{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T10:13:55Z","timestamp":1776593635477,"version":"3.51.2"},"reference-count":69,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Secundum Atrial septal defect (ASD) is the most common type of ASD. When it is large and hemodynamically significant, it can cause symptoms such as dyspnea, exercise intolerance, and palpitations. Following diagnosis confirmation, an ASD with hemodynamic significance should be closed electively. Percutaneous closure (PC) is an effective treatment option for ostium secundum ASD with adequate rims, despite the potential for several complications. This is the first study in Ethiopia and sub-Saharan Africa to report on percutaneous closure of secundum atrial septal defects (ASD) in children, adolescents, and adults. The study assessed the clinical characteristics, immediate and in-hospital outcomes, and complication rates following PC of secundum ASD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>his follow-up study, conducted between October 2023 and January 2024, involved 99 patients who underwent percutaneous closure (PC) of ASD at the Cardiac Center of Ethiopia between January 2013 and January 2023. The patients were divided into two groups based on age: Group 1 included children and adolescents (\u226418 years of age; <jats:italic>n<\/jats:italic>\u2009=\u200942), while Group 2 consisted of adults (&amp;gt;18 years of age; <jats:italic>n<\/jats:italic>\u2009=\u200957), at the time of device percutaneous closure. The median and interquartile range was used to describe continuous variables. The absolute frequency and percentages were used to describe the categorical variables. The data were shown using tables and graphs. Baseline characteristics of patients of \u226418 years vs. &amp;gt;18 years were compared using the Mann\u2013Whitney <jats:italic>U<\/jats:italic>-test for continuous variables and the Chi-square or Fisher exact test for categorical data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a female predominance with female to male ratio of 1.3. Compared to Group 1 (children and adolescents of age\u2009\u2264\u200918 years), more patients in Group 2(adults of age\u2009&amp;gt;\u200918 years) experienced symptoms (<jats:italic>p<\/jats:italic>-value\u2009&amp;lt;\u20090.001). The most common symptoms in adults were easy fatigability and dyspnea (63.2% of adult patients), while the most common symptom in children was recurrent respiratory tract infections (23.8%). Patients in Group 2 had greater pulmonary artery systolic pressure than those in Group 1 (<jats:italic>p<\/jats:italic>-value\u2009&amp;lt;\u20090.001). Overall, 88.9% of patients attained immediate success; there was no statistically significant difference between the two groups in immediate success rate (<jats:italic>p<\/jats:italic>\u2009=\u20090.52; Group 1 85.7% vs. Group 2 91.2%). Overall, patients' median length of hospital stay was 2 days (IQR, 2\u20132.5 days). There was no statistically significant difference between the two groups' median hospital stays [Group 1: 2 (IQR, 2\u20132.5) and Group 2: 2.5 (IQR 2\u20132.5); <jats:italic>P<\/jats:italic>-value\u2009=\u20090.111]. 23.2% of patients experienced complications, with no significant difference between the two groups (Group 1 28.6% and Group 2 19.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.28). The most common complications for patients in Groups 1 and 2 were atrioventricular (AV) valve encroachment (4.8) and paroxysmal supraventricular tachycardia (SVT) (5.3%), respectively. The major complication rates in the two groups did not show a statistically significant difference. Group 1 had a rate of 4.8%, whereas Group 2 had a rate of 0% (<jats:italic>p<\/jats:italic>-value\u2009=\u20090.18). The length of stays significantly increased in both groups in the presence of complications (<jats:italic>p<\/jats:italic>-value\u2009&amp;lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study emphasized that Percutaneous Closure of ASD can be successfully performed in resource-limited settings with a high immediate success rate and minimal complications such as AV valve encroachment and paroxysmal SVT. Given that complications impact length of hospital stays, preventing them is crucial.