{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T15:31:22Z","timestamp":1778945482674,"version":"3.51.4"},"reference-count":6,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Cholesterol granuloma is a rare entity, which can develop in many regions of the body, accounting at most 1% of all mediastinal tumors. Etiology of this granuloma is still not clearly understood. The gold standard choice of treatment for cholesterol granuloma is total surgical resection. Symptomatic mediastinum granuloma can be easily diagnosed, but if mass effect is not evident then diagnosis of this tumor is really challenging. We present a rare case of huge cholesterol granuloma in the anterior mediastinum of the patient who underwent on elective coronary artery graft bypass surgery.<\/jats:p>","DOI":"10.3389\/fcvm.2024.1359731","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T04:58:06Z","timestamp":1714107486000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Giant cholesterol granuloma in the anterior mediastinum"],"prefix":"10.3389","volume":"11","author":[{"given":"Milica","family":"Ludoski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Zivkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petar","family":"Milacic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Novica","family":"Boricic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodan","family":"Micovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milovan","family":"Bojic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran","family":"Tabakovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,4,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1186\/s40792-020-00943-5","article-title":"Multifocal cholesterol granulomas of the anterior mediastinum","volume":"6","author":"Manabe","year":"2020","journal-title":"Surg Case Rep"},{"key":"B2","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.hlc.2012.07.009","article-title":"A rare case of cholesterol granuloma in the anterior mediastinum","volume":"22","author":"Krishnan","year":"2013","journal-title":"Heart Lung Circ"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1097\/JTO.0b013e318158eee8","article-title":"Focal cholesterol granuloma in the anterior mediastinum: [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography and magnetic resonance imaging findings","volume":"2","author":"Fujimoto","year":"2007","journal-title":"J Thorac Oncol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1136\/thoraxjnl-2016-209481","article-title":"Cholesterol granuloma of the anterior mediastinum","volume":"72","author":"Drury","year":"","journal-title":"Thorax"},{"key":"B5","doi-asserted-by":"publisher","first-page":"108852","DOI":"10.1016\/j.ijscr.2023.108852","article-title":"Cholesterol granuloma of the anterior mediastinum: a case report and literature review","volume":"111","author":"Hongo","year":"2023","journal-title":"Int J Surg Case Rep"},{"key":"B6","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1007\/s00428-015-1822-8","article-title":"Primary thymic cholesteroloma: a clinicopathological correlation of four cases of an unusual benign lesion","volume":"467","author":"Weissferdt","year":"2015","journal-title":"Virchows Arch"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2024.1359731\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T04:58:09Z","timestamp":1714107489000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2024.1359731\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,26]]},"references-count":6,"alternative-id":["10.3389\/fcvm.2024.1359731"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2024.1359731","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,26]]},"article-number":"1359731"}}