{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:49:58Z","timestamp":1762177798161,"version":"3.41.2"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The most reliable care quality indicators for STEMI patients undergoing primary percutaneous coronary intervention (pPCI) include onset-to-door time (OTDT), time from admission to wire crossing and in-hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>Our study aimed to evaluate the impact of the COVID-19 pandemic on these selected care quality indicators in pre-pandemic and pandemic groups of STEMI patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This single-centre, retrospective study, enrolled 480 STEMI patients, aged 63.59\u2009\u00b1\u200912.44 years treated with pPCI across two time frames: pre-pandemic (<jats:italic>n<\/jats:italic>\u2009=\u2009331) and pandemic (<jats:italic>n<\/jats:italic>\u2009=\u2009149). The evaluation criteria included OTDT, time from admission to PCI-mediated reperfusion, in-hospital mortality, and predictors of time delays.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study revealed a significant increases in OTDT (median 3\u2005h; IQR 1.5\u201312.0 vs. median 5\u2005h; IQR 2.0\u201324.0, <jats:italic>p<\/jats:italic>\u2009=\u20090.011) and time from admission to wire crossing (median 92\u2005min; IQR 65.0\u2013187.0 vs. median 115.0; IQR 73.0\u2013233.0, <jats:italic>p<\/jats:italic>\u2009=\u20090.025), in the COVID-19 pandemic group of STEMI patients, compared to the pre-pandemic subset. We also observed an increase in in-hospital mortality (7.85% vs. 14.09%, <jats:italic>p<\/jats:italic>\u2009=\u20090.033) and incidence of cardiogenic shock\/cardiac arrest (16.62% vs. 26.85%, <jats:italic>p<\/jats:italic>\u2009=\u20090.009). Additionally, the proportion of patients with prolonged OTDT (24.45% vs. 35.71%, <jats:italic>p<\/jats:italic>\u2009=\u20090.019) and extended time from admission to PCI-mediated reperfusion (51.96% vs. 65.77%, <jats:italic>p<\/jats:italic>\u2009=\u20090.005) increased during the pandemic period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study's results indicated prolonged OTDT and admission-to-wire crossing times, increased in-hospital mortality, and the higher frequency of cardiogenic shock\/cardiac arrest during the COVID-19 pandemic. These findings demonstrate the negative impact of the pandemic on treatment times and outcomes for patients diagnosed with STEMI.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2025.1522661","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T05:25:38Z","timestamp":1744781138000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["The impact of the COVID-19 pandemic on ST-segment elevation myocardial infarction treatment strategy and outcomes"],"prefix":"10.3389","volume":"12","author":[{"given":"Jakub","family":"Bychowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Michalski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Sobiczewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi\u0142osz","family":"Jaguszewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Grucha\u0142a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"m1036","DOI":"10.1136\/bmj.m1036","article-title":"COVID-19: WHO declares pandemic because of \u201calarming levels\u201d of spread, severity, and inaction","volume":"368","author":"Mahase","year":"2020","journal-title":"Br Med J"},{"key":"B2","doi-asserted-by":"publisher","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes: developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC)","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"E568","DOI":"10.1002\/ccd.29134","article-title":"Clinical and procedural characteristics of COVID-19 patients treated with percutaneous coronary interventions","volume":"96","author":"Siudak","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"key":"B4","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1093\/eurheartj\/ehaa409","article-title":"Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era","volume":"41","author":"De Rosa","year":"2020","journal-title":"Eur Heart J"},{"key":"B5","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1016\/j.jacc.2020.09.546","article-title":"Impact of COVID-19 pandemic on mechanical reperfusion for patients with STEMI","volume":"76","author":"De Luca","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1093\/eurheartj\/ehaa381","article-title":"EAPCI position statement on invasive management of acute coronary syndromes during the COVID-19 pandemic","volume":"41","author":"Chieffo","year":"2020","journal-title":"Eur Heart J"},{"key":"B7","doi-asserted-by":"publisher","first-page":"16695","DOI":"10.20452\/pamw.16695","article-title":"Treatment delays and in-hospital outcomes of patients with ST-segment elevation myocardial infarction treated at a tertiary center in Poland","volume":"134","author":"Bychowski","year":"2024","journal-title":"Pol Arch Intern Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1002\/ehf2.13075","article-title":"Increased mortality and worse cardiac outcome of acute myocardial infarction during the early COVID-19 pandemic","volume":"8","author":"Primessnig","year":"2021","journal-title":"ESC Heart Fail"},{"key":"B9","doi-asserted-by":"publisher","first-page":"386","DOI":"10.14740\/cr1175","article-title":"Delays in presentation in patients with acute myocardial infarction during the COVID-19 pandemic","volume":"11","author":"Aldujeli","year":"2020","journal-title":"Cardiol Res"},{"key":"B10","doi-asserted-by":"publisher","first-page":"3693","DOI":"10.2169\/internalmedicine.8220-21","article-title":"Impact of the COVID-19 pandemic on ST-elevation myocardial infarction from a single-center experience in Tokyo","volume":"60","author":"Watanabe","year":"2021","journal-title":"Intern Med"},{"key":"B11","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1080\/10903127.2020.1817212","article-title":"Strategies to handle increased demand in the COVID-19 crisis: a coronavirus EMS support track and a web-based self-triage system","volume":"25","author":"Jensen","year":"2021","journal-title":"Prehosp Emerg Care"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.14005","article-title":"Effect of COVID-19 pandemic process on STEMI patients timeline","volume":"75","author":"Soylu","year":"2021","journal-title":"Int J Clin Pract"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1093\/eurheartj\/eht529","article-title":"Reperfusion therapy for ST elevation acute myocardial infarction 2010\/2011: current status in 37 ESC countries","volume":"35","author":"Kristensen","year":"2014","journal-title":"Eur Heart J"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.jacc.2020.06.039","article-title":"Management and outcomes of patients with STEMI during the COVID-19 pandemic in China","volume":"76","author":"Xiang","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1136\/heartjnl-2020-318360","article-title":"Effect of the COVID-19 pandemic on mortality of patients with STEMI: a systematic review and meta-analysis","volume":"107","author":"Rattka","year":"2021","journal-title":"Heart"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1522661\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T05:25:38Z","timestamp":1744781138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1522661\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,16]]},"references-count":15,"alternative-id":["10.3389\/fcvm.2025.1522661"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2025.1522661","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2025,4,16]]},"article-number":"1522661"}}