{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:00:25Z","timestamp":1787238025166,"version":"build-2736575974"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) typically manifests in the first weeks of life. We report a 28-year-old woman with atrial fibrillation and pulmonary hypertension which were later found to be associated with ALCAPA syndrome. Despite a history free of traditional cardiovascular risk factors, her symptoms included exercise intolerance, palpitations, and an ischemic stroke. Echocardiography and further examination revealed pulmonary artery origin of the left coronary artery and extensive collateral formation between the left and right coronary arteries, contributing to her symptoms.<\/jats:p>","DOI":"10.3389\/fcvm.2025.1573539","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T01:39:01Z","timestamp":1747013941000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: a 28-year-old female with anomalous origin of the left coronary artery from the pulmonary artery syndrome presented as atrial fibrillation and pulmonary hypertension"],"prefix":"10.3389","volume":"12","author":[{"given":"Keyue","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiqi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongtai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1002\/clc.20848","article-title":"Anomalous origin of the left coronary artery from the pulmonary artery in adults: a comprehensive review of 151 adult cases and a new diagnosis in a 53-year-old woman","volume":"34","author":"Yau","year":"2011","journal-title":"Clin Cardiol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2805","DOI":"10.1093\/eurheartj\/ehad327","article-title":"Coronary steal: how many thieves are out there?","volume":"44","author":"Achim","year":"2023","journal-title":"Eur Heart J"},{"key":"B3","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1148\/rg.292085059","article-title":"ALCAPA syndrome: not just a pediatric disease1","volume":"29","author":"Pena","year":"2009","journal-title":"Radiographics"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1801897","DOI":"10.1183\/13993003.01897-2018","article-title":"Pulmonary hypertension due to left heart disease","volume":"53","author":"Vachi\u00e9ry","year":"2019","journal-title":"Eur Respir J"},{"key":"B5","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.ijcard.2018.02.082","article-title":"Anomalous left coronary artery from the pulmonary artery (ALCAPA) diagnosed in adulthood: varied clinical presentation, therapeutic approach and outcome","volume":"261","author":"Boutsikou","year":"2018","journal-title":"Int J Cardiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.3390\/jpm13111561","article-title":"Anomalous left coronary artery from the pulmonary artery: how to diagnose and treat","volume":"13","author":"Blickenstaff","year":"2023","journal-title":"J Pers Med"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/ehjcr\/ytaa318","article-title":"Late adult presentation of ALCAPA syndrome: need for a new clinical classification? 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