{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:51:25Z","timestamp":1753890685431,"version":"3.41.2"},"reference-count":116,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>We present a 55-year-old man with chest tightness and dyspnoea after activity lasting for 2 months who was diagnosed with single coronary artery (SCA) and presented with dilated cardiomyopathy (DCM) with the c.1858C\u2009&amp;gt;\u2009T mutation in the <jats:italic>SCN5A<\/jats:italic> gene. The computed tomography coronary angiogram (CTCA) showed congenital absence of the right coronary artery (RCA), and the right heart was nourished by the left coronary artery branch with no apparent stenosis. Transthoracic echocardiography (TTE) revealed enlargement of the left heart and cardiomyopathy. Cardiac magnetic resonance imaging (CMR) revealed DCM. Genetic testing showed that the c.1858C\u2009&amp;gt;\u2009T variant of the <jats:italic>SCN5A<\/jats:italic> gene could lead to Brugada syndrome and DCM. SCA is a rare congenital anomaly of the coronary anatomy, and this case reported as SCA accompanied by DCM is even rarer. We present a rare case of a 55-year-old man with DCM with the c.1858C\u2009&amp;gt;\u2009T (p. Arg620Cys)\/c.1008G\u2009&amp;gt;\u2009A (p.(Pro336=) variant of the <jats:italic>SCN5A<\/jats:italic> gene, congenital absence of RCA, and c.990_993delAACA (p. Asp332Valfs*5) variant of the <jats:italic>APOA5<\/jats:italic> gene. To our knowledge, this is the first report of DCM combined with the <jats:italic>SCN5A<\/jats:italic> gene mutation in SCA after searching the PubMed, CNKI and Wanfang databases.<\/jats:p>","DOI":"10.3389\/fcvm.2023.1113886","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T04:33:12Z","timestamp":1684816392000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Single coronary artery presenting dilated cardiomyopathy and hyperlipidemia with the SCN5A and APOA5 gene mutation: A case report and review of the literature"],"prefix":"10.3389","volume":"10","author":[{"given":"Xiaoxia","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,5,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1017\/S1047951118000069","article-title":"An extremely rare clinical entity: congenitally corrected transposition with situs Inversus and single coronary artery presented with complete atrioventricular block in a young man","volume":"28","author":"Cirakoglu","year":"2018","journal-title":"Cardiol Young"},{"key":"B2","doi-asserted-by":"publisher","first-page":"469","DOI":"10.5603\/Fm.2014.0070","article-title":"Single coronary artery incidence in 215,140 patients undergoing coronary angiography","volume":"73","author":"Turkmen","year":"2014","journal-title":"Folia Morphol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1136\/heartjnl-2020-316658","article-title":"Considering complexity in the genetic evaluation of dilated cardiomyopathy","volume":"107","author":"Jordan","year":"2021","journal-title":"Heart"},{"key":"B4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s12872-018-0997-8","article-title":"A case of hypertrophic cardiomyopathy combined with muscular ventricular septal defect and abnormal origin of right coronary artery","volume":"19","author":"Zheng","year":"2019","journal-title":"Bmc Cardiovasc Disor"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1093\/eurheartj\/ehv727","article-title":"Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases","volume":"37","author":"Pinto","year":"2016","journal-title":"Eur Heart J"},{"key":"B6","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1093\/eurheartj\/ehm342","article-title":"Classification of the cardiomyopathies: a position statement from the European society of cardiology working group on myocardial and pericardial diseases","volume":"29","author":"Elliott","year":"2008","journal-title":"Eur Heart J"},{"key":"B7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/978-3-030-27371-2_2","article-title":"The genetic landscape of cardiomyopathies","author":"Gerullm","year":"2019","journal-title":"Genet Causes Card Dis"},{"key":"B8","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1111\/joim.12944","article-title":"Dilated cardiomyopathy: from epidemiologic to genetic phenotypes A translational review of current literature","volume":"286","author":"Reichart","year":"2019","journal-title":"J Intern Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1161\/Circresaha.116.309396","article-title":"Dilated cardiomyopathy genetic determinants and mechanisms","volume":"121","author":"McNally","year":"2017","journal-title":"Circ Res"},{"key":"B10","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/ejhg.2014.54","article-title":"Genetic analysis, in silico prediction, and family segregation in long QT syndrome","volume":"23","author":"Riuro","year":"2015","journal-title":"Eur J Hum Genet"},{"key":"B11","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1161\/Circgenetics.114.000831","article-title":"Enhanced