{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T19:50:24Z","timestamp":1770234624941,"version":"3.49.0"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The UEFA 2020 European Football Championship held in multiple cities across Europe from June 11 to July 11, 2021, was won by Italy, providing an opportunity to examine the relationship between emotional stress and the incidence of acute cardiovascular events (ACE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Cardiovascular hospitalizations in the Cardiac Care Units of 49 hospital networks in Italy were assessed by emergency physicians during the UEFA Euro 2020 Football Championship. We compared the events that occurred during matches involving Italy with events that occurred during the remaining days of the championship as the control period. ACE was assessed in 1,235 patients. ACE during the UEFA Euro 2020 Football Championship semifinal and final, the most stressful matches ended with penalties and victory of the Italian team, were assessed. A significant increase in the incidence of Takotsubo Syndrome (TTS) by a factor of 11.41 (1.6\u2013495.1, <jats:italic>P<\/jats:italic> &amp;lt; 0.003), as compared with the control period, was demonstrated during the semifinal and final, whereas no differences were found in the incidence of ACS [IRR 0.93(0.74\u20131.18), <jats:italic>P<\/jats:italic> = 0.57]. No differences in the incidence of ACS [IRR 0.98 (0.87\u20131.11; <jats:italic>P<\/jats:italic> = 0.80)] or TTS [IRR 1.66(0.80\u20133.4), <jats:italic>P<\/jats:italic> = 0.14] were found in the entire period including all matches of the UEFA Euro 2020 compared to the control period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The data of this national registry demonstrated an association between the semifinal and final of UEFA Euro 2020 and TTS suggesting that it can be triggered by also positive emotions such as the victory in the European Football Championship finals.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2022.951882","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T05:37:23Z","timestamp":1664343443000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["The impact of UEFA Euro 2020 football championship on Takotsubo Syndrome: Results of a multicenter national registry"],"prefix":"10.3389","volume":"9","author":[{"given":"Alberto","family":"Polimeni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Spaccarotella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Ielapi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Ravera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenio","family":"Martuscelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Ciconte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Menichelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferdinando","family":"Varbella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Imazio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Navazio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Sinagra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Oberhollenzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerolamo","family":"Sibilio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Cacciavillani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Meloni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Dominici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Tomai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Amico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Corda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Musumeci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Lupi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Zezza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"De Caterina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Cernetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Metra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano","family":"Murrone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Volpe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Caldarola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Carugo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo","family":"Cortese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Valenti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Boriani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Fedele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Ventura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Teresa","family":"Manes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Rita","family":"Colavita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Feola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Versaci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Assennato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Arena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Ceravolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Amodeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Tortorici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Nassiacos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Antonicelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolino","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Favale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Licciardello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Tedesco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciro","family":"Indolfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1056\/NEJMoa0707427","article-title":"Cardiovascular Events during World Cup Soccer","volume":"358","author":"Wilbert-Lampen","year":"2008","journal-title":"N Engl J Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1136\/bmj.325.7378.1439","article-title":"Admissions for myocardial infarction and World Cup football: database survey","volume":"325","author":"Carroll","year":"2002","journal-title":"BMJ."