{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:50:24Z","timestamp":1753890624575,"version":"3.41.2"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Infective endocarditis (IE) is a severe and frequently fatal complication in dialysis patients, particularly those with vascular access devices such as arteriovenous grafts (AVGs) or fistulas. We describe the case of a 55-year-old male with end-stage renal disease (ESRD) on peritoneal dialysis (PD), who developed advanced IE following repeated punctures of an AVG. The patient initially presented with fever, erythema, and swelling at the graft site, which progressed to bacteremia due to <jats:italic>Staphylococcus aureus<\/jats:italic>. Despite completing a full course of antibiotics and undergoing both mitral and aortic valve replacement, the patient suffered recurrent episodes of acute heart failure requiring repeated hospital admissions. This rare case highlights the substantial risk of IE in dialysis patients with vascular access devices and the importance of early detection and timely intervention. The clinical difficulties and economic strain associated with IE management in this population point to the need for close surveillance, rapid diagnosis, and individualized treatment plans to improve outcomes and control healthcare expenditures.<\/jats:p>","DOI":"10.3389\/fcvm.2025.1570949","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T05:21:29Z","timestamp":1750656089000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Infective endocarditis following arteriovenous graft in a peritoneal dialysis patient"],"prefix":"10.3389","volume":"12","author":[{"given":"Fangzhong","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuchun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuping","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuangqing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1016\/j.jacc.2021.02.014","article-title":"Infective endocarditis in patients on chronic hemodialysis","volume":"77","author":"Peric\u00e0s","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"100680","DOI":"10.1016\/j.cpcardiol.2020.100680","article-title":"Infective endocarditis and its short and long-term prognosis in hemodialysis patients: a systematic review and meta-analysis","volume":"46","author":"Sadeghi","year":"2021","journal-title":"Curr Probl Cardiol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.2215\/CJN.02320317","article-title":"Risk of infective endocarditis in patients with end stage renal disease","volume":"12","author":"Chaudry","year":"2017","journal-title":"Clin J Am Soc Nephro"},{"key":"B4","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1177\/1129729820970783","article-title":"Infective endocarditis in hemodialysis patients: a 10-year observational single center study","volume":"23","author":"Bentata","year":"2022","journal-title":"J Vasc Access"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e29182","DOI":"10.7759\/cureus.29182","article-title":"Pathogenesis, diagnosis, antimicrobial therapy, and management of infective endocarditis, and its complications","volume":"14","author":"Kamde","year":"2022","journal-title":"Cureus"},{"key":"B6","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1159\/000540513","article-title":"Infective endocarditis in patients receiving hemodialysis: a current review","volume":"10","author":"Ding","year":"2024","journal-title":"Kidney Dis"},{"key":"B7","doi-asserted-by":"publisher","first-page":"51","DOI":"10.5414\/CN111117","article-title":"Risk factors for infective endocarditis in patients receiving hemodialysis: a propensity score matched cohort study","volume":"100","author":"Al-Chalabi","year":"2023","journal-title":"Clin Nephrol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/s1001-9294(10)60037-5","article-title":"Diagnosis and treatment of infective endocarditis in chronic hemodialysis patients","volume":"25","author":"Tao","year":"2010","journal-title":"Chin Med Sci J"},{"key":"B9","doi-asserted-by":"publisher","first-page":"3948","DOI":"10.1093\/eurheartj\/ehad193","article-title":"2023 Esc guidelines for the management of endocarditis","volume":"44","author":"Delgado","year":"2023","journal-title":"Eur Heart J"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1161\/CIR.0000000000000296","article-title":"Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications: a scientific statement for healthcare professionals from the American Heart Association","volume":"132","author":"Baddour","year":"2015","journal-title":"Circulation"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e69924","DOI":"10.7759\/cureus.69924","article-title":"A case of native mitral valve infective endocarditis in a chronic dialysis patient: the importance of vigilance","volume":"16","author":"Myint","year":"2024","journal-title":"Cureus"},{"key":"B12","doi-asserted-by":"publisher","first-page":"5948","DOI":"10.3390\/jcm12185948","article-title":"Impact of chronic kidney disease and dialysis on outcome after surgery for infective endocarditis","volume":"12","author":"Elderia","year":"2023","journal-title":"J Clin Med"},{"key":"B13","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1002\/clc.22688","article-title":"Trends and outcomes of infective endocarditis in patients on dialysis","volume":"40","author":"Bhatia","year":"2017","journal-title":"Clin Cardiol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s12872-023-03675-0","article-title":"Comparative analysis of infective endocarditis in hemodialysis versus non-hemodialysis patients in Iran: implications for clinical practice and future research","volume":"24","author":"Zolfaghari","year":"2024","journal-title":"BMC Cardiovasc Disord"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.3390\/healthcare12161631","article-title":"Infective endocarditis in patients with end-stage renal disease on dialysis: epidemiology, risk factors, diagnostic challenges, and management approaches","volume":"12","author":"Issa","year":"2024","journal-title":"Healthcare"}],"container-title":["Frontiers in Cardiovascular Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1570949\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T05:21:30Z","timestamp":1750656090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcvm.2025.1570949\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,23]]},"references-count":15,"alternative-id":["10.3389\/fcvm.2025.1570949"],"URL":"https:\/\/doi.org\/10.3389\/fcvm.2025.1570949","relation":{},"ISSN":["2297-055X"],"issn-type":[{"type":"electronic","value":"2297-055X"}],"subject":[],"published":{"date-parts":[[2025,6,23]]},"article-number":"1570949"}}