{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T14:27:25Z","timestamp":1754144845995,"version":"3.41.2"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Primary cardiac tumors in the fetal and neonatal populations are rare. In neonates, these tumors may present with a range of clinical manifestations, from asymptomatic cases to severe arrhythmias, valvular obstruction, and cardiac dysfunction. This report describes a case of fatal malignant arrhythmia caused by a cardiac tumor in an 8-day-old neonate. The electrocardiogram at birth revealed multiple abnormalities, including ST-T segment alterations, intraventricular conduction block, and bundle branch block. By the sixth postnatal day, the patient developed rapid, polymorphic malignant ventricular arrhythmias. Despite aggressive treatment, the neonate ultimately suffered sudden cardiac death. This case underscores the potentially fatal risk of arrhythmias associated with cardiac tumors.<\/jats:p>","DOI":"10.3389\/fcvm.2025.1552916","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T05:35:29Z","timestamp":1752644129000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Electrical alternans of the Q-T interval and fatal arrhythmias caused by neonatal cardiac tumor: a case report"],"prefix":"10.3389","volume":"12","author":[{"given":"Ge","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongguang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqi","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hairui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1111\/j.1556-4029.2012.02136.x","article-title":"A case of sudden infant death due to a primary cardiac sarcoma","volume":"57","author":"Cascini","year":"2012","journal-title":"J Forensic Sci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1111\/j.1651-2227.1990.tb11372.x","article-title":"Cardiac myxoma as the cause of death in an infant","volume":"79","author":"Hals","year":"1990","journal-title":"Acta Paediatr Scand"},{"key":"B3","doi-asserted-by":"publisher","first-page":"47","DOI":"10.2174\/1874192401307010047","article-title":"Primary cardiac fibroma and cardiac conduction system alterations in a case of sudden death of a 4-month-old infant","volume":"7","author":"Mecchia","year":"2013","journal-title":"Open Cardiovasc Med J"},{"key":"B4","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/0002-9149(72)90133-6","article-title":"Clinical presentation of rhabdomyoma of the heart in infancy and childhood","volume":"30","author":"Shaher","year":"1972","journal-title":"Am J Cardiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1056\/NEJM196704272761705","article-title":"Rhabdomyoma of the heart. 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