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1093\/ije\/dyq007","article-title":"It is just a game: lack of association between watching football matches and the risk of acute cardiovascular events","volume":"39","author":"Barone-Adesi","year":"2010","journal-title":"Int J Epidemiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.ijcard.2013.10.066","article-title":"Watching soccer is not associated with an increase in cardiac events","volume":"170","author":"Niederseer","year":"2013","journal-title":"Int J Cardiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00392-013-0536-7","article-title":"Takotsubo cardiomyopathy in a male during a Euro 2012 football match","volume":"102","author":"Fijalkowski","year":"2013","journal-title":"Clin Res Cardiol."},{"key":"B6","volume-title":"Statistics in Epidemiology: Methods, Techniques, and Applications","author":"Sahai","year":"1996"},{"key":"B7","first-page":"56","article-title":"Tako-tsubo-like left ventricular dysfunction due to multivessel coronary spasm","volume-title":"Clinical Aspect of Myocardial Injury: From Ischemia to Heart Failure (in Japanese)","author":"Sato","year":"1990"},{"key":"B8","doi-asserted-by":"publisher","first-page":"2754","DOI":"10.1161\/CIRCULATIONAHA.108.767012","article-title":"Takotsubo cardiomyopathy: a new form of acute, reversible heart failure","volume":"118","author":"Akashi","year":"2008","journal-title":"Circulation."},{"key":"B9","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1161\/01.CIR.0000153801.51470.EB","article-title":"Acute and reversible cardiomyopathy provoked by stress in women from the United States","volume":"111","author":"Sharkey","year":"2005","journal-title":"Circulation"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1406761","article-title":"Clinical features and outcomes of takotsubo (stress) cardiomyopathy","author":"Templin","year":"2015","journal-title":"N Engl J Med."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1161\/01.CIR.98.13.1349","article-title":"A broken heart","volume":"98","author":"Brandspiegel","year":"1998","journal-title":"Circulation"},{"key":"B12","doi-asserted-by":"publisher","first-page":"e019583","DOI":"10.1161\/JAHA.120.019583","article-title":"Sex- and age-based temporal trends in Takotsubo syndrome incidence in the United States","volume":"10","author":"Pattisapu","year":"2021","journal-title":"J Am Heart Assoc."},{"key":"B13","article-title":"Pathophysiology of Takotsubo Syndrome\u2014a joint scientific statement from the Heart Failure Association Takotsubo Syndrome Study Group and Myocardial Function Working Group of the European Society of Cardiology - Part 1: Overview and the central role for catecholamines and sympathetic nervous system","author":"Omerovic","year":"2021","journal-title":"Eur J Heart Fail"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e182","DOI":"10.1016\/j.ijcard.2013.12.140","article-title":"\u201cHappiness\u201d and stress cardiomyopathy (apical ballooning syndrome\/takotsubo syndrome)","volume":"172","author":"Qin","year":"2014","journal-title":"Int J Cardiol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/s10286-020-00696-z","article-title":"Happy heart syndrome: a case of Takotsubo syndrome with left internal carotid artery occlusion","volume":"30","author":"Nagai","year":"2020","journal-title":"Clin Auton Res."},{"key":"B16","doi-asserted-by":"publisher","first-page":"228.e1","DOI":"10.1016\/j.cjca.2014.11.011","article-title":"Happiness can break your heart: a rare case of takotsubo cardiomyopathy after good news","volume":"31","author":"Allen","year":"2015","journal-title":"Can J Cardiol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"2823","DOI":"10.1093\/eurheartj\/ehv757","article-title":"Happy heart syndrome: role of positive emotional stress in takotsubo syndrome","volume":"37","author":"Ghadri","year":"2016","journal-title":"Eur Heart J."},{"key":"B18","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.cortex.2021.01.011","article-title":"Effects of insular resection on interactions between cardiac interception and emotion recognition","volume":"137","author":"Terasawa","year":"2021","journal-title":"Cortex."},{"key":"B19","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1126\/science.1071829","article-title":"Serotonin transporter genetic variation and the response of the human amygdala","volume":"297","author":"Hariri","year":"2002","journal-title":"Science."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1136\/bmj.322.7297.1306","article-title":"French cardiovascular mortality did not increase during 1996 European football championship","volume":"322","author":"Toubiana","year":"2001","journal-title":"BMJ."},{"key":"B21","doi-asserted-by":"publisher","first-page":"19","DOI":"10.5837\/bjc.2021.019","article-title":"When Blades broke my heart","volume":"28","author":"Elamin","year":"2021","journal-title":"Br J Cardiol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.1016\/j.amjcard.2015.08.033","article-title":"A missed penalty kick triggered coronary death in the husband and broken heart syndrome in the wife","volume":"116","author":"Y-Hassan","year":"2015","journal-title":"Am J Cardiol"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.951882\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T05:37:29Z","timestamp":1664343449000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2022.951882\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":22,"alternative-id":["10.3389\/fcvm.2022.951882"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2022.951882","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]},"article-number":"951882"}}