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2025.1550693","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T06:55:11Z","timestamp":1739861711000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Percutaneous atrial septal defect closure in limited-resource setting: a decade-long experience from Ethiopia"],"prefix":"10.3389","volume":"12","author":[{"given":"Mohammed","family":"Nasir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kefelegn","family":"Dejene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Bedru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sura","family":"Markos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.2214\/AJR.10.4277","article-title":"Embryology and developmental defects of the interatrial septum","volume":"195","author":"Rojas","year":"2010","journal-title":"Am J Roentgenol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/ije\/dyz009","article-title":"Global birth prevalence of congenital heart defects 1970\u20132017: updated systematic review and meta-analysis of 260 studies","volume":"48","author":"Liu","year":"2019","journal-title":"Int J Epidemiol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s12471-015-0663-z","article-title":"Secundum atrial septal defect in adults: a practical review and recent developments","volume":"23","author":"Kuijpers","year":"2015","journal-title":"Neth Heart J"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1016\/S0140-6736(13)62145-5","article-title":"Atrial septal defects","volume":"383","author":"Geva","year":"2014","journal-title":"Lancet"},{"key":"B5","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.ccl.2020.04.001","article-title":"Atrial septal defect","volume":"38","author":"Bradley","year":"","journal-title":"Cardiol Clin"},{"key":"B6","doi-asserted-by":"publisher","first-page":"S2874","DOI":"10.21037\/jtd.2018.08.111","article-title":"Atrial septal defect closure: indications and contra-indications","volume":"10","author":"Fraisse","year":"2018","journal-title":"J Thorac Dis"},{"key":"B7","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3389\/fcvm.2019.00185","article-title":"Predictors of the need for an atrial septal defect closure at very young age","volume":"6","author":"Tangh\u00f6j","year":"2020","journal-title":"Front Cardiovasc Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"S2931","DOI":"10.21037\/jtd.2018.07.116","article-title":"Surgical closure of atrial septal defects","volume":"10","author":"Liava\u2019a","year":"2018","journal-title":"J Thorac Dis"},{"key":"B9","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1136\/hrt.71.3.224","article-title":"Natural history of secundum atrial septal defect in adults after medical or surgical treatment: a historical prospective study","volume":"71","author":"Shah","year":"","journal-title":"Br Heart J"},{"key":"B10","first-page":"1","article-title":"Atrial septal defect guideline","author":"McGill-Lane","year":"2016","journal-title":"PedHeart Resource"},{"key":"B11","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1136\/heart.87.3.256","article-title":"Natural history of growth of secundum atrial septal defects and implications for transcatheter closure","volume":"87","author":"McMahon","year":"2002","journal-title":"Heart"},{"key":"B12","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S2352-4642(19)30402-X","article-title":"Global, regional, and national burden of congenital heart disease, 1990\u20132017: a systematic analysis for the global burden of disease study 2017","volume":"4","author":"Zimmerman","year":"2020","journal-title":"Lancet Child Adolesc Health"},{"key":"B13","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1093\/eurheartj\/ehy166","article-title":"Outcome of congenital heart disease with modern cardiac care","volume":"39","author":"L\u00fcscher","year":"2018","journal-title":"Eur Heart J"},{"key":"B14","doi-asserted-by":"publisher","first-page":"2660","DOI":"10.1093\/eurheartj\/ehab646","article-title":"Atrial septal defect in adulthood: a new paradigm for congenital heart disease","volume":"43","author":"Brida","year":"2022","journal-title":"Eur Heart J"},{"key":"B15","doi-asserted-by":"publisher","first-page":"156","DOI":"10.4274\/TP.2022.46330","article-title":"Evaluation of complications associated with cardiac catheterization: a single-center experience","volume":"3","author":"Yava\u015f Abal\u0131","year":"2022","journal-title":"Trends Pediatr"},{"key":"B16","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.kjms.2018.05.001","article-title":"Recent review of transcatheter closure of atrial septal defect","volume":"34","author":"Yang","year":"2018","journal-title":"Kaohsiung J Med Sci"},{"key":"B17","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1055\/s-2001-19010","article-title":"Surgical management of complications caused by transcatheter ASD closure","volume":"49","author":"Mellert","year":"2001","journal-title":"Thorac Cardiovasc Surg"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1016\/j.ejcts.2009.12.021","article-title":"Surgery for complications of trans-catheter closure of atrial septal defects: a multi-institutional study from the European congenital heart surgeons association","volume":"37","author":"Sarris","year":"2010","journal-title":"Eur J Cardiothorac Surg"},{"key":"B19","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/j.1747-0803.2007.00091.x","article-title":"Transcatheter versus surgical closure of secundum atrial septal defect in adults: impact of age at intervention. A concurrent matched comparative study","volume":"2","author":"Rosas","year":"2007","journal-title":"Congenit Heart Dis"},{"key":"B20","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1007\/s00246-012-0413-6","article-title":"Percutaneous