{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:03:39Z","timestamp":1791403419043,"version":"4.3.3"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The extent of surgery and the role of the frozen elephant trunk (FET) for surgical repair of acute aortic dissection type I are still subjects of debate. The aim of the study is to evaluate the short- and long-term results of acute surgical repair of aortic dissection type I using the FET compared to standard proximal aortic repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between October 2009 and December 2016, 172 patients underwent emergent surgery for acute type I aortic dissection at our center. Of these, <jats:italic>n<\/jats:italic>\u2009=\u200972 received a FET procedure, while the other 100 patients received a conventional proximal aortic repair. Results were compared between the two surgery groups. The primary endpoints included 30-day rates of mortality and neurologic deficit and follow-up rates of mortality and aortic-related reintervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Demographic data were comparable between the groups, except for a higher proportion of men in the FET group (76.4% vs. 60.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.03). The median age was 62 years [IQR (20), <jats:italic>p<\/jats:italic>\u2009=\u20090.17], and the median log EuroSCORE was 38.6% [IQR (31.4), <jats:italic>p<\/jats:italic>\u2009=\u20090.21]. The mean follow-up time was 68.3\u2009\u00b1\u200933.8 months. Neither early (FET group 15.3% vs. proximal group 23.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.25) nor late (FET group 26.2% vs. proximal group 23.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.69) mortality showed significant differences between the groups. There were fewer strokes in the FET patients (FET group 2.8% vs. proximal group 11.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.04), and the rates of spinal cord injury were similar between the groups (FET group 4.2% vs. proximal group 2.0%, <jats:italic>p<\/jats:italic>\u2009=\u20090.41). Aortic-related reintervention rates did not differ between the groups (FET group 12.1% vs. proximal group 9.8%, <jats:italic>p<\/jats:italic>\u2009=\u20090.77).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Emergent FET repair for acute aortic dissection type I is safe and feasible when performed by experienced surgeons. The benefits of the FET procedure in the long term remain unclear. Prolonged follow-up data are needed.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2024.1326124","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T04:44:41Z","timestamp":1710477881000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Frozen elephant trunk versus conventional proximal repair of acute aortic dissection type I"],"prefix":"10.3389","volume":"11","author":[{"given":"Nora","family":"G\u00f6bel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Holder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"H\u00fcther","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Anguelov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothee","family":"Bail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Franke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1093\/ejcts\/ezv085","article-title":"Current status and recommendations for use of the frozen elephant trunk technique: a position paper by the vascular domain of EACTS","volume":"47","author":"Shrestha","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","article-title":"2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. 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