{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:48:43Z","timestamp":1753890523449,"version":"3.41.2"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Aortic angiosarcoma is a rare disease with atypical clinical symptoms. It often initially presents with embolic phenomena, such as lower limb arterial embolism, visceral embolism, or cerebral embolism, or as renovascular hypertension.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>There are no reported cases in the literature of spinal cord embolism caused by this condition. We report a case of a 76-year-old female patient whose abdominal CT showed a soft tissue mass in the left hip, involving the sacrum and iliac bone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Aortic CTA revealed irregular filling defects in the aortic arch and descending aorta, highly suggestive of a tumor. A biopsy of the left hip mass confirmed the diagnosis of angiosarcoma. Immunohistochemistry results were positive for Vimentin, CD31, and ERG. Based on the patient's CTA findings, a diagnosis of aortic angiosarcoma with left hip soft tissue metastasis was made. The patient developed paraplegia and lower limb arterial embolism and died shortly afterward. This article briefly reviews the literature on aortic angiosarcoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The purpose of this case report is to highlight the importance of monitoring common embolic sites in clinical practice, while also considering the possibility of rare sites, such as spinal cord embolism.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2025.1551262","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T05:25:26Z","timestamp":1745904326000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Aortic angiosarcoma leading to paraplegia: a case report"],"prefix":"10.3389","volume":"12","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiubo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1053\/j.sult.2011.10.001","article-title":"Aortic tumors","volume":"33","author":"Restrepo","year":"2012","journal-title":"Semin Ultrasound CT MR"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1016\/j.jvs.2019.09.030","article-title":"Predictors of survival in malignant aortic tumors","volume":"71","author":"Vacirca","year":"2020","journal-title":"J Vasc Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"101230","DOI":"10.1016\/j.jvscit.2023.101230","article-title":"Intimal angiosarcoma of the descending aorta presenting as atheroembolism: case report and description of intravascular biopsy","volume":"9","author":"Bartolome Sanchez","year":"2023","journal-title":"J Vasc Surg Cases Innov Tech"},{"key":"B4","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1471-2342-13-25","article-title":"Imaging features of primary sarcomas of the great vessels in CT, MRI and PET\/CT: a single-center experience","volume":"13","author":"Von Falck","year":"2013","journal-title":"BMC Med Imaging"},{"key":"B5","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1148\/rg.2021200184","article-title":"Intimal sarcoma of the great vessels","volume":"41","author":"Ropp","year":"2021","journal-title":"Radiographics"},{"key":"B6","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.jvs.2004.06.035","article-title":"Intimal angiosarcoma of the aorta: report of a case and review of the literature","volume":"40","author":"Thalheimer","year":"2004","journal-title":"J Vasc Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1053\/j.sult.2011.06.001","article-title":"Imaging sarcomas of the great vessels and heart","volume":"32","author":"Bendel","year":"2011","journal-title":"Semin Ultrasound CT MR"},{"key":"B8","doi-asserted-by":"publisher","first-page":"492.e5","DOI":"10.1016\/j.avsg.2012.12.014","article-title":"Diagnosis and treatment of a symptomatic primary thoracic aortic tumor: endovascular exclusion to prevent recurrent embolization","volume":"28","author":"Peinado Cebrian","year":"2014","journal-title":"Ann Vasc Surg"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.1002\/1097-0142(19911001)68:7%3C1622::aid-cncr2820680726%3E3.0.co;2-b","article-title":"Mesenteric infarction secondary to tumor emboli from primary aortic sarcoma. 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