atrial septal defect closure in infants and toddlers: predictors of success","volume":"34","author":"Petit","year":"2013","journal-title":"Pediatr Cardiol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1253\/circj.CJ-11-1379","article-title":"Device closure of atrial septal defect\u2013immediate and mid-term results\u2013","volume":"76","author":"Ueda","year":"2012","journal-title":"Circ J"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40064-016-3552-z","article-title":"Efficacy and safety of transcatheter closure in adults with large or small atrial septal defects","volume":"5","author":"Meyer","year":"2016","journal-title":"Springerplus"},{"key":"B23","doi-asserted-by":"publisher","first-page":"975","DOI":"10.4070\/kcj.2018.0391","article-title":"Procedural, early and long-term outcomes after percutaneous closure of atrial septal defect: comparison between large and very large atrial septal defect groups","volume":"49","author":"Jung","year":"2019","journal-title":"Korean Circ J"},{"key":"B24","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.21037\/tp-23-260","article-title":"Gender differences in congenital heart defects: a narrative review","volume":"12","author":"Pugnaloni","year":"2023","journal-title":"Transl Pediatr"},{"key":"B25","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.amjcard.2007.10.035","article-title":"Predictors of atrial arrhythmias after device closure of secundum type atrial septal defects in adults","volume":"101","author":"Silversides","year":"2008","journal-title":"Am J Cardiol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13019-020-1051-3","article-title":"Transcatheter and intraoperative device closure of atrial septal defect in infants under three years of age","volume":"15","author":"Han","year":"2020","journal-title":"J Cardiothorac Surg"},{"key":"B27","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S0735-1097(03)00589-8","article-title":"Transcatheter closure of atrial septal defect in young children: results and follow-up","volume":"42","author":"Butera","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"e004212","DOI":"10.1161\/CIRCINTERVENTIONS.116.004212","article-title":"Closure of secundum atrial septal defects with the AMPLATZER septal occluder: a prospective, multicenter, post-approval study","volume":"10","author":"Turner","year":"2017","journal-title":"Circ: Cardiovasc Interventions"},{"key":"B29","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.ehj.2018.09.003","article-title":"Short-term outcomes after surgical versus trans catheter closure of atrial septal defects; a study from Iran","volume":"70","author":"Askari","year":"2018","journal-title":"Egypt Heart"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1016\/S0735-1097(02)01862-4","article-title":"Comparison between transcatheter and surgical closure of secundum atrial septal defect in children and adults: results of a multicenter nonrandomized trial","volume":"39","author":"Du","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"851","DOI":"10.4070\/kcj.2016.46.6.851","article-title":"Comparison of transcatheter atrial septal defect closure in children, adolescents and adults: differences, challenges and short-, mid-and long-term results","volume":"46","author":"Saritas","year":"2016","journal-title":"Korean Circ J"},{"key":"B32","doi-asserted-by":"publisher","first-page":"S2909","DOI":"10.21037\/jtd.2018.02.19","article-title":"Transcatheter closure of atrial septal defect: principles and available devices","volume":"10","author":"Jung","year":"2018","journal-title":"J Thorac Dis"},{"key":"B33","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1002\/ccd.26585","article-title":"The influence of deficient retro-aortic rim on technical success and early adverse events following device closure of secundum atrial septal defects: an analysis of the IMPACT registry\u00ae","volume":"89","author":"O\u2019Byrne","year":"2017","journal-title":"Catheter Cardiovasc Interv"},{"key":"B34","doi-asserted-by":"publisher","first-page":"198","DOI":"10.3390\/jcm13010198","article-title":"Outcomes following closure of Secundum atrial septal defect in children \u226415\u2005kg in a French tertiary centre","volume":"13","author":"Pilard","year":"2023","journal-title":"J Clin Med"},{"key":"B35","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1017\/S104795111100093X","article-title":"Device closure of atrial septal defect: medium-term outcome with special reference to complications","volume":"22","author":"Sadiq","year":"2012","journal-title":"Cardiol Young"},{"key":"B36","doi-asserted-by":"publisher","first-page":"40","DOI":"10.15171\/jcvtr.2016.07","article-title":"Device closure in adults with atrial septal defect in Shiraz, a single center registry","volume":"8","author":"Ostovan","year":"2016","journal-title":"J Cardiovasc Thorac Res"},{"key":"B37","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.ahj.2015.02.010","article-title":"Cost comparison of transcatheter and operative closures