{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T02:00:10Z","timestamp":1791165610033,"version":"4.1.0"},"reference-count":45,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970248"],"award-info":[{"award-number":["81970248"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Hydrogen sulfide (H<jats:sub>2<\/jats:sub>S) is known for its unpleasant odor and severe toxicity. However, an in-depth study of H<jats:sub>2<\/jats:sub>S showed that it can be used as an important messenger, which can play important physiological and pathological roles <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic>. In recent years, the application of H<jats:sub>2<\/jats:sub>S in the field of cardiac preservation has attracted the interest and attention of scholars worldwide. H<jats:sub>2<\/jats:sub>S plays an effective and protective role in cardiac ischemia\/reperfusion injury through antioxidant, anti-inflammatory, and antiapoptotic mechanisms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study is to analyze the current scientific achievements on the application of H<jats:sub>2<\/jats:sub>S in the field of cardiac preservation and to provide new ideas for further research.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>TS = (\u201chydrogen sulfide\u201d OR \u201chydrogen sulfide\u201d) AND TS = (\u201ccardiac\u201d OR \u201cheart\u201d OR \u201cmyocardium\u201d OR \u201chearts\u201d) AND TS = (\u201creperfusion\u201d or \u201ctransplantation\u201d or \u201cimplanted\u201d or \u201ctransplant\u201d or \u201cimplantation\u201d or \u201cmigration\u201d or \u201cpreservation\u201d or \u201cgrafting\u201d OR \u201cischemia\u201d OR \u201cperfusion\u201d or \u201cconservation\u201d or \u201cpreserve\u201d or \u201creservation\u201d) AND DT = (Article OR Review) AND LA = (English) were used as search strategies for data collection from the Science Citation Index-Expanded database of the Web of Science Core Collection. CiteSpace 5.8. R3 and Microsoft Office Excel 2019 were used for data analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 429 related articles were included, and the total number of articles showed a fluctuating upward trend. We used CiteSpace 5.8. R3 and Microsoft Excel 2019 to evaluate and visualize the results, analyzing institutions, countries, journals, authors, co-cited references, and keywords.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As increasing evidence shows that H<jats:sub>2<\/jats:sub>S plays an indispensable role in the field of cardiac preservation, its mechanistic research and clinical application may become the main focus of future research.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2022.941374","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T09:22:26Z","timestamp":1673256146000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Bibliometric evaluation of 2011\u20132021 publications on hydrogen sulfide in heart preservation research"],"prefix":"10.3389","volume":"9","author":[{"given":"Mingcong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol Rev."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1111\/pce.12073","article-title":"Hydrogen sulfide: environmental factor or signalling molecule?","volume":"36","author":"Lisjak","year":"2013","journal-title":"Plant Cell Environ."},{"key":"B3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.bcp.2017.11.019","article-title":"Gasotransmitter hydrogen sulfide signaling in neuronal health and disease","volume":"149","author":"Paul","year":"2018","journal-title":"Biochem Pharmacol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.3389\/fphar.2019.01568","article-title":"Role of endothelial dysfunction in cardiovascular diseases: the link between inflammation and hydrogen sulfide","volume":"10","author":"Sun","year":"2020","journal-title":"Front Pharmacol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1002\/bjs.8956","article-title":"Effects of hydrogen sulphide in an experimental model of renal ischaemia-reperfusion injury","volume":"99","author":"Hunter","year":"2012","journal-title":"Br J Surg."},{"key":"B6","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1038\/nrd4433","article-title":"Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter","volume":"14","author":"Wallace","year":"2015","journal-title":"Nat Rev Drug Discov."},{"key":"B7","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.phrs.2015.07.032","article-title":"Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation","volume":"100","author":"Roviezzo","year":"2015","journal-title":"Pharmacol Res."},{"key":"B8","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/0005-2744(74)90140-5","article-title":"Characterization of human cystathionine beta-synthase. 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