classification of brugada syndrome-associated and long-QT syndrome-associated genetic variants in the SCN5A-encoded na(v)1.5 cardiac sodium channel","volume":"8","author":"Kapplinger","year":"2015","journal-title":"Circ-Cardiovasc Gene"},{"key":"B12","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1161\/Circgenetics.113.000292","article-title":"Brugada syndrome disease phenotype explained in apparently benign sodium channel mutations","volume":"7","author":"Hoshi","year":"2014","journal-title":"Circ-Cardiovasc Gene"},{"key":"B13","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.hrthm.2009.09.069","article-title":"An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing","volume":"7","author":"Kapplinger","year":"2010","journal-title":"Heart Rhythm"},{"key":"B14","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.ebiom.2018.11.001","article-title":"Intensive genetic analysis for Chinese patients with very high triglyceride levels: relations of mutations to triglyceride levels and acute pancreatitis","volume":"38","author":"Jin","year":"2018","journal-title":"Ebiomedicine"},{"key":"B15","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1161\/Circulationaha.121.058143","article-title":"Frequency, penetrance, and variable expressivity of dilated cardiomyopathy-associated putative pathogenic gene variants in UK biobank participants","volume":"146","author":"Shah","year":"2022","journal-title":"Circulation"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e024947","DOI":"10.1161\/JAHA.121.024947","article-title":"Sex-related differences in genetic cardiomyopathies","volume":"11","author":"Argiro","year":"2022","journal-title":"J Am Heart Assoc"},{"key":"B17","doi-asserted-by":"publisher","first-page":"101065","DOI":"10.1016\/j.ijcha.2022.101065","article-title":"Incidence rates of dilated cardiomyopathy in adult first-degree relatives versus matched controls","volume":"41","author":"Andersson","year":"2022","journal-title":"Int J Cardiol Heart Vasc"},{"key":"B18","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1136\/heart.87.2.126","article-title":"Epidemiology of idiopathic cardiomyopathy in Japan: results from a nationwide survey","volume":"87","author":"Miura","year":"2002","journal-title":"Heart"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.3389\/fphys.2018.01372","article-title":"SCN5A variants: association with cardiac disorders","volume":"9","author":"Li","year":"2018","journal-title":"Front Physiol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/S0140-6736(16)31713-5","article-title":"Dilated cardiomyopathy","volume":"390","author":"Weintraub","year":"2017","journal-title":"Lancet"},{"key":"B21","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1172\/JCI62862","article-title":"Genetic mutations and mechanisms in dilated cardiomyopathy","volume":"123","author":"McNally","year":"2013","journal-title":"J Clin Invest"},{"key":"B22","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.hrtlng.2011.07.007","article-title":"Novel c.367_369del LMNA mutation manifesting as severe arrhythmias, dilated cardiomyopathy, and myopathy","volume":"41","author":"Keller","year":"2021","journal-title":"Heart Lung"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1002\/humu.24096","article-title":"Cardiomyopathy-associated mutations in the RS domain affect nuclear localization of RBM20","volume":"41","author":"Gaertner","year":"2020","journal-title":"Hum Mutat"},{"key":"B24","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.yjmcc.2015.12.015","article-title":"Functional characterization of the novel DES mutation p.L136P associated with dilated cardiomyopathy reveals a dominant filament assembly defect","volume":"91","author":"Brodehl","year":"2016","journal-title":"J Mol Cell Cardiol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1698","DOI":"10.1161\/CIRCRESAHA.122.319835","article-title":"Arrhythmias as presentation of genetic cardiomyopathy","volume":"130","author":"Lukas Laws","year":"2022","journal-title":"Circ Res"},{"key":"B26","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman","year":"2012","journal-title":"N Engl J Med"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1161\/CIRCULATIONAHA.106.646778","article-title":"Prevalence of desmin mutations in dilated cardiomyopathy","volume":"115","author":"Taylor","year":"2007","journal-title":"Circulation"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1126\/science.1081578","article-title":"Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban","volume":"299","author":"Schmitt","year":"2003","journal-title":"Science"},{"key":"B29","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/ng815","article-title":"Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy","volume":"30","author":"Gerull","year":"2002","journal-title":"Nat Genet"},{"key":"B30","doi-asserted-by":"publisher","first-page":"129","DOI":"10.21037\/atm-21-6774","article-title":"Genetic