{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:41:51Z","timestamp":1757623311799,"version":"3.44.0"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study was conducted to investigate the association between previous spontaneous abortion and preeclampsia among pregnant women in Rwanda.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case (preeclampsia)-control (healthy pregnant women) study with 188 women per group was conducted at Kacyiru Hospital in Kigali, Rwanda. Data were collected using questionnaires, and multivariate binary analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference in age and parity between the case and control groups. In the case group, 29 (15.4%) and 13 (6.9%) women and 16 (8.5%) and 2 (1.1%) women in the control group had a history of one abortion or two or more abortions, respectively. A multivariate binary regression analysis revealed that women with a history of abortion had a higher risk of preeclampsia compared to their peers who had no history of abortion [adjusted odds ratio (AOR)\u2009=\u20092.66, 95% confidence interval (CI): 1.35\u20135.27]. Women with one past abortion (AOR\u2009=\u20092.33, 95% CI: 1.12\u20134.86) and those with two or more past abortions (AOR\u2009=\u20098.29, 95% CI: 1.73\u201339.63) had a higher risk of preeclampsia. Women with a history of preeclampsia who were rural residents or had an increasing body mass index showed a higher risk of preeclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A history of abortion is associated with preeclampsia. Women with a history of abortion have to receive more frequent care, looking for the development of pre-eclampsia.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fcvm.2025.1572300","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T05:38:25Z","timestamp":1757396305000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Previous abortion and preeclampsia in Kigali, Rwanda: a case-control study"],"prefix":"10.3389","volume":"12","author":[{"given":"Anas 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