hospital CV MACE and 1-year CV MACE in multivariable binary logistic regression analysis. Other predictors for 1-year CV MACE included serum creatinine level and triple vessel disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>RA in patients with AMI is feasible with a high procedural completion rate and acceptable periprocedural complications. Given unstable hemodynamics and complex coronary anatomy, the in-hospital and 1-year MACE rates remained higher in patients with AMI compared with patients without AMI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fcvm.2022.846564","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T01:48:45Z","timestamp":1647568125000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["The Procedural and Clinical Outcomes of Rotational Atherectomy in Patients Presenting With Acute Myocardial Infarction"],"prefix":"10.3389","volume":"9","author":[{"given":"Yu-Wei","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hung","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Shou","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Yen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Jhong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzu-Hsiang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kae-Woei","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsun-Jui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Lieng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/eurheartj\/ehy855","article-title":"2018 esc\/eacts guidelines on myocardial revascularization","volume":"40","author":"Neumann","year":"2019","journal-title":"Eur Heart J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001038","article-title":"2021 acc\/aha\/scai guideline for coronary artery revascularization: a report of the american college of cardiology\/american heart association joint committee on clinical practice guidelines","volume":"145","author":"Lawton","year":"2022","journal-title":"Circulation."},{"key":"B3","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1093\/eurheartj\/ehy285","article-title":"Clinical use of intracoronary imaging. Part 1: guidance and optimization of coronary interventions an expert consensus document of the European association of percutaneous cardiovascular interventions","volume":"39","author":"Raber","year":"2018","journal-title":"Eur Heart J."},{"key":"B4","doi-asserted-by":"publisher","first-page":"e007448","DOI":"10.1161\/CIRCINTERVENTIONS.118.007448","article-title":"North american expert review of rotational atherectomy","volume":"12","author":"Sharma","year":"2019","journal-title":"Circ Cardiovasc Interv."},{"key":"B5","doi-asserted-by":"publisher","first-page":"30","DOI":"10.4244\/EIJV11I1A6","article-title":"European expert consensus on rotational atherectomy","volume":"11","author":"Barbato","year":"2015","journal-title":"EuroIntervention."},{"key":"B6","doi-asserted-by":"publisher","first-page":"e632","DOI":"10.4244\/EIJV12I5A103","article-title":"Rotational atherectomy of undilatable coronary stents: Stentablation, a clinical perspective and recommendation","volume":"12","author":"Edes","year":"2016","journal-title":"EuroIntervention."},{"key":"B7","doi-asserted-by":"publisher","first-page":"E817","DOI":"10.1002\/ccd.29215","article-title":"An algorithmic approach to balloon-uncrossable coronary lesions","volume":"97","author":"Elrayes","year":"2021","journal-title":"Catheter Cardiovasc Interv."},{"key":"B8","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1002\/ccd.29116","article-title":"Impact of lesion preparation strategies on outcomes of left main pci: The excel trial","volume":"98","author":"Beohar","year":"2021","journal-title":"Catheter Cardiovasc Interv."},{"key":"B9","first-page":"217","article-title":"Rotablation in the treatment of high-risk patients with heavily calcified left-main coronary lesions","volume":"10","author":"Chiang MH Yi","year":"2013","journal-title":"J Geriatr Cardiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/joic.12515","article-title":"Feasibility and clinical outcomes of rotational atherectomy for heavily-calcified side branches of complex coronary bifurcation lesions in the real-world practice of the drug-eluting stent era","volume":"31","author":"Chen","year":"2018","journal-title":"J Interv Cardiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1016\/j.amjcard.2019.01.054","article-title":"Usefulness of atherectomy in chronic total occlusion interventions (from the progress-cto registry)","volume":"123","author":"Xenogiannis","year":"2019","journal-title":"Am J Cardiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1002\/ccd.25945","article-title":"Clinical predictors of mortality following rotational atherectomy and stent implantation in high-risk patients: a single center experience","volume":"86","author":"Edes","year":"2015","journal-title":"Catheter Cardiovasc Interv."},{"key":"B13","first-page":"428","article-title":"The characteristics and clinical outcomes of rotational atherectomy under intra-aortic balloon counterpulsation assistance for complex and very high-risk coronary interventions in contemporary practice: An eight-year experience from a tertiary center","volume":"36","author":"Chen","year":"2020","journal-title":"Acta Cardiol Sin."