variants in Chinese patients with sporadic dilated cardiomyopathy: a cross-sectional study","volume":"10","author":"Shen","year":"2022","journal-title":"Ann Transl Med"},{"key":"B31","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.amjcard.2021.04.010","article-title":"Frequency of irritable bowel syndrome in patients with brugada syndrome and drug-induced type 1 brugada pattern","volume":"151","author":"Sarica","year":"2021","journal-title":"Am J Cardiol"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2100066118","article-title":"Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies","volume":"118","author":"Pan","year":"2021","journal-title":"Proc Natl Acad Sci USA"},{"key":"B33","doi-asserted-by":"publisher","first-page":"G494","DOI":"10.1152\/ajpgi.00016.2017","article-title":"Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Na1.5 current and mechanosensitivity","volume":"314","author":"Strege","year":"2018","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"B34","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1111\/nmo.12569","article-title":"The role of the SCN5A-encoded channelopathy in irritable bowel syndrome and other gastrointestinal disorders","volume":"27","author":"Verstraelen","year":"2015","journal-title":"Neurogastroenterol Motil"},{"key":"B35","doi-asserted-by":"publisher","first-page":"G506","DOI":"10.1152\/ajpgi.00051.2015","article-title":"Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells","volume":"309","author":"Neshatian","year":"2015","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"G1111","DOI":"10.1152\/ajpgi.00152.2003","article-title":"Sodium current in human intestinal interstitial cells of Cajal","volume":"285","author":"Strege","year":"2003","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.jaccas.2022.01.016","article-title":"Missense variant E1295K of sodium channel SCN5A associated with recurrent ventricular fibrillation and myocardial inflammation","volume":"4","author":"Poller","year":"2022","journal-title":"JACC Case Rep"},{"key":"B38","doi-asserted-by":"publisher","first-page":"35326","DOI":"10.1074\/jbc.M114.611962","article-title":"Human macrophage SCN5A activates an innate immune signaling pathway for antiviral host defense","volume":"289","author":"Jones","year":"2014","journal-title":"J Biol Chem"},{"key":"B39","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1097\/NEN.0b013e318293eb08","article-title":"Mediation of protection and recovery from experimental autoimmune encephalomyelitis by macrophages expressing the human voltage-gated sodium channel NaV1.5","volume":"72","author":"Rahgozar","year":"2013","journal-title":"J Neuropathol Exp Neurol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.neuron.2013.09.012","article-title":"Noncanonical roles of voltage-gated sodium channels","volume":"80","author":"Black","year":"2013","journal-title":"Neuron"},{"key":"B41","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.jacep.2018.03.006","article-title":"Clinical spectrum of SCN5A mutations: long QT syndrome, brugada syndrome, and cardiomyopathy","volume":"4","author":"Wilde","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"B42","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1161\/CIRCEP.107.750752","article-title":"Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy","volume":"1","author":"Ge","year":"2008","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"944834","DOI":"10.3389\/fcvm.2022.944834","article-title":"Corrigendum: case report: family curse: an SCN5A mutation, c.611C>A, p.A204E associated with a family history of dilated cardiomyopathy and arrhythmia","volume":"9","author":"Huang","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1093\/eurheartj\/ehu301","article-title":"Atlas of the clinical genetics of human dilated cardiomyopathy","volume":"36","author":"Haas","year":"2015","journal-title":"Eur Heart J"},{"key":"B45","doi-asserted-by":"publisher","first-page":"2327","DOI":"10.1093\/eurheartj\/ehv253","article-title":"Genetics and genotype-phenotype correlations in Finnish patients with dilated cardiomyopathy","volume":"36","author":"Akinrinade","year":"2015","journal-title":"Eur Heart J"},{"key":"B46","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1016\/j.jacc.2012.05.050","article-title":"R222q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy","volume":"160","author":"Mann","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"B47","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.jacc.2012.02.052","article-title":"Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy","volume":"60","author":"Laurent","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1161\/CIRCULATIONAHA.110.987248","article-title":"Striking in vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro","volume":"124","author":"Watanabe","year":"2011","journal-title":"Circulation"},{"key":"B49","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.cardiores.2007.04.009","article-title":"Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a","volume":"75","author":"Hesse","year":"2007","journal-title":"Cardiovasc Res"},{"key":"B50","doi-asserted-by":"publisher","first-page":"301","DOI":"10.3389\/fphar.2015.00301","article-title":"Mutations in the voltage sensors of domains I and II of Nav1.5 that are associated with arrhythmias and dilated cardiomyopathy generate gating pore currents","volume":"6","author":"Moreau","year":"2015","journal-title":"Front Pharmacol"},{"key":"B51","doi-asserted-by":"publisher","first-page":"e38331","DOI":"10.1371\/journal.pone.0038331","article-title":"A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype","volume":"7","author":"Gosselin-Badaroudine","year":"2012","journal-title":"PLoS One"},{"key":"B52","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1161\/CIRCRESAHA.107.164673","article-title":"Divergent biophysical defects caused by mutant sodium channels in dilated cardiomyopathy with arrhythmia","volume":"102","author":"Nguyen","year":"2008","journal-title":"Circ Res"},{"key":"B53","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1161\/CIRCRESAHA.110.228312","article-title":"SAP97 And dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes","volume":"108","author":"Petitprez","year":"2011","journal-title":"Circ Res"},{"key":"B54","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1097\/HCO.0000000000000845","article-title":"Genetics of dilated cardiomyopathy","volume":"39","author":"K\u00e4rkk\u00e4inen","year":"2007","journal-title":"Ann Med"},{"key":"B55","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1161\/01.RES.0000237466.13252.5e","article-title":"Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin","volume":"99","author":"Gavillet","year":"2006","journal-title":"Circ Res"},{"key":"B56","doi-asserted-by":"publisher","first-page":"2769","DOI":"10.1161\/CIRCULATIONAHA.105.532614","article-title":"Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study","volume":"112","author":"Coronel","year":"2005","journal-title":"Circulation"},{"key":"B57","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/415227a","article-title":"The failing heart","volume":"415","author":"Towbin","year":"2002","journal-title":"Nature"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1016\/j.hrthm.2014.04.042","article-title":"Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy","volume":"11","author":"Beckermann","year":"2014","journal-title":"Heart Rhythm"},{"key":"B59","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1016\/j.hrthm.2014.05.031","article-title":"SCN5A-related Dilated cardiomyopathy: what do we know?","volume":"11","author":"Amin","year":"2014","journal-title":"Heart Rhythm"},{"key":"B60","first-page":"195","article-title":"Extremely rare single right coronary artery: multidetector computed tomography findings","volume":"82","author":"Echavarria-Pinto","year":"2012","journal-title":"Arch Cardiol Mex"},{"key":"B61","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1002\/clc.4960281009","article-title":"Anomalous coronary arteries: a familial clustering","volume":"28","author":"Laureti","year":"2005","journal-title":"Clin Cardiol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1097\/00000441-193809000-00015","article-title":"Varieties of single coronary artery in man, occurring as isolated cardiac anomalies","volume":"196","author":"Krumbhaar","year":"1938","journal-title":"Am J Med Sci"},{"key":"B63","doi-asserted-by":"publisher","first-page":"565","DOI":"10.4070\/kcj.2012.42.8.565","article-title":"Right ventricular myocardial infarction due to right coronary artery total occlusion originating from the distal left circumflex artery","volume":"42","author":"Ma","year":"2012","journal-title":"Korean Circ J"},{"key":"B64","first-page":"150","article-title":"Anomalous origin of coronary arteries from a single sinus of Valsalva","volume":"17","author":"Chen","year":"2012","journal-title":"Exp Clin Cardiol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"325","DOI":"10.5543\/tkda.2011.00769","article-title":"Right coronary artery arising from the distal left circumflex artery","volume":"39","author":"Sonmez","year":"2011","journal-title":"Turk Kardiyol Dern Ars"},{"key":"B66","doi-asserted-by":"publisher","first-page":"130","DOI":"10.4103\/0975-3583.83038","article-title":"Single dominant left coronary artery: an autopsy case report with review of literature","volume":"2","author":"Kalyani","year":"2011","journal-title":"J Cardiovasc Dis Res"},{"key":"B67","first-page":"E172","article-title":"An unusual cause of right ventricular myocardial infarction","volume":"22","author":"Voyce","year":"2010","journal-title":"J Invasive Cardiol"},{"key":"B68","first-page":"844","article-title":"Pulmonary embolism in a patient with a rare coronary anomaly\u2014a clue to the importance of proximal right coronary artery