of ostium secundum atrial septal defects","volume":"169","author":"O\u2019Byrne","year":"2015","journal-title":"Am Heart J"},{"key":"B38","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1046\/j.1540-8183.2003.01006.x","article-title":"ASD Closure with the amplatzer device","volume":"16","author":"Faella","year":"2003","journal-title":"J Interv Cardiol"},{"key":"B39","first-page":"220","article-title":"Closure of atrial septal defects in children: surgery versus amplatzer\u00ae device implantation","volume":"31","author":"Bialkowski","year":"2004","journal-title":"Tex Heart Inst J"},{"key":"B40","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.hlc.2013.07.020","article-title":"Transcatheter closure of secundum atrial septal defects: results in patients with large and extreme defects. Heart","volume":"23","author":"Romanelli","year":"2014","journal-title":"Lung and Circulation"},{"key":"B41","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/S2214-1235(15)30126-5","article-title":"Feasibility, safety and efficacy of percutaneous atrial septal defect closure in infants","volume":"21","author":"Ribeiro","year":"2013","journal-title":"Revista Brasileira de Cardiologia Invasiva"},{"key":"B42","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/j.ahj.2008.06.008","article-title":"Treatment of isolated secundum atrial septal defects: impact of age and defect morphology in 1,013 consecutive patients","volume":"156","author":"Butera","year":"2008","journal-title":"Am Heart J"},{"key":"B43","first-page":"CR612","article-title":"Transcatheter closure as an alternative and equivalent method to the surgical treatment of atrial septal defect in adults: comparison of early and late results","volume":"15","author":"Suchon","year":"2009","journal-title":"Med Sci Monit"},{"key":"B44","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s00246-016-1507-3","article-title":"Early complications after percutaneous closure of atrial septal defect in infants with procedural weight less than 15\u2005kg","volume":"38","author":"Tangh\u00f6j","year":"2017","journal-title":"Pediatr Cardiol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"2215490","DOI":"10.1080\/14017431.2023.2215490","article-title":"Atrial septal defect patients have an elevated risk for infective endocarditis","volume":"57","author":"Muroke","year":"2023","journal-title":"Scand Cardiovasc J"},{"key":"B46","doi-asserted-by":"publisher","first-page":"377","DOI":"10.4244\/EIJV7I3A63","article-title":"Percutaneous versus surgical closure of secundum atrial septal defects: a systematic review and meta-analysis of currently available clinical evidence","volume":"7","author":"Butera","year":"2011","journal-title":"EuroIntervention"},{"key":"B47","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.ijcard.2017.03.073","article-title":"Treatment options for the closure of secundum atrial septal defects: a systematic review and meta-analysis","volume":"241","author":"Villablanca","year":"2017","journal-title":"Int J Jof Cardiol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.amjcard.2008.10.018","article-title":"Closure of atrial septal defect with the Amplatzer septal occluder in adults","volume":"103","author":"Majunke","year":"2009","journal-title":"Am J Cardiol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.jcin.2015.09.028","article-title":"Transcatheter versus surgical closure of atrial septal defects in children: a value comparison","volume":"9","author":"Ooi","year":"2016","journal-title":"JACC: Cardiovasc Interv"},{"key":"B50","doi-asserted-by":"publisher","first-page":"406","DOI":"10.5152\/TurkArchPediatr.2022.21307","article-title":"Transcatheter closure of atrial septal defect in children: single-center experience, mid-term follow-up results","volume":"57","author":"\u00d6zbay","year":"2022","journal-title":"Turk Arch Pediatr"},{"key":"B51","doi-asserted-by":"publisher","first-page":"661","DOI":"10.5152\/TurkArchPediatr.2022.22098","article-title":"Early and mid-term follow-up results after transcatheter closure of Secundum atrial septal defect","volume":"57","author":"K\u0131l\u0131n\u00e7","year":"2022","journal-title":"Turk Arch Pediatr"},{"key":"B52","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ahj.2005.02.051","article-title":"Percutaneous versus surgical closure of secundum atrial septal defect: comparison of early results and complications","volume":"151","author":"Butera","year":"2006","journal-title":"Am Heart J"},{"key":"B53","doi-asserted-by":"publisher","first-page":"212","DOI":"10.4103\/jpcs.jpcs_30_21","article-title":"Clinical profile of patients of ASD device closure with special reference to short and intermediate term complications","volume":"7","author":"Gaidhane","year":"2021","journal-title":"J Pract Cardiovasc Sci"},{"key":"B54","doi-asserted-by":"publisher","first-page":"76","DOI":"10.14503\/THIJ-16-6018","article-title":"New pulmonary valvuloplasty technique by use of an hourglass-shaped balloon in 3 adults with severe pulmonary