},{"key":"B14","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1161\/01.CIR.98.8.742","article-title":"Activation of platelets in platelet-rich plasma by rotablation is speed-dependent and can be inhibited by abciximab (c7e3 fab; reopro)","volume":"98","author":"Williams","year":"1998","journal-title":"Circulation."},{"key":"B15","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1111\/jth.12016","article-title":"Periprocedural variations of platelet reactivity during elective percutaneous coronary intervention","volume":"10","author":"Mangiacapra","year":"2012","journal-title":"J Thromb Haemost."},{"key":"B16","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.jcin.2016.11.059","article-title":"Management of no-reflow phenomenon in the catheterization laboratory","volume":"10","author":"Rezkalla","year":"2017","journal-title":"JACC Cardiovasc Interv."},{"key":"B17","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1093\/eurheartj\/ehy856","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"40","author":"Thygesen","year":"2019","journal-title":"Eur Heart J."},{"key":"B18","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1016\/j.gheart.2012.08.001","article-title":"Third universal definition of myocardial infarction","volume":"33","author":"Thygesen","year":"2012","journal-title":"Eur Heart J."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1002\/ccd.27213","article-title":"Coronary atherectomy is associated with improved procedural and clinical outcomes among patients with calcified coronary lesions: insights from the va cart program","volume":"91","author":"Armstrong","year":"2018","journal-title":"Catheter Cardiovasc Interv."},{"key":"B20","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/ccd.28099","article-title":"Impact of calcification on percutaneous coronary intervention: Mace-trial 1-year results","volume":"94","author":"Sharma","year":"2019","journal-title":"Catheter Cardiovasc Interv."},{"key":"B21","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1136\/heartjnl-2020-316745","article-title":"Use of intracoronary imaging to guide optimal percutaneous coronary intervention procedures and outcomes","volume":"107","author":"Mintz","year":"2021","journal-title":"Heart."},{"key":"B22","doi-asserted-by":"publisher","first-page":"e008686","DOI":"10.1161\/CIRCINTERVENTIONS.120.008686","article-title":"Intravascular imaging-guided percutaneous coronary intervention: a universal approach for optimization of stent implantation","volume":"13","author":"Shlofmitz","year":"2020","journal-title":"Circ Cardiovasc Interv."},{"key":"B23","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1002\/ccd.27842","article-title":"Feasibility and clinical outcome of rotational atherectomy in patients presenting with an acute coronary syndrome","volume":"93","author":"Allali","year":"2019","journal-title":"Catheter Cardiovasc Interv."},{"key":"B24","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.jjcc.2017.10.012","article-title":"Acute coronary syndrome - still a valid contraindication to perform rotational atherectomy?","volume":"71","author":"Kubler","year":"2018","journal-title":"Early and one-year outcomes J Cardiol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.4244\/EIJ-D-15-00485","article-title":"Rotational atherectomy in acute coronary syndrome: Early and midterm outcomes from a multicentre registry","volume":"12","author":"Iannaccone","year":"2016","journal-title":"EuroIntervention."},{"key":"B26","doi-asserted-by":"publisher","first-page":"e305","DOI":"10.4244\/EIJ-D-19-01129","article-title":"Clinical outcomes of pci with rotational atherectomy: the european multicentre euro4c registry","volume":"16","author":"Bouisset","year":"2020","journal-title":"EuroIntervention."},{"key":"B27","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.amjcard.2020.12.040","article-title":"Effect of sex on outcomes of coronary rotational atherectomy percutaneous coronary intervention (from the european multicenter euro4c registry)","volume":"143","author":"Bouisset","year":"2021","journal-title":"Am J Cardiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1894389","DOI":"10.1155\/2020\/1894389","article-title":"Incidence and mechanisms of coronary perforations during rotational atherectomy in modern practice","volume":"2020","author":"Wang","year":"2020","journal-title":"J Interv Cardiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.jcma.2017.02.009","article-title":"Clinical outcomes of percutaneous coronary intervention with rotablation in patients with acute or recent myocardial infarction","volume":"80","author":"Wang","year":"2017","journal-title":"J Chin Med Assoc."}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.846564\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T01:48:49Z","timestamp":1647568129000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.846564\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,18]]},"references-count":29,"alternative-id":["10.3389\/fcvm.2022.846564"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2022.846564","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,18]]},"article-number":"846564"}}