branches","volume":"68","author":"Ghaffari","year":"2010","journal-title":"Kardiol Pol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/s0828-282x(10)70404-9","article-title":"Anomalous right coronary artery originating from the distal left circumflex artery: a novel coronary artery anomaly viewed by computed tomography and invasive angiography","volume":"26","author":"Datta","year":"2010","journal-title":"Can J Cardiol"},{"key":"B70","doi-asserted-by":"publisher","first-page":"465","DOI":"10.4070\/kcj.2010.40.9.465","article-title":"An extremely rare variety of anomalous coronary artery: right coronary artery originating from the distal left circumflex artery","volume":"40","author":"Chung","year":"2010","journal-title":"Korean Circ J"},{"key":"B71","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.jjcc.2009.03.014","article-title":"Unusual dominant course of left circumflex coronary artery to right coronary artery territory with absent right coronary artery","volume":"55","author":"Choi","year":"2010","journal-title":"J Cardiol"},{"key":"B72","first-page":"362","article-title":"Anomalous single coronary artery with absent right coronary artery diagnosed with the aid of 64-slice multidetector computed tomographic angiography","volume":"36","author":"Tanawuttiwat","year":"2009","journal-title":"Tex Heart Inst J"},{"key":"B73","first-page":"459","article-title":"Anomalous right coronary artery arising from the distal left circumflex coronary artery","volume":"8","author":"Celik","year":"2008","journal-title":"Anadolu Kardiyol Derg"},{"key":"B74","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.ijcard.2006.01.039","article-title":"Absence of the right coronary artery detected by 64-detector-row multislice computed tomography","volume":"115","author":"Kunimasa","year":"2007","journal-title":"Int J Cardiol"},{"key":"B75","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1136\/hrt.2005.073668","article-title":"Images in cardiology. Unusual dominant course of left circumflex coronary artery with absent right coronary artery","volume":"92","author":"Kang","year":"2006","journal-title":"Heart"},{"key":"B76","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.ijcard.2004.03.075","article-title":"Anomalous left anterior descending, absent circumflex and unusual dominant course of right coronary artery: a case report--R1","volume":"102","author":"Vijayvergiya","year":"2005","journal-title":"Int J Cardiol"},{"key":"B77","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1536\/jhj.45.679","article-title":"Anomalous right coronary artery originating from the distal left circumflex artery: single coronary artery with chronic atrial fibrillation","volume":"45","author":"Yoshimoto","year":"2004","journal-title":"Jpn Heart J"},{"key":"B78","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1536\/jhj.45.337","article-title":"Right coronary artery originating from distal left circumflex artery in a patient with an unusual type of isolated single coronary artery","volume":"45","author":"Chou","year":"2004","journal-title":"Jpn Heart J"},{"key":"B79","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/s0167-5273(02)00324-8","article-title":"Right coronary artery originating from distal left circumflex: an extremely rare variety of single coronary artery","volume":"88","author":"Turhan","year":"2003","journal-title":"Int J Cardiol"},{"key":"B80","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1177\/021849230301100217","article-title":"Single coronary artery from the left sinus with atherosclerosis","volume":"11","author":"Asha","year":"2003","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"B81","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1002\/clc.4960240115","article-title":"Single left coronary artery with origin of the right coronary artery from distal circumflex","volume":"24","author":"Shammas","year":"2001","journal-title":"Clin Cardiol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"1637","DOI":"10.1093\/oxfordjournals.eurheartj.a060117","article-title":"Isolated single coronary artery: a review of 50,000 consecutive coronary angiographies","volume":"13","author":"Desmet","year":"1992","journal-title":"Eur Heart J"},{"key":"B83","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1093\/eurheartj\/12.6.746","article-title":"Right coronary artery originating from distal left circumflex: an unusual feature of single coronary artery","volume":"12","author":"Vrolix","year":"1991","journal-title":"Eur Heart J"},{"key":"B84","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/ccd.1810140310","article-title":"Single coronary artery: right coronary artery originating from distal left circumflex","volume":"14","author":"Sheth","year":"1988","journal-title":"Cathet Cardiovasc Diagn"},{"key":"B85","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1002\/clc.4960090514","article-title":"Anomalous origin of the right coronary artery arising