{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:50:01Z","timestamp":1753890601458,"version":"3.41.2"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Recently it has been proposed a new approach to estimate aortic systolic blood pressure (aoSBP) without the need for specific devices, operator-dependent techniques and\/or complex wave propagation models\/algorithms. The approach proposes aoSBP can be quantified from brachial diastolic and mean blood pressure (bDBP, bMBP) as: aoSBP\u2009=\u2009bMBP<jats:sup>2<\/jats:sup>\/bDBP. It remains to be assessed to what extent the method and\/or equation used to obtain the bMBP levels considered in aoSBP calculation may affect the estimated aoSBP, and consequently the agreement with aoSBP invasively recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Brachial and aortic pressure were simultaneously obtained invasively (catheterization) and non-invasively (brachial oscillometry) in 89 subjects. aoSBP was quantified in seven different ways, using measured (oscillometry-derived) and calculated (six equations) mean blood pressure (MBP) levels. The agreement between invasive and estimated aoSBP was analyzed (Concordance correlation coefficient; Bland-Altman Test).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ability of the equation \u201caoSBP\u2009=\u2009MBP<jats:sup>2<\/jats:sup>\/DBP\u201d to (accurately) estimate (error &amp;lt;5\u2005mmHg) invasive aoSBP depends on the method and equation considered to determine bMBP, and on the aoSBP levels (proportional error). Oscillometric bMBP and\/or approaches that consider adjustments for heart rate or a form factor \u223c40% (instead of the usual 33%) would be the best way to obtain the bMBP levels to be used to calculate aoSBP.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2023.1207069","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T11:26:23Z","timestamp":1690284383000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Direct estimation of central aortic pressure from measured or quantified mean and diastolic brachial blood pressure: agreement with invasive 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