{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T11:27:39Z","timestamp":1785583659535,"version":"3.56.0"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Cardiovasc. Med."],"abstract":"<jats:p>Intra-aortic balloon pump (IABP) counterpulsation generates pressure changes that are primarily influenced by aortic compliance, an index of arterial elasticity that varies widely among patients with cardiovascular disease. However, the potential role of aortic compliance in determining IABP efficacy remains poorly understood. We present the case of an 80-year-old man with severe aortic stenosis and pneumonia who was admitted with generalized fatigue and worsening dyspnea. He developed refractory Society for Cardiovascular Angiography &amp;amp; Interventions stage D cardiogenic shock despite multiple vasopressors. In this patient, who had low aortic compliance (0.62\u20130.81\u2005ml\/mmHg), IABP initiation resulted in immediate hemodynamic improvement through enhanced diastolic augmentation and systolic unloading, leading to rapid reversal of both hypoperfusion and pulmonary congestion. Following successful weaning from vasopressors and IABP removal, the patient underwent transcatheter aortic valve replacement without temporary mechanical circulatory support-related complications. The notable hemodynamic improvement observed in this case highlights the potential importance of aortic compliance as a key determinant of IABP efficacy in elderly patients with cardiogenic shock, suggesting that aortic compliance may help optimize patient selection for IABP support.<\/jats:p>","DOI":"10.3389\/fcvm.2025.1587383","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T05:33:07Z","timestamp":1751002387000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Intra-aortic balloon pump in a patient with refractory cardiogenic shock complicating severe aortic stenosis\u2014enhanced hemodynamic response with low aortic compliance"],"prefix":"10.3389","volume":"12","author":[{"given":"Issei","family":"Ota","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Sawada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Saku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruo","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1056\/NEJMoa1208410","article-title":"Intraaortic balloon support for myocardial infarction with cardiogenic shock","volume":"367","author":"Thiele","year":"2012","journal-title":"N Engl J Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1001\/jamainternmed.2022.2735","article-title":"Clinical outcomes and cost associated with an intravascular microaxial left ventricular assist device vs intra-aortic balloon pump in patients presenting with acute myocardial infarction complicated by cardiogenic shock","volume":"182","author":"Miller","year":"2022","journal-title":"JAMA Intern Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1161\/CIRCULATIONAHA.118.036614","article-title":"Impella support for acute myocardial infarction complicated by cardiogenic shock","volume":"139","author":"Schrage","year":"2019","journal-title":"Circulation"},{"key":"B4","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.jacc.2016.10.022","article-title":"Percutaneous mechanical circulatory support versus intra-aortic balloon pump in cardiogenic shock after acute myocardial infarction","volume":"69","author":"Ouweneel","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"e034645","DOI":"10.1161\/JAHA.123.034645","article-title":"Percutaneous microaxial ventricular assist device versus intra-aortic balloon pump for nonacute myocardial infarction cardiogenic shock","volume":"13","author":"Watanabe","year":"2024","journal-title":"J Am Heart Assoc"},{"key":"B6","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.amjcard.2023.06.082","article-title":"Trends in mechanical circulatory support use and outcomes of patients with cardiogenic shock in Japan, 2010 to 2020 (from a nationwide inpatient database study)","volume":"203","author":"Nishimoto","year":"2023","journal-title":"Am J Cardiol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1016\/j.jacc.2019.07.012","article-title":"Large-Artery stiffness in health and disease: JACC state-of-the-art review","volume":"74","author":"Chirinos","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/s1350-4533(02)00013-9","article-title":"Arterial compliance is a main variable determining the effectiveness of intra-aortic balloon counterpulsation: quantitative data from an in vitro study","volume":"24","author":"Papaioannou","year":"2002","journal-title":"Med Eng Phys"},{"key":"B9","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1111\/j.1525-1594.2004.00080.x","article-title":"New aspects on the role of blood pressure and arterial stiffness in mechanical assistance by intra-aortic balloon pump: in vitro data and their application in clinical practice","volume":"28","author":"Papaioannou","year":"2004","journal-title":"Artif Organs"},{"key":"B10","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1097\/00000542-197304000-00017","article-title":"Indirect measurement of left-atrial pressure in surgical patients\u2014pulmonary-capillary wedge and pulmonary-artery diastolic pressures compared with left-atrial pressure","volume":"38","author":"Lappas","year":"1973","journal-title":"Anesthesiology"},{"key":"B11","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1056\/NEJM197305102881901","article-title":"Intra-aortic balloon counterpulsation in cardiogenic shock. 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