from the circumflex artery","volume":"9","author":"Tavernarakis","year":"1986","journal-title":"Clin Cardiol"},{"key":"B86","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1148\/130.1.39","article-title":"Isolated single coronary artery: diagnosis, angiographic classification, and clinical significance","volume":"130","author":"Lipton","year":"1979","journal-title":"Radiology"},{"key":"B87","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/0002-8703(64)90404-1","article-title":"Single coronary artery: a report of two cases","volume":"67","author":"Laurie","year":"1964","journal-title":"Am Heart J"},{"key":"B88","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1161\/01.cir.1.5.1168","article-title":"Review of single coronary artery with report of 2 cases","volume":"1","author":"Smith","year":"1950","journal-title":"Circulation"},{"key":"B89","first-page":"E147","article-title":"Coronary stenting in a patient with single coronary artery and double-vessel disease!","volume":"25","author":"Devidutta","year":"2013","journal-title":"J Invasive Cardiol"},{"key":"B90","first-page":"161","article-title":"Single coronary artery with anomalous origin of the right coronary artery from the distal portion of left circumflex artery: a very rare case","volume":"8","author":"Pourbehi","year":"2013","journal-title":"J Tehran Heart Cent"},{"key":"B91","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1093\/eurheartj\/ehu497","article-title":"Rare case of isolated single coronary artery causing ischaemia","volume":"36","author":"Inaba","year":"2015","journal-title":"Eur Heart J"},{"key":"B92","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.ijcard.2015.03.084","article-title":"Guideliner use for the percutaneous treatment of right coronary artery arising from the left circumflex (L-type single coronary artery)","volume":"185","author":"Garcia-Blas","year":"2015","journal-title":"Int J Cardiol"},{"key":"B93","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1016\/j.ijcard.2014.04.145","article-title":"Single left coronary artery with the right coronary artery arising as a continuation from the distal circumflex coronary artery assessed by multislice computed tomography","volume":"174","author":"de Agustin","year":"2014","journal-title":"Int J Cardiol"},{"key":"B94","doi-asserted-by":"publisher","first-page":"OD03-4","DOI":"10.7860\/JCDR\/2016\/20629.8266","article-title":"Percutaneous coronary intervention of hidden coronary artery-unusual type of isolated single coronary artery","volume":"10","author":"Patil","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"B95","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4103\/1995-705X.164465","article-title":"Angiographic enigma: a single coronary artery with the right coronary artery originating from the distal left circumflex artery","volume":"16","author":"Singh","year":"2015","journal-title":"Heart Views"},{"key":"B96","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.ijcard.2015.03.032","article-title":"Left main coronary artery and ostial left anterior descending coronary artery stenting in a single coronary artery during NSTEMI. The OCT response","volume":"184","author":"Buccheri","year":"2015","journal-title":"Int J Cardiol"},{"key":"B97","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.jccase.2014.07.011","article-title":"Successful percutaneous intervention of proximal left anterior descending artery in a case of single coronary artery trunk","volume":"10","author":"Zamani","year":"2014","journal-title":"J Cardiol Cases"},{"key":"B98","doi-asserted-by":"publisher","first-page":"127","DOI":"10.5681\/jcvtr.2014.027","article-title":"Anomalous origin of right coronary artery from distal left circumflex artery: a case study and a review of its clinical significance","volume":"6","author":"Pourafkari","year":"2014","journal-title":"J Cardiovasc Thorac Res"},{"key":"B99","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.ihj.2014.03.011","article-title":"Percutaneous coronary intervention in a patient with single coronary artery","volume":"66","author":"Mishra","year":"2014","journal-title":"Indian Heart J"},{"key":"B100","doi-asserted-by":"publisher","first-page":"822","DOI":"10.3904\/kjim.2014.29.6.822","article-title":"Funtional significance of the intermediate lesion in a single coronary artery assessed by fractional flow reserve","volume":"29","author":"Ha","year":"2014","journal-title":"Korean J Intern Med"},{"key":"B101","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1007\/s10554-014-0458-0","article-title":"Successful aortic root replacement and shunt closure in a case with rare coexistence of congenital cardiac malformations: bicuspid aortic valve with annuloaortic ectasia, single coronary artery, and patent foramen ovale","volume":"30","author":"Egashira","year":"2014","journal-title":"Int J Cardiovasc Imaging"},{"key":"B102","first-page":"375","article-title":"Percutaneous