{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:42:48Z","timestamp":1778791368671,"version":"3.51.4"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Giant coronary artery aneurysm (CAA) is a relatively uncommon disease that is defined by a focal dilation of at least 20\u2005mm and characterized by various clinical symptoms. However, cases presenting primarily with hemoptysis have not been reported. A man in his late 20\u2005s suffering from persistent chest pain for over 2 months was transferred to our emergency department for intermittent hemoptysis lasting for 12\u2005h. Bronchoscopy detected fresh blood in the left upper lobe bronchus without a definite bleeding source. Magnetic resonance imaging (MRI) demonstrated a heterogeneous mass and the high-intensity signals suggested active bleeding. coronary computed tomography (CT) angiography demonstrated a giant ruptured CAA wrapped in a large mediastinal mass Coronary angiography confirmed the CAA originating from the left anterior descending artery. The patient underwent an emergency sternotomy and an enormous hematoma arising from a ruptured CAA densely adhering to the left lung was identified. The patient recovered uneventfully and was discharged on the 7th day later. The ruptured CAA masquerading as hemoptysis highlights the indispensability of multimodality imaging for accurate diagnosis. Urgent surgical intervention is desirable in such life-threatening conditions.<\/jats:p>","DOI":"10.3389\/fcvm.2023.1185089","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T04:53:06Z","timestamp":1684903986000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case report: Multimodality imaging revealing ruptured giant coronary artery aneurysm presenting with hemoptysis"],"prefix":"10.3389","volume":"10","author":[{"given":"Xiangfeng","family":"Gong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongwei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanlin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenghua","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.chest.2019.07.012","article-title":"Managing massive hemoptysis","volume":"157","author":"Davidson","year":"2020","journal-title":"Chest"},{"key":"B2","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1055\/s-0040-1714386","article-title":"Life-threatening hemoptysis","volume":"42","author":"Deshwal","year":"2021","journal-title":"Semin Respir Crit Care Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"e003289","DOI":"10.1161\/JAHA.116","article-title":"Coronary artery aneurysms in Kawasaki disease: risk factors for progressive disease and adverse cardiac events in the US population","volume":"5","author":"Friedman","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"B4","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4330\/wjc.v13.i9.446","article-title":"Coronary artery aneurysm: a review","volume":"13","author":"Matta","year":"2021","journal-title":"World J Cardiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e009516","DOI":"10.1161\/CIRCIMAGING.119.009516","article-title":"Rupture of a coronary artery aneurysm and fistula to the pulmonary artery","volume":"12","author":"Yeung","year":"2019","journal-title":"Circ Cardiovasc Imaging"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/j.jcin.2018.02.041","article-title":"Management of coronary artery aneurysms","volume":"11","author":"Kawsara","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"B7","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.acvd.2019.10.008","article-title":"Giant coronary aneurysms, from diagnosis to treatment: a literature review","volume":"113","author":"Pham","year":"2020","journal-title":"Arch Cardiovasc Dis"},{"key":"B8","doi-asserted-by":"publisher","first-page":"642","DOI":"10.2459\/01.JCM.0000281695.31112.90","article-title":"Coronary-to-bronchial anastomosis: an unusual cause of hemoptysis","volume":"8","author":"Lorusso","year":"2007","journal-title":"J Cardiovasc Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s40560-020-00441-8","article-title":"Management of life-threatening hemoptysis","volume":"8","author":"Kathuria","year":"2020","journal-title":"J Intensive Care"},{"key":"B10","doi-asserted-by":"publisher","first-page":"873421","DOI":"10.3389\/fped.2022.873421","article-title":"Practical workflow for cardiovascular assessment and follow-up in Kawasaki disease based on expert opinion","volume":"10","author":"van Stijn","year":"2022","journal-title":"Front Pediatr"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.148\/rg.297095048","article-title":"Coronary artery aneurysms and ectasia: role of coronary CT angiography","volume":"29","author":"D\u00edaz-Zamudio","year":"2009","journal-title":"Radiographics"},{"key":"B12","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/s12098-013-1229-y","article-title":"Kawasaki disease and the emerging coronary artery disease epidemic in India: is there a correlation?","volume":"81","author":"Singh","year":"2014","journal-title":"Indian J Pediatr"},{"key":"B13","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3389\/fcvm.2017.00024","article-title":"Coronary artery aneurysms: a review of the epidemiology, pathophysiology, diagnosis, and treatment","volume":"4","author":"Abou Sherif","year":"2017","journal-title":"Front Cardiovasc Med"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1738","DOI":"10.016\/j.jacc.2015.12.073","article-title":"Kawasaki disease","volume":"67","author":"Newburger","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.cell.2020.09.016","article-title":"The immunology of multisystem inflammatory syndrome in children with COVID-19","volume":"183","author":"Consiglio","year":"2020","journal-title":"Cell"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.038\/s41591-020-01163-y","article-title":"COVID-19-induced Kawasaki disease","volume":"26","author":"Carvalho","year":"2020","journal-title":"Nat Med"},{"key":"B17","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1136\/hrt.78.2.136","article-title":"The natural history of aneurysmal coronary artery disease","volume":"78","author":"Demopoulos","year":"1997","journal-title":"Heart"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.4244\/EIJV12I10A210","article-title":"Coronary covered stents","volume":"12","author":"Kilic","year":"2016","journal-title":"EuroIntervention"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.93\/ehjci\/jes131","article-title":"Giant pseudoaneurysm of a saphenous vein graft","volume":"13","author":"del Castillo Carnevali","year":"2012","journal-title":"Eur Heart J Cardiovasc Imaging"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2023.1185089\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T04:53:09Z","timestamp":1684903989000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2023.1185089\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,24]]},"references-count":19,"alternative-id":["10.3389\/fcvm.2023.1185089"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2023.1185089","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,24]]},"article-number":"1185089"}}