valve stenosis","volume":"45","author":"Kilic","year":"2018","journal-title":"Tex Heart Inst J"},{"key":"B55","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1016\/j.jtcvs.2007.06.018","article-title":"Device closure of atrial septal defects with the amplatzer septal occluder: safety and outcome in infants","volume":"134","author":"Diab","year":"2007","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B56","doi-asserted-by":"publisher","first-page":"17133","DOI":"10.26717\/BJSTR.2019.23.003847","article-title":"Long-term follow-up after transcatheter closure of atrial septal defect in children","volume":"23","author":"Sluysmans","year":"2019","journal-title":"Biomed J Sci Tech Res"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1002\/ccd.24875","article-title":"Short and long term complications of device closure of atrial septal defect and patent foramen ovale: meta-analysis of 28,142 patients from 203 studies","volume":"82","author":"Abaci","year":"2013","journal-title":"Catheter Cardiovasc Interv"},{"key":"B58","doi-asserted-by":"publisher","first-page":"0102","DOI":"10.17352\/2455-2976.000061","article-title":"Surgical management of embolised occlude devices and its complications-single centre experience of ten years at grant medical college, mumbai, maharashtra","volume":"5","author":"Nagre","year":"2018","journal-title":"J Cardiovasc Med Cardiol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/S0022-5223(99)70013-9","article-title":"Comparison of results and complications of surgical and Amplatzer device closure of atrial septal defects","volume":"118","author":"Berger","year":"1999","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B60","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1007\/s00246-001-0010-6","article-title":"Comparison of atrial septal defect closure using Amplatzer septal occluder with surgery","volume":"23","author":"Durongpisitkul","year":"2002","journal-title":"Pediatr Cardiol"},{"key":"B61","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1016\/S0735-1097(02)01711-4","article-title":"Early and late complications associated with transcatheter occlusion of secundum atrial septal defect","volume":"39","author":"Chessa","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1080\/07853890.2023.2178669","article-title":"Outcome of transcatheter atrial septal defect closure in a nationwide cohort","volume":"55","author":"Muroke","year":"2023","journal-title":"Ann Med"},{"key":"B63","doi-asserted-by":"publisher","first-page":"584236","DOI":"10.1155\/2012\/584236","article-title":"Transcatheter closure of atrial septal defects in children, middle-aged adults, and older adults: failure rates, early complications; and balloon sizing effects","volume":"1","author":"Vijarnsorn","year":"2012","journal-title":"Cardiol Res Pract"},{"key":"B64","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1007\/s00246-018-1914-8","article-title":"Recent experience and follow-up after surgical closure of secundum atrial septal defect in 120 children","volume":"39","author":"De Beco","year":"2018","journal-title":"Pediatr Cardiol"},{"key":"B65","first-page":"323","article-title":"Cardiac dysrhythmias after transcatheter closure of ASD with Amplatzer device","volume":"47","author":"\u00c7eliker","year":"2005","journal-title":"Turk J Pediatr"},{"key":"B66","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/S0300-8932(03)76882-1","article-title":"Percutaneous catheter closure of atrial septal defect. Short-term and mid-term results","volume":"56","author":"Bialkowski","year":"2003","journal-title":"Rev Esp Cardiol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"6598637","DOI":"10.1155\/2019\/6598637","article-title":"Transcatheter atrial septal defect closure in children with and without fluoroscopy: a comparison","volume":"2019","author":"Ackermann","year":"2019","journal-title":"J Interv Cardiol"},{"key":"B68","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.5603\/KP.a2018.0113","article-title":"Transcatheter closure of atrial septal defects type 2 in children under three years of age","volume":"76","author":"Knop","year":"2018","journal-title":"Kardiol Pol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1253\/circj.CJ-16-0904","article-title":"Comparison of clinical outcomes after transcatheter vs. Minimally invasive cardiac surgery closure for atrial septal defect","volume":"81","author":"Kodaira","year":"2017","journal-title":"Circ J"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1550693\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T06:55:16Z","timestamp":1739861716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1550693\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,18]]},"references-count":69,"alternative-id":["10.3389\/fcvm.2025.1550693"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2025.1550693","relation":{},"ISSN":["2297-055X"],"issn-type":[{"value":"2297-055X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,18]]},"article-number":"1550693"}}