intervention in a patient with a rare single coronary artery from the left coronary sinus of valsava","volume":"19","author":"Dai","year":"2014","journal-title":"J Res Med Sci"},{"key":"B103","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1177\/0218492313475641","article-title":"Single coronary artery anomaly causing ischemic mitral insufficiency","volume":"22","author":"Ay","year":"2014","journal-title":"Asian Cardiovasc Thorac Ann"},{"key":"B104","first-page":"E216","article-title":"An isolated single L-I type coronary artery with severe LAD lesions treated by transradial PCI","volume":"23","author":"Kafkas","year":"2011","journal-title":"J Invasive Cardiol"},{"key":"B105","doi-asserted-by":"publisher","first-page":"e931535","DOI":"10.12659\/AJCR.931535","article-title":"A 59-year-old woman with familial brugada syndrome and the c.664C>T variant of the sodium voltage-gated channel alpha subunit 5 (SCN5A) gene, accompanied by congenital absence of the right coronary artery, patent foramen Ovale, and ischemic stroke","volume":"22","author":"Katsaras","year":"2021","journal-title":"Am J Case Rep"},{"key":"B106","doi-asserted-by":"publisher","first-page":"e932248","DOI":"10.12659\/AJCR.932248","article-title":"A rare anatomical variant: congenital absence of the right coronary artery with left circumflex artery supplying the right coronary artery (RCA) territory","volume":"22","author":"Ahmed","year":"2021","journal-title":"Am J Case Rep"},{"key":"B107","doi-asserted-by":"publisher","first-page":"379","DOI":"10.2147\/IMCRJ.S232401","article-title":"St elevation myocardial infarction in a patient with an anomalous right coronary artery originating from the distal left circumflex","volume":"12","author":"Phan","year":"2019","journal-title":"Int Med Case Rep J"},{"key":"B108","doi-asserted-by":"publisher","first-page":"S80","DOI":"10.29271\/jcpsp.2019.12.S80","article-title":"A single coronary artery with an absent right coronary and a superdominant left circumflex giving off a branch supplying the right coronary artery territory","volume":"29","author":"Iftikhar","year":"2019","journal-title":"J Coll Physicians Surg Pak"},{"key":"B109","first-page":"E244","article-title":"A rare case of a congenital single coronary artery: right coronary artery originating from the distal left circumflex artery","volume":"10","author":"Blaschke","year":"2013","journal-title":"Vasc Dis Manag"},{"key":"B110","doi-asserted-by":"publisher","first-page":"983","DOI":"10.2459\/JCM.0000000000000582","article-title":"Single coronary artery anomaly and chest pain","volume":"18","author":"Gatti","year":"2017","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"B111","doi-asserted-by":"publisher","first-page":"111","DOI":"10.31083\/j.rcm.2018.03.3184","article-title":"Characterizing an absent right coronary artery through 3-dimensional coronary computed tomography angiography","volume":"19","author":"Lee","year":"2018","journal-title":"Rev Cardiovasc Med"},{"key":"B112","first-page":"E45","article-title":"Superdominant circumflex thrombosis with occluded LAD and absent RCA ostium","volume":"31","author":"da Silva Matte","year":"2019","journal-title":"J Invasive Cardiol"},{"key":"B113","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/0735-1097(89)90588-3","article-title":"Anomalous coronary arteries: location, degree of atherosclerosis and effect on survival--a report from the coronary artery surgery study","volume":"13","author":"Click","year":"1989","journal-title":"J Am Coll Cardiol"},{"key":"B114","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/s0828-282x(07)70820-6","article-title":"Right coronary artery arising as a terminal extension of the circumflex artery (a rare coronary artery anomaly)","volume":"23","author":"Tanriverdi","year":"2007","journal-title":"Can J Cardiol"},{"key":"B115","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1007\/s00508-010-1420-3","article-title":"Percutaneous coronary intervention of an anomalous right coronary artery originating from the left coronary artery","volume":"122","author":"Rudan","year":"2010","journal-title":"Wien Klin Wochenschr"},{"key":"B116","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/0735-1097(93)90728-j","article-title":"Solitary coronary ostium in the aorta in the absence of other major congenital cardiovascular anomalies","volume":"21","author":"Shirani","year":"1993","journal-title":"J Am Coll Cardiol"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2023.1113886\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T04:33:27Z","timestamp":1684816407000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2023.1113886\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,22]]},"references-count":116,"alternative-id":["10.3389\/fcvm.2023.1113886"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2023.1113886","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2023,5,22]]},"article-number":"1113886"}}